CN102697460A - Doppler laser optical coherence tomography (OCT) hard colposcope system - Google Patents
Doppler laser optical coherence tomography (OCT) hard colposcope system Download PDFInfo
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- CN102697460A CN102697460A CN2012100180594A CN201210018059A CN102697460A CN 102697460 A CN102697460 A CN 102697460A CN 2012100180594 A CN2012100180594 A CN 2012100180594A CN 201210018059 A CN201210018059 A CN 201210018059A CN 102697460 A CN102697460 A CN 102697460A
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Abstract
The invention belongs to the field of medical instruments, and specifically discloses a Doppler laser optical coherence tomography (OCT) hard colposcope system. The Doppler laser OCT hard colposcope system comprises a hard colposcope, and a cold light source host and a photographic host which are connected with the hard colposcope, wherein a Doppler laser data acquisition module and an OCT data acquisition module are arranged on the hard colposcope, and the hard colposcope is also connected with a Doppler processing host which analyzes and processes the data which is acquired by the Doppler laser data acquisition module, and is further connected with an OCT processing host which analyzes and processes the data which is acquired by the OCT data acquisition module. The Doppler laser data acquisition module and the OCT data acquisition module are integrated on a mixed module, namely a flexible head, through coordinating with a Doppler host and an OCT host to process, the more accurate dynamic images and more exquisite tomographic lesion images of surface vessels between vaginal walls are obtained, so precise and exact data support is provided for the diagnosis and treatment of doctors..
Description
Technical field
The invention belongs to field of medical appliances, be specifically related to a kind of laser doppler OCT vaginoscope system.
Background technology
Colposcope; It is the important medical apparatus and instruments of current diagnosis vagina pathological changes; It is that electro-photographic probe through being installed on the colposcope front end is transmitted in the electronic computer processing center with the image of vaginal wall, after be shown on the monitor screen, can be observed the minor variations between vaginal wall.
Doppler principle all is used widely in every field, utilizes the Doppler effect of laser beam in the industry, is used for the speed of Measuring Object, and its degree of accuracy is high; Medically utilize hyperacoustic Doppler effect, observation patient body situation.The laser doppler technology slowly also gets into medical domain at present; Utilize the Doppler effect of laser to measure the microcirculation blood flow of various tissues and organ with the mode of noinvasive or Wicresoft; In addition can also do series of analysis calculates; Comprise microcirculatory hemodynamics variation, and heart is beated synchronously even double pulse etc., accomplish the purpose of accurate monitoring.
Equally; OCT (Optical Coherence Tomography; Optical Coherence Tomography Imaging Technology) utilizes the weak coherent light principle of interference; Detect the backscatter signals of tested tissue different depth, and obtain organizing two dimension or three dimensional depth structural images, have characteristics such as radiationless, non-intruding, high-resolution and high detection sensitivity through scanning.
The OCT technology has obtained effective application in ophthalmologic examination, and gets involved in the human organ, the microminiaturization of OCT technology is applied to intraorganic disease detect, and is not still effectively carried out at present.
But at present, in colposcope, still there are not fine application laser doppler technology and OCT technology.If colposcope can be gathered the advantage of laser doppler technology and OCT technology, accurate more dynamic image of top layer blood vessel and meticulousr tomography pathological changes image with obtaining between vaginal wall further improve the accuracy of diagnosis and the success rate of treatment.
Therefore, design is a kind of extremely urgent with the vaginoscope system that laser doppler is technological, OCT is technological to be used in combination with colposcope.
Summary of the invention
The object of the present invention is to provide a kind of laser doppler OCT vaginoscope system; The advantage of set laser doppler technology and OCT technology; Accurate more dynamic image of top layer blood vessel and meticulousr tomography pathological changes image with obtaining between vaginal wall further improve the accuracy of diagnosis and the success rate of treatment.
For realizing the foregoing invention purpose, technical scheme that the present invention adopts is following:
A kind of laser doppler OCT vaginoscope system; Comprise colposcope and the cold light source main frame that is connected with this colposcope and shooting main frame; Said colposcope is provided with laser doppler data acquisition module and OCT data acquisition module; On said colposcope, also be connected with the data that said laser doppler data acquisition module is collected and carry out Doppler's processing host of analyzing and processing, on said colposcope, also be connected with the OCT processing host that the data that said OCT data acquisition module is collected are carried out analyzing and processing.
In the described laser doppler OCT vaginoscope system, its laser doppler data acquisition module comprises Laser emission end and laser pick-off end, and said OCT data acquisition module comprises prism, GRIN Lens and optical fiber tissue.
In the described laser doppler OCT vaginoscope system, its Doppler's processing host is connected a monitor or the shared monitor of split screen respectively with the OCT processing host.
In the described laser doppler OCT vaginoscope system; Its colposcope includes work end, cold light source joint, data connector, control module, instrument channel, intake tunnel and exhalant canal, the shared pipeline of said instrument channel, intake tunnel and exhalant canal; Said laser doppler data acquisition module and OCT data acquisition module are arranged on the colposcope; Specifically: on the first end of said work end, be provided with one and can stretch out the telescopic head that rotates with withdrawal and 360 degree, said laser doppler data acquisition module and OCT data acquisition module just are arranged in the telescopic head.
In the described laser doppler OCT vaginoscope system, the diameter of its telescopic head is smaller or equal to 3 millimeters.
In the described laser doppler OCT vaginoscope system, on the first end of said work end, also be provided with optical fibers, optical lens and Inlet and outlet water and the shared pipeline opening of instrument channel.
In the described laser doppler OCT vaginoscope system, the diameter of the pipeline opening that its Inlet and outlet water and instrument channel are shared is smaller or equal to 3 millimeters.
In the described laser doppler OCT vaginoscope system; It is 1.5～3.0 millimeters CCD optical lens that its optical lens adopts focal length, the imaging size of the CCD chip of this CCD optical lens smaller or equal to 1/4th inches, valid pixel more than or equal to 480,000, the angle of view is more than or equal to 100 degree.
In the described laser doppler OCT vaginoscope system, its work end is processed by hard material, and the first end of this hard work end is blunt type, the diameter of said work end smaller or equal to 15 millimeters, length greater than 200 millimeters.
Its principle of the present invention is at integrated laser doppler module of endoscopic technique and OCT module; Make the doctor can obtain the laser doppler image and the OCT image in patient affected part simultaneously through once performing the operation; Accomplish without any letup, reduce the diagnosis basis that damages and obtain enriching more.The laser doppler technology is to utilize the doppler principle of light wave; Utilize laser beam irradiation and write down the light of reflection, transmission, scattering and the data behind the reference light frequency modulation; Come accurately to survey the blood flow velocity and calculating blood flow flow of blood vessel, the laser doppler technology has than the more accurate certainty of measurement of doppler technique; The OCT module utilizes means of optical coherence tomography, carries out the fault imaging that resolution is carried out with micron level, obtains meticulous tomography pathological changes image.The vascular flow of blood vessel and tissue substance thereof is dynamically schemed between vaginal wall, and the tomography pathological changes image between tachogram and vaginal wall etc. are for doctor's diagnosis provides more accurate accurate data support.
Compared with prior art, the invention has the beneficial effects as follows:
The laser doppler measuring technique has than the more accurate characteristics of doppler technique, can obtain blood vessel accurate more dynamic image in top layer between vaginal wall; OCT techniques make use means of optical coherence tomography carries out the fault imaging that resolution is carried out with micron level, obtains meticulous tomography pathological changes image.Two images perhaps are simultaneously displayed in the display respectively, can improve the accuracy of diagnosis patient vagina pathological changes, assessment vagina function, further improve the accuracy rate and the success rate of operation.
Description of drawings
The picture that this description of drawings provided is used for auxiliary to further understanding of the present invention, constitutes the application's a part, does not constitute to improper qualification of the present invention, in the accompanying drawings:
Fig. 1 is a system structure sketch map of the present invention;
Fig. 2 is the colpomicroscopic structural representation of the present invention;
Fig. 3 is the local structure for amplifying sketch map of the first end of work of the present invention end.Diagram:
1, colposcope 2, cold light source main frame
3, shooting main frame 4, laser doppler processing host
5, OCT processing host 6, operation keyboard or handheld device
7, Doppler and OCT monitor 8, endoscope's monitor
11, work end 12, operating grip
13, data wire 14, instrument channel
15, intake tunnel 16, exhalant canal
17, control module 111, first end
1111, optical fibers 1112, optical lens
1113, shared pipeline opening 1114, the telescopic head of Inlet and outlet water and instrument channel
11141, Laser emission end 11142, laser pick-off end
11143, OCT data acquisition module 11144, micromotor
The specific embodiment
To combine accompanying drawing and practical implementation method to specify the present invention below, be used for explaining the present invention in schematic enforcement of the present invention and explanation, but not as to qualification of the present invention.
As shown in Figure 1; Laser doppler OCT vaginoscope system disclosed by the invention; Mainly comprise colposcope 1 and the cold light source main frame 2 that is connected with this colposcope 1, shooting main frame 3, laser doppler processing host 4, OCT processing host 5, also comprise operation keyboard or handheld device 6, Doppler and OCT monitor 7 and endoscope's monitor 8 these conventional input-output equipment certainly.
As shown in Figure 1, reduce cost in order to economize on resources, shared monitor-Doppler of laser doppler processing host and OCT processing host and OCT monitor 7 show through split screen in the present embodiment, can certainly use different monitors to be used for showing respectively.
Fig. 2 is the colpomicroscopic structural representation of the present invention, and is as shown in the figure, and it comprises work end 11, operating grip 12, data wire 13, instrument channel 14, intake tunnel 15, exhalant canal 16 and control module 17.Its work end 11 is processed by hard material, like materials such as medical stainless steels.For fear of the damage mucosal tissue, the first end of this hard work end is blunt type, and so-called blunt type is for there are stiff corner angle in head, such as circular, oval or other do not have the shape of stiff corner angle.For the ease of using, the diameter of work end 11 smaller or equal to 15 millimeters, length greater than 200 millimeters.
Fig. 3 is the local structure for amplifying sketch map of the first end 111 of work of the present invention end 11, and so-called first end promptly is the front end position, and its structure is specifically as shown in the figure:
This elder generation end 111 comprises optical fibers 1111 and is arranged at shared pipeline opening 1113 and the telescopic head 1114 of optical lens 1112, Inlet and outlet water and instrument channel on this optical fibers 1111 that this telescopic head 1114 comprises transparent outer cover and is installed in Laser emission end 11141, laser pick-off end 11142, OCT data acquisition module 11143 and the micromotor 11144 in the transparent outer cover.Wherein, Laser emission end 11141 constitutes the laser doppler data acquisition module with laser pick-off end 11142; Wherein, OCT data acquisition module 11143 comprises the conventional structures such as prism, GRIN Lens and optical fiber tissue that comprise; Wherein, telescopic head 1114 can stretch out the end face with withdrawal work end 11 under the effect of its micromotor 11144, also can at the uniform velocity rotate by 360 degree, observes with convenient.Wherein, use for ease, the diameter of telescopic head 1114 is smaller or equal to 3 millimeters, and shared pipeline opening 1113 diameters of Inlet and outlet water and apparatus are smaller or equal to 3 millimeters.Wherein, it is 1.5～3.0 millimeters CCD optical lens that optical lens 1112 adopts focal lengths, the imaging size of the CCD chip of this CCD optical lens smaller or equal to 1/4th inches, valid pixel more than or equal to 480,000, the angle of view is more than or equal to 100 degree.
The present invention with laser doppler module (laser doppler data acquisition module) and OCT module (OCT data acquisition module) under not interferential situation each other; Design Treatment through microminiaturization; Be integrated on the telescopic head 1114 on the first end 111 that is positioned at work end 11; This telescopic head 1114 can be released the end face realization work in addition of work end 11 through the transmission of micromachine 11144, and the inoperative stage is through the transmission of micromachine 11144; In 11 end faces of withdrawal work end, to make the usefulness of protection.
Operation keyboard among the present invention or handheld device 6, its function are that laser doppler main frame and OCT processing host are controlled, and scan mode and display mode etc. such as are switched at effect.
Laser doppler data acquisition module among the present invention and the combined effect of laser doppler processing host; The laser doppler processing host is carried out analyzing and processing to the data that the doppler data acquisition module collects; Can measure the microcirculation blood flow of blood vessel between vaginal wall; Whole microcirculatory perfusion amounts comprise that blood capillary, arteriole, venule and arteriovenous anastomosis prop up, and can monitor senior clinical datas such as microcirculatory hemodynamics variation through computational analysis.Described laser doppler processing host can carry powerful data base and powerful software test bag, to satisfy the different needs of the different purpose doctors of section.
OCT data acquisition module among the present invention and the combined effect of OCT processing host; Right vaginal wall phantom data that the OCT data acquisition module collected of OCT processing host and Treatment Analysis in addition; The faultage image that display resolution carries out with micron level, and output to the display demonstration.
Colposcope among the present invention has possessed general colpomicroscopic all optical observation functions; Among normal observation carries out or after; Can be through opening laser doppler processing host 4, OCT processing host 5 respectively or simultaneously; The laser doppler data acquisition module and the OCT data acquisition module that start on the telescopic head carry out laser doppler scanning and the observation of OCT tomoscan, and the telescopic head duration of work does not disturb the application of cystoscopic common function.
More than the technical scheme that the embodiment of the invention provided has been carried out detailed introduction; Used concrete example among this paper the principle and the embodiment of the embodiment of the invention are set forth, the explanation of above embodiment only is applicable to the principle that helps to understand the embodiment of the invention; Simultaneously, for one of ordinary skill in the art, according to the embodiment of the invention, the part that on the specific embodiment and range of application, all can change, in sum, this description should not be construed as limitation of the present invention.
Claims (9)
1. a laser doppler OCT vaginoscope system comprises colposcope and the cold light source main frame that is connected with this colposcope and shooting main frame, it is characterized in that:
Said colposcope is provided with laser doppler data acquisition module and OCT data acquisition module;
On said colposcope, also be connected with the data that said laser doppler data acquisition module is collected and carry out Doppler's processing host of analyzing and processing;
On said colposcope, also be connected with the data that said OCT data acquisition module is collected and carry out the OCT processing host of analyzing and processing.
2. laser doppler OCT vaginoscope system according to claim 1 is characterized in that:
Said laser doppler data acquisition module comprises Laser emission end and laser pick-off end, and said OCT data acquisition module comprises prism, GRIN Lens and optical fiber tissue.
3. laser doppler OCT vaginoscope system according to claim 1 is characterized in that:
Said Doppler's processing host is connected a monitor or the shared monitor of split screen respectively with the OCT processing host.
4. according to each described laser doppler OCT vaginoscope system of claim 1 to 3, it is characterized in that:
Said colposcope includes work end, cold light source joint, data connector, control module, instrument channel, intake tunnel and exhalant canal, the shared pipeline of said instrument channel, intake tunnel and exhalant canal;
Said laser doppler data acquisition module and OCT data acquisition module are arranged on the colposcope; Specifically: on the first end of said work end, be provided with one and can stretch out the telescopic head that rotates with withdrawal and 360 degree, said laser doppler data acquisition module and OCT data acquisition module just are arranged in the telescopic head.
5. laser doppler OCT vaginoscope system according to claim 4 is characterized in that:
The diameter of said telescopic head is smaller or equal to 3 millimeters.
6. laser doppler OCT vaginoscope system according to claim 4 is characterized in that:
On the first end of said work end, also be provided with optical fibers, optical lens and Inlet and outlet water and the shared pipeline opening of instrument channel.
7. laser doppler OCT vaginoscope system according to claim 6 is characterized in that:
The diameter of the pipeline opening that said Inlet and outlet water and instrument channel are shared is smaller or equal to 3 millimeters.
8. laser doppler OCT vaginoscope system according to claim 6 is characterized in that:
It is 1.5～3.0 millimeters CCD optical lens that said optical lens adopts focal length, the imaging size of the CCD chip of this CCD optical lens smaller or equal to 1/4th inches, valid pixel more than or equal to 480,000, the angle of view is more than or equal to 100 degree.
9. laser doppler OCT vaginoscope system according to claim 6 is characterized in that:
Said work end is processed by hard material, and the first end of this hard work end is blunt type;
The diameter of said work end smaller or equal to 15 millimeters, length greater than 200 millimeters.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2012100180594A CN102697460A (en) | 2012-01-18 | 2012-01-18 | Doppler laser optical coherence tomography (OCT) hard colposcope system |
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| CN2012100180594A CN102697460A (en) | 2012-01-18 | 2012-01-18 | Doppler laser optical coherence tomography (OCT) hard colposcope system |
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Citations (6)
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| CN2537345Y (en) * | 2002-02-05 | 2003-02-26 | 南开大学 | Double light beam laser Doppler blood flow instrument |
| US20070066871A1 (en) * | 2004-03-23 | 2007-03-22 | California Institute Of Technology Office Of Technology Transfer | Paired angled rotation scanning probes and methods of use |
| CN101686827A (en) * | 2007-01-19 | 2010-03-31 | 桑尼布鲁克健康科学中心 | Imaging probe with ultrasonic and optical imaging device of combination |
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| CN102008284A (en) * | 2010-12-30 | 2011-04-13 | 广州宝胆医疗器械科技有限公司 | Integrated color Doppler ultrasonic electronic colposcope system |
| CN202437068U (en) * | 2012-01-18 | 2012-09-19 | 广州宝胆医疗器械科技有限公司 | Doppler laser OCT (Optical Coherence Tomography) colposcope system |
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2012
- 2012-01-18 CN CN2012100180594A patent/CN102697460A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2537345Y (en) * | 2002-02-05 | 2003-02-26 | 南开大学 | Double light beam laser Doppler blood flow instrument |
| US20070066871A1 (en) * | 2004-03-23 | 2007-03-22 | California Institute Of Technology Office Of Technology Transfer | Paired angled rotation scanning probes and methods of use |
| CN101686827A (en) * | 2007-01-19 | 2010-03-31 | 桑尼布鲁克健康科学中心 | Imaging probe with ultrasonic and optical imaging device of combination |
| CN101785684A (en) * | 2010-01-27 | 2010-07-28 | 天津大学 | Ultrasonic endoscopic synthetic aperture imaging system and synthetic method of larger aperture |
| CN102008284A (en) * | 2010-12-30 | 2011-04-13 | 广州宝胆医疗器械科技有限公司 | Integrated color Doppler ultrasonic electronic colposcope system |
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Application publication date: 20121003 |