CN102670871B - Traditional Chinese medicine combination for rheumatism and rheumatoid arthritis and application thereof - Google Patents
Traditional Chinese medicine combination for rheumatism and rheumatoid arthritis and application thereof Download PDFInfo
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Abstract
The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine combination for rheumatism and rheumatoid arthritis, which is prepared with the following Chinese herbal medicines: 20 to 50 grams of whiteback thundergodvine, 6 to 12 grams of suberect spatholobus stem, 5 to 8 grams of rehmannia root, 5 to 8 grams of epimedium herb, 1 to 5 grams of glycyrrhiza and 3 to 7 grams of saffron crocus. The traditional Chinese medicine combination is used for treating rheumatism and rheumatoid arthritis. The traditional Chinese medicine combination has the characteristics of rapid effect, safety and no toxic and side effects.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine composition and application thereof.
Background technology
Arthritis general reference occurs in the inflammatory diseases of human synovial and surrounding tissue thereof, can be divided into tens of kinds.Clinical manifestation be joint red, swollen, hot, bitterly, dysfunction and joint deformity, severe patient cause joint disabled, affect patients ' life quality.The arthritic cause of disease is complicated, mainly relevant with the factor such as inflammation, autoimmune response, infection, metabolism disorder, wound, degeneration.Clinical common arthritis mainly comprises following several: the joint manifestations of rheumatism, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gouty arthritis, reactive arthritis, infective arthritis, traumatic arthritis, psoriatic arthritis, enteropathic arthritis, other systemic diseases comprises systemic lupus erythematosus (sle), tumor, hematopathy etc.
Rheumatic arthritis (rheumatoid arthritis) is a kind of common acute or chronic ICT, can recurrent exerbation involve heart, clinical with joint and muscle migrans miserable, heavily work, pain is for feature.The chronic generalized autoimmune disease of rheumatoid arthritis (rheumatoid arthritis) to be a kind of with articular synovitis be feature, the lasting recurrent exerbation of synovitis, can cause the destruction of intraarticular cartilage and bone, joint function disturbance, even maimed.Vasculitis pathological changes involves each organ of whole body, therefore primary disease is also called rheumatoid disease.
At present, the means of clinical treatment rheumatism, rheumatoid arthritis mainly contain: naturopathy, main method such as employing various electrotherapy and acupuncture etc., and effect is not clearly; Drug therapy, be exactly mainly take non-steroidal antiinflammatory drugs (NSAIDs), glucocorticoid (Gs), improve the state of an illness and act on antirheumatic (DMARDs), plant amedica, biological preparation etc. slowly, clinical display often produces drug resistance, and can not radical curing of disease, and Western medicine toxic and side effects be larger.The traditional Chinese medical science often biased toward wind and cold to the understanding of primary disease and to wet the stasis of blood in the past, adopted the effect for the treatment of by Chinese herbs unsatisfactory.
Summary of the invention
For the deficiency that above-mentioned prior art exists, for reaching the object of curing rheumatism, rheumatoid arthritis more rapidly and effectively, inventor aims to provide a kind of Chinese medicine composition of rapid-action, treatment rheumatism that treatment time is short, rheumatoid arthritis.
Particularly, inventor provides following technical scheme:
A kind of rheumatism, rheumatoid Chinese medicine composition are made up of the traditional Chinese medicinal material raw materials of following weight:
Herba Begoniae Yunnanensis 20-50 gram, Caulis Spatholobi 6-12 gram, Radix Rehmanniae 5-8 gram, Herba Epimedii 5-8 gram, Radix Glycyrrhizae 1-5 gram, Stigma Croci 3-7 gram.
As preferably, the Herba Begoniae Yunnanensis described in the present invention is Tripterygium hypoglaucum.
As preferably, the Chinese medicine composition described in the present invention is prepared as follows:
Caulis Spatholobi, the Radix Rehmanniae, Herba Epimedii, Radix Glycyrrhizae, Stigma Croci, add water by proportioning and boil 1-2 hour, after leaching medicine juice, in medicine juice, add Herba Begoniae Yunnanensis soak more than 30 minutes, pull out after abundant absorption medicine juice, be placed on that temperature is 20-25 DEG C, relative air humidity is under the environment of 50-58%, go mouldy under lucifuge, ventilation condition more than 48 hours, joining concentration is again soak 10-20 minute in the hydroxypropyl aqueous solution of 5%, finally dries the Herba Begoniae Yunnanensis obtaining handling well.
Present invention also offers the application of above-mentioned a kind of Chinese medicine composition on preparation treatment rheumatism, medicine for treating rheumatoid arthritis.
Formula of the present invention, from tcm family, experienced by the clinical effectiveness checking of several generations.Be principal agent with Tripterygium hypoglaucum in formula, be aided with other Chinese crude drugs, follow meridian tropism principle, use medicine coordinate mutually into usefulness, selected multi-flavor has the Chinese crude drug of the effects such as expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, heat-clearing and toxic substances removing, promoting the circulation of QI to relieve pain, blood circulation promoting and blood stasis dispelling, rational proportion, and be equipped with suitable Chinese medicine processing method, obtain the treatment rheumatism of above-mentioned formula, the Chinese medicine composition of rheumatoid arthritis.
In Chinese medicine formula of the present invention:
Tripterygium hypoglaucum, has expelling wind and removing dampness, promoting blood circulation and hemostasis, relieving rigidity of muscles and knitting bone, removing toxic substances disinsection efficiency, main air pain of dampness syndrome.
Caulis Spatholobi, have enrich blood, invigorate blood circulation, effect of dredging collateral.
The Radix Rehmanniae, the Radix Rehmanniae is also Radix Rehmanniae, effect that Radix Rehmanniae has clearing away heat and cooling blood, tonifying YIN promotes the production of body fluid.
Herba Epimedii, has effect of kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.
Radix Glycyrrhizae is a kind of tonification Chinese herbal medicine, has the effects such as heat-clearing and toxic substances removing, expelling phlegm for arresting cough, gastral cavity abdomen.
Stigma Croci, has calmness, eliminates the phlegm, spasmolysis, for the treatment of gastropathy, regulating menstruation, measles, heating, jaundice, hepatosplenomegaly etc.
The relevant regulations that the Chinese crude drug that ingredients in the present invention meets the Pharmacopoeia of the People's Republic of China of version in 2005 is concocted.
Chinese medicine composition of the present invention uses as follows: the Herba Begoniae Yunnanensis decocting system namely handled well by the Chinese medicine composition of preparation, and the decoction obtained is oral, one day potion decoction, within eight days, is one-period, and three cycles are a course for the treatment of.
Compared with prior art, the present invention has the following advantages:
Rheumatoid arthritis Chinese medicine composition of the present invention, has sufficient raw, prepares feature simple, easy to use, simultaneously short treating period (general 5-8 days takes effect, and symptom was obviously alleviated in 24 days).Clinical effective rate reaches more than 99%, and safety does not have toxic and side effects.
Detailed description of the invention
Below in conjunction with embodiment, further illustrate content of the present invention.Should be appreciated that enforcement of the present invention is not limited to the following examples, any pro forma accommodation make the present invention and/or change all will fall into scope.
In the present invention, if not refer in particular to, all parts, percentage ratio are unit of weight, and all equipment and raw material etc. all can be buied from market or the industry is conventional.Method in following embodiment, if no special instructions, is the conventional method of this area.
embodiment 1:
A kind of rheumatism, rheumatoid Chinese medicine composition, be made up of the traditional Chinese medicinal material raw materials of following weight:
Tripterygium hypoglaucum 20 grams, Caulis Spatholobi 6 grams, 5 grams, the Radix Rehmanniae, Herba Epimedii 5 grams, 1 gram, Radix Glycyrrhizae, Stigma Croci 3 grams.
Caulis Spatholobi, the Radix Rehmanniae, Herba Epimedii, Radix Glycyrrhizae, Stigma Croci, add water by proportioning and boil 1 hour, after leaching medicine juice, in medicine juice, add Herba Begoniae Yunnanensis soak 30 minutes, pull out after abundant absorption medicine juice, be placed on that temperature is 25 DEG C, relative air humidity is under the environment of 55%, go mouldy under lucifuge, ventilation condition 48 hours, joining concentration is again soak 10 minutes in the hydroxypropyl aqueous solution of 5%, finally takes the Tripterygium hypoglaucum of drying in drying room and obtaining handling well.
embodiment 2
A kind of rheumatism, rheumatoid Chinese medicine composition, be made up of the traditional Chinese medicinal material raw materials of following weight:
Tripterygium hypoglaucum 50 grams, Caulis Spatholobi 12 grams, 8 grams, the Radix Rehmanniae, Herba Epimedii 8 grams, 5 grams, Radix Glycyrrhizae, Stigma Croci 7 grams.
Caulis Spatholobi, the Radix Rehmanniae, Herba Epimedii, Radix Glycyrrhizae, Stigma Croci, add water by proportioning and boil 2 hours, after leaching medicine juice, in medicine juice, add Herba Begoniae Yunnanensis soak 35 minutes, pull out after abundant absorption medicine juice, be placed on that temperature is 20 DEG C, relative air humidity is under the environment of 57%, go mouldy under lucifuge, ventilation condition 48 hours, joining concentration is again soak 20 minutes in the hydroxypropyl aqueous solution of 5%, finally takes the Tripterygium hypoglaucum of drying in drying room and obtaining handling well.
embodiment 3
A kind of rheumatism, rheumatoid Chinese medicine composition, be made up of the traditional Chinese medicinal material raw materials of following weight:
Tripterygium hypoglaucum 30 grams, Caulis Spatholobi 8 grams, 7 grams, the Radix Rehmanniae, Herba Epimedii 6 grams, 3 grams, Radix Glycyrrhizae, Stigma Croci 6 grams.
Caulis Spatholobi, the Radix Rehmanniae, Herba Epimedii, Radix Glycyrrhizae, Stigma Croci, add water by proportioning and boil 1.5 hours, after leaching medicine juice, in medicine juice, add Herba Begoniae Yunnanensis soak 30 minutes, pull out after abundant absorption medicine juice, be placed on that temperature is 22 DEG C, relative air humidity is under the environment of 50%, go mouldy under lucifuge, ventilation condition 48 hours, joining concentration is again soak 15 minutes in the hydroxypropyl aqueous solution of 5%, finally takes the Tripterygium hypoglaucum of drying in drying room and obtaining handling well.
embodiment 4
A kind of rheumatism, rheumatoid Chinese medicine composition, be made up of the traditional Chinese medicinal material raw materials of following weight:
Tripterygium hypoglaucum 40 grams, Caulis Spatholobi 10 grams, 8 grams, the Radix Rehmanniae, Herba Epimedii 5 grams, 4 grams, Radix Glycyrrhizae, Stigma Croci 3 grams.
Caulis Spatholobi, the Radix Rehmanniae, Herba Epimedii, Radix Glycyrrhizae, Stigma Croci, add water by proportioning and boil 1 hour, after leaching medicine juice, in medicine juice, add Herba Begoniae Yunnanensis soak 30 minutes, pull out after abundant absorption medicine juice, be placed on that temperature is 25 DEG C, relative air humidity is under the environment of 58%, go mouldy under lucifuge, ventilation condition 48 hours, joining concentration is again soak 20 minutes in the hydroxypropyl aqueous solution of 5%, finally takes the Tripterygium hypoglaucum of drying in drying room and obtaining handling well.
application examples
The rheumatism provided in formula of the present invention, rheumatoid Chinese medicine composition, clinical practice shows that therapeutic effect does not have obvious difference, below application examples be all Chinese medicine composition prepared by the embodiment 1-4 got arbitrarily.
Rheumatism provided by the invention, rheumatoid Chinese medicine composition, during use, by the Tripterygium hypoglaucum decocting system handled well, the decoction obtained is oral, one day potion decoction, within eight days, is one-period, and three cycles are a course for the treatment of.Chinese medicine composition of the present invention is through the clinical verification of decades, and effective percentage reaches more than 99%, enumerates several exemplary below and is explained its result of use.
application examples 1
Patient, Wang Wenzheng, 69 years old, man.Suffer from rheumatoid arthritis, the course of disease has twenty or thirty year, but does not commit excesses always, finger pain when being exactly one's late 30s, checks and suffers from rheumatoid arthritis, but also how not violate so for many years, exactly in July, 2011 finger, lower limb, wrist start to swell, take methotrexate before, start some effect, the time has been grown and there just has not been effect, stair activity needs to assist in, be slow in action, rheumatoid factor 267, erythrocyte sedimentation rate 72.After using 2 courses for the treatment of of Chinese medicine composition of the present invention, action and ordinary person are as good as, and rheumatoid factor 37, erythrocyte sedimentation rate is close to normal value 20.
application examples 2
Patient, Gao Yanxiang, 45 years old, female, people from Changchun City.The state of an illness: rheumatoid arthritis, 20 years, Long-term Hormone prednisone.After using 3 courses for the treatment of of Chinese medicine composition of the present invention, hormone is all stopped using, and symptom is eliminated, and rheumatoid factor is turned out cloudy, the slightly biased height of erythrocyte sedimentation rate, and life, action are normal.
application examples 3
Patient, Ye Jiying, 45, female, people from Jiangbei District, Chongqing City.Rheumatoid arthritis has the medical history of about 3 years, and nearest 1 year is relatively serious, lies on a bed, will someone hold up when standing up, after time of lying on a bed a period of time longer than the time of Go to ground activity.Take methotrexate and diclofenac, obviously do not take effect.After using 3 courses for the treatment of of Chinese medicine composition of the present invention, action is basic recovers normal, and pain obviously alleviates, and morning is stiff not obvious.Hormone subtracts 1 by a course for the treatment of, is kept to present half from 4, and within 2 weeks, after date hormone just can have been stopped using.
application examples 4
Patient, Ke Changwen, man, 35 years old, Quanzhou City of Fujian Province people from Jinjiang City.Suffer from rheumatoid arthritis about 5 years, take meloxicam before, significantly do not take effect.After using Chinese medicine composition 7 staggering amount of the present invention, pain starts to alleviate, stiff phenomenon elimination in morning after the course for the treatment of.
application examples 5
Patient, Zhang Cuizhi, female, 54 years old, Yongfeng people from town, Loudi City of Hunan Province Shuangfeng County.Oneself has 3 years to suffer from rheumatoid arthritis.Be originally the pill always eating a people from Guizhou, eat and once can protect two days, do not eat at once inactive while you're at it, foot has not also been walked, and the medicine eating other is useless, but after this pill has been eaten, the face of people is as having got fat, and suspection is hormone, but does not eat and not all right.Since employing Chinese medicine composition of the present invention, after continuous 7 days, this pill can be eaten.But swell and do not disappear, still have the sensation of pain.Taken that the chances are 26 days till now, the swollen place of finger starts detumescence, and pain perception is so unobvious.Some housework can be done, but cold water can not be descended.
Above preferred embodiment, just for instruction and explanation of content of the present invention, does not form the restriction to content of the present invention.Although inventor enumerates in more detail to invention has been, but, the content that those skilled in the art discloses according to summary of the invention part and embodiment, various amendment can be made or/and it is obvious for supplementing or adopting similar mode to substitute to described specific embodiment, and technique effect of the present invention can be realized, therefore, repeat no longer one by one herein.The term occurred in the present invention, for the elaboration of technical solution of the present invention and understanding, is not construed as limiting the invention.
Claims (3)
1. treat rheumatism, a rheumatoid Chinese medicine composition, it is characterized in that being made up of the traditional Chinese medicinal material raw materials of following weight:
Herba Begoniae Yunnanensis 20-50 gram, Caulis Spatholobi 6-12 gram, Radix Rehmanniae 5-8 gram, Herba Epimedii 5-8 gram, Radix Glycyrrhizae 1-5 gram, Stigma Croci 3-7 gram,
Described Chinese medicine composition is prepared as follows:
Caulis Spatholobi, the Radix Rehmanniae, Herba Epimedii, Radix Glycyrrhizae, Stigma Croci, add water by proportioning and boil 1-2 hour, after leaching medicine juice, in medicine juice, add Herba Begoniae Yunnanensis soak more than 30 minutes, pull out after abundant absorption medicine juice, be placed on that temperature is 20-25 DEG C, relative air humidity is under the environment of 50-58%, go mouldy under lucifuge, ventilation condition more than 48 hours, joining concentration is again soak 10-20 minute in the Qiang Bing Ji – β – cyclodextrin aqueous solution of 5%, finally dries the Herba Begoniae Yunnanensis obtaining handling well.
2. a kind of Chinese medicine composition as claimed in claim 1, is characterized in that, described Herba Begoniae Yunnanensis is Tripterygium hypoglaucum.
3. the application of a kind of Chinese medicine composition that one of claim 1-2 is described on preparation treatment rheumatism, medicine for treating rheumatoid arthritis.
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| CN201210184477.0A CN102670871B (en) | 2012-06-06 | 2012-06-06 | Traditional Chinese medicine combination for rheumatism and rheumatoid arthritis and application thereof |
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| CN201210184477.0A CN102670871B (en) | 2012-06-06 | 2012-06-06 | Traditional Chinese medicine combination for rheumatism and rheumatoid arthritis and application thereof |
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| CN106039174A (en) * | 2016-07-07 | 2016-10-26 | 罗淇 | Traditional Chinese medicinal liquor for treating osteoarthrosis |
| CN105963613A (en) * | 2016-07-07 | 2016-09-28 | 罗淇 | Traditional Chinese medicine medicinal liquor for treating osteoarthrosis |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1099983A (en) * | 1993-09-09 | 1995-03-15 | 袁双田 | Medicine for treating rheumatoid or rheumatic arthritis and hyperosteogeny, and method for preparing same |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1099983A (en) * | 1993-09-09 | 1995-03-15 | 袁双田 | Medicine for treating rheumatoid or rheumatic arthritis and hyperosteogeny, and method for preparing same |
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