CN102726573A - Health tea granule for preventing dyslipidemia - Google Patents

Abstract

Provided is a health tea granule for preventing dyslipidemia with good and fast effects, pertaining to a field of nutrition food. Grape, soja, helianthus tuberosus and the like are used as raw materials of the invention. The health tea granule of the invention lowers lipid, relieves arteriosclerosis and protects heart. The health tea granule highlights points, takes into account both superficial and radical aspects, and is surely a lipid-lowering prescription with good and fast effects.

Description

A kind of health tea electuary that prevents dyslipidemia

Technical field

The invention belongs to the nutraceutical field.

Background technology

Along with people's degree that is well off is increasingly high, high fat diet is commonplace.The dyslipidemia person is more and more---and cholesterol, triglycerides, low-density lipoprotein increase unusually in the blood plasma.These unusual lipidosis that raise form AP on vascular wall, cause vascular wall narrow even inaccessible, cause angina pectoris, myocardial infarction, the cerebral infarction serious consequence of waiting indefinitely, life threatening.People have had hyperlipidemia, should go to hospital to see the doctor, the medication treatment of following the doctor's advice, and this is absolutely necessary.Broad masses of the people also hope the way prophylaxis of hyperlipidemia through dietotherapy.But the food of lipopenicillinase in the market is not too many, and it is obvious inadequately to exist effect, the slower problem that takes effect, and the masses are dissatisfied to this.

To problem set forth above, the present invention provides a kind of health tea electuary that prevents dyslipidemia, and it is obvious inadequately that it can solve in the past in this type of antihyperlipidemic product effect, and the slower problem that takes effect has advantage effective, instant effect.

Summary of the invention

The present invention realizes through following technical scheme:

1, a kind of health tea electuary that prevents dyslipidemia adopts Chinese medicine material and food preparation, and prescription is by weight being:

Grape 6---10 parts of 10 portions of soybean 7---12 portions of jerusalem artichokes 6---

The health tea electuary of this prevention dyslipidemia is processed by following method:

(1) by above-mentioned weight ratio, grape is extracted vine polyphenol, process is: grape is cleaned smashed to pieces, separate grape pip with grape skin and flesh; With Microwave Extraction Grape Skin polyphenol, process conditions are earlier: add 50% ethanol by 1: 25 solid-liquid ratio, microwave power 180W handled 35 seconds, in 70 ℃ of water-bath lixiviate 25min; Ethanol is reclaimed in the back, concentrate, dry, pulverize, the extract fine powder; Use microwave lixiviate grape pip anthocyanagen then, process conditions are: 70 ℃ of ethanolic solutions, by 1: 9 solid-liquid ratio; Microwave treatment 10 seconds is in 50 ℃ of water-bath lixiviate 30 min, thereafter; Refining with macroporous absorbent resin; The grape pip anthocyanagen is adsorbed on the resin, adsorbs-desorb with other material and separate, reach the purpose of purifying; Above-mentioned two kinds of extracts are mixed, stir, get vine polyphenol extract fine powder;

(2) by above-mentioned weight ratio, soybean is extracted isoflavones, process is: with the soybean sheet after water, pure equal solvent leach; Heating separates dissolution fluid, uses resin adsorption; Wash resin again; Through water, the certain density isoflavones liquid of alcoholic solvent stripping, vacuum drying gets the soybean isoflavone extract fine powder;

(3) by above-mentioned weight ratio, jerusalem artichoke is extracted FOS, process is: with bright jerusalem artichoke clean, chopping, add 3 times of water by volume, 90 ~ 95 ℃ of lixiviates 2 times, each 30min filters merging filtrate; To filtrate and handle through calcium hydroxide, neutralization makes solution PH=8 ~ 10, produces cotton-shaped calcium carbonate; Deposition centrifugal filtration, the jerusalem artichoke liquid that obtains clarifying, spent ion exchange resin is handled jerusalem artichoke liquid; Flow out liquid and be placed under the room temperature PH=1.5 ~ 2.0, acidolysis 6 hours; Cross strong anionic resin, juice concentrates, spray-drying, gets jerusalem artichoke extract FOS fine powder;

(4) above-mentioned (1), (2), (3) extract fine powder are mixed, stir, process fine particle, the pouch of packing into, every pouch include extract 1.2 grams, process the health tea electuary of prevention dyslipidemia.

Raw material in this prescription is that medicine-food two-purpose kind and the food that the Ministry of Public Health announces can be used kind.

The present invention develops according to the folk tradition prescription meticulously.We reuse the vine polyphenol of grape extraction; From grape fruit pulp and seed, extract; What wherein content was maximum is exactly anthocyanagen; Anthocyanagen can effectively reduce cholesterol and low-density lipoprotein, and the prevention thrombosis helps avoid the hardening of arterial elasticity fiber and causes the generation of artery sclerosis and cardiovascular and cerebrovascular disease ^1.Minister is with the FOS of jerusalem artichoke extraction, and jerusalem artichoke is exactly a Jerusalem artichoke, also claims Jerusalem artichoke, is the edible a kind of vegetables for many years of common people's salted white, and FOS belongs to indigestion sugar, can not increase blood sugar and insulin after the food.FOS has the function of enhance immunity power; Can increase the antibody forming cell's number about 50% in the body; It is about 50% to improve the NK cytoactive, and FOS has the effect of tangible adjusting blood fat, and (rat is raised the body weight with 0.5g/ ㎏ to reduce the contents level of cholesterol in serum and triglycerides; Cholesterol descends 30.5%, and triglycerides descends 40%) ^2.The isoflavones that is aided with the soybean extraction, it has reducing blood lipid, suppresses the artery sclerosis effect.In October, 1999, the soybean protein that FDA Food and Drug Administration (FDA) formally will contain isoflavones is recommended as reduction blood cholesterol concentration, reduces and suffers from the dangerous healthy food of coronary heart disease.25g soybean protein (containing 0.2% isoflavones approximately) is taken in the U.S. FDA suggestion every day, then can make low-density lipoprotein cholesterol level reduction about 10% in the blood.Adopt isoflavones (dosage is 56mg and 90mg) that postmenopausal women's hypercholesterolemia is treated, find that isoflavones can improve the level of HDL-C ^3.Make a general survey of full side, all flavor compatibilities complement each other, and have both reduced blood fat, alleviate artery sclerosis again, and the protection heart is given prominence to the key points, giving consideration to both the incidental and fundamental, and lipopenicillinase good recipe really, it has effective, the advantage of instant effect.

The specific embodiment

Through following embodiment the present invention is done and to specify:

1, get following prescription (weight is unit by gram):

Grape 6000 gram soybean 7000 gram jerusalem artichokes 6000 grams

Press predetermined weight, respectively grape, soybean, jerusalem artichoke are extracted, get extract fine powder 950 grams with the method for content of the present invention (1), (2), (3); The said extracted thing is mixed; Stir, process fine particle, the pouch of packing into; Every pouch includes extract 1.2 grams, processes health tea electuary 791 pouches of prevention dyslipidemia.

2, get following prescription (weight is unit by gram):

Grape 10000 gram soybean 12000 gram jerusalem artichokes 10000 grams

By above-mentioned same method, process health tea electuary 1333 pouches of prevention dyslipidemia, every pouch includes extract 1.2 grams.

3, get following prescription (by weight):

7 parts of 9 portions of jerusalem artichokes of 7 portions of soybean of grape

By above-mentioned same method, process the health tea electuary of prevention dyslipidemia, every pouch includes extract 1.2 grams.

4, get following prescription (by weight):

9 parts of 11 portions of jerusalem artichokes of 9 portions of soybean of grape

By above-mentioned same method, process the health tea electuary of prevention dyslipidemia, every pouch includes extract 1.2 grams.

Clinical data:

The present invention is an example with traditional Chinese medical science dyslipidemia, through 17 routine clinical observations.Select the tcm diagnosis dyslipidemia to increase and be standard: the serum inspection has hyperlipidemia on an empty stomach---total triglycerides>and 150mg/dl (normal value 70---150), T-CHOL>200 mg/dl (normal value 129---179), LDL-C >=160 mg/dl (normal value 65 ~ 175); As above index can be made a definite diagnosis.In making a definite diagnosis the object of observation, the male sex's 2 examples, women's 15 examples do not have other serious disease, and the age is 42 years old-75 years old, 61.7 years old mean age.

Efficacy determination:

1, produce effects: serum inspection T-CHOL, triglycerides, LDL-C all meet normal value on an empty stomach.

2, effective: as to have more than one in above-mentioned three indexs to meet normal value.

3, invalid: numerical value does not have significant change in above-mentioned three indexs.

During clinical trial, withdraw other medicines and health nutrient.Take the health tea electuary of the prevention dyslipidemia of the specific embodiment of the invention 1 making, observed 4 months, be one-period.Instructions of taking: every day 1 time, each 1 pouch, every pouch include extract 1.2 gram, warm water delivery service after meal, index promptly has alleviation after 1 month, take 4 months after, index is obviously improved.17 philtrums of clinical trial, produce effects 7 people, effective 8 people, invalid 2 people, total effective rate 88.2%.

Claims (1)

1. health tea electuary that prevents dyslipidemia is characterized in that: said health tea is to adopt the raw-food material preparation, and the weight proportion of raw-food material is:

Grape 6---10 parts of 10 portions of soybean 7---12 portions of jerusalem artichokes 6---

The health tea electuary of this prevention dyslipidemia is processed by following method:

(1) by above-mentioned weight ratio, grape is extracted vine polyphenol, process is: grape is cleaned smashed to pieces, separate grape pip with grape skin and flesh; With Microwave Extraction Grape Skin polyphenol, process conditions are earlier: add 50% ethanol by 1: 25 solid-liquid ratio, microwave power 180W handled 35 seconds, in 70 ℃ of water-bath lixiviate 25min; Ethanol is reclaimed in the back, concentrate, dry, pulverize, the extract fine powder; Use microwave lixiviate grape pip anthocyanagen then, process conditions are: 70 ℃ of ethanolic solutions, by 1: 9 solid-liquid ratio; Microwave treatment 10 seconds is in 50 ℃ of water-bath lixiviate 30 min, thereafter; Refining with macroporous absorbent resin; The grape pip anthocyanagen is adsorbed on the resin, adsorbs-desorb with other material and separate, reach the purpose of purifying; Above-mentioned two kinds of extracts are mixed, stir, get vine polyphenol extract fine powder;

(2) by above-mentioned weight ratio, soybean is extracted isoflavones, process is: with the soybean sheet after water, pure equal solvent leach; Heating separates dissolution fluid, uses resin adsorption; Wash resin again; Through water, the certain density isoflavones liquid of alcoholic solvent stripping, vacuum drying gets the soybean isoflavone extract fine powder;

(3) by above-mentioned weight ratio, jerusalem artichoke is extracted FOS, process is: with bright jerusalem artichoke clean, chopping, add 3 times of water by volume, 90 ~ 95 ℃ of lixiviates 2 times, each 30min filters merging filtrate; To filtrate and handle through calcium hydroxide, neutralization makes solution PH=8 ~ 10, produces cotton-shaped calcium carbonate; Deposition centrifugal filtration, the jerusalem artichoke liquid that obtains clarifying, spent ion exchange resin is handled jerusalem artichoke liquid; Flow out liquid and be placed under the room temperature PH=1.5 ~ 2.0, acidolysis 6 hours; Cross strong anionic resin, juice concentrates, spray-drying, gets jerusalem artichoke extract FOS fine powder;

(4) above-mentioned (1), (2), (3) extract fine powder are mixed, stir, process fine particle, the pouch of packing into, every pouch include extract 1.2 grams, process the health tea electuary of prevention dyslipidemia.