CN102694272B - A kind of MRI magnetic signal enhancement device - Google Patents
A kind of MRI magnetic signal enhancement device Download PDFInfo
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- CN102694272B CN102694272B CN201210133055.0A CN201210133055A CN102694272B CN 102694272 B CN102694272 B CN 102694272B CN 201210133055 A CN201210133055 A CN 201210133055A CN 102694272 B CN102694272 B CN 102694272B
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Abstract
The invention provides a kind of MRI magnetic signal enhancement device of accessories type, energy Contrast-enhanced MRI magnetic signal, improves MRI imaging effect, on the other hand, as a kind of passive device, has beneficial effect safe and reliable, easy to use on the one hand.
Description
[technical field]
The present invention relates to MRI technical field of imaging.
[background technology]
The principle of nulcear magnetic resonance (NMR) (MRI) imaging system utilizes coil to remove the radio wave pulses energy detecting nuclear spin absorption and launch, and this coil, as receiving coil, is being gone back simultaneously as transmitting coil sometimes.Under the help of radio wave pulses energy, Magnetic resonance imaging scanner can a very little point in position patient body, then determines that this is the tissue of which kind of type.This point may be the cube that a length of side only has half millimeter.Nuclear magnetic resonance imaging system can carry out point by point scanning to patient body, thus builds two dimension or the graphics of organization type.Afterwards, all information integration to together, are created a two dimensional image or threedimensional model by it.Maximum in nuclear magnetic resonance imaging system, be also simultaneously most important parts be exactly magnet.Magnet in nuclear magnetic resonance imaging system adopts the unit of tesla by name to weigh.The magnetic field intensity of the magnet nowadays used in magnetic resonance imaging device is between 0.5 to 2.0 teslas (or 5,000 to 20,000 Gauss).There is another kind of magnet in each nuclear magnetic resonance imaging system, be called gradient magnet.Three gradient magnets are had in magnetic resonance imaging machine device.Main magnet makes patient be in the magnetic field of stable a, high strength, and gradient magnet produces is a variable magnetic field.The remainder of nuclear magnetic resonance imaging system comprise a very powerful computer system, some under patient lies in scanner time by RF (radio frequency) impulse ejection to the equipment in patient body and other accessories many.Inner at the thorax cylinder of scanner, magnetic field is directly by the center of the pipeline of patient.This means if patient lies on the back in scanner, the proton of the hydrogen atom in its body will along foot or cephalad direction arrangement.The overwhelming majority in these protons can be compensated for each other---and that is, for each proton along the arrangement of foot direction, another proton all can be had to compensate for it towards cephalad direction arrangement.In each 1,000,000 proton, only have several can not mutually setoff.This sounds and few, but the hydrogen atom number only in body just is enough to depict high-quality image.
Magnetic resonance imaging machine device adopts the radio frequency pulse specific to hydrogen atom.The body region that will check is aimed in System guides pulse, and causes the proton uptake in this region to make them with the energy needed for different directions rotation or precession.This is NMR imaging device " resonance " part.Radio frequency pulse forces their (refer to unnecessary in each 1,000,000 proton a pair or two to unmatched proton) to rotate according to specific direction under characteristic frequency.The characteristic frequency causing resonance is called as Rameau that frequency, and this value draws according to wanting the magnetic field intensity of the particular organization of imaging and main field to calculate.Radio frequency pulse utilizes a coil to provide usually, and this coil is called transmitting coil (this generation coil is also magnetic signal receiving coil simultaneously usually).Magnetic resonance imaging machine device is furnished with different types of coil for the different parts of health: knee, shoulder, wrist, head, neck etc.These coils meet the profile of the body part accepting imaging usually, or at least during checking very near with the distance at these positions.Approximately at one time, three gradient magnets are started working.When opening and closing rapidly gradient magnet with certain particular form, their permutation and combination in main magnet make it can change main field in minimum subrange.This means that we accurately can select the region of wanted imaging, be referred to as in Magnetic resonance imaging " section ".Imagine that every sheet only has the piece of bread of a few millimeters thick---the section in Magnetic resonance imaging also can reach such precision.We can in any direction carry out " section " any position of health, make Magnetic resonance imaging have more advantage than other imaging techniques.This also means makes machine obtain image from another direction without the need to moving---and machine can utilize gradient magnet to complete various work.
When closing radio frequency pulse, the proton movement of hydrogen atom starts slowly (comparatively speaking) and returns their natural arrangement positions in magnetic field, and the additional energy that release stores.In this process, they can discharge a signal, and then coil can be caught this signal and is sent to computer system.System acceptance to the mathematical data being through conversion, these data form the figure that can be put on film by Fourier transform." imaging " part of nuclear magnetic resonance imaging system that Here it is.
The deficiency of existing magnetic resonance imaging device is: the necessary quite near-earth of receiving coil is close to detected part, to obtain the magnetic signal discharged by detected part, make troubles on the one hand the design of receiving coil, the different parts for health is needed to design different types of receiving coil, on the other hand, the manufacturing cost of equipment is added.
Existing magnetic resonance imaging device is according to the difference of field intensity, be divided into the low-field nuclear magnetic resonance imaging device being less than 1T, the high-field nuclear magnetic resonance imaging device of the midfield magnetic resonance imaging device of 1.5T and 3.0T or more, field intensity is higher, its manufacturing cost is higher, and imaging effect is also better.Middle-size and small-size medical institutions domestic at present due to fund, employing be low-field nuclear magnetic resonance imaging device, the MRI imaging effect of equipment in urgent need to be improved obtains more accurate and detailed diagnostic message.
[summary of the invention]
Technical problem to be solved by this invention, when not changing existing MRI equipment, improves MRI imaging effect, ensures equipment use fail safe simultaneously.
The technical scheme that the present invention realizes goal of the invention employing is, a kind of MRI magnetic signal enhancement device, be arranged between detected part and MRI magnetic signal receiving coil in order to Contrast-enhanced MRI magnetic signal, described MRI magnetic signal enhancement device comprises package casing and metamaterial flat, described metamaterial flat is the Meta Materials be made up of at least one deck metamaterial layer, described Meta Materials has negative magnetoconductivity under MRI magnetic signal operating frequency, described metamaterial flat is vertically fixed in described package casing, described package casing comprises the housing department that coordinates with metamaterial flat and the base portion with described housing department plane orthogonal, wherein, described metamaterial layer is made up of medium basic unit and man-made microstructure layer, described man-made microstructure layer is formed by multiple magnetic micro-structure array arrangement, and described magnetic micro-structure is that square spiral shell is around open ring structure, the resonance frequency of described Meta Materials is regulated by the number of turns adjusting coiling, by the adjustment of the resonance frequency to described Meta Materials, make described Meta Materials identical with MRI equipment operating frequency at negative magnetoconductivity condition lower frequency.
Preferably, balancing weight is provided with in described base portion.
Preferably, the junction of described housing department and described base portion is designed to fillet.
Preferably, described housing department is square plate structure.
Preferably, described base portion is two regions by described housing department, and the area in described two regions is unequal.
Preferably, in two regions of described base portion, the part that area is large is trapezoidal, and the part that area is little is concave shape.
Preferably, described package casing is PVC material.
Particularly, described medium basic unit is dielectric material, and described man-made microstructure layer is electric conducting material.
Particularly, described medium basic unit is epoxy resin fiberglass substrate, and described man-made microstructure layer is metallic copper material.
Particularly, the magnetic permeability of described Meta Materials is-1.
The invention provides a kind of MRI magnetic signal enhancement device of accessories type, energy Contrast-enhanced MRI magnetic signal, improves MRI imaging effect, on the other hand, as a kind of passive device, has beneficial effect safe and reliable, easy to use on the one hand.
[accompanying drawing explanation]
Fig. 1, the structure chart of MRI magnetic signal enhancement device.
Fig. 2, the outside drawing of MRI magnetic signal enhancement device.
Fig. 3, the structure chart of Meta Materials.
Fig. 4, square spiral shell gets around choma structure chart.
Fig. 5, the characteristic curve diagram of meta-material resonant frequency.
[embodiment]
Below in conjunction with drawings and Examples, the present invention is described in detail.
A kind of MRI magnetic signal enhancement device, be arranged between detected part and MRI magnetic signal receiving coil in order to Contrast-enhanced MRI magnetic signal, the structure chart of MRI magnetic signal enhancement device is referring to accompanying drawing 1, comprise package casing 1 and Meta Materials 2, package casing 1 comprises the housing department 11 that coordinates with Meta Materials 2 and the base portion 12 with housing department plane orthogonal, Meta Materials 2 is vertically fixed on housing department 11, is provided with balancing weight 13 in base portion 12.
As preferred embodiment, housing department 11 is designed to fillet structure with the junction of base portion 12, housing department 11 is square plate structure, base portion 12 is divided into two regions by housing department 11, and the area in two regions is unequal, wherein, the part that area is large is trapezoidal, the part that area is little is concave shape, and as shown in Figure 2, package casing 1 is all adopted as PVC material to the outside drawing of MRI magnetic signal enhancement device.
The structure chart of Meta Materials 2 is referring to accompanying drawing 3, by medium basic unit 21 and multiple array, the man-made microstructure 22 in medium basic unit 21 is formed, medium basic unit is epoxy resin fiberglass substrate, man-made microstructure is metallic copper material, the magnetic permeability of Meta Materials 2 under MRI magnetic signal operating frequency is-1, is described in detail below to Meta Materials 2.
Meta Materials refers to some artificial composite structures with the extraordinary physical property not available for natural material or composite material.By the structurally ordered design on the key physical yardstick of material, the restriction of some apparent natural law can be broken through, thus obtain the meta-materials function exceeding the intrinsic common character of nature.The character of Meta Materials and function mainly come from the structure of its inside but not form their material, and therefore, be design and synthesis Meta Materials, people have carried out a lot of research work.2000, the people such as the Smith of University of California pointed out that the metal wire of periodic arrangement and the composite construction of open loop resonator (SRR) can realize DIELECTRIC CONSTANT ε and magnetic permeability μ is negative two negative material simultaneously, also claim left-handed materials.They are again by achieving the two negative material of two dimension at printed circuit board (PCB) (PCB) upper making metal wire and SRR composite construction afterwards.Magnetic field is had to metal wire and the open loop resonator structure of response, be usually referred to as magnetic micro-structure.
The magnetic micro-structure of the present embodiment adopts spiral shell around open ring structure, accompanying drawing 4 be a kind of square spiral shell around open ring structure, circuit can be equivalent to lc circuit, annular metal cord equivalent inductance L, line capacitance equivalent capacity C, therefore, according to the formula of resonance frequency
after multiple coiling is carried out to micro-structural, the length of coil increases, increase inductance L equivalently, line capacitance C increases, thus reduce the resonance frequency of micro-structural, can be regulated the resonance frequency of micro-structural by the number of turns adjusting coiling, and then the resonance frequency of whole Meta Materials can be regulated.According to the characteristic curve diagram of meta-material resonant frequency, referring to accompanying drawing 5, as can be seen from the figure, within the scope of the band frequency after resonance peak, the magnetic permeability of Meta Materials is negative.Meta Materials magnetic permeability is that the resonance frequency of negative frequency band and Meta Materials is closely related, namely change along with the change of meta-material resonant frequency, therefore by the adjustment to meta-material resonant frequency, can obtain at the negative magnetoconductivity condition lower frequency Meta Materials identical with MRI equipment operating frequency.
The present embodiment is using above-mentioned Meta Materials as MRI magnetic signal enhancement device, MRI magnetic signal enhancement device is positioned between detected part and magnetic signal receiving coil, the magnetic signal sent due to detected part propagates with evanescent wave, and the propagation of evanescent wave is along with the increase of distance, there is the characteristic exponentially decayed, therefore existing magnetic signal receiving coil needs to be close to detected part, and need the profile of magnetic signal receiving coil to be designed to match with detected part shape, to strengthen the reception of magnetic signal, and then Contrast-enhanced MRI imaging effect, for medical diagnosis provides information more accurately.For making to have good impedance matching between MRI magnetic signal enhancement device and air, to reduce the reflection of energy, the present embodiment selects magnetic permeability to be that the Meta Materials of-1 is as MRI magnetic signal enhancement device.
The Meta Materials of negative magnetoconductivity is generally made up of medium substrate and the multiple magnetic micro-structures be arranged on medium substrate, medium substrate is dielectric material, magnetic micro-structure is electric conducting material, dielectric material can select thermosetting organic resin material, thermosetting organic resin fibre reinforced materials, thermoplasticity organic resin material, ceramic material, ceramic organic resin composite material etc., and electric conducting material generally selects metallic copper, silver, aluminium or gold.The preparation of Meta Materials generally adopts PCB manufacturing technology, as: on epoxy resin fiberglass plate, cover copper, prepare metallic copper magnetic micro-structure array by the method for printed circuit, obtain Meta Materials.
In above-described embodiment, simply show the magnetic micro-structure that a kind of square spiral shell gets around choma, as embodiment, concave shape spiral shell around split ring resonator, annular spiral shell gets around choma or polygon spiral shell gets around the Meta Materials that choma all can obtain having negative magnetoconductivity.
The MRI magnetic signal enhancement device of above-described embodiment, energy Contrast-enhanced MRI magnetic signal, improves MRI imaging effect, on the other hand, as a kind of passive device, has beneficial effect safe and reliable, easy to use on the one hand.
In the above-described embodiments, only to invention has been exemplary description, but those skilled in the art can carry out various amendment to the present invention without departing from the spirit and scope of the present invention after reading present patent application.
Claims (10)
1. a MRI magnetic signal enhancement device, be arranged between detected part and MRI magnetic signal receiving coil in order to Contrast-enhanced MRI magnetic signal, it is characterized in that: described MRI magnetic signal enhancement device comprises package casing and metamaterial flat, described metamaterial flat is the Meta Materials be made up of at least one deck metamaterial layer, described Meta Materials has negative magnetoconductivity under MRI magnetic signal operating frequency, described metamaterial flat is vertically fixed in described package casing, described package casing comprises the housing department that coordinates with metamaterial flat and the base portion with described housing department plane orthogonal
Wherein, described metamaterial layer is made up of medium basic unit and man-made microstructure layer, and described man-made microstructure layer is formed by multiple magnetic micro-structure array arrangement, and
Described magnetic micro-structure is that square spiral shell is around open ring structure, the resonance frequency of described Meta Materials is regulated by the number of turns adjusting coiling, by the adjustment of the resonance frequency to described Meta Materials, make described Meta Materials identical with MRI equipment operating frequency at negative magnetoconductivity condition lower frequency.
2. MRI magnetic signal enhancement device according to claim 1, is characterized in that: be provided with balancing weight in described base portion.
3. MRI magnetic signal enhancement device according to claim 1, is characterized in that: the junction of described housing department and described base portion is designed to fillet.
4. MRI magnetic signal enhancement device according to claim 1, is characterized in that: described housing department is square plate structure.
5. MRI magnetic signal enhancement device according to claim 1, is characterized in that: described base portion is two regions by described housing department, and the area in described two regions is unequal.
6. MRI magnetic signal enhancement device according to claim 5, is characterized in that: in two regions of described base portion, the part that area is large is trapezoidal, and the part that area is little is concave shape.
7. MRI magnetic signal enhancement device according to claim 5, is characterized in that: described package casing is PVC material.
8. the MRI magnetic signal enhancement device according to any one of claim 1 to 7, is characterized in that: described medium basic unit is dielectric material, and described man-made microstructure layer is electric conducting material.
9. MRI magnetic signal enhancement device according to claim 8, is characterized in that: described medium basic unit is epoxy resin fiberglass substrate, and described man-made microstructure layer is metallic copper material.
10. MRI magnetic signal enhancement device according to claim 8, is characterized in that: the magnetic permeability of described Meta Materials is-1.
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| WO2001071774A2 (en) * | 2000-03-17 | 2001-09-27 | The Regents Of The University Of California | Left handed composite media |
| CN101568849B (en) * | 2006-12-22 | 2013-07-24 | 皇家飞利浦电子股份有限公司 | RF coil for use in an mr imaging system |
| CN100553030C (en) * | 2007-11-02 | 2009-10-21 | 清华大学 | Electric field-tunable negative magnetic permeability part and preparation method based on ferroelectric ceramic grain |
| US20110204891A1 (en) * | 2009-06-25 | 2011-08-25 | Lockheed Martin Corporation | Direct magnetic imaging apparatus and method |
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| Multiple resonances in arrays of spiral resonators designed for magnetic resonance imaging;S.Massaoudi等;《Microwave and Optical technology Letters》;20080731;第50卷(第7期);第1945页第2栏第2段，第1949页第2栏第3段，及图1、4 * |
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Effective date of registration: 20210518 Address after: 2 / F, software building, No.9, Gaoxin Zhongyi Road, Nanshan District, Shenzhen City, Guangdong Province Patentee after: KUANG-CHI INSTITUTE OF ADVANCED TECHNOLOGY Address before: 18B, building a, CIC international business center, 1061 Xiangmei Road, Futian District, Shenzhen, Guangdong 518034 Patentee before: KUANG-CHI INNOVATIVE TECHNOLOGY Ltd. |
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