CN102697892B - Medicine for treating rheumatoid arthritis - Google Patents
Medicine for treating rheumatoid arthritis Download PDFInfo
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- CN102697892B CN102697892B CN201210131787.6A CN201210131787A CN102697892B CN 102697892 B CN102697892 B CN 102697892B CN 201210131787 A CN201210131787 A CN 201210131787A CN 102697892 B CN102697892 B CN 102697892B
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Abstract
The invention provides a medicine for treating rheumatoid arthritis. The medicine is prepared from the raw materials of traditional Chinese medicine in proportion by weight as follows: 12 to 15 parts of radix stephaniae tetrandrae, 12 to 15 parts of gentiana macrophylla, 6 to 8 parts of ramulus mori, 6 to 8 parts of radix clematidis, 9 to 12 parts of lignum sappan, 9 to 12 parts of himalayan teasel root, 8 to 10 parts of potentilla discolor bge, 9 to 12 parts of Chinese angelica, 9 to 12 parts of astragalus, 6 to 8 parts of carthamus tinctorius, 9 to 12 parts of thinleaf milkwort root-bark, and 6 to 8 parts of liquorice. The medicine is prepared by the steps of: placing the raw materials of traditional Chinese medicine into a container; adding water the weight of which is 4 to 6 times the total weight of the raw materials and soaking for 30 to 50 minutes; boiling the water through a strong fire; and then decocting for 40 to 60 minutes with a soft fire; taking out the filtrate; adding water the weight of which 60% of the original weight of the water added at the first time to the residue; decocting for 50 minutes with the soft fire; taking out the filtrate; combining the two filtrates; powdering 1 to 2 parts of cordyceps sinensis based on the weight ratio; and uniformly mixing with the mixed filtrate so as to obtain the medicine for treating rheumatoid arthritis. According to the invention, the raw materials of traditional Chinese medicine are prepared into medicine for taking orally, thus relieving the symptoms.
Description
Technical field
The present invention relates to medicine, is a kind of medicine for the treatment of rheumatoid arthritis.
Background technology
Rheumatoid arthritis is a kind of commonly encountered diseases, and in certain areas, sickness rate is high.This disease is with joint and surrounding tissue inflammation, atrophy and causes joint deformity and the stiff disease that is fixed as feature, belongs to autoimmune disease.The cause of disease of this chronic disease is not bright so far.Its classical symptom is arthralgia, and secondly common finger, wrist and the gonalgia are elbow, ankle, shoulder, the hip arthralgia etc., and joint motions are limited, and ankylosis symptom appears in the morbidity later stage, and small number of patients is with lymphadenectasis, pericarditis, pleuritis etc.This sick medicine for the treatment of is divided into doctor trained in Western medicine and the large class of the traditional Chinese medical science two at present.Because this disease is chronic disease, need long-term prescription, and the secondary use of the poison of Western medicine is larger, therefore, many patients select treatment by Chinese herbs.
Summary of the invention
The object of this invention is to provide a kind of medicine for the treatment of rheumatoid arthritis, it is for oral administration that it adopts raw material of Chinese medicine to make medicament, thus mitigation symptoms.
The present invention for achieving the above object, be achieved through the following technical solutions: a kind of medicine for the treatment of rheumatoid arthritis, by the raw material of Chinese medicine of following weight ratio, made: Radix Stephaniae Tetrandrae 12-15, Radix Gentianae Macrophyllae 12-15, Ramulus Mori 6-8, Radix Clematidis 6-8, Lignum Sappan 9-12, Radix Dipsaci 9-12, Herba Potentillae Discoloris 8-10, Cordyceps 1-2, Radix Angelicae Sinensis 9-12, Radix Astragali 9-12, Flos Carthami 6-8, Radix Polygalae 9-12, Radix Glycyrrhizae 6-8.
Described a kind of medicine for the treatment of rheumatoid arthritis, is made by the raw material of Chinese medicine of following weight ratio: Radix Stephaniae Tetrandrae 13, Radix Gentianae Macrophyllae 13, Ramulus Mori 7, Radix Clematidis 7, Lignum Sappan 11, Radix Dipsaci 11, Herba Potentillae Discoloris 9, Cordyceps 1.5, Radix Angelicae Sinensis 11, the Radix Astragali 11, Flos Carthami 7, Radix Polygalae 11, Radix Glycyrrhizae 7.
Described a kind of medicine for the treatment of rheumatoid arthritis, is made by the raw material of Chinese medicine of following weight ratio: Radix Stephaniae Tetrandrae 15, Radix Gentianae Macrophyllae 15, Ramulus Mori 8, Radix Clematidis 8, Lignum Sappan 12, Radix Dipsaci 12, Herba Potentillae Discoloris 10, Cordyceps 2, Radix Angelicae Sinensis 12, the Radix Astragali 12, Flos Carthami 8, Radix Polygalae 12, Radix Glycyrrhizae 8.
Described a kind of medicine for the treatment of rheumatoid arthritis, is made by the raw material of Chinese medicine of following weight ratio: Radix Stephaniae Tetrandrae 12, Radix Gentianae Macrophyllae 12, Ramulus Mori 6, Radix Clematidis 6, Lignum Sappan 9, Radix Dipsaci 9, Herba Potentillae Discoloris 8, Cordyceps 1, Radix Angelicae Sinensis 9, the Radix Astragali 9, Flos Carthami 6, Radix Polygalae 9, Radix Glycyrrhizae 6.
Described a kind of manufacture method for the treatment of the medicine of rheumatoid arthritis, get by weight Radix Stephaniae Tetrandrae 12-15, Radix Gentianae Macrophyllae 12-15, Ramulus Mori 6-8, Radix Clematidis 6-8, Lignum Sappan 9-12, Radix Dipsaci 9-12, Herba Potentillae Discoloris 8-10, Radix Angelicae Sinensis 9-12, Radix Astragali 9-12, Flos Carthami 6-8, Radix Polygalae 9-12, Radix Glycyrrhizae 6-8 raw material of Chinese medicine is inserted in container, add crude drug gross weight 4-6 water soaking 30-50 minute doubly, intense fire makes after water boiling, after changing 40-60 at a simmer minute into, filtrate is poured out, in medicinal residues, add again the water yield 60% for the first time, 50 minutes at a simmer, filtrate is poured out, twice filtrate is merged, by weight Cordyceps 1-2 is made to powder, mix homogeneously with filtrate, be the medicine for the treatment of rheumatoid arthritis.
The Main Function of raw material of Chinese medicine of the present invention: Radix Stephaniae Tetrandrae is used for dispelling rheumatism, inducing diuresis to remove edema; Radix Gentianae Macrophyllae is for wind-damp dispelling, relaxing muscles and tendons network, clearind deficient heat, clearing away damp-heat; Ramulus Mori is for wind-damp dispelling, the meridian dredging, row aqueous vapor; Wheeling is stretched for wind-damp dispelling, the meridian dredging, the bone that disappears and is choked; Lignum Sappan is for blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain; Radix Dipsaci is for invigorating the liver and kidney, reuniting the fractured tendons and bones, promoting the circulation of blood arteries and veins; Herba Potentillae Discoloris is for heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery; Cordyceps is for kidney invigorating and YANG supporting, adjusting immune system; Radix Angelicae Sinensis is used for enriching blood and invigorates blood circulation; The Radix Astragali is admittedly de-for benefiting QI for strengthening the superficies, arresting sweating, inducing diuresis to remove edema; Flos Carthami is for promoting blood circulation to restore menstrual flow and eliminating stasis to stop pain; Radix Polygalae be used for calming the nerves Fructus Alpiniae Oxyphyllae, eliminating phlegm for diminishing swelling; Radix Glycyrrhizae is for coordinating the actions of various ingredients in a prescription.Above-mentioned all medicine combinations, have the effects such as wind-damp dispelling, inducing diuresis to remove edema, channels sootheing and network vessel quickening, removing blood stasis to reduce swelling, heat-clearing and toxic substances removing, invigorating the liver and kidney, blood circulation promoting and blood stasis dispelling, and primary treatment rheumatoid is effective fast.
Medicine of the present invention is secret prescription handed down in the family from generation to generation, has used several generations, and effect is remarkable.Medicament of the present invention is decoction, and every day, potion, serviced once sooner or later, within 15 days, was a course for the treatment of.
Clinical statistics data in recent years: 120 routine patients, the age, wherein 42 years old above patient was 83 examples, male 7 examples, female's 49 examples, the course of disease 2 to 9 years in 21-69 year.Patient is all rheumatoid arthritis by hospital diagnosis.94 patient's symptoms are joints of hand and wrist, knee joint, joints of foot pain, ankylosis when rise morning, and 18 routine patient's symptoms are shoulder, elbow, the hip arthralgia, ankylosis when rise morning, 8 routine patient's handss, knee joint, hip joint limitation of activity are curved.
Treatment criterion: effective: pain relief.Cure: clinical symptom disappearance.Take a turn for the better: clinical symptoms obviously alleviates.Invalid: the symptom after treatment is front without significant change with treatment.
Above-mentioned patient take medicine of the present invention after 1 course for the treatment of obvious effective rate be 100%, after 4-8 the course for the treatment of of taking medicine, cure 92 examples, 22 examples that take a turn for the better, invalid 6 examples, cure rate is 76.7%, improvement rate is 18.3%, inefficiency is 5%.
Model case:
1, Jiang court, female, 61 years old, Xuecheng District, Zaozhuang City, Shandong Province, patient's readme: ill 7 years, the gonalgia removes hospital diagnosis after 3 years be rheumatoid arthritis, took the multiple antibiotic medicine of vitamin, amcinonide, and symptom is not clearly better, after develop into knee joint and can not stretch, difficulty in walking, hospital diagnoses again, need to change bone-specific drug.Clothes have medicament of the present invention after the course for the treatment of, and pain obviously alleviates, and takes after 4 courses for the treatment of, and lower limb can stretch walking, continue to take to 8 courses for the treatment of, and the gonalgia disappears, and walking freely.Examination in hospital serum rheumatoid factor (SRF) is negative, serum negative antinuclear antibodies.Tracing observation not recurrence in 1 year.
2, Li Zhonghong, female, 69 years old, Gao Yan village, Shi Jing town, Fei County, Shandong Province, patient's readme, ill 10 years, during morbidity Anqi, hands, foot, the gonalgia had, and play joint stiffness sense morning obvious, joints of hand distortion afterwards, limitation of activity, hospital diagnosis is rheumatoid arthritis.Intermittently ate the medicines such as aspirin, antibiotic medicine, prednisone, cyclophosphamide, the initial stage symptom of taking medicine can be alleviated sometimes, long-term taking DeGrain.Take one of the medicament of the present invention posterior joint pain relief course for the treatment of, continue to take to 8 courses for the treatment of, pain symptom disappears, and foot joint, knee joint activity freely, play stiff transference cure morning, and joints of hand limitation of activity symptom is improved.Tracing observation not recurrence in 2 years.
The specific embodiment
A kind of medicine for the treatment of rheumatoid arthritis of the present invention, is made by the raw material of Chinese medicine of following weight ratio: Radix Stephaniae Tetrandrae 12-15, Radix Gentianae Macrophyllae 12-15, Ramulus Mori 6-8, Radix Clematidis 6-8, Lignum Sappan 9-12, Radix Dipsaci 9-12, Herba Potentillae Discoloris 8-10, Cordyceps 1-2, Radix Angelicae Sinensis 9-12, Radix Astragali 9-12, Flos Carthami 6-8, Radix Polygalae 9-12, Radix Glycyrrhizae 6-8.
Said medicine is by weight there being following multiple combination:
1, Radix Stephaniae Tetrandrae 13, Radix Gentianae Macrophyllae 13, Ramulus Mori 7, Radix Clematidis 7, Lignum Sappan 11, Radix Dipsaci 11, Herba Potentillae Discoloris 9, Cordyceps 1.5, Radix Angelicae Sinensis 11, the Radix Astragali 11, Flos Carthami 7, Radix Polygalae 11, Radix Glycyrrhizae 7.
2, Radix Stephaniae Tetrandrae 15, Radix Gentianae Macrophyllae 15, Ramulus Mori 8, Radix Clematidis 8, Lignum Sappan 12, Radix Dipsaci 12, Herba Potentillae Discoloris 10, Cordyceps 2, Radix Angelicae Sinensis 12, the Radix Astragali 12, Flos Carthami 8, Radix Polygalae 12, Radix Glycyrrhizae 8.
3, Radix Stephaniae Tetrandrae 12, Radix Gentianae Macrophyllae 12, Ramulus Mori 6, Radix Clematidis 6, Lignum Sappan 9, Radix Dipsaci 9, Herba Potentillae Discoloris 8, Cordyceps 1, Radix Angelicae Sinensis 9, the Radix Astragali 9, Flos Carthami 6, Radix Polygalae 9, Radix Glycyrrhizae 6.
4, Radix Stephaniae Tetrandrae 14, Radix Gentianae Macrophyllae 14, Ramulus Mori 8, Radix Clematidis 8, Lignum Sappan 10, Radix Dipsaci 10, Herba Potentillae Discoloris 9, Cordyceps 2, Radix Angelicae Sinensis 10, the Radix Astragali 10, Flos Carthami 8, Radix Polygalae 10, Radix Glycyrrhizae 7.
Each embodiment of the present invention all makes as follows: get by weight Radix Stephaniae Tetrandrae 12-15, Radix Gentianae Macrophyllae 12-15, Ramulus Mori 6-8, Radix Clematidis 6-8, Lignum Sappan 9-12, Radix Dipsaci 9-12, Herba Potentillae Discoloris 8-10, Radix Angelicae Sinensis 9-12, Radix Astragali 9-12, Flos Carthami 6-8, Radix Polygalae 9-12, Radix Glycyrrhizae 6-8 raw material of Chinese medicine is inserted in container, add crude drug gross weight 4-6 water soaking 30-50 minute doubly, intense fire makes after water boiling, after changing 40-60 at a simmer minute into, filtrate is poured out, in medicinal residues, add again the water yield 60% for the first time, 50 minutes at a simmer, filtrate is poured out, twice filtrate is merged, by weight Cordyceps 1-2 is made to powder, mix homogeneously with filtrate, be the medicine for the treatment of rheumatoid arthritis.
Medicine of the present invention is decoction, but makes tablet, capsule or powder after also can adding as required medical auxiliary materials.
Claims (1)
1. a medicine for the treatment of rheumatoid arthritis, is characterized in that: the raw material of Chinese medicine by following weight ratio is made: Radix Stephaniae Tetrandrae 15, Radix Gentianae Macrophyllae 15, Ramulus Mori 8, Radix Clematidis 8, Lignum Sappan 12, Radix Dipsaci 12, Herba Potentillae Discoloris 10, Cordyceps 2, Radix Angelicae Sinensis 12, the Radix Astragali 12, Flos Carthami 8, Radix Polygalae 12, Radix Glycyrrhizae 8.
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KR19990083970A (en) * | 1999-09-03 | 1999-12-06 | 정진호 | Phamaceutical compositions for treating rheumatism and method for production thereof |
KR20100042337A (en) * | 2008-10-16 | 2010-04-26 | 변정윤 | The composition of traditional oriental medicines for reheumatoid arthritis and the method of preparing medicine for it |
KR20110009379A (en) * | 2009-07-22 | 2011-01-28 | 한국맥널티 주식회사 | Galenical extract-containing tablet having shortened disintergration time |
DE102009050407A1 (en) * | 2009-10-22 | 2011-06-22 | Bionorica SE, 92318 | Anti-inflammatory agent containing hydrolysates from plant extracts |
KR20110137047A (en) * | 2010-06-16 | 2011-12-22 | 재단법인 제주테크노파크 | Anti-inflammation composition using an extract of hypochoeris radicata |
CN102225102B (en) * | 2011-06-14 | 2012-10-10 | 南京正宽医药科技有限公司 | Medicinal liquor for treating rheumatoid arthritis |
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Address after: 277011, No. 338, reed bridge village, Tao Zhuang Town, Xuecheng District, Shandong, Zaozhuang Applicant after: Jiang Zhengxia Address before: Central Yuhan road Ji'nan City, Shandong province 250002 City No. 39 North Building 5, Room 301 Applicant before: Jiang Zhengxia |
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