CN102735829A - Blood gas analyzer and using method thereof - Google Patents

Blood gas analyzer and using method thereof Download PDF

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Publication number
CN102735829A
CN102735829A CN201210252942XA CN201210252942A CN102735829A CN 102735829 A CN102735829 A CN 102735829A CN 201210252942X A CN201210252942X A CN 201210252942XA CN 201210252942 A CN201210252942 A CN 201210252942A CN 102735829 A CN102735829 A CN 102735829A
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pump housing
solenoid valve
reagent
liquid
needle
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CN201210252942XA
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CN102735829B (en
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侯兴凯
姚新宁
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Shenzhen Kang Li Biological Medicine Co., Ltd.
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MEIZHOU KANGLI HIGH-TECH Co Ltd
SHENZHEN MAIDICONG MEDICAL ELECTRONIC CO Ltd
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Priority to CN 201210252942 priority Critical patent/CN102735829B/en
Publication of CN102735829A publication Critical patent/CN102735829A/en
Priority to PCT/CN2013/074830 priority patent/WO2014015691A1/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/4925Blood measuring blood gas content, e.g. O2, CO2, HCO3
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The invention discloses a blood gas analyzer which comprises a needle valve arranged in a sampling frame, a sample box connected with the needle valve, a first pump body connected with the sample box, a waste liquid bag connected with the first pump body, a liquid detector connected with the needle valve and the second pump body, a third electromagnetic valve connected with the liquid detector, a first electromagnetic valve connected with the second pump body and a second pump body connected with the needle valve and the waste liquid bag, wherein in the sample box, one end of a front detector is connected with the needle valve, while the other end of the front detector is sequentially connected with a detection membrane pipe and a rear detector, and the rear detector is connected with the first pump body; the above parts are connected through flow pipes; a memory is connected with the detection membrane pipe through an electrode; and the first electromagnetic valve and the second electromagnetic valve are both provided with air inlets. According to the invention, a gas-liquid mixed calibration method in the prior art is replaced by liquid calibration, so that the method is more convenient for use, and faults caused by that liquid enters an air path are avoided, the fault probability is reduced, and the reliability of the analyzer is improved.

Description

A kind of blood gas analyzer and method of application thereof
Technical field
The present invention relates to the medical science field tests, relate in particular to a kind of blood gas analyzer and method of application thereof.
Background technology
Iontophoresis electrode was measured the passage calibration after the PCO2 of existing homemade blood gas analyzer, the calibration of PO2 electrode all adopted the different high gas of gas mixing ratio and two kinds of pressure gass of low gas through decompression, insulation, humidifying, and remaining electrode adopts the normal fluid calibration.In this calibration mode, stream divides gas circuit and liquid road, and the control of gas-liquid infall is comparatively complicated; Particularly under situation about breaking down; Calibration solution or cleaning fluid get into gas circuit and very easily damage solenoid valve, in addition, because the existence of gas cylinder; Instrument is not easy to make the portable or hand propelled of removable use, makes the standard fate defeated inconvenient; Because calibrating gas is a pressure gas, gas cylinder is bigger again, is not easy to transportation and use, and ability was available after pressure gas will pass through decompression, insulation, humidifying, and use is comparatively loaded down with trivial details.Therefore be badly in need of a kind of easy to use, reliable quality qi and blood analyser.
Summary of the invention
The purpose of this invention is to provide a kind of blood gas analyzer and method of application thereof; The method that replaces gas of the prior art and liquid mixing calibration through the liquid calibration; Use more convenient; Avoid having reduced the probability that breaks down, thereby improve the reliability of instrument because of liquid gets into the fault that gas circuit produces.
Technical scheme of the present invention is: a kind of blood gas analyzer comprises: place sampling stand needle-valve, connect said needle-valve sales kit (SK), connect said sales kit (SK) first pump housing, connect said first pump housing waste fluid bag, connect said needle-valve and second pump housing detector of liquid, through second solenoid valve be connected said second pump housing the 4th reagent bag, connect said detector of liquid the 3rd solenoid valve, connect this second pump housing first solenoid valve, through the 6th solenoid valve connect said detector of liquid the first reagent bag, through the 5th solenoid valve connect said detector of liquid the second reagent bag, through the 4th solenoid valve connect said detector of liquid the 3rd reagent bag and second pump housing of connection needle-valve and waste fluid bag; In the sales kit (SK), an end of preceding detecting device connects needle-valve, and the other end is joint detection film pipe and back detecting device successively, and back detecting device connects first pump housing; All passing through flow channel tube between aforementioned each parts connects; Storer is through electrode joint detection film pipe; In above-mentioned each reagent bag different liquid is housed, on first solenoid valve and the 3rd solenoid valve air intake opening is arranged all, when detector of liquid detects liquid; The closed electromagnetic valve of having opened that is used to extract liquid; The 3rd solenoid valve is opened, and air substitutes liquid and gets into flow channel tube, in the balance flow channel tube with the air pressure of space outerpace; Make the liquid in the flow channel tube get into the detection of detection film pipe smoothly, practiced thrift liquid simultaneously; When second solenoid valve is opened the extraction cleaning fluid, open first solenoid valve, air is got in the flow channel tube, air and cleaning fluid mix, and in flow channel tube, form the cleaning fluid of segmentation, clean more thorough.
Wherein, The 3rd solenoid valve, the 4th solenoid valve, the 5th solenoid valve and the 6th solenoid valve are set up in parallel, and connect the flow channel tube between second pump housing and the detector of liquid in order successively, and said the 3rd solenoid valve is near said second pump housing; Solenoid valve is swift in response; Switch is flexible, and control is automatically used easily blood gas analyzer.In the first reagent bag first reagent is arranged, in the second reagent bag second reagent is arranged, in first reagent and second reagent; The numerical value of target to be measured was confirmed before detecting, and was known, with the numerical value of twice detection respectively with two said definite values contrasts; If the numerical value that detects is identical with determined value, just explain that blood gas analyzer is accurately, can continue to use; If the numerical value that detects is different with determined value, just explain that blood gas analyzer is inaccurate, need the adjustment blood gas analyzer.In the said storer that the data of first reagent, second reagent and sample detection are all preserved, the data that the user obtains according to test sample are judged and are analyzed, and carry out subsequent operation.Therefore in the present technique scheme, only utilize liquid,,, make things convenient for the transportation of instrument and move without gas cylinder without gas; Only utilize liquid, use also very simply, avoided needing decompression, insulation, humidifying trouble caused because of using gases; Avoid having reduced the probability that breaks down, thereby improve the reliability of instrument because of liquid gets into the fault that gas circuit produces.
Further, in the said needle-valve main channel is arranged, first thief hatch and second thief hatch are arranged on the main channel, said first thief hatch connects first passage, and said second thief hatch connects second channel; First reagent, second reagent, protein liquid removal and cleaning fluid get into the main channel in the needle-valve through first passage, and first thief hatch in the main channel gets into follow-up flow channel tube; When cleaning stream, the cleaning fluid that gets into the main channel is divided into two parts, and a part gets into flow channel tube from first thief hatch; Clean in the sales kit (SK) and follow-up stream, get into waste fluid bag at last, another part gets into second channel from second thief hatch; Extract out by the 3rd pump housing, get into waste fluid bag at last, the setting of each passage in the needle-valve; The needs that satisfied blood gas analyzer calibration, deproteinized, sampling and cleaned stream, easy to use, avoid getting into the fault that gas circuit produces because of liquid; Reduce the probability that breaks down, thereby improved the reliability of instrument.
Further; Said first passage connects detector of liquid; Be convenient to first reagent, second reagent, protein liquid removal and cleaning fluid and get into the main channel in the needle-valve through flow channel tube, said second channel connects the 3rd pump housing through flow channel tube, is convenient to cleaning fluid smoothly through the 3rd pump housing; Get into waste fluid bag, thus the convenient stream that cleans.
Further, said blood gas analyzer also comprises the sample collecting device, and this sample collecting device inserts second thief hatch; Sampling needle inserts in the sample collecting device through the main channel; Sample in the draw samples collector, after extraction finished, sampling needle was extracted; The sample collecting device is also extracted from second thief hatch, and is easy to use.
Further, sampling needle one end inserts in the sample collecting device through the main channel, detecting device before the other end connects; This sampling needle front end has pin hole; Under the effect of first pump housing, the examination sampling needle is extracted the sample in the sample collecting device out through the pin hole of sidewall, and sample gets into said test membrane pipe through preceding detecting device; Be convenient to detect, easy to use.
The present invention also provides a kind of method of application of blood gas analyzer, comprises the steps:
S1, confirm first standard value: open the 6th solenoid valve, first pump housing extracts first reagent in the first reagent bag through flow channel tube; When detector of liquid detects first reagent, close the 6th solenoid valve, open the 3rd solenoid valve, first reagent gets into and detects in the film pipe; When the back detecting device detected first reagent, first pump housing stopped operating, and closes the 3rd solenoid valve, and electrode begins test, and the data of test are kept in the storer, as first standard value; Open the 3rd solenoid valve then, first pump housing is with in the first reagent suction waste fluid bag in the stream;
S2, confirm second standard value: open the 5th solenoid valve, first pump housing extracts second reagent in the second reagent bag through flow channel tube; When detector of liquid detects second reagent, close the 5th solenoid valve, open the 3rd solenoid valve, second reagent gets into and detects in the film pipe; When the back detecting device detected second reagent, first pump housing stopped operating, and electrode begins test, and the data of test are kept in the storer, as second standard value; Open the 3rd solenoid valve then, first pump housing is with in the second reagent suction waste fluid bag in the stream;
S3, deproteinized: open the 4th solenoid valve, first pump housing extracts the protein liquid removal in the 3rd reagent bag through flow channel tube; When detector of liquid detected protein liquid removal, said first pump housing continued to be rotated counterclockwise, and closes the 4th solenoid valve then, opens the 3rd solenoid valve, and protein liquid removal gets into and detects in the film pipe; When the back detecting device detected protein liquid removal, first pump housing was rotated further, and when protein liquid removal begins to get into waste fluid bag, closes the 3rd solenoid valve, and blood protein residual in protein liquid removal and the stream is fully reacted.At last, first pump housing rotates, in the deproteinized waste liquid suction waste fluid bag in the flow channel tube;
S4, sampling: sampling needle inserts in the sample, and first pump housing rotates counterclockwise, draw samples; Sampling needle is extracted out from sample then, and first pump housing is extracted into the sample in the stream and detects in the film pipe through preceding detecting device, and sample detecting device before out-of-date constantly detects; After sample passes through preceding detecting device; First pump housing stops operating, and the electrode pair sample detects, and testing result is kept in the storer; First pump rotates, and the sample in the stream is arranged in the waste fluid bag; And
S5, clean stream: the first solenoid valve pause switch, open second solenoid valve, second pump housing is extracted into the main channel in the needle-valve through flow channel tube with the cleaning fluid in the 4th reagent bag; First solenoid valve often changes into to be opened, and closes second solenoid valve, and first pump housing is evacuated to waste fluid bag through first thief hatch, sales kit (SK) successively with a part of cleaning fluid that second pump housing pushes the main channel; Simultaneously the 3rd pump housing is shifted second pump housing onto in the main channel of needle-valve and another part cleaning fluid of overflowing to second thief hatch is evacuated to waste fluid bag; Second pump housing rotates continuously, and till detector of liquid detected less than cleaning fluid, first pump housing and the 3rd pump housing stopped operating after the cleaning fluid in the stream all is extracted into waste fluid bag.
Wherein, in the first reagent bag first reagent is housed, in the second reagent bag second reagent is housed, in the 3rd reagent bag protein liquid removal is housed, in the 4th reagent bag cleaning fluid is housed; The 3rd solenoid valve, the 4th solenoid valve, the 5th solenoid valve and the 6th solenoid valve are set up in parallel; Connect the flow channel tube between second pump housing and the detector of liquid in order successively; Said the 3rd solenoid valve is near said second pump housing, and solenoid valve is swift in response, and switch is flexible; Automatically control is used easily blood gas analyzer.In first reagent and second reagent, the numerical value of target to be measured was confirmed before detecting, is known; The numerical value of twice detection is contrasted with two said definite values respectively,, just explain that blood gas analyzer is accurately if the numerical value that detects is identical with determined value; Can continue to use; If the numerical value that detects is different with determined value, just explain that blood gas analyzer is inaccurate, need the adjustment blood gas analyzer.In the said storer that the data of first reagent, second reagent and sample detection are all preserved, the data that the user obtains according to test sample are judged and are analyzed, and carry out subsequent operation.Therefore in the present technique scheme, only utilize liquid,,, make things convenient for the transportation of instrument and move without gas cylinder without gas; Only utilize liquid, use also very simply, avoided needing decompression, insulation, humidifying trouble caused because of using gases; Avoid having reduced the probability that breaks down, thereby improve the reliability of instrument because of liquid gets into the fault that gas circuit produces.
Further, among the said step S1, the pin hole of sampling needle is positioned at first thief hatch, and first reagent first passage of flowing through gets into the sampling needle from pin hole; Among the said step S2, the pin hole of sampling needle is positioned at first thief hatch, and second reagent first passage of flowing through gets into the sampling needle from pin hole.Among step S1 and the S2, sampling needle is positioned at first thief hatch, and the liquid of being convenient to get into first thief hatch gets into the follow-up stream from sampling needle; Easy to use; Simultaneously, only detect, avoided getting into the fault that gas circuit produces because of liquid with liquid; Reduce the probability that breaks down, thereby improved the reliability of instrument.
Further, among the step S4, the bottleneck of sample collecting device inserts in second thief hatch; Sampling needle passes the main channel and inserts in the sample collecting device, through the sample in the pin hole draw samples collector, extracted sample after; Extract sampling needle out, carry out subsequent operation, easy to use.
Beneficial effect of the present invention: replace the method for gas of the prior art and liquid mixing calibration through liquid calibration, uses more conveniently, avoid the fault that produces because of liquid entering gas circuit, reduced the probability that breaks down, thus the reliability of raising instrument.
Description of drawings
Fig. 1 is the structural representation of an embodiment of the present invention;
Fig. 2 is the longitudinal sectional drawing of needle-valve in the one embodiment of the invention;
Fig. 3 be in the one embodiment of the invention when sampling needle-valve longitudinal sectional drawing.
Mark among the figure: 1-sampling stand; The 101-needle-valve; The 102-main channel; The 103-first passage; The 104-second channel; 105-first thief hatch; 106-second thief hatch; The 107-sampling needle; The 108-pin hole; 109-sample collecting device; The 2-sales kit (SK); Detecting device before the 201-; 202-detects the film pipe; Detecting device behind the 203-; The 204-electrode; The 205-storer; The 3-flow channel tube; 4-first pump housing; 5-second pump housing; 6-the 3rd pump housing; The 7-waste fluid bag; 8-first solenoid valve; 9-second solenoid valve; 10-the 4th reagent bag; 11-the 3rd solenoid valve; 12-the 4th solenoid valve; 13-the 3rd reagent bag; 14-the 5th solenoid valve; The 15-second reagent bag; 16-the 6th solenoid valve; The 17-first reagent bag; The 18-detector of liquid.
Embodiment
Below in conjunction with accompanying drawing, more excellent embodiment of the present invention is done further detailed description:
Embodiment 1; Referring to Fig. 1; A kind of blood gas analyzer comprises: place sampling stand 1 needle-valve 101, connect said needle-valve 101 sales kit (SK) 2, connect said sales kit (SK) 2 first pump housing 4, connect said first pump housing 4 waste fluid bag 7, connect said needle-valve 101 and second pump housing 5 detector of liquid 18, through second solenoid valve 9 is connected said second pump housing 5 the 4th reagent bag 10, connect said detector of liquid 18 the 3rd solenoid valve 11, connect this second pump housing 5 first solenoid valve 8, through the 6th solenoid valve 16 connect said detector of liquid 18 the first reagent bag 17, through the 5th solenoid valve 14 connect said detector of liquid 18 the second reagent bag 15, through the said detector of liquid 18 of the 4th solenoid valve 12 connections the 3rd reagent bag 13 and second pump housing 5 of connection needle-valve 101 and waste fluid bag 7; In the sales kit (SK) 2, an end of preceding detecting device 201 connects needle-valve 101, and the other end is joint detection film pipe 202 and back detecting device 203 successively, and back detecting device 203 connects first pump housing 4; All passing through flow channel tube 3 between aforementioned each parts connects; Storer 205 is through electrode 204 joint detection film pipes; In above-mentioned each reagent bag different liquid is housed, on first solenoid valve 8 and the 3rd solenoid valve 11 air intake opening is arranged all, when detector of liquid 18 detects liquid; The closed electromagnetic valve of having opened that is used to extract liquid; The 3rd solenoid valve 11 is opened, and air substitutes liquid and gets into flow channel tube 3, in the balance flow channel tube 3 with the air pressure of space outerpace; Make the liquid in the flow channel tube 3 get into 202 detections of detection film pipe smoothly, practiced thrift liquid simultaneously; When second solenoid valve 9 is opened the extraction cleaning fluid, open first solenoid valve 8, air is got in the flow channel tube 3, air and cleaning fluid mix, and in flow channel tube 3, form the cleaning fluid of segmentation, clean more thorough.
Wherein, The 3rd solenoid valve 11, the 4th solenoid valve 12, the 5th solenoid valve 14 and the 6th solenoid valve 16 are set up in parallel, and connect the flow channel tube 3 between second pump housing 5 and the detector of liquid 18 in order successively, and said the 3rd solenoid valve 11 is near said second pump housing 5; Solenoid valve is swift in response; Switch is flexible, and control is automatically used easily blood gas analyzer.In the first reagent bag 17 first reagent is arranged, in the second reagent bag 15 second reagent is arranged, in first reagent and second reagent; The numerical value of target to be measured was confirmed before detecting, and was known, with the numerical value of twice detection respectively with two said definite values contrasts; If the numerical value that detects is identical with determined value, just explain that blood gas analyzer is accurately, can continue to use; If the numerical value that detects is different with determined value, just explain that blood gas analyzer is inaccurate, need the adjustment blood gas analyzer.In the said storer 205 that the data of first reagent, second reagent and sample detection are all preserved, the data that the user obtains according to test sample are judged and are analyzed, and carry out subsequent operation.Therefore in the present technique scheme, only utilize liquid,,, make things convenient for the transportation of instrument and move without gas cylinder without gas; Only utilize liquid, use also very simply, avoided needing decompression, insulation, humidifying trouble caused because of using gases; Avoid having reduced the probability that breaks down, thereby improve the reliability of instrument because of liquid gets into the fault that gas circuit produces.
Embodiment 2, referring to Fig. 2, main channel 102 arranged in the needle-valve 101, and first thief hatch 105 and second thief hatch 106 are arranged on the main channel 102, and said first thief hatch 105 connects first passage 103, and said second thief hatch 106 connects second channel 104; The main channel 102 that first reagent, second reagent, protein liquid removal and cleaning fluid get in the needle-valve 101 through first passage 103,102 first thief hatch 105 gets into follow-up flow channel tube 3 in the main channel; When cleaning stream, the cleaning fluid that gets into main channel 102 is divided into two parts, and a part gets into flow channel tube 3 from first thief hatch 105; Clean in the sales kit (SK) 2 and follow-up stream, get into waste fluid bag 7 at last, another part gets into second channel 104 from second thief hatch 106; Extract out by the 3rd pump housing 6, get into waste fluid bag 7 at last, the setting of each passage in the needle-valve 101; The needs that satisfied blood gas analyzer calibration, deproteinized, sampling and cleaned stream, easy to use, avoid getting into the fault that gas circuit produces because of liquid; Reduce the probability that breaks down, thereby improved the reliability of instrument.
Embodiment 3; Referring to Fig. 1 and Fig. 2, first passage 103 connects detector of liquid 18, is convenient to the main channel 102 that first reagent, second reagent, protein liquid removal and cleaning fluid get in the needle-valve 101 through flow channel tube 3; Said second channel 104 connects the 3rd pump housing 6 through flow channel tube 3; Be convenient to cleaning fluid smoothly through the 3rd pump housing 6, get into waste fluid bag 7, thus the convenient stream that cleans.
Embodiment 4, and referring to Fig. 3, blood gas analyzer also comprises sample collecting device 109; This sample collecting device 109 inserts second thief hatch 106, and sampling needle 107 inserts in the sample collecting device 109 through main channel 102, the sample in the draw samples collector 109; After extraction finishes; Sampling needle 107 is extracted, and sample collecting device 109 is also extracted from second thief hatch 106, and is easy to use.
Embodiment 5, and referring to Fig. 1 and Fig. 3, an end of sampling needle 107 inserts in the sample collecting device through main channel 102; Detecting device 201 before the other end connects, these sampling needle 107 front ends have pin hole 108, under the effect of first pump housing 4; Examination sampling needle 107 is extracted the sample in the sample collecting device out through the pin hole 108 of sidewall; Sample gets into said test membrane pipe through preceding detecting device 201, is convenient to detect, and is easy to use.
Embodiment 6, and referring to Fig. 1 to Fig. 3, a kind of method of application of blood gas analyzer comprises the steps:
S1, confirm first standard value: open the 6th solenoid valve 16, pin hole 108 is aimed at first thief hatch, 105, the first pump housings 4 and is rotated counterclockwise, and extracts first reagent in the first reagent bag 17.When detector of liquid 18 detects first reagent; Close the 6th solenoid valve 16, open the 3rd solenoid valve 11, gas gets in the flow channel tube 3 through the air intake opening on the 3rd solenoid valve 11; First pump housing 4 continues to rotate counterclockwise; When the back detecting device 203 in the sales kit (SK) 2 detected first reagent, first pump housing 4 stopped operating, and the 3rd solenoid valve 11 cuts out.At this moment, be full of first reagent in sales kit (SK) 2 overall flow paths, electrode 204 begins test, and the data of test are kept in the storer, as first standard value.The 3rd solenoid valve 11 is opened then, and first pump housing 4 rotates counterclockwise in the first reagent suction waste fluid bag 7 in the stream;
S2, confirm second standard value: open the 5th solenoid valve 14, pin hole 108 is aimed at second thief hatch, 106, the first pump housings 41 and is rotated counterclockwise, and extracts second reagent in the second reagent bag 15.When detector of liquid 18 detects second reagent; The 5th solenoid valve 14 cuts out; The 3rd solenoid valve 11 is opened, and gas gets in the flow channel tube 3 through the air intake opening on the 3rd solenoid valve 11, and first pump housing 4 continues to rotate counterclockwise; When the back detecting device 203 in the sales kit (SK) 2 detected second reagent, first pump housing 4 stopped operating.At this moment, be full of second reagent in sales kit (SK) 2 overall flow paths, electrode 204 begins test, and the data of test are kept in the storer, as second standard value.The 3rd solenoid valve 11 is opened, and first pump housing 4 rotates counterclockwise, in the second reagent suction waste fluid bag 7 in the stream;
S3, deproteinized: open the 4th solenoid valve 12, pin hole 108 is aimed at first thief hatch, 105, the first pump housings 4 and is rotated counterclockwise, and extracts the protein liquid removal in the 3rd reagent bag 13.When detector of liquid 18 detected protein liquid removal, said first pump housing 4 continued to be rotated counterclockwise, and closes the 4th solenoid valve 12 then; Open the 3rd solenoid valve 11, the air intake opening on air the 3rd solenoid valve 11 gets in the flow channel tube 3, and first pump housing 4 continues to rotate counterclockwise; When the back detecting device 203 in the sales kit (SK) 2 detects protein liquid removal; First pump housing 4 continues to rotate counterclockwise, and when having protein liquid removal to get into waste fluid bag 7, closes the 3rd solenoid valve 11.At this moment, all be full of protein liquid removal in the overall flow paths, protein liquid removal stopped in stream 3 minutes, and blood protein residual in protein liquid removal and the stream is fully reacted.At last, first pump housing 4 rotates counterclockwise, in the deproteinized waste liquid suction waste fluid bag 7 in the flow channel tube 3;
S4, sampling: sampling needle 107 inserts in the sample, and first pump housing 4 rotates counterclockwise draw samples; This first pump housing 4 continues to rotate counterclockwise 4 circles, and sampling needle 107 is extracted out from sample, pin hole 108 and atmosphere; First pump housing 4 continues to rotate counterclockwise, and in the detecting device 201, first pump housing 4 continued to twitch sample and travels forward before the sample in the stream was extracted into; Preceding detecting device 201 constantly detects, and when detecting sample through behind the preceding detecting device 201, first pump housing 4 stops operating; Sample was full of and detected film pipe 202 this moment, and 204 pairs of samples of electrode detect, and testing result is kept in the storer 205.After detect finishing, first pump housing 4 rotates counterclockwise, and the sample in the stream is arranged in the waste fluid bag 7; And
S5, clean stream: open second solenoid valve 9, sampling needle 107 moves on to first thief hatch 105 in the needle-valve 101.Second pump housing 5 rotates counterclockwise the cleaning fluid that extracts in the 4th reagent bag 10; First solenoid valve, 8 pause switches; In the liquid that second pump extracts, form the gas-liquid segmentation, second pump housing 5 rotates continuously, in stream, pushes the liquid of gas-liquid segmentation to needle-valve 101; When first solenoid valve 8 through open close the gas-liquid segmentation that produces 9 sections after; First solenoid valve 8 often changes into to be opened, and closes the gas-liquid mixed flow direction needle-valve 101 that second solenoid valve, 9, the second pump housings 5 promote in the stream; When the detector of liquid in the stream 18 detected cleaning fluid, first pump housing 4 rotated counterclockwise the cleaning fluid that second pump housing 5 is pushed a part of gas-liquid segmentation of valve pocket and is evacuated to waste fluid bag 7 to clean first thief hatch 105 to the sales kit (SK), 2 part streams through first thief hatch 105, sales kit (SK) 2 successively; Simultaneously the 3rd pump housing 6 clockwise rotates, and second pump housing 5 is shifted onto in the main channel 102 of needle-valve 101 and the liquid that overflows to another part gas-liquid segmentation of second thief hatch 106 is evacuated to waste fluid bag 7, to clean the main channel 102 of needle-valve 101.Second pump housing 5 promotes gas-liquid segmentation liquid inserting needle valve 101 continuously, and when detector of liquid 18 detected less than cleaning fluid, second pump housing 5 stopped operating, and first pump housing 4 and the 3rd pump housing 6 stop operating after the cleaning fluid in the stream all is extracted into waste fluid bag 7.
Among the step S4, the bottleneck of sample collecting device 109 inserts in second thief hatch 106, and sampling needle 107 passes main channel 102 and inserts in the sample collecting device 109; Through the sample in the pin hole 108 draw samples collectors 109, extracted sample after, extract sampling needle 107 out; Carry out subsequent operation, easy to use.
In first reagent and second reagent, the numerical value of target to be measured was confirmed before detecting, is known; The numerical value of twice detection is contrasted with two said definite values respectively,, just explain that blood gas analyzer is accurately if the numerical value that detects is identical with determined value; Can continue to use; If the numerical value that detects is different with determined value, just explain that blood gas analyzer is inaccurate, need the adjustment blood gas analyzer.In the said storer 205 that the data of first reagent, second reagent and sample detection are all preserved, the data that the user obtains according to test sample are judged and are analyzed, and carry out subsequent operation.The foregoing description replaces the method for gas of the prior art and liquid mixing calibration through liquid calibration, uses more conveniently, avoids the fault that produces because of liquid entering gas circuit, has reduced the probability that breaks down, thus the reliability of raising instrument.
Above content is to combine concrete preferred implementation to the further explain that the present invention did, and can not assert that practical implementation of the present invention is confined to these explanations.For the those of ordinary skill of technical field under the present invention, under the prerequisite that does not break away from the present invention's design, can also make some simple deduction or replace, all should be regarded as belonging to protection scope of the present invention.

Claims (9)

1. blood gas analyzer; It is characterized in that, comprising: place sampling stand needle-valve, connect said needle-valve sales kit (SK), connect said sales kit (SK) first pump housing, connect said first pump housing waste fluid bag, connect said needle-valve and second pump housing detector of liquid, through second solenoid valve be connected said second pump housing the 4th reagent bag, connect said detector of liquid the 3rd solenoid valve, connect this second pump housing first solenoid valve, through the 6th solenoid valve connect said detector of liquid the first reagent bag, through the 5th solenoid valve connect said detector of liquid the second reagent bag, through the 4th solenoid valve connect said detector of liquid the 3rd reagent bag and second pump housing of connection needle-valve and waste fluid bag; In the sales kit (SK), an end of preceding detecting device connects needle-valve, and the other end is joint detection film pipe and back detecting device successively, and back detecting device connects first pump housing; All passing through flow channel tube between aforementioned each parts connects; Storer is through electrode joint detection film pipe; On first solenoid valve and second solenoid valve air intake opening is arranged all.
2. blood gas analyzer according to claim 1; It is characterized in that: main channel, first passage and second channel are arranged in the said needle-valve; First thief hatch and second thief hatch are arranged on the main channel, and said first thief hatch connects first passage, and said second thief hatch connects second channel.
3. blood gas analyzer according to claim 2 is characterized in that: said first passage connects detector of liquid, and said second channel connects the 3rd pump housing through flow channel tube.
4. blood gas analyzer according to claim 3 is characterized in that: also comprise the sample collecting device, it is inner that this sample collecting device inserts second thief hatch.
5. blood gas analyzer according to claim 4 is characterized in that: in the said sample collecting device sample is housed.
6. blood gas analyzer according to claim 5 is characterized in that: sampling needle one end inserts in the sample collecting device through the main channel, and detecting device before the other end connects has pin hole on this sampling needle.
7. according to the method for application of any described blood gas analyzer of claim 1 to 6, its characteristic in, comprise the steps:
S1, confirm first standard value: open the 6th solenoid valve, first pump housing extracts first reagent in the first reagent bag through flow channel tube; When detector of liquid detects first reagent, close the 6th solenoid valve, open the 3rd solenoid valve, first reagent gets into and detects in the film pipe; When the back detecting device detected first reagent, first pump housing stopped operating, and closes the 3rd solenoid valve, and electrode begins test, and the data of test are kept in the storer, as first standard value; Open the 3rd solenoid valve then, first pump housing is with in the first reagent suction waste fluid bag in the stream;
S2, confirm second standard value: open the 5th solenoid valve, first pump housing extracts second reagent in the second reagent bag through flow channel tube; When detector of liquid detects second reagent, close the 5th solenoid valve, open the 3rd solenoid valve, second reagent gets into and detects in the film pipe; When the back detecting device detected second reagent, first pump housing stopped operating, and electrode begins test, and the data of test are kept in the storer, as second standard value; Open the 3rd solenoid valve then, first pump housing is with in the second reagent suction waste fluid bag in the stream;
S3, deproteinized: open the 4th solenoid valve, first pump housing extracts the protein liquid removal in the 3rd reagent bag through flow channel tube; When detector of liquid detected protein liquid removal, said first pump housing continued to be rotated counterclockwise, and closes the 4th solenoid valve then, opens the 3rd solenoid valve, and protein liquid removal gets into and detects in the film pipe; When the back detecting device detected protein liquid removal, first pump housing was rotated further, and when protein liquid removal begins to get into waste fluid bag, closes the 3rd solenoid valve, and blood protein residual in protein liquid removal and the stream is fully reacted; At last, first pump housing rotates, in the deproteinized waste liquid suction waste fluid bag in the flow channel tube;
S4, sampling: sampling needle inserts in the sample, and first pump housing rotates counterclockwise, draw samples; Sampling needle is extracted out from sample then, and first pump housing is extracted into the sample in the stream and detects in the film pipe through preceding detecting device, and sample detecting device before out-of-date constantly detects; After sample passes through preceding detecting device; First pump housing stops operating, and the electrode pair sample detects, and testing result is kept in the storer; First pump rotates, and the sample in the stream is arranged in the waste fluid bag; And
S5, clean stream: the first solenoid valve pause switch, open second solenoid valve, second pump housing is extracted into the main channel in the needle-valve through flow channel tube with the cleaning fluid in the 4th reagent bag; First solenoid valve often changes into to be opened, and closes second solenoid valve, and first pump housing is evacuated to waste fluid bag through first thief hatch, sales kit (SK) successively with a part of cleaning fluid that second pump housing pushes the main channel; Simultaneously the 3rd pump housing is shifted second pump housing onto in the main channel of needle-valve and another part cleaning fluid of overflowing to second thief hatch is evacuated to waste fluid bag; Second pump housing rotates continuously, and till detector of liquid detected less than cleaning fluid, first pump housing and the 3rd pump housing stopped operating after the cleaning fluid in the stream all is extracted into waste fluid bag.
8. the method for application of blood gas analyzer according to claim 7, it is characterized in that: among the said step S1, the pin hole of sampling needle is positioned at first thief hatch, and first reagent first passage of flowing through gets into the sampling needle from pin hole; Among the said step S2, the pin hole of sampling needle is positioned at first thief hatch, and second reagent first passage of flowing through gets into the sampling needle from pin hole.
9. the method for application of blood gas analyzer according to claim 8; It is characterized in that: among the step S4; The bottleneck of sample collecting device inserts in second thief hatch, and sampling needle passes the main channel and inserts in the sample collecting device, through the sample in the pin hole draw samples collector.
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