CN102724984A - 肠球菌细胞壁组分及其抗菌用途 - Google Patents

肠球菌细胞壁组分及其抗菌用途 Download PDF

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Publication number
CN102724984A
CN102724984A CN2010800617016A CN201080061701A CN102724984A CN 102724984 A CN102724984 A CN 102724984A CN 2010800617016 A CN2010800617016 A CN 2010800617016A CN 201080061701 A CN201080061701 A CN 201080061701A CN 102724984 A CN102724984 A CN 102724984A
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CN
China
Prior art keywords
enterococcus
cell
antibody
wall component
infection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2010800617016A
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English (en)
Chinese (zh)
Inventor
约翰尼斯·修伯纳
克里斯蒂安·塞拉克尔
奥托·赫斯特
兹比格涅夫·卡钦斯基
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitaetsklinikum Freiburg
Original Assignee
Universitaetsklinikum Freiburg
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Filing date
Publication date
Application filed by Universitaetsklinikum Freiburg filed Critical Universitaetsklinikum Freiburg
Publication of CN102724984A publication Critical patent/CN102724984A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN2010800617016A 2010-01-19 2010-01-19 肠球菌细胞壁组分及其抗菌用途 Pending CN102724984A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2010/000285 WO2011088843A1 (en) 2010-01-19 2010-01-19 Enterococcal cell wall components and antibacterial use thereof

Publications (1)

Publication Number Publication Date
CN102724984A true CN102724984A (zh) 2012-10-10

Family

ID=41820228

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010800617016A Pending CN102724984A (zh) 2010-01-19 2010-01-19 肠球菌细胞壁组分及其抗菌用途

Country Status (12)

Country Link
US (1) US9005622B2 (de)
EP (1) EP2525800B1 (de)
JP (1) JP5746217B2 (de)
KR (1) KR20120132482A (de)
CN (1) CN102724984A (de)
AU (1) AU2010342872B2 (de)
BR (1) BR112012017870A2 (de)
CA (1) CA2787184C (de)
IL (1) IL220681A0 (de)
MX (1) MX2012008426A (de)
RU (1) RU2559543C2 (de)
WO (1) WO2011088843A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106413737A (zh) * 2014-05-29 2017-02-15 株式会社绿十字 用于预防或治疗金黄色葡萄球菌感染的组合物

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2644613T3 (en) 2012-03-30 2015-01-26 Universitätsklinikum Freiburg Cell wall polymers from Enterococcus faecalis and applications thereof
US9777076B2 (en) 2012-07-16 2017-10-03 Pfizer Inc. Saccharides and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999008705A1 (en) * 1997-08-20 1999-02-25 Brigham And Women's Hospital Capsular polysaccharides from enterococci
US6756361B1 (en) * 1997-10-14 2004-06-29 Nabi Enterococcus antigens and vaccines
AUPQ137699A0 (en) 1999-07-02 1999-07-22 University Of New England, The Control of acidosis
US20030113350A1 (en) * 2001-09-19 2003-06-19 Fattom Ali I. Glycoconjugate vaccines for use in immune-compromised populations
US20060121058A1 (en) 2002-08-08 2006-06-08 Children's Medical Center Corporation Anti-pneumococcal preparations
US7320874B2 (en) 2003-07-08 2008-01-22 Aventis Pasteur Sa Assaying the teichoic acids of gram+ bacteria
RU2296583C1 (ru) * 2005-08-02 2007-04-10 Федеральное государственное образовательное учреждение высшего профессионального образования Кубанский государственный аграрный университет Вакцина, ассоциированная против сальмонеллеза и энтерококковой инфекции нутрий

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106413737A (zh) * 2014-05-29 2017-02-15 株式会社绿十字 用于预防或治疗金黄色葡萄球菌感染的组合物

Also Published As

Publication number Publication date
AU2010342872A1 (en) 2012-07-26
EP2525800A1 (de) 2012-11-28
KR20120132482A (ko) 2012-12-05
AU2010342872B2 (en) 2014-09-25
MX2012008426A (es) 2012-11-23
US9005622B2 (en) 2015-04-14
BR112012017870A2 (pt) 2017-09-19
WO2011088843A1 (en) 2011-07-28
RU2559543C2 (ru) 2015-08-10
EP2525800B1 (de) 2018-07-04
US20120282268A1 (en) 2012-11-08
CA2787184C (en) 2016-03-22
JP2013517308A (ja) 2013-05-16
IL220681A0 (en) 2012-08-30
JP5746217B2 (ja) 2015-07-08
RU2012135466A (ru) 2014-02-27
CA2787184A1 (en) 2011-07-28

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Application publication date: 20121010