CN102754669B - 一种杀灭跳蚤的药物 - Google Patents
一种杀灭跳蚤的药物 Download PDFInfo
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- XMAYWYJOQHXEEK-OZXSUGGESA-N (2R,4S)-ketoconazole Chemical compound C1CN(C(=O)C)CCN1C(C=C1)=CC=C1OC[C@@H]1O[C@@](CN2C=NC=C2)(C=2C(=CC(Cl)=CC=2)Cl)OC1 XMAYWYJOQHXEEK-OZXSUGGESA-N 0.000 claims abstract description 9
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- BLUAFEHZUWYNDE-NNWCWBAJSA-N artemisinin Chemical compound C([C@](OO1)(C)O2)C[C@H]3[C@H](C)CC[C@@H]4[C@@]31[C@@H]2OC(=O)[C@@H]4C BLUAFEHZUWYNDE-NNWCWBAJSA-N 0.000 claims abstract description 9
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- 238000000034 method Methods 0.000 claims description 7
- AXTGDCSMTYGJND-UHFFFAOYSA-N 1-dodecylazepan-2-one Chemical compound CCCCCCCCCCCCN1CCCCCC1=O AXTGDCSMTYGJND-UHFFFAOYSA-N 0.000 claims description 4
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Abstract
本发明公开了一种杀灭跳蚤的药物，属于卫生防疫技术领域。它由下述重量份的原料制成：苍术10-50，黄连20-80，青蒿素1-4，特比萘芬1-4，酮康唑1-4，蝎毒2-5，大蒜100-300，红糖500-1000。本发明使用安全，对人、畜无毒，无污染，且跳蚤死亡率高达98.7％。
Description
技术领域
本发明涉及一种杀灭跳蚤的药物，属于卫生防疫技术领域。
背景技术
跳蚤对人类的健康危害严重，跳蚤是多种疾病的产生和传播根源，可传播虱传斑疹伤寒、鼠疫、回归热等危险疾病，它携带鼠疫杆菌、痢疾杆菌、大肠杆菌、脊椎灰质火病毒和黄曲霉毒等40多种病原体，而且其分泌物和粪便中还含有多种致癌物质。虱子可受杀虫剂的影响，通常使用的化学杀虫剂主要为有机磷化合物及拟菊脂 类，施用这些杀虫剂不但杀死了害虫，也同时杀死了有益昆虫及害虫的天敌，造成了生态平衡的破坏，对人畜产生危害。 因此，开发杀灭跳蚤的药物非常有意义。
发明内容
为了克服上述现有杀灭跳蚤的化学药物的缺点，本发明的提供一种安全、环保的杀灭跳蚤的药物。
本发明的一种杀灭跳蚤的药物，由下述重量份的原料制成：由下述重量份的原料制成：苍术10-50，黄连20-80，青蒿素1-4，特比萘芬1-4，酮康唑1-4，蝎毒2-5，大蒜100-300，红糖500-1000。
本发明的一种杀灭跳蚤的药物的制备方法：按上述重量份称取原料，
其制法是：
第1步将：特比萘芬、酮康唑用75％乙醇溶解后加入月桂氮酮过滤除菌,再加75％乙醇，混合均匀，得到液体1，备用。
第2步将：蝎毒、青蒿素，混合，用75％乙醇溶解，得到液体2，备用，
第3步将：苍术、黄连、大蒜，用75％乙醇冷浸，过滤，得到液体3，，备用。
第4步将：液体1、2、3与红糖混合，干燥，就得到本发明的产品
使用方法：将本发明药物放于跳蚤将常出没的地方，跳蚤食用后行动缓慢、无力，3-4天后死亡，死亡率达92.7％。
以下以试验数据来进一步说明其有益效果。
检测环境条件：温度：20±2℃，相对湿度50％±4％；方箱型号：0.2m×0.2m×0.2m；
1、试虫：跳蚤，2周龄成虫，雌雄各半。
2、试验方法：
室内实验方法：
方箱装置试验方法：根据使用方法，取2克本发明杀灭跳蚤的药物放入玻璃方箱一角，对角放正常饲养用小鼠用料，中间放清洁进水海绵皿和模拟跳蚤屋。将跳蚤放入玻璃方箱装置，并计时，逐日观察试虫死亡数量， 取出死虫，直至全部试虫死亡。试验重复3次，设空白对照。
表1本发明药物诱杀跳蚤试验结果
| 试验天数(天) | 1 | 2 | 3 | 4 | 5 | 6 |
| 死亡率(％) | 54.1 | 67.9 | 74.3 | 82.5 | 92.4 | 98.7％ |
注：对照组试虫100只，试验6天死亡1只，死亡率为1％。
具体实施方式
实施例1：
一种杀灭跳蚤的药物，由下述重量份（克）的原料制成：由下述重量份的原料制成：苍术10，黄连20，青蒿素1，特比萘芬1，酮康唑1，蝎毒2，大蒜100，红糖500。
其制法是：
第1步将：特比萘芬、酮康唑用75％乙醇20ml溶解后加入月桂氮酮过滤除菌,再加75％乙醇至100ml并混合均匀，得到液体1，备用。
第2步将：蝎毒、青蒿素，混合，用75％乙醇20ml溶解，得到液体2，备用。
第3步将：苍术、黄连、大蒜，用75％乙醇500ml冷浸，过滤，得到液体3，备用。
第4步将：液体1、2、3与红糖混合，真空干燥，就得到本发明的产品。
实施例2：
本发明的一种杀灭跳蚤的药物，由下述重量份（克）的原料制成：由下述重量份的原料制成：苍术50，黄连80，青蒿素4，特比萘芬4，酮康唑4，蝎毒5，大蒜300，红糖1000。
其制法是：
第1步将：特比萘芬、酮康唑用75％乙醇40ml溶解后加入月桂氮酮过滤除菌,再加75％乙醇至200ml并混合均匀，得到溶液1，备用。
第2步将：蝎毒、青蒿素，混合，用75％乙醇40ml溶解，得到液体2，备用。
第3步将：苍术、黄连、大蒜，用75％乙醇1000ml冷浸，过滤，得到液体3，备用。
第3步将：溶液1、2、3与红糖混合，真空干燥，就得到本发明的产品。
Claims (1)
1.一种杀灭跳蚤的药物的制备方法，其特征是，
由下述重量份的原料制成：苍术10-50，黄连20-80，青蒿素1-4，特比萘芬1-4，酮康唑1-4，蝎毒2-5，大蒜100-300，红糖500-1000,
其制法是：
第1步将：特比萘芬、酮康唑用75％乙醇溶解后加入月桂氮酮过滤除菌,再加75％乙醇，混合均匀，得到液体1，备用，
第2步将：蝎毒、青蒿素，混合，用75％乙醇溶解，得到液体2，备用，
第3步将：苍术、黄连、大蒜，用75％乙醇冷浸，过滤，得到液体3，备用，
第4步将：液体1、2、3与红糖混合，干燥，就得到产品。
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| CN201210277246.4A CN102754669B (zh) | 2012-08-07 | 2012-08-07 | 一种杀灭跳蚤的药物 |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1110145A (zh) * | 1994-03-19 | 1995-10-18 | 舒毅 | 一种用于治疗皮肤病的蝎毒油 |
| CN1628520A (zh) * | 2004-09-22 | 2005-06-22 | 车维新 | 用于家庭宠物杀虫及灭菌的外用制剂 |
| CN101279064A (zh) * | 2008-05-28 | 2008-10-08 | 陈士芳 | 凹凸棒醇基灭虱制剂 |
| CN101313969A (zh) * | 2008-07-17 | 2008-12-03 | 王跃进 | 一种顽癣喷剂 |
| CN101564519A (zh) * | 2009-06-05 | 2009-10-28 | 中国人民解放军军事医学科学院军事兽医研究所 | 一种治疗宠物寄生虫、真菌、细菌感染的外用药剂及其制备方法 |
| CN102018944A (zh) * | 2010-05-07 | 2011-04-20 | 王红芳 | 防止昆虫和动物侵害人体的驱避剂及该驱避剂制成的贴片 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE80657B1 (en) * | 1996-03-29 | 1998-11-04 | Merial Sas | Insecticidal combination to control mammal fleas in particular fleas on cats and dogs |
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Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1110145A (zh) * | 1994-03-19 | 1995-10-18 | 舒毅 | 一种用于治疗皮肤病的蝎毒油 |
| CN1628520A (zh) * | 2004-09-22 | 2005-06-22 | 车维新 | 用于家庭宠物杀虫及灭菌的外用制剂 |
| CN101279064A (zh) * | 2008-05-28 | 2008-10-08 | 陈士芳 | 凹凸棒醇基灭虱制剂 |
| CN101313969A (zh) * | 2008-07-17 | 2008-12-03 | 王跃进 | 一种顽癣喷剂 |
| CN101564519A (zh) * | 2009-06-05 | 2009-10-28 | 中国人民解放军军事医学科学院军事兽医研究所 | 一种治疗宠物寄生虫、真菌、细菌感染的外用药剂及其制备方法 |
| CN102018944A (zh) * | 2010-05-07 | 2011-04-20 | 王红芳 | 防止昆虫和动物侵害人体的驱避剂及该驱避剂制成的贴片 |
Non-Patent Citations (4)
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| 吴泽全.青蒿—饲料与良药.《四川农业科技》.1990,(第04期),第27页. |
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