CA2783935A1 - High-throughput biomarker segmentation utilizing hierarchical normalized cuts - Google Patents

High-throughput biomarker segmentation utilizing hierarchical normalized cuts Download PDF

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Publication number
CA2783935A1
CA2783935A1 CA2783935A CA2783935A CA2783935A1 CA 2783935 A1 CA2783935 A1 CA 2783935A1 CA 2783935 A CA2783935 A CA 2783935A CA 2783935 A CA2783935 A CA 2783935A CA 2783935 A1 CA2783935 A1 CA 2783935A1
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CA
Canada
Prior art keywords
data
image
original image
swatch
biomarker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2783935A
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English (en)
French (fr)
Inventor
Andrew Janowczyk
Sharat Chandran
Anant Madabhushi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rutgers State University of New Jersey
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Rutgers State University of New Jersey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rutgers State University of New Jersey filed Critical Rutgers State University of New Jersey
Publication of CA2783935A1 publication Critical patent/CA2783935A1/en
Abandoned legal-status Critical Current

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    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/10—Segmentation; Edge detection
    • G06T7/12—Edge-based segmentation
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00—Pattern recognition
    • G06F18/20—Analysing
    • G06F18/23—Clustering techniques
    • G06F18/232—Non-hierarchical techniques
    • G06F18/2323—Non-hierarchical techniques based on graph theory, e.g. minimum spanning trees [MST] or graph cuts
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/10—Segmentation; Edge detection
    • G06T7/162—Segmentation; Edge detection involving graph-based methods
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/70—Arrangements for image or video recognition or understanding using pattern recognition or machine learning
    • G06V10/762—Arrangements for image or video recognition or understanding using pattern recognition or machine learning using clustering, e.g. of similar faces in social networks
    • G06V10/7635—Arrangements for image or video recognition or understanding using pattern recognition or machine learning using clustering, e.g. of similar faces in social networks based on graphs, e.g. graph cuts or spectral clustering
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/695—Preprocessing, e.g. image segmentation
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10056—Microscopic image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/20—Special algorithmic details
    • G06T2207/20016—Hierarchical, coarse-to-fine, multiscale or multiresolution image processing; Pyramid transform
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30072—Microarray; Biochip, DNA array; Well plate

Landscapes

  • Engineering & Computer Science (AREA)
  • Theoretical Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Data Mining & Analysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Artificial Intelligence (AREA)
  • Evolutionary Computation (AREA)
  • General Health & Medical Sciences (AREA)
  • Multimedia (AREA)
  • Computing Systems (AREA)
  • Software Systems (AREA)
  • Medical Informatics (AREA)
  • Discrete Mathematics (AREA)
  • Databases & Information Systems (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Image Analysis (AREA)
CA2783935A 2009-09-18 2010-09-17 High-throughput biomarker segmentation utilizing hierarchical normalized cuts Abandoned CA2783935A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US27698609P 2009-09-18 2009-09-18
US61/276,986 2009-09-18
US29470310P 2010-01-13 2010-01-13
US61/294,703 2010-01-13
PCT/US2010/002536 WO2011034596A1 (en) 2009-09-18 2010-09-17 High-throughput biomarker segmentation utilizing hierarchical normalized cuts

Publications (1)

Publication Number Publication Date
CA2783935A1 true CA2783935A1 (en) 2011-03-24

Family

ID=43758945

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2783935A Abandoned CA2783935A1 (en) 2009-09-18 2010-09-17 High-throughput biomarker segmentation utilizing hierarchical normalized cuts

Country Status (6)

Country Link
US (1) US9111179B2 (enExample)
EP (1) EP2478356A1 (enExample)
CN (1) CN102687007B (enExample)
CA (1) CA2783935A1 (enExample)
IN (1) IN2012DN02374A (enExample)
WO (1) WO2011034596A1 (enExample)

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CN110211133A (zh) * 2019-05-27 2019-09-06 中国农业大学 带叶树木的安全防护策略获取方法、装置与电子设备

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IN2012DN02374A (enExample) 2009-09-18 2015-08-21 Univ Rutgers
US9076068B2 (en) 2010-10-04 2015-07-07 Datacolor Holding Ag Method and apparatus for evaluating color in an image
US20120120220A1 (en) * 2010-10-11 2012-05-17 Woundmatrix, Inc. Wound management mobile image capture device
US20120113146A1 (en) * 2010-11-10 2012-05-10 Patrick Michael Virtue Methods, apparatus and articles of manufacture to combine segmentations of medical diagnostic images
JP5859771B2 (ja) * 2011-08-22 2016-02-16 ソニー株式会社 情報処理装置、情報処理システム情報処理方法及びプログラム
US9042630B2 (en) * 2011-10-26 2015-05-26 Definiens Ag Biomarker evaluation through image analysis
CN103063674B (zh) * 2012-12-26 2015-01-21 浙江大学 一种铜块的铜品位检测方法及其检测系统
WO2015021307A2 (en) * 2013-08-08 2015-02-12 Datacolor Holding Ag Method and apparatus for evaluating color in an image
WO2016107896A1 (en) * 2014-12-30 2016-07-07 Ventana Medical Systems, Inc. Systems and methods for co-expression analysis in immunoscore computation
EP4273799A3 (en) 2016-02-08 2023-12-06 Imago Systems, Inc. System and method for the visualization and characterization of objects in images
WO2017151989A1 (en) * 2016-03-02 2017-09-08 Flagship Biosciences, Inc. Method for assigning tissue normalization factors for digital image analysis
EP3520004A2 (en) 2016-09-30 2019-08-07 GE Healthcare Bio-Sciences Corp. Computer device for detecting an optimal candidate compound and methods thereof
EP3460750B1 (en) * 2017-09-20 2020-03-25 DKFZ Deutsches Krebsforschungszentrum Method, system and computer program for computer-assisted evaluation of biomarkers in a tissue sample
CA3109279A1 (en) 2018-05-24 2019-11-28 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Predicting cancer recurrence from spatial multi-parameter cellular and subcellular imaging data.
CN110728327B (zh) * 2019-10-18 2021-11-23 中国科学技术大学 一种具有可解释性的直推学习方法及系统
CN112669909B (zh) * 2020-12-30 2024-08-06 杭州博日科技股份有限公司 假阳性样本的排除方法、装置以及电子设备
CN115134339B (zh) * 2022-06-28 2024-07-02 京东方科技集团股份有限公司 媒体文件处理方法、装置及电子设备

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030224344A1 (en) * 2000-03-27 2003-12-04 Ron Shamir Method and system for clustering data
AT501944B1 (de) * 2005-06-15 2007-06-15 Tissuegnostics Gmbh Verfahren zum segmentieren von leukozyten
CA2614455A1 (en) * 2005-08-05 2007-02-15 Genentech, Inc. Methods and compositions for detecting autoimmune disorders
US20080059077A1 (en) * 2006-06-12 2008-03-06 The Regents Of The University Of California Methods and systems of common motif and countermeasure discovery
US8060348B2 (en) 2006-08-07 2011-11-15 General Electric Company Systems for analyzing tissue samples
US8204315B2 (en) 2006-10-18 2012-06-19 The Trustees Of The University Of Pennsylvania Systems and methods for classification of biological datasets
CN101550441B (zh) * 2008-04-01 2011-11-23 博尔诚（北京）科技有限公司 含有生物标志物样本的高通量分析方法和样本库制备
IN2012DN02374A (enExample) 2009-09-18 2015-08-21 Univ Rutgers

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110211133A (zh) * 2019-05-27 2019-09-06 中国农业大学 带叶树木的安全防护策略获取方法、装置与电子设备
CN110211133B (zh) * 2019-05-27 2021-01-15 中国农业大学 带叶树木的安全防护策略获取方法、装置与电子设备

Also Published As

Publication number Publication date
WO2011034596A1 (en) 2011-03-24
CN102687007A (zh) 2012-09-19
EP2478356A1 (en) 2012-07-25
IN2012DN02374A (enExample) 2015-08-21
US9111179B2 (en) 2015-08-18
US20120219206A1 (en) 2012-08-30
CN102687007B (zh) 2015-07-22

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20150716

FZDE Discontinued

Effective date: 20170919