CN102687007B - 利用分层标准化切割的高处理量生物标志物分割 - Google Patents

利用分层标准化切割的高处理量生物标志物分割 Download PDF

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CN102687007B
CN102687007B CN201080051821.8A CN201080051821A CN102687007B CN 102687007 B CN102687007 B CN 102687007B CN 201080051821 A CN201080051821 A CN 201080051821A CN 102687007 B CN102687007 B CN 102687007B
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image
original image
hncut
segmentation
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CN102687007A (zh
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A·雅诺维茨克
S·钱德兰
A·马达布什
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Rutgers State University of New Jersey
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    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/10—Segmentation; Edge detection
    • G06T7/12—Edge-based segmentation
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00—Pattern recognition
    • G06F18/20—Analysing
    • G06F18/23—Clustering techniques
    • G06F18/232—Non-hierarchical techniques
    • G06F18/2323—Non-hierarchical techniques based on graph theory, e.g. minimum spanning trees [MST] or graph cuts
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/10—Segmentation; Edge detection
    • G06T7/162—Segmentation; Edge detection involving graph-based methods
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/70—Arrangements for image or video recognition or understanding using pattern recognition or machine learning
    • G06V10/762—Arrangements for image or video recognition or understanding using pattern recognition or machine learning using clustering, e.g. of similar faces in social networks
    • G06V10/7635—Arrangements for image or video recognition or understanding using pattern recognition or machine learning using clustering, e.g. of similar faces in social networks based on graphs, e.g. graph cuts or spectral clustering
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/695—Preprocessing, e.g. image segmentation
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10056—Microscopic image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/20—Special algorithmic details
    • G06T2207/20016—Hierarchical, coarse-to-fine, multiscale or multiresolution image processing; Pyramid transform
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30072—Microarray; Biochip, DNA array; Well plate

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  • Engineering & Computer Science (AREA)
  • Theoretical Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Data Mining & Analysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Artificial Intelligence (AREA)
  • Evolutionary Computation (AREA)
  • General Health & Medical Sciences (AREA)
  • Multimedia (AREA)
  • Computing Systems (AREA)
  • Software Systems (AREA)
  • Medical Informatics (AREA)
  • Discrete Mathematics (AREA)
  • Databases & Information Systems (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Image Analysis (AREA)
CN201080051821.8A 2009-09-18 2010-09-17 利用分层标准化切割的高处理量生物标志物分割 Expired - Fee Related CN102687007B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US27698609P 2009-09-18 2009-09-18
US61/276,986 2009-09-18
US29470310P 2010-01-13 2010-01-13
US61/294,703 2010-01-13
PCT/US2010/002536 WO2011034596A1 (en) 2009-09-18 2010-09-17 High-throughput biomarker segmentation utilizing hierarchical normalized cuts

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CN102687007A CN102687007A (zh) 2012-09-19
CN102687007B true CN102687007B (zh) 2015-07-22

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Country Status (6)

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US (1) US9111179B2 (enExample)
EP (1) EP2478356A1 (enExample)
CN (1) CN102687007B (enExample)
CA (1) CA2783935A1 (enExample)
IN (1) IN2012DN02374A (enExample)
WO (1) WO2011034596A1 (enExample)

Cited By (1)

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US12308096B2 (en) 2016-09-30 2025-05-20 Molecular Devices, Llc Computer device for detecting an optimal candidate compound and methods thereof

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CA2783935A1 (en) 2009-09-18 2011-03-24 Andrew Janowczyk High-throughput biomarker segmentation utilizing hierarchical normalized cuts
US9076068B2 (en) 2010-10-04 2015-07-07 Datacolor Holding Ag Method and apparatus for evaluating color in an image
CA2822502A1 (en) * 2010-10-11 2012-06-14 Woundmatrix, Inc. Wound management mobile image capture device
US20120113146A1 (en) * 2010-11-10 2012-05-10 Patrick Michael Virtue Methods, apparatus and articles of manufacture to combine segmentations of medical diagnostic images
JP5859771B2 (ja) * 2011-08-22 2016-02-16 ソニー株式会社 情報処理装置、情報処理システム情報処理方法及びプログラム
US9042630B2 (en) * 2011-10-26 2015-05-26 Definiens Ag Biomarker evaluation through image analysis
CN103063674B (zh) * 2012-12-26 2015-01-21 浙江大学 一种铜块的铜品位检测方法及其检测系统
WO2015021307A2 (en) * 2013-08-08 2015-02-12 Datacolor Holding Ag Method and apparatus for evaluating color in an image
WO2016107896A1 (en) * 2014-12-30 2016-07-07 Ventana Medical Systems, Inc. Systems and methods for co-expression analysis in immunoscore computation
US10873681B2 (en) 2016-02-08 2020-12-22 Imago Systems, Inc. System and method for the visualization and characterization of objects in images
US10424061B2 (en) 2016-03-02 2019-09-24 Flagship Biosciences, Inc. Method for assigning tissue normalization factors for digital image analysis
EP3460750B1 (en) * 2017-09-20 2020-03-25 DKFZ Deutsches Krebsforschungszentrum Method, system and computer program for computer-assisted evaluation of biomarkers in a tissue sample
JP7398073B2 (ja) * 2018-05-24 2023-12-14 ユニバーシティ オブ ピッツバーグ－オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション 空間マルチパラメータ細胞亜細胞画像データからの癌再発の予測
CN110211133B (zh) * 2019-05-27 2021-01-15 中国农业大学 带叶树木的安全防护策略获取方法、装置与电子设备
CN110728327B (zh) * 2019-10-18 2021-11-23 中国科学技术大学 一种具有可解释性的直推学习方法及系统
CN112669909B (zh) * 2020-12-30 2024-08-06 杭州博日科技股份有限公司 假阳性样本的排除方法、装置以及电子设备
CN115134339B (zh) * 2022-06-28 2024-07-02 京东方科技集团股份有限公司 媒体文件处理方法、装置及电子设备

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US20030224344A1 (en) * 2000-03-27 2003-12-04 Ron Shamir Method and system for clustering data
US20080033657A1 (en) * 2006-08-07 2008-02-07 General Electric Company System and methods for scoring images of a tissue micro array
CN101238487A (zh) * 2005-06-15 2008-08-06 组织诺斯替斯有限责任公司 分割白细胞的方法
US20080318800A1 (en) * 2005-08-05 2008-12-25 Genentech, Inc. Methods and compositions for detecting autoimmune disorders
CN101550441A (zh) * 2008-04-01 2009-10-07 博尔诚（北京）科技有限公司 含有生物标志物样本的高通量分析方法和样本库制备

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US20080059077A1 (en) 2006-06-12 2008-03-06 The Regents Of The University Of California Methods and systems of common motif and countermeasure discovery
US8204315B2 (en) 2006-10-18 2012-06-19 The Trustees Of The University Of Pennsylvania Systems and methods for classification of biological datasets
CA2783935A1 (en) 2009-09-18 2011-03-24 Andrew Janowczyk High-throughput biomarker segmentation utilizing hierarchical normalized cuts

Patent Citations (5)

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US20030224344A1 (en) * 2000-03-27 2003-12-04 Ron Shamir Method and system for clustering data
CN101238487A (zh) * 2005-06-15 2008-08-06 组织诺斯替斯有限责任公司 分割白细胞的方法
US20080318800A1 (en) * 2005-08-05 2008-12-25 Genentech, Inc. Methods and compositions for detecting autoimmune disorders
US20080033657A1 (en) * 2006-08-07 2008-02-07 General Electric Company System and methods for scoring images of a tissue micro array
CN101550441A (zh) * 2008-04-01 2009-10-07 博尔诚（北京）科技有限公司 含有生物标志物样本的高通量分析方法和样本库制备

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12308096B2 (en) 2016-09-30 2025-05-20 Molecular Devices, Llc Computer device for detecting an optimal candidate compound and methods thereof

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IN2012DN02374A (enExample) 2015-08-21
WO2011034596A1 (en) 2011-03-24
EP2478356A1 (en) 2012-07-25
US20120219206A1 (en) 2012-08-30
CN102687007A (zh) 2012-09-19
US9111179B2 (en) 2015-08-18
CA2783935A1 (en) 2011-03-24

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