CN102680644B - 用于测定对嗅觉刺激物的情绪反应的方法 - Google Patents
用于测定对嗅觉刺激物的情绪反应的方法 Download PDFInfo
- Publication number
- CN102680644B CN102680644B CN201210042731.3A CN201210042731A CN102680644B CN 102680644 B CN102680644 B CN 102680644B CN 201210042731 A CN201210042731 A CN 201210042731A CN 102680644 B CN102680644 B CN 102680644B
- Authority
- CN
- China
- Prior art keywords
- fragrance
- smell
- experimenter
- subject
- recompense
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title claims abstract description 64
- 208000027534 Emotional disease Diseases 0.000 title abstract description 5
- 239000003205 fragrance Substances 0.000 claims abstract description 77
- 230000003291 dopaminomimetic effect Effects 0.000 claims abstract description 32
- 150000001875 compounds Chemical class 0.000 claims abstract description 20
- 238000002360 preparation method Methods 0.000 claims abstract description 12
- 238000012797 qualification Methods 0.000 claims abstract description 4
- 230000035943 smell Effects 0.000 claims description 54
- 210000004556 brain Anatomy 0.000 claims description 50
- 230000004913 activation Effects 0.000 claims description 27
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 claims description 14
- 210000002442 prefrontal cortex Anatomy 0.000 claims description 11
- 210000001259 mesencephalon Anatomy 0.000 claims description 10
- 235000013599 spices Nutrition 0.000 claims description 9
- 238000012935 Averaging Methods 0.000 claims description 7
- 230000009967 tasteless effect Effects 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 5
- 239000002537 cosmetic Substances 0.000 claims description 4
- 238000007865 diluting Methods 0.000 claims description 3
- 238000012216 screening Methods 0.000 claims description 2
- 238000002599 functional magnetic resonance imaging Methods 0.000 claims 2
- 230000000977 initiatory effect Effects 0.000 abstract description 5
- 238000012360 testing method Methods 0.000 description 19
- 238000002595 magnetic resonance imaging Methods 0.000 description 14
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 12
- 239000000463 material Substances 0.000 description 11
- 230000008786 sensory perception of smell Effects 0.000 description 10
- 210000004515 ventral tegmental area Anatomy 0.000 description 10
- 230000008569 process Effects 0.000 description 9
- 230000000694 effects Effects 0.000 description 8
- 238000002474 experimental method Methods 0.000 description 8
- 239000003921 oil Substances 0.000 description 8
- 235000019198 oils Nutrition 0.000 description 8
- 239000000796 flavoring agent Substances 0.000 description 7
- 235000019634 flavors Nutrition 0.000 description 7
- 241000220317 Rosa Species 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 6
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 6
- 238000003384 imaging method Methods 0.000 description 6
- 238000007619 statistical method Methods 0.000 description 6
- 230000000638 stimulation Effects 0.000 description 6
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 5
- DNIAPMSPPWPWGF-UHFFFAOYSA-N monopropylene glycol Natural products CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 5
- 235000013772 propylene glycol Nutrition 0.000 description 5
- 238000011160 research Methods 0.000 description 5
- 238000000540 analysis of variance Methods 0.000 description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 4
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 description 4
- 239000001301 oxygen Substances 0.000 description 4
- 229910052760 oxygen Inorganic materials 0.000 description 4
- 239000002304 perfume Substances 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 241001062472 Stokellia anisodon Species 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- 230000036651 mood Effects 0.000 description 3
- 210000001009 nucleus accumben Anatomy 0.000 description 3
- 230000004044 response Effects 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- 230000003068 static effect Effects 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
- 244000223014 Syzygium aromaticum Species 0.000 description 2
- 235000016639 Syzygium aromaticum Nutrition 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 238000012937 correction Methods 0.000 description 2
- 238000004821 distillation Methods 0.000 description 2
- 229960003638 dopamine Drugs 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 239000002979 fabric softener Substances 0.000 description 2
- 125000000524 functional group Chemical group 0.000 description 2
- 239000010648 geranium oil Substances 0.000 description 2
- 235000019717 geranium oil Nutrition 0.000 description 2
- -1 ketal Chemical class 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000001537 neural effect Effects 0.000 description 2
- 210000001331 nose Anatomy 0.000 description 2
- 230000007436 olfactory function Effects 0.000 description 2
- 208000011117 substance-related disease Diseases 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- INGWEZCOABYORO-UHFFFAOYSA-N 2-(furan-2-yl)-7-methyl-1h-1,8-naphthyridin-4-one Chemical compound N=1C2=NC(C)=CC=C2C(O)=CC=1C1=CC=CO1 INGWEZCOABYORO-UHFFFAOYSA-N 0.000 description 1
- WWJLCYHYLZZXBE-UHFFFAOYSA-N 5-chloro-1,3-dihydroindol-2-one Chemical compound ClC1=CC=C2NC(=O)CC2=C1 WWJLCYHYLZZXBE-UHFFFAOYSA-N 0.000 description 1
- 241000251468 Actinopterygii Species 0.000 description 1
- 244000099147 Ananas comosus Species 0.000 description 1
- 235000007119 Ananas comosus Nutrition 0.000 description 1
- 101100009524 Anas platyrhynchos HSD17B12 gene Proteins 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 241000522254 Cassia Species 0.000 description 1
- 206010009137 Chronic sinusitis Diseases 0.000 description 1
- 235000005979 Citrus limon Nutrition 0.000 description 1
- 244000131522 Citrus pyriformis Species 0.000 description 1
- 206010009244 Claustrophobia Diseases 0.000 description 1
- 240000007154 Coffea arabica Species 0.000 description 1
- 206010013654 Drug abuse Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000402754 Erythranthe moschata Species 0.000 description 1
- 241001539473 Euphoria Species 0.000 description 1
- 206010015535 Euphoric mood Diseases 0.000 description 1
- KGEKLUUHTZCSIP-UHFFFAOYSA-N Isobornyl acetate Natural products C1CC2(C)C(OC(=O)C)CC1C2(C)C KGEKLUUHTZCSIP-UHFFFAOYSA-N 0.000 description 1
- 235000019501 Lemon oil Nutrition 0.000 description 1
- 244000246386 Mentha pulegium Species 0.000 description 1
- 235000016257 Mentha pulegium Nutrition 0.000 description 1
- 235000004357 Mentha x piperita Nutrition 0.000 description 1
- LSDPWZHWYPCBBB-UHFFFAOYSA-N Methanethiol Chemical compound SC LSDPWZHWYPCBBB-UHFFFAOYSA-N 0.000 description 1
- 240000008790 Musa x paradisiaca Species 0.000 description 1
- 235000018290 Musa x paradisiaca Nutrition 0.000 description 1
- 208000000592 Nasal Polyps Diseases 0.000 description 1
- 206010029333 Neurosis Diseases 0.000 description 1
- 235000019502 Orange oil Nutrition 0.000 description 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 101100256975 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) SIP2 gene Proteins 0.000 description 1
- 101100203850 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) SPT2 gene Proteins 0.000 description 1
- 101100291461 Schizosaccharomyces pombe (strain 972 / ATCC 24843) spm2 gene Proteins 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- SEQDDYPDSLOBDC-UHFFFAOYSA-N Temazepam Chemical compound N=1C(O)C(=O)N(C)C2=CC=C(Cl)C=C2C=1C1=CC=CC=C1 SEQDDYPDSLOBDC-UHFFFAOYSA-N 0.000 description 1
- 240000002657 Thymus vulgaris Species 0.000 description 1
- 235000007303 Thymus vulgaris Nutrition 0.000 description 1
- DOOTYTYQINUNNV-UHFFFAOYSA-N Triethyl citrate Chemical compound CCOC(=O)CC(O)(C(=O)OCC)CC(=O)OCC DOOTYTYQINUNNV-UHFFFAOYSA-N 0.000 description 1
- 244000290333 Vanilla fragrans Species 0.000 description 1
- 235000009499 Vanilla fragrans Nutrition 0.000 description 1
- 235000012036 Vanilla tahitensis Nutrition 0.000 description 1
- 239000001940 [(1R,4S,6R)-1,7,7-trimethyl-6-bicyclo[2.2.1]heptanyl] acetate Substances 0.000 description 1
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 description 1
- 125000002777 acetyl group Chemical class [H]C([H])([H])C(*)=O 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 150000001299 aldehydes Chemical class 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 210000004727 amygdala Anatomy 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000001159 caudate nucleus Anatomy 0.000 description 1
- 239000010627 cedar oil Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 201000009151 chronic rhinitis Diseases 0.000 description 1
- 208000027157 chronic rhinosinusitis Diseases 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 239000012459 cleaning agent Substances 0.000 description 1
- 235000016213 coffee Nutrition 0.000 description 1
- 235000013353 coffee beverage Nutrition 0.000 description 1
- 230000019771 cognition Effects 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- 239000002781 deodorant agent Substances 0.000 description 1
- 108010002255 deoxyhemoglobin Proteins 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 206010013663 drug dependence Diseases 0.000 description 1
- 235000013601 eggs Nutrition 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 230000006397 emotional response Effects 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- TUEUDXZEBRMJEV-UWVGGRQHSA-N ethyl (1r,6s)-2,2,6-trimethylcyclohexane-1-carboxylate Chemical compound CCOC(=O)[C@@H]1[C@@H](C)CCCC1(C)C TUEUDXZEBRMJEV-UWVGGRQHSA-N 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 210000001061 forehead Anatomy 0.000 description 1
- WBJINCZRORDGAQ-UHFFFAOYSA-N formic acid ethyl ester Natural products CCOC=O WBJINCZRORDGAQ-UHFFFAOYSA-N 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 230000004886 head movement Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 210000001320 hippocampus Anatomy 0.000 description 1
- 235000001050 hortel pimenta Nutrition 0.000 description 1
- 238000013095 identification testing Methods 0.000 description 1
- 238000010191 image analysis Methods 0.000 description 1
- 150000002466 imines Chemical class 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 229910052738 indium Inorganic materials 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 210000000867 larynx Anatomy 0.000 description 1
- 239000010985 leather Substances 0.000 description 1
- 239000010501 lemon oil Substances 0.000 description 1
- 239000000696 magnetic material Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000008774 maternal effect Effects 0.000 description 1
- 239000001525 mentha piperita l. herb oil Substances 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 208000016366 nasal cavity polyp Diseases 0.000 description 1
- 210000002850 nasal mucosa Anatomy 0.000 description 1
- 210000001577 neostriatum Anatomy 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
- 201000001119 neuropathy Diseases 0.000 description 1
- 230000007823 neuropathy Effects 0.000 description 1
- 208000015238 neurotic disease Diseases 0.000 description 1
- 239000002858 neurotransmitter agent Substances 0.000 description 1
- 150000002825 nitriles Chemical class 0.000 description 1
- 239000010502 orange oil Substances 0.000 description 1
- 230000002450 orbitofrontal effect Effects 0.000 description 1
- 150000002923 oximes Chemical class 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 235000019477 peppermint oil Nutrition 0.000 description 1
- 208000033808 peripheral neuropathy Diseases 0.000 description 1
- 238000012831 peritoneal equilibrium test Methods 0.000 description 1
- 208000019899 phobic disease Diseases 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 238000012636 positron electron tomography Methods 0.000 description 1
- 238000012877 positron emission topography Methods 0.000 description 1
- 238000012805 post-processing Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 229940001470 psychoactive drug Drugs 0.000 description 1
- 239000004089 psychotropic agent Substances 0.000 description 1
- 210000002637 putamen Anatomy 0.000 description 1
- 230000008707 rearrangement Effects 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 206010039083 rhinitis Diseases 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 239000010666 rose oil Substances 0.000 description 1
- 235000019719 rose oil Nutrition 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 230000001932 seasonal effect Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 238000002603 single-photon emission computed tomography Methods 0.000 description 1
- 229940061368 sonata Drugs 0.000 description 1
- 238000000528 statistical test Methods 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 230000000475 sunscreen effect Effects 0.000 description 1
- 239000000516 sunscreening agent Substances 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 230000009897 systematic effect Effects 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 210000003051 thermoreceptor Anatomy 0.000 description 1
- 108091008689 thermoreceptors Proteins 0.000 description 1
- 230000033912 thigmotaxis Effects 0.000 description 1
- 125000005323 thioketone group Chemical group 0.000 description 1
- 239000001585 thymus vulgaris Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- QQJLHRRUATVHED-UHFFFAOYSA-N tramazoline Chemical compound N1CCN=C1NC1=CC=CC2=C1CCCC2 QQJLHRRUATVHED-UHFFFAOYSA-N 0.000 description 1
- 229960001262 tramazoline Drugs 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 description 1
- 235000013769 triethyl citrate Nutrition 0.000 description 1
- 239000001069 triethyl citrate Substances 0.000 description 1
- 230000002618 waking effect Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/4806—Functional imaging of brain activation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- Radiology & Medical Imaging (AREA)
- High Energy & Nuclear Physics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Neurology (AREA)
- Pathology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Detergent Compositions (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11305196.5A EP2492705B1 (fr) | 2011-02-24 | 2011-02-24 | Procédé d'identification par IRM fonctionnelle de stimulus olfactifs du système de récompense dopaminergique |
| EP11305196.5 | 2011-02-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102680644A CN102680644A (zh) | 2012-09-19 |
| CN102680644B true CN102680644B (zh) | 2016-05-11 |
Family
ID=44170278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210042731.3A Expired - Fee Related CN102680644B (zh) | 2011-02-24 | 2012-02-23 | 用于测定对嗅觉刺激物的情绪反应的方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10042023B2 (fr) |
| EP (1) | EP2492705B1 (fr) |
| JP (1) | JP2012177112A (fr) |
| CN (1) | CN102680644B (fr) |
| BR (1) | BR102012003941A2 (fr) |
| ES (1) | ES2563781T3 (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9842001B2 (en) * | 2012-06-27 | 2017-12-12 | International Business Machines Corporation | System level acceleration server |
| WO2014043149A1 (fr) * | 2012-09-12 | 2014-03-20 | The Schepens Eye Research Institute, Inc. | Mesure de l'acquisition de données au moyen d'un système de rappel libre |
| WO2016009300A1 (fr) * | 2014-07-15 | 2016-01-21 | Koninklijke Philips N.V. | Test statistique de données d'imagerie comprenant une normalisation stéréotaxique avec une image modèle personnalisée |
| KR101630747B1 (ko) * | 2014-10-31 | 2016-06-15 | 건국대학교 글로컬산학협력단 | 후각 기능 평가 방법 및 장치 |
| BR102014032403B1 (pt) * | 2014-12-23 | 2023-05-09 | União Brasileira De Educação E Assistência | Sistema para estímulo olfativo e processo de detecção de sinais de resposta à estímulos olfativos |
| US11013426B2 (en) | 2015-01-23 | 2021-05-25 | Auburn University | System and method of functional MRI of the neural system in conscious unrestrained dogs |
| JP6838135B2 (ja) | 2016-07-21 | 2021-03-03 | マジック リープ， インコーポレイテッドＭａｇｉｃ Ｌｅａｐ，Ｉｎｃ． | ユーザの感情状態を用いて仮想画像生成システムを制御するための技術 |
| ES2951002T3 (es) | 2016-12-21 | 2023-10-17 | Firmenich & Cie | Procedimiento de IRMf para determinar patrones de activación cerebral en respuesta a sensaciones provocadas por olores |
| US10595735B2 (en) | 2018-01-12 | 2020-03-24 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for personalized clinical applications of accelerated theta-burst stimulation |
| EP4119968A1 (fr) * | 2021-07-15 | 2023-01-18 | Takasago International Corporation | Procédé de mesure de la réponse à des stimulus olfactifs |
| FR3129072B1 (fr) | 2021-11-17 | 2023-09-29 | Robertet Sa | Procédé de caractérisation d’une stimulation olfactive |
| CN115474555B (zh) * | 2022-09-28 | 2023-06-09 | 重庆医科大学附属儿童医院 | 一种实验动物嗅觉行为监测装置及方法 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6325475B1 (en) * | 1996-09-06 | 2001-12-04 | Microfab Technologies Inc. | Devices for presenting airborne materials to the nose |
| WO2006093513A9 (fr) * | 2004-06-14 | 2006-11-02 | Cephos Corp | Paradigmes de questions et de controle de detection d'un etat de deception par mesure de l'activite cerebrale |
| CN101351386A (zh) * | 2005-12-27 | 2009-01-21 | 金伯利-克拉克环球有限公司 | 具有使用者可选香味的包装好的消费产品 |
| CN101512574A (zh) * | 2006-09-07 | 2009-08-19 | 宝洁公司 | 用于测量情绪响应和选择偏好的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6711430B1 (en) * | 1998-10-09 | 2004-03-23 | Insight Neuroimaging Systems, Inc. | Method and apparatus for performing neuroimaging |
| WO2007001904A2 (fr) * | 2005-06-21 | 2007-01-04 | The Procter & Gamble Company | Compositions cosmetiques contenant des alpha-glucanes et/ou des beta-glucanes |
| US20080027575A1 (en) * | 2006-04-21 | 2008-01-31 | Jones Stevan D | Modeling systems for health and beauty consumer goods |
| US20080065468A1 (en) * | 2006-09-07 | 2008-03-13 | Charles John Berg | Methods for Measuring Emotive Response and Selection Preference |
| US8255267B2 (en) * | 2007-07-13 | 2012-08-28 | Wahrheit, Llc | System and method for determining relative preferences |
| US20090318773A1 (en) * | 2008-06-24 | 2009-12-24 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Involuntary-response-dependent consequences |
| US20110028859A1 (en) * | 2009-07-31 | 2011-02-03 | Neuropace, Inc. | Methods, Systems and Devices for Monitoring a Target in a Neural System and Facilitating or Controlling a Cell Therapy |
-
2011
- 2011-02-24 EP EP11305196.5A patent/EP2492705B1/fr active Active
- 2011-02-24 ES ES11305196.5T patent/ES2563781T3/es active Active
-
2012
- 2012-02-23 CN CN201210042731.3A patent/CN102680644B/zh not_active Expired - Fee Related
- 2012-02-23 US US13/403,612 patent/US10042023B2/en active Active
- 2012-02-23 BR BRBR102012003941-9A patent/BR102012003941A2/pt not_active IP Right Cessation
- 2012-02-23 JP JP2012037592A patent/JP2012177112A/ja active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6325475B1 (en) * | 1996-09-06 | 2001-12-04 | Microfab Technologies Inc. | Devices for presenting airborne materials to the nose |
| WO2006093513A9 (fr) * | 2004-06-14 | 2006-11-02 | Cephos Corp | Paradigmes de questions et de controle de detection d'un etat de deception par mesure de l'activite cerebrale |
| CN101351386A (zh) * | 2005-12-27 | 2009-01-21 | 金伯利-克拉克环球有限公司 | 具有使用者可选香味的包装好的消费产品 |
| CN101512574A (zh) * | 2006-09-07 | 2009-08-19 | 宝洁公司 | 用于测量情绪响应和选择偏好的方法 |
Non-Patent Citations (5)
| Title |
|---|
| Appetitive and Aversive Olfactory Learning in Humans Studied Using Event-Related Functional Magnetic Resonance Imaging;Jay A等;《The Journal of Neuroscience》;20021215;第22卷(第24期);第10829-10837页 * |
| HC Breiter等.Functional magnetic resonance imaging of Brain Reward Circuitry in the Human.《Annals of the New York Academy of Science》.1996,第1877卷 * |
| Olfactory activity in the human brain indentified by fMRI;Smejkal V等;《Bratisl Lek Listy》;20031231;第104卷(第6期);第184-188页 * |
| Roland Popp等.Olfactometry in fMRI studies:odor presentation using nasal continuous positive airway pressure.《ACTA NEUROBIOLOGIAE EXPERIMENTALIS》.2004,第64卷 * |
| Veronique Bragulat等.Food-Related Odor Probes of Brain Reward Circuits During Hunger: A Pilot fMRI Study.《BEHAVIOR AND PSYCHOLOGY》.2010,第18卷(第8期), * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2492705B1 (fr) | 2015-12-30 |
| ES2563781T3 (es) | 2016-03-16 |
| JP2012177112A (ja) | 2012-09-13 |
| EP2492705A1 (fr) | 2012-08-29 |
| CN102680644A (zh) | 2012-09-19 |
| BR102012003941A2 (pt) | 2013-07-23 |
| US10042023B2 (en) | 2018-08-07 |
| US20120220857A1 (en) | 2012-08-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102680644B (zh) | 用于测定对嗅觉刺激物的情绪反应的方法 | |
| Wang et al. | Dimensions of experience: exploring the heterogeneity of the wandering mind | |
| Zuo et al. | Network centrality in the human functional connectome | |
| Weiss et al. | Human olfaction without apparent olfactory bulbs | |
| Herold et al. | The contribution of functional magnetic resonance imaging to the understanding of the effects of acute physical exercise on cognition | |
| Gottfried et al. | Dissociable codes of odor quality and odorant structure in human piriform cortex | |
| Kenning et al. | NeuroEconomics: An overview from an economic perspective | |
| Lyoo et al. | Frontal lobe gray matter density decreases in bipolar I disorder | |
| Fusar-Poli et al. | Laterality effect on emotional faces processing: ALE meta-analysis of evidence | |
| Jongen et al. | An investigation of facial emotion recognition impairments in alexithymia and its neural correlates | |
| O’Neill et al. | Dysregulation between emotion and theory of mind networks in borderline personality disorder | |
| Reynolds et al. | Cortical source localization of infant cognition | |
| Kumar et al. | Oxytocin affects the connectivity of the precuneus and the amygdala: a randomized, double-blinded, placebo-controlled neuroimaging trial | |
| Xin et al. | Oxytocin modulates the intrinsic dynamics between attention-related large-scale networks | |
| Zhu et al. | Brain structure, cardiorespiratory fitness, and executive control changes after a 9-week exercise intervention in young adults: a randomized controlled trial | |
| Ihnen et al. | Lack of generalizability of sex differences in the fMRI BOLD activity associated with language processing in adults | |
| Fernández et al. | Increased occipital delta dipole density in major depressive disorder determined by magnetoencephalography | |
| Andrews et al. | Extensive connections of the canine olfactory pathway revealed by tractography and dissection | |
| Gottfried | Structural and functional imaging of the human olfactory system | |
| Donoshita et al. | Assessment of olfactory information in the human brain using 7-Tesla functional magnetic resonance imaging | |
| Ioachim et al. | Coordinated human brainstem and spinal cord networks during the expectation of pain have elements unique from resting-state effects | |
| Filiz et al. | Olfactory bulb volume and cortical thickness evolve during sommelier training | |
| Hermosillo et al. | A precision functional atlas of network probabilities and individual-specific network topography | |
| Suen et al. | Effective connectivity in the human brain for sour taste, retronasal smell, and combined flavour | |
| Zhao et al. | Hub patterns-based detection of dynamic functional network metastates in resting state: A test-retest analysis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160511 Termination date: 20190223 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |