CN102727324A - Keratoprosthesis - Google Patents
Keratoprosthesis Download PDFInfo
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- CN102727324A CN102727324A CN2012102570994A CN201210257099A CN102727324A CN 102727324 A CN102727324 A CN 102727324A CN 2012102570994 A CN2012102570994 A CN 2012102570994A CN 201210257099 A CN201210257099 A CN 201210257099A CN 102727324 A CN102727324 A CN 102727324A
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- main body
- mirror post
- support
- artificial cornea
- wire netting
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Abstract
The invention relates to the field of medical treatment, and in particular relates to a keratoprosthesi. The keratoprosthesis comprises a frame and a cylindrical lens, wherein the frame is of a shape of a smaller part of a spherical surface which is cut off by a reference surface, and the center of the frame is provided with a central hole; the inner wall of the central hole is provided with internal threads; the frame comprises a main body and a metal net which is embedded in the main body; the extension direction of the metal net is consistent with the extension direction of the main body; and the outer wall of the cylindrical lens is provided with external threads which are matched with the internal threads. Compared with the prior art, according to the keratoprosthesi, the frame is designed in the way of comprising two parts of the main body and the metal net which is embedded in the main body, and because the human eye tissue and medical resin have higher compatibility, the human eye tissue can grow together with the main body, and cannot slowly push the main body to move towards the outside; but the medical resin material is crisper and lower structural strength, the structural strength of the frame can be improved through embedding the metal net into the frame, so the frame is not easy to be damaged.
Description
Technical field
The present invention relates to medical field, be specifically related to a kind of artificial cornea.
Background technology
The artificial cornea is a kind of device that substitutes people's live cornea.When people's cornea because a variety of causes damage, the succedaneum of installing in the time of can't doing the live body corneal transplantation.
It is applicable to that the optical fundus function is fair, and corneal injury can't be the patient of corneal transplantation again.Comprise: 1) athletic injury, cornea self various diseases etc. are repeatedly done corneal transplantation failure and the patient that causes the binocular failure; 2) burn because of fire burn, soda acid; Molten iron, cement burn thoroughly damages cornea, can't be the patient that loses the sight of both eyes of live body corneal transplantation again, loses the sight of both eyes 2 years-30 years patients all can use the artificial cornea is installed.
The existing manual cornea generally is made up of support and mirror post that titanium alloy is processed.Find in clinical practice that because artificial cornea's support is a metal makes relatively poor with the agreeing with property of people ocular tissue, along with the time that support is put into ophthalmic, support can be very lentamente to the eyeball external moving, even can come off and cause operative failure.
Summary of the invention
The artificial cornea that the embodiment of the invention provides can make the in-house fixed-site of support and human eye, can slowly not move.
To achieve these goals, the present invention realizes through following technical scheme: the artificial cornea, comprise support and mirror post, and to be a sphere blocked the shape of the less part in back by a plane of reference to said support, and the center of said support is provided with centre bore; The inwall of said centre bore is provided with female thread; Said support comprises medical resin material main body of processing and the wire netting that embeds said body interior; The bearing of trend of said wire netting is consistent with the bearing of trend of said main body; The outer wall of said mirror post is provided with the external screw thread that matches with said female thread.
Further, among the aforesaid artificial cornea, said mirror post is a cylindricality; Said mirror post is sphere is blocked the less part in back by the plane of reference perpendicular to said axis structure perpendicular to two sides of its axis; And one of them is to the direction protrusion away from said mirror post, and another inside to said mirror post is recessed;
When said support cooperated with said mirror post, two said lateral protrusion directions were consistent with the protrusion direction of said support.
Further, among the aforesaid artificial cornea,
To the said side of protruding away from the direction of said mirror post, its spherical diameter is 7~8mm;
And/or
To recessed said side, the inside of said mirror post, its spherical diameter is 9.5~21.5mm.
Further, among the aforesaid artificial cornea, said main body is provided with a plurality of through holes in the periphery of said centre bore.
Further, among the aforesaid artificial cornea,
The material of said main body is medical polymethyl methacrylate;
And/or
The material of said wire netting is a titanium alloy.
Further, among the aforesaid artificial cornea, the diameter of said mirror post is 2.2~3.5mm.
Further, among the aforesaid artificial cornea, the diameter projected of said main body on its sagittal plane is 7.1~8.1mm; The diameter projected of said wire netting on its sagittal plane is 7~8mm.
Further, among the aforesaid artificial cornea,
The thickness of said wire netting is 0.06~0.1mm;
And/or
The thickness of said main body is 0.35~0.45mm.
Compared with prior art; Artificial cornea of the present invention is through with support Design being the wire netting two parts that comprise main body and embedding body interior; Because the agreeing with property of people ocular tissue and medical resin is higher; Human eye can be grown in main body when being organized in growth, can slowly not promote it to external moving; But the medical resin material is more crisp, and structural strength is lower, embeds the structural strength that wire netting can improve support through portion within it, makes it not fragile.
In addition, artificial cornea provided by the present invention also has following beneficial effect:
(1) through with mirror post and centre bore through being threaded, can play the better seal effect, prevent that intraocular fluid seepage from going out;
(2) the mirror post all is designed to the part of sphere perpendicular to two sides of its axis, can forms the effect of convex lens, amplify object and also enlarge angular field of view, can also play the effect of correct vision;
(3) large diameter mirror post can provide more wide visual field scope for the patient, but also has the daily nursing difficulty simultaneously, and problems such as pathological changes take place easily; Though and the nursing of undersized mirror post easily, its field range is narrower, and effect is not very desirable.The diameter of mirror post is set to 2.2~3.5mm, and field range can be not too small in this scope, and daily nursing is also simple relatively;
(4) through on the main body of centre bore periphery, a plurality of through holes being set; Can make outside the wire netting that embeds body interior is exposed to; When human eye is organized in growth; The tissue growth that the tissue that is positioned at wire netting one side can see through wire netting and opposite side together, thereby support is fixed more firm, prevent that further it from moving; In addition, through the weight that through hole can also alleviate support is set, the sense of discomfort of people ocular tissue is alleviated;
(5) medical polymethyl methacrylate and titanium alloy all are and agreeing with property of human body material relatively preferably; Tissue is less relatively to the rejection of these two kinds of materials; Therefore use medical polymethyl methacrylate to serve as the material of main body; And the material that uses titanium alloy to serve as wire netting all can reduce the zest of artificial cornea to people ocular tissue, avoids taking place rejection;
(6) people's eyeball is a very accurate tissue, and the implantable artificial cornea more or less can damage eyeball on eyeball, so choose reasonable artificial cornea's size is very crucial; Through being 7.1~8.1mm with the diameter projected of main body on its sagittal plane, can guarantee that the artificial cornea is more convenient in use, and also lower to the influence of eyeball; And embed the structural strength that large-sized wire netting can improve support to greatest extent through inside in main body as far as possible;
(7) the thin more infringement to eyeball of support is also just few more, but cost of manufacture and implantation difficulty also can be multiplied; Through test of many times, it is all better to confirm that finally thickness is that the main body of 0.35~0.45mm and wire netting that thickness is 0.06~0.1mm are formed its each side cost performance of support.
Description of drawings
In order to be illustrated more clearly in the embodiment of the invention or technical scheme of the prior art; Below will discuss the accompanying drawing of required use in embodiment or the description of the Prior Art; Obviously, only be some embodiments of the present invention in the technical scheme that combines accompanying drawing to describe, for those of ordinary skills; Under the prerequisite of not paying creative work, can also obtain other embodiment and accompanying drawing thereof according to these accompanying drawing illustrated embodiments.
Fig. 1 is that the master of the artificial cornea's that provides of the specific embodiment of the invention support looks sketch map;
Fig. 2 is the artificial cornea's that provides of the specific embodiment of the invention a mirror post sketch map;
Fig. 3 is the artificial cornea's that provides of the specific embodiment of the invention the support and the sketch map that cooperates of mirror post.
Reference numeral: 1-centre bore, 2-main body, 3-wire netting, 4-side, 5-through hole.
The specific embodiment
Below will combine accompanying drawing that the technical scheme of various embodiments of the present invention is carried out clear, complete description, obviously, described embodiment only is a part of embodiment of the present invention, rather than whole embodiment.Based on the embodiment described in the present invention, those of ordinary skills are resulting all other embodiment under the prerequisite that does not need creative work, all in the scope that the present invention protected.
An embodiment of the invention provide a kind of artificial cornea, comprise support and mirror post, and said support is a sphere is blocked the less part in back by a plane of reference a shape; The center of said support is provided with centre bore; The inwall of said centre bore is provided with female thread; Said support comprises medical resin material main body of processing and the wire netting that embeds body interior; The bearing of trend of said wire netting is consistent with the bearing of trend of said main body; The outer wall of said mirror post is provided with the external screw thread that matches with said female thread.
Like this, because the agreeing with property of people ocular tissue and medical resin is higher, human eye can be grown in main body when being organized in growth, can slowly not promote it to external moving; But the medical resin material is more crisp, and structural strength is lower, embeds the structural strength that wire netting can improve support through portion within it, makes it not fragile.
In addition, through with mirror post and centre bore through being threaded, can play the better seal effect, prevent that intraocular fluid seepage from going out.
In each embodiment of the present invention, as preferred version, said mirror post is a cylindricality; Said mirror post is sphere is blocked the less part in back by the plane of reference perpendicular to said axis structure perpendicular to two sides of its axis; And one of them is to the direction protrusion away from said mirror post, and another inside to said mirror post is recessed;
When said support cooperated with said mirror post, two said lateral protrusion directions were consistent with the protrusion direction of said support.
Existing mirror post has just played light importing effect, and the artificial cornea patient after the installation does not have diopter, for the dioptric effect that obtains, also wants postoperative preparation glasses to reach gauged requirement.The patient of postoperative will wear the correction glasses throughout the year, and this makes troubles for patient's daily life.And, can form the effect of convex lens through the mirror post all is designed to the part of sphere perpendicular to two sides of its axis, and amplify object and also enlarge angular field of view, can also play the effect of correct vision.
During practical implementation,
To the said side of protruding away from the direction of said mirror post, its spherical diameter is 7~8mm;
And/or
To recessed said side, the inside of said mirror post, its spherical diameter is 9.5~21.5mm.
In each embodiment of the present invention, as preferred version, said main body is provided with a plurality of through holes in the periphery of said centre bore.
Can make like this outside the wire netting that embeds body interior is exposed to, when human eye is organized in growth, the tissue growth that the tissue that is positioned at wire netting one side can see through wire netting and opposite side together, thereby support is fixed more firm, prevent that further it from moving.
In addition, through the weight that through hole can also alleviate support is set, the sense of discomfort of people ocular tissue is alleviated.
In each embodiment of the present invention, as preferred version,
The material of said main body is medical polymethyl methacrylate;
And/or
The material of said wire netting is a titanium alloy.
Medical polymethyl methacrylate and titanium alloy all are and agreeing with property of human body material relatively preferably; Tissue is less relatively to the rejection of these two kinds of materials; Therefore use medical polymethyl methacrylate to serve as the material of main body; And the material that uses titanium alloy to serve as wire netting all can reduce the zest of artificial cornea to people ocular tissue, avoids taking place rejection.
In each embodiment of the present invention, as preferred version, the diameter of said mirror post is 2.2~3.5mm.
Large diameter mirror post can provide more wide visual field scope for the patient, but also has the daily nursing difficulty simultaneously, and problems such as pathological changes take place easily; Though and the nursing of undersized mirror post easily, its field range is narrower, and effect is not very desirable.The diameter of mirror post is set to 2.2~3.5mm, and field range can be not too small in this scope, and daily nursing is also simple relatively.
In each embodiment of the present invention, as preferred version, the diameter projected of said main body on its sagittal plane is 7.1~8.1mm; The diameter projected of said wire netting on its sagittal plane is 7~8mm.
People's eyeball is a very accurate tissue, and the implantable artificial cornea more or less can damage eyeball on eyeball, so choose reasonable artificial cornea's size is very crucial; Through being 7.1~8.1mm with the diameter projected of main body on its sagittal plane, can guarantee that the artificial cornea is more convenient in use, and also lower to the influence of eyeball; And embed the structural strength that large-sized wire netting can improve support to greatest extent through inside in main body as far as possible.
In each embodiment of the present invention, as preferred version,
The thickness of said wire netting is 0.06~0.1mm;
And/or
The thickness of said main body is 0.35~0.45mm.
The thin more infringement to eyeball of support is also just few more, but cost of manufacture and implantation difficulty also can be multiplied; Through test of many times, it is all better to confirm that finally thickness is that the main body of 0.35~0.45mm and wire netting that thickness is 0.06~0.1mm are formed its each side cost performance of support.
Shown in Fig. 1 to 3, the artificial cornea comprises support and mirror post, and to be a sphere blocked the shape of the less part in back by a plane of reference to support, and the center of support is provided with centre bore 1; The inwall of centre bore 1 is provided with female thread; Support comprises main body 2 and the wire netting 3 that embeds main body 2 inside; The bearing of trend of wire netting 3 is consistent with the bearing of trend of main body 2; The outer wall of mirror post is provided with the external screw thread that matches with female thread.
The mirror post is sphere is blocked the less part in back by the plane of reference perpendicular to axis structure perpendicular to two sides 4 of its axis; And one of them is to the direction protrusion away from the mirror post, and another is recessed to the inside of stating the mirror post; When support cooperated with the mirror post, the protrusion direction of two sides 4 was consistent with the protrusion direction of support.
To the side 4 of protruding away from the direction of mirror post, its spherical diameter is 8mm; The side 4 that the inside of Xiang Jingzhu is recessed, its spherical diameter are 21.5mm.Main body 2 is provided with a plurality of through holes 5 in the periphery of centre bore 1.The material of main body 2 is medical polymethyl methacrylate; The material of wire netting 3 is a titanium alloy.The diameter of mirror post is 3.5mm.The diameter projected of main body 2 on its sagittal plane is 8.1mm; The diameter projected of wire netting 3 on its sagittal plane is 8mm.The thickness of wire netting is 0.1mm; The thickness of main body is 0.35mm.
The artificial cornea comprises support and mirror post, and to be a sphere blocked the shape of the less part in back by a plane of reference to support, and the center of support is provided with centre bore 1; The inwall of centre bore 1 is provided with female thread; Support comprises main body 2 and the wire netting 3 that embeds main body 2 inside; The bearing of trend of wire netting 3 is consistent with the bearing of trend of main body 2; The outer wall of mirror post is provided with the external screw thread that matches with female thread.
The mirror post is sphere is blocked the less part in back by the plane of reference perpendicular to axis structure perpendicular to two sides 4 of its axis; And one of them is to the direction protrusion away from the mirror post, and another is recessed to the inside of stating the mirror post; When support cooperated with the mirror post, the protrusion direction of two sides 4 was consistent with the protrusion direction of support.
To the side 4 of protruding away from the direction of mirror post, its spherical diameter is 7mm; The side 4 that the inside of Xiang Jingzhu is recessed, its spherical diameter are 9.5mm.Main body 2 is provided with a plurality of through holes 5 in the periphery of centre bore 1.The material of main body 2 is medical polymethyl methacrylate; The material of wire netting 3 is a titanium alloy.The diameter of mirror post is 2.2mm.The diameter projected of main body 2 on its sagittal plane is 7.1mm; The diameter projected of wire netting 3 on its sagittal plane is 7mm.The thickness of wire netting is 0.06mm; The thickness of main body is 0.35mm.
The various embodiment that the embodiment of the invention provides can make up with any-mode as required each other, the technical scheme that obtains through this combination, also within the scope of the invention.Obviously, under the situation that does not break away from the spirit and scope of the present invention, those skilled in the art can carry out various changes and modification to the present invention.Like this, if these changes of the present invention and modification are belonged within the scope of claim of the present invention and equivalent thereof, then the present invention also will comprise these changes and modification.
Claims (8)
1. the artificial cornea is characterized in that, comprises support and mirror post, and to be a sphere blocked the shape of the less part in back by a plane of reference to said support, and the center of said support is provided with centre bore; The inwall of said centre bore is provided with female thread; Said support comprises medical resin material main body of processing and the wire netting that embeds said body interior; The bearing of trend of said wire netting is consistent with the bearing of trend of said main body; The outer wall of said mirror post is provided with the external screw thread that matches with said female thread.
2. artificial cornea as claimed in claim 1 is characterized in that, said mirror post is a cylindricality; Said mirror post is sphere is blocked the less part in back by the plane of reference perpendicular to said axis structure perpendicular to two sides of its axis; And one of them is to the direction protrusion away from said mirror post, and another inside to said mirror post is recessed;
When said support cooperated with said mirror post, two said lateral protrusion directions were consistent with the protrusion direction of said support.
3. artificial cornea as claimed in claim 2 is characterized in that,
To the said side of protruding away from the direction of said mirror post, its spherical diameter is 7~8mm;
And/or
To recessed said side, the inside of said mirror post, its spherical diameter is 9.5~21.5mm.
4. artificial cornea as claimed in claim 1 is characterized in that said main body is provided with a plurality of through holes in the periphery of said centre bore.
5. artificial cornea as claimed in claim 1 is characterized in that,
The material of said main body is medical polymethyl methacrylate;
And/or
The material of said wire netting is a titanium alloy.
6. artificial cornea as claimed in claim 1 is characterized in that, the diameter of said mirror post is 2.2~3.5mm.
7. artificial cornea as claimed in claim 1 is characterized in that, the diameter projected of said main body on its sagittal plane is 7.1~8.1mm; The diameter projected of said wire netting on its sagittal plane is 7~8mm.
8. artificial cornea as claimed in claim 1 is characterized in that,
The thickness of said wire netting is 0.06~0.1mm;
And/or
The thickness of said main body is 0.35~0.45mm.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2012102570994A CN102727324A (en) | 2012-07-23 | 2012-07-23 | Keratoprosthesis |
CN201210469929.XA CN102920532B (en) | 2012-07-23 | 2012-11-19 | Artificial cornea |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2012102570994A CN102727324A (en) | 2012-07-23 | 2012-07-23 | Keratoprosthesis |
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CN102727324A true CN102727324A (en) | 2012-10-17 |
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CN2012102570994A Pending CN102727324A (en) | 2012-07-23 | 2012-07-23 | Keratoprosthesis |
CN201210469929.XA Active CN102920532B (en) | 2012-07-23 | 2012-11-19 | Artificial cornea |
Family Applications After (1)
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CN201210469929.XA Active CN102920532B (en) | 2012-07-23 | 2012-11-19 | Artificial cornea |
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Cited By (6)
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CN102920532A (en) * | 2012-07-23 | 2013-02-13 | 于好勇 | Artificial cornea |
CN105748172A (en) * | 2016-02-23 | 2016-07-13 | 于好勇 | Artificial keratoscope column optical performance detector |
CN112872714A (en) * | 2020-04-13 | 2021-06-01 | 广东佳悦美视生物科技有限公司 | Preparation method of artificial cornea collar |
WO2023098143A1 (en) * | 2021-12-02 | 2023-06-08 | 北京米赫医疗器械有限责任公司 | Artificial cornea based on umbrella-shaped cylinder, and preparation process therefor |
WO2023098144A1 (en) * | 2021-12-02 | 2023-06-08 | 北京米赫医疗器械有限责任公司 | Multifocal artificial cornea and preparation process therefor |
CN117045391A (en) * | 2023-09-18 | 2023-11-14 | 上海视科新工医疗器械有限公司 | Integrated artificial cornea and preparation method thereof |
Families Citing this family (1)
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FR2665356B1 (en) * | 1990-08-02 | 1992-12-04 | Lacombe Emmanuel | ARTIFICIAL CORNEA. |
JP3439809B2 (en) * | 1993-12-24 | 2003-08-25 | 京セラ株式会社 | Artificial cornea |
EP0891753A4 (en) * | 1996-11-13 | 1999-09-22 | Menicon Co Ltd | Artificial cornea |
GB2403908B (en) * | 2003-07-17 | 2007-03-28 | I O Internat Ltd | Artificial cornea |
US20060173539A1 (en) * | 2005-01-31 | 2006-08-03 | Yichieh Shiuey | Corneal implants and methods and systems for placement |
US20070168025A1 (en) * | 2006-01-13 | 2007-07-19 | Sohrab Darougar | Artificial cornea |
CN201015616Y (en) * | 2006-11-16 | 2008-02-06 | 于好湧 | Artificial cornea device |
US20080255663A1 (en) * | 2007-04-13 | 2008-10-16 | Akpek Esen K | Artificial Cornea and Method of Making Same |
CN201029958Y (en) * | 2007-04-19 | 2008-03-05 | 同济大学 | Non-penetrating integrated artificial cornea |
CN201160919Y (en) * | 2008-03-05 | 2008-12-10 | 黄一飞 | Novel split type artificial cornea |
CN102727324A (en) * | 2012-07-23 | 2012-10-17 | 于好勇 | Keratoprosthesis |
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- 2012-07-23 CN CN2012102570994A patent/CN102727324A/en active Pending
- 2012-11-19 CN CN201210469929.XA patent/CN102920532B/en active Active
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102920532A (en) * | 2012-07-23 | 2013-02-13 | 于好勇 | Artificial cornea |
CN105748172A (en) * | 2016-02-23 | 2016-07-13 | 于好勇 | Artificial keratoscope column optical performance detector |
CN112872714A (en) * | 2020-04-13 | 2021-06-01 | 广东佳悦美视生物科技有限公司 | Preparation method of artificial cornea collar |
CN112872714B (en) * | 2020-04-13 | 2022-08-12 | 广东佳悦美视生物科技有限公司 | Preparation method of artificial cornea collar |
WO2023098143A1 (en) * | 2021-12-02 | 2023-06-08 | 北京米赫医疗器械有限责任公司 | Artificial cornea based on umbrella-shaped cylinder, and preparation process therefor |
WO2023098144A1 (en) * | 2021-12-02 | 2023-06-08 | 北京米赫医疗器械有限责任公司 | Multifocal artificial cornea and preparation process therefor |
CN117045391A (en) * | 2023-09-18 | 2023-11-14 | 上海视科新工医疗器械有限公司 | Integrated artificial cornea and preparation method thereof |
Also Published As
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CN102920532B (en) | 2014-11-26 |
CN102920532A (en) | 2013-02-13 |
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Application publication date: 20121017 |