CN102727622A - Traditional Chinese medicinal enema for treating chronic colitis - Google Patents
Traditional Chinese medicinal enema for treating chronic colitis Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicinal enema for treating chronic colitis. According to the traditional Chinese medicinal science, the pathogenesis of chronic colitis is mainly due to syndromes of dampness-heat due to spleen deficiency and qi depression to blood stasis, especially develops in colonic mucosa and submucosa inflammation and ulcer changes, and is characterized by stomachache, diarrhea, mucous bloody stool and tenesmus in clinic. Therefore, traditional Chinese medicines, which have effects of clearing heat, drying damp, diminishing swelling, promoting granulation, removing pattogenic heat from the blood and toxic material from the body, relieving diarrhea, diminishing inflammation, resolving tetany and relieving pain, including traditional Chinese medicinal Swamp Mahogany Leaf, champion dutchmanspipe root, mongolian oak bark, Scutellaria baicalensis, cortex fraxini, Cape jasmine, Rhizoma Atractylodis Macrocephalae, licorice root, Codonopsis pilosula, cortex albiziae, fruits of Litsea rubescens, cortex cinnamomi and hurricane lamp, are selected to be made into the enema. Through clinical tests of our public health centre, the total effective rate of the enema reaches 96.3% and it is obviously better than a control group. In addition, patients have no adverse reaction after taking the medicine. Therefore, the medicine is worth of clinical popularization and application.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of herbal enema agent of treating chronic colitis.
Background technology
Chronic colitis is Gastroenterology dept.'s commonly encountered diseases, frequently-occurring disease, the many protracteds course of disease of the state of an illness, and outbreak repeatedly often has symptoms such as left lower quadrant is painful, diarrhoea.Because etiology unknown, the course of disease is long, and outbreak repeatedly is so also very thorny in treatment.Part patient is because intestinal damage under intestinal inflammation stimulates, reparation repeatedly finally possibly cause the generation of tumor; The western medical treatment method is a lot of at present, but curative effect is not satisfied, and relapse rate is also high; Have a strong impact on patient's body health and quality of life.
Summary of the invention
The purpose of this invention is to provide a kind of herbal enema agent of treating chronic colitis.The traditional Chinese medical science thinks that its pathogenesis is main with insufficiency of the spleen damp and hot, qi depression to blood stasis, and special sending out in mucous membrane of colon, submucosal inflammation ulcer changes.Clinical is characteristics with stomachache, diarrhoea, mucosanguineous feces, tenesmus.Traditional Chinese medical science heat clearing and damp drying, detumescence and promoting granulation, removing pathogenic heat from blood and toxic substance from the body, antidiarrheal antiinflammatory, relieving spasm to stop pain, improve local blood circulation and metabolism, enhancing intestinal immune function, promote the purpose of ulcer healing.
The objective of the invention is to realize that through following technical scheme the herbal enema agent of this treatment chronic colitis is processed by following parts by weight of Chinese traditional medicine: Folium Eucalypti Robustae 12-15 part, Radix Aristolochiae championii 5-7 part, Cortex Querci Mongolicae 10-12 part, Radix Scutellariae 15-20 part, Cortex Fraxini 15-20 part, Fructus Gardeniae 15-20 part, Rhizoma Atractylodis Macrocephalae 12-15 part, Radix Glycyrrhizae 5-7 part, Radix Codonopsis 12-15 part, Cortex Albiziae 12-15 part, Fructus litseae rubescentis 12-15 part, Cortex Cinnamomi 14-16 part, windproof 8-10 part.
Preferably, 14 parts of Folium Eucalypti Robustaes, 6 parts of Radix Aristolochiae championiis, 11 parts of Cortex Querci Mongolicaes, 18 parts of Radix Scutellariaes, 18 parts of Cortex Fraxinis, 18 parts of Fructus Gardeniaes, 14 parts of the Rhizoma Atractylodis Macrocephalaes, 6 parts in Radix Glycyrrhizae, 13 parts of Radix Codonopsis, 13 parts of Cortex Albiziaes, 13 parts of Fructus litseae rubescentis, 15 parts of Cortex Cinnamomis, windproof 9 parts.
Method for preparing: it is subsequent use to about 200ml that medicine-feeding is added decocting.
In the side: Folium Eucalypti Robustae: heat-clearing and toxic substances removing, convergence granulation promoting, dispelling wind for relieving itching, control enteritis.
Radix Aristolochiae championii: heat-clearing and toxic substances removing, control gastroenteritis, furuncle swells and ache.
Cortex Querci Mongolicae: have clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, the effect of astringing to arrest diarrhea.
Radix Scutellariae: return lung, gallbladder, stomach, large intestine channel; Heat clearing and damp drying, eliminating fire and detoxication.
Cortex Fraxini: go into Liver Channel, gallbladder meridian, large intestine channel, heat clearing and damp drying, the detoxifcation relieving convulsion, leukorrhagia stopping makes eye bright.
Fructus Gardeniae: GUIXIN, lung, stomach, tri-jiao channel; Clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, dampness removing.
The Rhizoma Atractylodis Macrocephalae: return spleen, stomach warp; Air making-up and spleen enlivening, dampness diuretic, hidroschesis.
Radix Glycyrrhizae: GUIXIN, spleen, lung, stomach warp; Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing is alleviated pain relieving.
Radix Codonopsis: return spleen, lung meridian; Invigorating the spleen and replenishing QI is promoted the production of body fluid and is nourished blood.
Cortex Albiziae: GUIXIN, Liver Channel; The resolving depression of calming the nerves, promoting blood circulation and detumescence.
Fructus litseae rubescentis: go into spleen, stomach two warps; Promoting the flow of QI in the collateral by warming the meridian, expelling wind and cold, relieving dyspepsia is controlled gastroenteritis.
Cortex Cinnamomi: return kidney, spleen, the heart, Liver Channel; It is supporing yang to mend fire, dispersing cold for relieving pain, promoting the flow of QI-blood by warming the meridian.
Windproof: as to return bladder, liver, spleen channel; Expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic.
Clinical data
1, the selected case of physical data is my out-patient of institute 160 examples of in December, 2008 to 2009 year June, is divided into treatment at random by the prescription on individual diagnosis order and organizes 80 examples, male 44 examples, women 36 examples, 21～76 years old age, average 42.42 ± 12.53 years old; Course of disease March to 16 year, average 9.26 ± 3.65 years.Matched group 80 examples, male 40 examples, women 40 examples, 19～75 years old age, average 43.53 ± 13.01 years old, the course of disease 2 months to 19 years, average 10.32 ± 4.04 years.Clinical symptoms: 90 examples of suffering from diarrhoea, mucopurulent bloody stool 60 examples, 38 examples of suffering from abdominal pain, tenesmus 32 examples.Diseased region proctitis 52 examples, proctosigmoiditis 56 examples, pancolitis 12 examples.Two groups of patients equal no difference of science of statistics (P＞0.05) aspect inflammation degree and the scope under age, sex, the course of disease, clinical manifestation and colonoscope.
2, diagnostic criteria clinical manifestation: discontinuity abdominal part dull pain, abdominal distention, stomachache etc., times of defecation increases, the anus tenesmus.During the chronic colitis acute attack, visible hyperpyrexia, abdominal colic, nausea and vomiting, stool are urgent, the patient is chronic consumption state, lustreless complexion, lassitude, limbs fatigue.Enteroscopy: see that slightly intestinal mucosa is congested, edema, be dispersed in little petechia.The diseased region intestinal mucosa is tender and musical, and easy hemorrhage, pathological changes is confined to rectum or sigmoid colon position more; The moderate extent of disease is extensive, and petechia and aphtha are arranged, and often there is secretions on the surface of ulcer; Severe bleeding point is many and comparatively intensive, is fused into lamellar hemorrhage and ulcer or erosion each other, except that rectum and sigmoid colon, also can involve each position of total colectomy.
3, Therapeutic Method treatment group is taken herbal enema agent of the present invention: Folium Eucalypti Robustae 14g, Radix Aristolochiae championii 6g, Cortex Querci Mongolicae 11g, Radix Scutellariae 18g, Cortex Fraxini 18g, Fructus Gardeniae 18g, Rhizoma Atractylodis Macrocephalae 14g, Radix Glycyrrhizae 6g, Radix Codonopsis 13g, Cortex Albiziae 13g, Fructus litseae rubescentis 13g, Cortex Cinnamomi 15g, windproof 9g.Medicine-feeding is added decocting to about 200ml, retention enema.Method: according to the state of an illness, get above-mentioned enema 70～90ml retention enema, 2～3 times/d, 20min is adhered in each requirement at least at every turn, and the coloclysis time, fluid temperature and human body temperature were adapted to suitable to be good sooner or later.Matched group is got gentamycin 160,000 u, dexamethasone 5mg, and 2% lignocaine 5ml adds normal saline 250ml, use with the quadrat method retention enema, every day 1 time, two groups equal 10 days be 1 course of treatment.
4, curative effect determinate standard recovery from illness: clinical symptoms, sign disappear, and the enteroscopy intestinal mucosal lesion recovers normal or leaves over cicatrix; Produce effects: clinical symptoms, sign disappear basically, and intestinal mucosal lesion only has mild inflammation to change; Take a turn for the better: clinical symptoms, sign alleviate to some extent, and the intestinal mucosal lesion degree alleviates to some extent; Invalid: clinical symptoms, sign do not have the intestinal mucosal lesion of alleviating degree no change or increase the weight of.
5, the therapeutic outcome treatment is added up curative effect after two courses of treatment.80 examples are organized in treatment, wherein cure 50 examples (63.0%), produce effects 20 examples (25.0%%), and 7 examples that take a turn for the better (8.8%), invalid 3 examples (3.8%), effective percentage reaches 96.3%; Matched group is cured 20 examples (25.0%), produce effects 24 examples (30.0%), and effective 20 examples (25.0%), invalid 16 examples (20%) total effective rate reaches 80%.Two groups of cure rates, total effective rates have significant difference (P＜0.05).
Herbal drug enema in treatment ulcerative colitis relieve clinical symptoms is very fast, and curative effect is superior to the western medicine group.Untoward reaction: routine 1～2 week of patient's medications of matched group 9 back occur feeling sick, vomiting, inappetence, 5 examples occur dizzy.Give anti symptom treatment, the back of continuing to take medicine disappears.Treatment group and all the other patients do not have obvious adverse reaction.
Model case patient Liu, the man, 65 years old, the peasant, because of paroxysmal abdominal pain, mucosanguineous feces, nearly 3 months of tenesmus and come my institute to go to a doctor; Check stool routine examination erythrocyte ++ ++, pus cell ++, antibacterial culturing does not have the pathogenic bacterium growth, sigmoidoscopy: nodus hemorrhoidalis intestinal mucosa congestion and edema, and there is fibrin to adhere to, there is volume to be dispersed in the intensive little petechia in blocks of part, and has aphtha to form.Examine and be chronic ulcerative colitis, use above-described herbal enema agent retention enema, check intestinal mirror is not seen petechia and ulcer surface after 1 month, does not follow up a case by regular visits to recurrence in 2 years.
The specific embodiment
Embodiment one: Folium Eucalypti Robustae 14g, Radix Aristolochiae championii 6g, Cortex Querci Mongolicae 11g, Radix Scutellariae 18g, Cortex Fraxini 18g, Fructus Gardeniae 18g, Rhizoma Atractylodis Macrocephalae 14g, Radix Glycyrrhizae 6g, Radix Codonopsis 13g, Cortex Albiziae 13g, Fructus litseae rubescentis 13g, Cortex Cinnamomi 15g, windproof 9g.Medicine-feeding is added decocting to about 200ml, retention enema.Method: according to the state of an illness, get above-mentioned enema 70～90ml retention enema, 2～3 times/d, 20min is adhered in each requirement at least at every turn, and the coloclysis time, fluid temperature and human body temperature were adapted to suitable to be good sooner or later.
Embodiment two: Folium Eucalypti Robustae 12g, Radix Aristolochiae championii 5g, Cortex Querci Mongolicae 10g, Radix Scutellariae 15g, Cortex Fraxini 15g, Fructus Gardeniae 15g, Rhizoma Atractylodis Macrocephalae 12g, Radix Glycyrrhizae 5g, Radix Codonopsis 12g, Cortex Albiziae 12g, Fructus litseae rubescentis 12g, Cortex Cinnamomi 14g, windproof 8g add decocting to about 180ml, retention enema with medicine-feeding.Method: according to the state of an illness, get above-mentioned enema 70～90ml retention enema, 2～3 times/d, 20min is adhered in each requirement at least at every turn, and the coloclysis time, fluid temperature and human body temperature were adapted to suitable to be good sooner or later.
Embodiment three: Folium Eucalypti Robustae 15g, Radix Aristolochiae championii 7g, Cortex Querci Mongolicae 12g, Radix Scutellariae 20g, Cortex Fraxini 20g, Fructus Gardeniae 20g, Rhizoma Atractylodis Macrocephalae 15g, Radix Glycyrrhizae 7g, Radix Codonopsis 15g, Cortex Albiziae 15g, Fructus litseae rubescentis 15g, Cortex Cinnamomi 16g, windproof 10g.Medicine-feeding is added decocting to about 220ml, retention enema.Method: according to the state of an illness, get above-mentioned enema 70～90ml retention enema, 2～3 times/d, 20min is adhered in each requirement at least at every turn, and the coloclysis time, fluid temperature and human body temperature were adapted to suitable to be good sooner or later.
Claims (2)
1. herbal enema agent of treating chronic colitis is characterized in that this herbal enema agent processed by following parts by weight of Chinese traditional medicine: Folium Eucalypti Robustae 12-15 part, Radix Aristolochiae championii 5-7 part, Cortex Querci Mongolicae 10-12 part, Radix Scutellariae 15-20 part, Cortex Fraxini 15-20 part, Fructus Gardeniae 15-20 part, Rhizoma Atractylodis Macrocephalae 12-15 part, Radix Glycyrrhizae 5-7 part, Radix Codonopsis 12-15 part, Cortex Albiziae 12-15 part, Fructus litseae rubescentis 12-15 part, Cortex Cinnamomi 14-16 part, windproof 8-10 part.
2. a kind of herbal enema agent of treating chronic colitis according to claim 1 is characterized in that this herbal enema agent processed by following parts by weight of Chinese traditional medicine: 14 parts of Folium Eucalypti Robustaes, 6 parts of Radix Aristolochiae championiis, 11 parts of Cortex Querci Mongolicaes, 18 parts of Radix Scutellariaes, 18 parts of Cortex Fraxinis, 18 parts of Fructus Gardeniaes, 14 parts of the Rhizoma Atractylodis Macrocephalaes, 6 parts in Radix Glycyrrhizae, 13 parts of Radix Codonopsis, 13 parts of Cortex Albiziaes, 13 parts of Fructus litseae rubescentis, 15 parts of Cortex Cinnamomis, windproof 9 parts.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103330862A (en) * | 2013-07-25 | 2013-10-02 | 林盈芝 | Stomachic tea for patient care of gastroenterology department |
| CN103463608A (en) * | 2013-09-26 | 2013-12-25 | 陈永庆 | Traditional Chinese medicine for treating ulcerative colitis |
| CN105250612A (en) * | 2015-11-06 | 2016-01-20 | 刘亚辉 | Traditional Chinese medicine enema for treating ulcerative colitis |
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| CN103463608A (en) * | 2013-09-26 | 2013-12-25 | 陈永庆 | Traditional Chinese medicine for treating ulcerative colitis |
| CN103463608B (en) * | 2013-09-26 | 2015-10-21 | 陈永庆 | A kind of medicine being used for the treatment of ulcerative colitis |
| CN105250612A (en) * | 2015-11-06 | 2016-01-20 | 刘亚辉 | Traditional Chinese medicine enema for treating ulcerative colitis |
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| CN102727622B (en) | 2013-09-11 |
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