CN102657918A - Focusing method and device - Google Patents
Focusing method and device Download PDFInfo
- Publication number
- CN102657918A CN102657918A CN2012101428953A CN201210142895A CN102657918A CN 102657918 A CN102657918 A CN 102657918A CN 2012101428953 A CN2012101428953 A CN 2012101428953A CN 201210142895 A CN201210142895 A CN 201210142895A CN 102657918 A CN102657918 A CN 102657918A
- Authority
- CN
- China
- Prior art keywords
- digital signal
- transducer array
- signal
- target area
- array
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title claims abstract description 39
- 230000005284 excitation Effects 0.000 claims abstract description 60
- 238000012545 processing Methods 0.000 claims abstract description 30
- 238000005070 sampling Methods 0.000 claims abstract description 13
- 238000005086 pumping Methods 0.000 claims description 62
- 238000006243 chemical reaction Methods 0.000 claims description 27
- 230000003321 amplification Effects 0.000 claims description 23
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 23
- 238000004364 calculation method Methods 0.000 claims description 11
- 230000003044 adaptive effect Effects 0.000 abstract description 6
- 238000009210 therapy by ultrasound Methods 0.000 abstract 1
- 238000005516 engineering process Methods 0.000 description 19
- 230000008520 organization Effects 0.000 description 9
- 238000010586 diagram Methods 0.000 description 5
- 238000002679 ablation Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 230000006870 function Effects 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- 206010028980 Neoplasm Diseases 0.000 description 3
- 238000002604 ultrasonography Methods 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 238000002059 diagnostic imaging Methods 0.000 description 2
- 238000003384 imaging method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000013334 tissue model Methods 0.000 description 2
- 238000003325 tomography Methods 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000013500 data storage Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 238000012797 qualification Methods 0.000 description 1
- 210000000352 storage cell Anatomy 0.000 description 1
Images
Landscapes
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
- Measurement Of Velocity Or Position Using Acoustic Or Ultrasonic Waves (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Abstract
The invention relates to a focusing method and a focusing device. The method comprises the following steps of: calculating time delay of the original excitation digital signal of a transducer array according to the distance between a target region and the transducer array, processing the original excitation digital signal based on the time delay to generate a first excitation signal of the transducer array, exciting the transducer array by using the first excitation signal to make the transducer array send a first focused sound beam to the target region, receiving a reflected sound wave from the target region by using the transducer array, sampling the reflected sound wave from the target region to generate a first digital signal, performing time reversal on the first digital signal to generate a second digital signal, processing the second digital signal to generate a second excitation signal of the transducer array, and exciting the transducer array by using the second excitation signal to make the transducer array send a second focused sound beam to the target region. By the method and the device, adaptive high-accuracy focusing can be realized in human tissue with the characteristics of non-uniformity and the like, so that the accuracy of ultrasonic treatment is improved.
Description
Technical field
The present invention relates to biomedical engineering field, relate in particular to a kind of focus method and device.
Background technology
At present high intensity focused ultrasound technology (high-intensity focused ultrasound, HIFU) in the main type of focusing have: self-focusing, sound lens focusing and electronically phased array row focus on.Different with preceding two kinds of types of focusing; The treatment head of electronically phased array row supersonic therapeutic system comprises a plurality of little transducer array elements; The purpose that phase place through controlling single array element pumping signal or time delay reach sound beam focusing, this electronically phased array row focusing technology has been represented current state-of-the-art technology.
The sketch map of Fig. 1 for utilizing electronically phased array row focusing technology to focus in the prior art.As shown in the figure, form the position that focused beam focuses on the place, target area through each array element that encourages bowl-shape transducer, thereby the focus in the ablation tissue is the target area.Its concrete implementation procedure is: at first; By ultrasonic diagnosis technology (type-B ultrasonic; B ultrasonic) or electronic computer x-ray tomography technology (electronic computer X-ray tomography technique; CT) etc. the imaging of medical technology is confirmed the position to the target area of human body particular organization, is foreign bodies such as tumor such as the target area.Then according to the time delay of each array element of bowl-shape transducer to each array element excitation signal of distance calculation transducer of target area; Last each array element of bowl-shape transducer is sent acoustic beam and is focused on the target area simultaneously and with particular organization's ablation of target area to the target area.
Said method only decides the time delay of excitation signal to the distance of target area according to each array element of bowl-shape transducer.But; Tissue is a kind of non-uniform dielectric; This medium has also that viscous absorbs and nonlinear characteristic, when each array element of bowl-shape transducer after acoustic beam is sent in the target area, the spread speed when acoustic beam is propagated in the various tissues of human body is not identical but variation has taken place separately; And because the nonlinear characteristic of tissue; Different frequency components has different propagation velocity and absorptance in the acoustic beam in same tissue, thereby makes each acoustic beam generation signals wave distortion and time delay change, and finally causes the last focal zone position that forms of each acoustic beam to be squinted or focal zone area increase etc. and can not obtain the focusing effect of the best.Simultaneously, the burnt territory shape that electronically phased array row ultrasonic system produces is generally spindle, is difficult to and actual target area well matched.
Summary of the invention
The objective of the invention is, a kind of focus method and device are provided.This method and apparatus utilizes time reversal principle in the tissue of characteristics such as having that non-homogeneous, hot viscous absorbs and non-linear, to realize that adaptive high accuracy focuses on, solved in the prior art because of tissue be that a kind of non-homogeneous, hot viscous absorbs and characteristic medium such as non-linear causes focused beam to focus on the not high problem of accuracy of target area.
For realizing above-mentioned purpose, the invention provides a kind of focus method, said method comprises: according to the time delay of the original excitation digital signal of each array element in the said transducer array of distance calculation of each array element in target area and the transducer array; Said original excitation digital signal is handled and is generated first pumping signal of each array element in the said transducer array based on time delay; Utilize in the said transducer array of said first excitation signal energizes each array element and make said transducer array send first focused beam to said target area; Each array element in the said transducer array receives the reflective sound wave of said target area; The reflective sound wave of said target area is sampled and generated first digital signal; Said first digital signal is carried out time reversal and generates second digital signal; Said second digital signal is handled and is generated second pumping signal of each array element in the said transducer array; Utilize in the said transducer array of said second excitation signal energizes each array element and make said transducer array send second focused beam to said target area.
Preferably, said said first digital signal is carried out time reversal and generates also comprising after second digital signal: store said second digital signal.
Preferably, the said processing in said first pumping signal of said raw digital signal being handled and generated each array element in the said transducer array is that said raw digital signal is carried out digital-to-analogue conversion and power amplification; Said processing in said second pumping signal of said second digital signal being handled and generated each array element in the said transducer array is that said second digital signal is carried out digital-to-analogue conversion and power amplification.
Preferably, the voltage magnitude of said first pumping signal is less than the voltage magnitude of said second pumping signal.
The present invention also provides a kind of focusing arrangement, and said device comprises: control module, transmitter module, transducer array, sampling module and processing module.Control module is used for the time delay according to the original excitation digital signal of each array element in the said transducer array of distance calculation of target area and each array element of transducer array; Also be used for first digital signal is carried out time reversal and generates second digital signal; Transmitter module is used for utilizing said first excitation signal energizes each array element of said transducer array and makes said transducer array send first focused beam to said target area; Also be used for utilizing said second excitation signal energizes each array element of said transducer array and make said transducer array send second focused beam to said target area.Transducer array is used for sending said first focused beam and receiving the reflective sound wave of said target area to said target area; Also be used for sending said second focused beam to said target area; Sampling module is used for the reflective sound wave of said target area is sampled and generated said first digital signal; Processing module is used for said original excitation digital signal is handled and generated first pumping signal of said each array element of transducer array; Also be used for said second digital signal is handled and generated second pumping signal of said each array element of transducer array; Wherein, Said control module is controlled said transmitter module and is launched said first pumping signal to said transducer array; Said transducer array receives after said first pumping signal to said target area and sends said first focused beam and receive the said reflective sound wave of said target area; Said reflective sound wave generates said first digital signal and is sent to said control module after said sampling module sampling; Said control module is carried out time reversal and is generated said second digital signal said first digital signal; Said second digital signal generates said second pumping signal after said processing module, launch said second pumping signal through said transmitter module to said transducer array, and said transducer array sends said second focused beam to said target area after receiving said second pumping signal.
Preferably, said processing module also is used for confirming to encourage once more according to said second digital signal excitation time delay of said second pumping signal of each array element of said transducer.
Preferably, said device also comprises: memory module is used to store said second digital signal.
Preferably, processing is specially described in the said processing module: respectively said original excitation digital signal and said second digital signal are carried out digital-to-analogue conversion and power amplification.Preferably, the voltage magnitude of first pumping signal described in the said processing module is less than the voltage magnitude of said second pumping signal.
Therefore; A kind of focus method disclosed by the invention and device; This method and apparatus reflects the reception signal that obtains through the general's focused beam first time to carry out sending focused beam for the second time once more after time reversal from the target area; Can in the tissue of characteristics such as having that non-homogeneous, viscous absorbs and non-linear, realize that adaptive high accuracy focuses on, thereby improve the accuracy that utilizes this method and apparatus to carry out ultrasonic therapeutic.
Description of drawings
The sketch map of Fig. 1 for utilizing electronically phased array row focusing technology to focus in the prior art;
Fig. 2 is the Organization Chart of a kind of focusing system of the embodiment of the invention;
Fig. 3 is the flow chart of a kind of focus method of the embodiment of the invention;
Fig. 4 is the circuit diagram of the control radiating portion of a kind of focus method of the embodiment of the invention;
Fig. 5 is the circuit diagram that the Return Reception Dept. of a kind of focus method of the embodiment of the invention divides;
The tissue model sketch map of Fig. 6 for using in the embodiment of the invention;
The sound pressure amplitude figure that Fig. 7 uses electronically phased array row focusing technology to focus on for the embodiment of the invention;
Fig. 8 is the embodiment of the invention sound pressure amplitude figure that focusing technology focuses on that reverses service time;
Fig. 9 is the sketch map of a kind of focusing arrangement of the embodiment of the invention.
The specific embodiment
Through accompanying drawing and embodiment, technical scheme of the present invention is done further detailed description below.
The embodiment of the invention is applied to time reversal principle in the HIFU system, overcomes the adverse effect that non-homogeneous, the hot viscous of tissue absorbs and nonlinear characteristic is brought the focusing technology that adopts in the existing HIFU system, focuses on to realize adaptive high accuracy.
Time reversal, method was incorporated into the ultrasound detection field by professor FINK of France the earliest, and it can be implemented in the sound beam focusing imaging in the inhomogeneous medium.Time reversal, the ultimate principle of method was: the mirror of being made up of transducer array unit time reversal receives the pulse echo signal from the target place; Convert thereof into to store with time reversal behind the signal of telecommunication and handle; Then with this time reversal signal be added to and remotivate sound wave on the transducer array, at former target place these sound waves of dispersing are become the convergence sound wave.But up to the present, do not see as yet time reversal method tissue this inhomogeneous have again that viscous absorbs and the medium of nonlinear characteristic in application.
Fig. 2 is the Organization Chart of a kind of focusing system of the embodiment of the invention.As shown in the figure, embodiment of the invention system architecture diagram is specifically by bowl-shape transducer array, control circuit, D/A power amplifier (treatment circuit), compositions such as transceiver circuit and sample circuit.Wherein bowl-shape transducer array is made up of the individual independently array element of 32-256, and the individual features of the mid frequency of each array element and emission, reception is consistent.
In addition, all need to each array element one the tunnel independently launch, reception, D/A power amplifier and sample circuit.
Fig. 3 is the flow chart of a kind of focus method of the embodiment of the invention.Bowl-shape transducer with 64 array elements in the present embodiment is an example.Wherein, The mid frequency of each array element is 1MHz; Control processing circuit by Digital Signal Processing (Digital Signal Processing, DSP) and/or field programmable gate array (Field-Programmable Gate Array FPGA) forms with data storage cell.As scheme saidly, the concrete performing step of present embodiment comprises:
Particularly, to the target target area of human body particular organization (foreign body such as tumor, its position can be by B ultrasonic, medical imaging technologies such as CT obtain).In order to guarantee that the acoustic beam that each array element is sent in the bowl-shape transducer array arrives the target area simultaneously, calculate the time delay of the original excitation digital signal of each array element in the transducer array by control circuit according to the distance of each array element in target area and the transducer array.That is to say that transmission in time will be earlier apart from first pumping signal of near array element with first actuating signal ratio and the target area of the array element of target area distance, final result is that the acoustic beam that each array element is sent arrives the target area simultaneously.
Particularly, original excitation digital signal is carried out digital-to-analogue conversion and power amplification generates first pumping signal.Wherein, encourage first pumping signal that each array element of bowl-shape transducer uses for through the signal after the power amplification, voltage magnitude is lower, and approximately 40-70 lies prostrate more, so the energy of first focused beam is less.
After step 304, transducer array were sent first focused beam, first focused beam that arrives the target area was reflected, and each array element of transducer receives the sound wave that the target area reflects.
Particularly, when first focused beam arrives the target target area, owing to exist difference between the parameters,acoustic of target area foreign body tissue and other normal structures of human body, will reflective sound wave, behind reflective sound wave arrival transducer, independently received by each array element in the transducer array.
Particularly, first digital signal that control processing circuit will receive each array element of transducer carries out time reversal, and first digital signal that promptly arrives first is put behind, after to first digital signal be placed on the front.Shown in formula (1).
Wherein,
Be first digital signal, T
0Be a self-defining bigger constant,
Be second digital signal that first digital signal is carried out generate after time reversal.
Particularly, control processing circuit control radiating circuit also makes it launch second pumping signal, and then encourage each array element of bowl-shape transducer to send accurate second focused beam towards the position, target area of destination organization again once more.Wherein, encourage second pumping signal that each array element of bowl-shape transducer uses for through the signal after the power amplification once more, voltage magnitude about more than 100 lies prostrate; Greater than first pumping signal; So the energy of second focused beam is big, focus on the target area after, thereby ablation is positioned at the focus of target area.
Fig. 4 is the circuit diagram of the control radiating portion of a kind of focus method of the embodiment of the invention.As shown in the figure, the control emission function in the embodiment of the invention by control circuit 41, linear voltage regulator 42, memory circuit 43, to generate with communication interface 44, the waveform of host computer be the control transmitter module completion that digital-to-analogue conversion DA circuit 45, power amplification circuit 46 and high voltage power supply 47 are formed.
The operation principle of this control radiating portion is: control circuit 41 is according to the time delay of the original excitation digital signal of each array element in the distance calculation excitation transducer array of each array element in target area and the transducer array, and generating through waveform is that digital-to-analogue conversion DA circuit 45,46 pairs of original excitation digital signals of controlled power amplifying circuit carry out generating first pumping signal after digital-to-analogue conversion and the power amplification.Utilize the lower-wattage amplification to obtain the first lower pumping signal of voltage magnitude, each array element in the excitation transducer array, thus make transducer array send the first less focused beam of energy to the target area direction.
In addition, after control circuit 41 carries out generating second digital signal after time reversal according to the reflected signal that receives.Generating through waveform is that digital-to-analogue conversion DA circuit 45,46 pairs second digital signals of controlled power amplifying circuit carry out generating second pumping signal after digital-to-analogue conversion and the power amplification; Utilization obtains the second bigger driving voltage of voltage magnitude than higher power amplification multiple; Each array element in the excitation transducer array, thus make transducer array send the second bigger focused beam of energy to the target area direction.
Fig. 5 is the circuit diagram that the Return Reception Dept. of a kind of focus method of the embodiment of the invention divides.As shown in the figure, the reception processing capacity in the embodiment of the invention is formed receiving processing module by pre-amplification circuit 51, analog switching circuit 52, analog digital conversion ADC drive circuit 53, analog digital conversion adc circuit 54 and control circuit 55 and is accomplished.
51 pairs of sound waves that reflect through each array elements reception target area of transducer of pre-amplification circuit amplify.It is that digital sample generates first digital signal with this reflective sound wave through analog digital conversion simultaneously that analog switching circuit 52, analog digital conversion ADC drive circuit 53 and analog digital conversion adc circuit 54 are used for the reflective sound wave of which array element of controlled selection receiving transducer.
Control circuit 55 (being control circuit 41) carries out time reversal with the first all digital signals, generates second digital signal.Wherein, control circuit 55 can be realized separately by DSP, or realized separately by FPGA, can also be realized jointly by DSP and FPGA.
The operation principle that this Return Reception Dept. divides is: first focused beam arrives the target area; Owing to exist difference between the parameters,acoustic of target area foreign body tissue and other normal structures of human body; Will reflective sound wave; After each array element independently received the reflective sound wave of target area in the transducer array, 51 pairs of sound waves that reflect through each array elements reception target area of transducer of pre-amplification circuit amplified.Again through the line of numbers sampling of selecting to go forward side by side of analog switching circuit 52, analog digital conversion ADC drive circuit 53 and analog digital conversion adc circuit 54; Thereby generate first digital signal, then utilize time reversal principle that the first all digital signals is carried out time reversal and generates second digital signal by control circuit 55.It is that digital-to-analogue conversion DA circuit 45,46 pairs second digital signals of controlled power amplifying circuit carry out generating second pumping signal after digital-to-analogue conversion and the power amplification that control circuit 55 (being control circuit 41) generates through waveform; Utilization obtains the second bigger driving voltage of voltage magnitude than higher power amplification multiple; Each array element in the excitation transducer array, thus make transducer array send the second bigger focused beam of energy to the target area direction.
The tissue model sketch map of Fig. 6 for using in the embodiment of the invention.In sketch map, be provided with the different density and the velocity of sound, viscous Absorption and nonlinear interaction.Then, use electronically phased array row focusing technology and time-reversal focusing technology respectively, to target emission focused beam, thereby focus on the position that target is the place, target area, thereby the difference that obtains two kinds of focusing technologies realizes effect.
The sound pressure amplitude figure that Fig. 7 uses electronically phased array row focusing technology to focus on for the embodiment of the invention.As shown in the figure, abscissa is that vertical coordinate is a sound pressure amplitude apart from sound source axial distance (impact point is positioned at σ=1).Black dotted lines is the situation of uniform dielectric in theory, and red solid line is that in fact non-homogeneous, hot viscous absorbs, nonlinear situation.As can be seen from Figure 7, under the non-uniform dielectric situation, the electronically phased array row directly focus on has some deviations.
Fig. 8 is the embodiment of the invention sound pressure amplitude figure that focusing technology focuses on that reverses service time.As shown in the figure, abscissa is that vertical coordinate is a sound pressure amplitude apart from sound source axial distance (impact point is positioned at σ=1).Black dotted lines is represented the emission sound field before time reversal, and red solid line is represented the counter-rotating sound field after time reversal.As can be seen from Figure 8, sound field has formed at the impact point place accurately and has focused on.
Fig. 7 and Fig. 8 are compared and can find out, the time-reversal focusing method has focusing effect more accurately than the direct focussing of phased array.
Therefore, a kind of focus method of the embodiment of the invention is according to the time delay of the original excitation digital signal of each array element in the said transducer array of distance calculation of each array element in target area and the transducer array; First pumping signal with low voltage amplitude of each array element in the said transducer array is handled and generated to said original excitation digital signal, utilize in the said transducer array of said first excitation signal energizes each array element and make said transducer array send the first lower focused beam of energy to said target area; Each array element of said transducer receives the reflective sound wave of said target area; The reflective sound wave of said target area is sampled and generated first digital signal; Said first digital signal is carried out time reversal and generates second digital signal; Said second digital signal is handled and is generated second pumping signal of each array element in the said transducer array; According to each array element in the said transducer array of said second excitation signal energizes and make said transducer array send the second higher focused beam of energy to said target area.So this second focused beam can realize that adaptive high accuracy focuses in the tissue of characteristics such as having that non-homogeneous, viscous absorbs and non-linear, thereby has improved the accuracy that utilizes this method to carry out ultrasonic therapeutic.
Fig. 9 is the sketch map of a kind of focusing arrangement of the embodiment of the invention.As shown in the figure, the embodiment of the invention specifically comprises: control module 91, processing module 92, transmitter module 93, transducer array 94, sampling module 95 and memory module 96.
Control module 91 is used for the time delay according to the original excitation digital signal of each array element in the said transducer array of distance calculation of target area and transducer array 94 each array element.Particularly, to the target target area of human body particular organization (foreign body such as tumor, its position can be by B ultrasonic, medical imaging technologies such as CT obtain).In order to guarantee that the acoustic beam that each array element is sent in the bowl-shape transducer array arrives the target area simultaneously, calculate the time delay of the original excitation digital signal of each array element in the transducer array 94 by control module 91 according to the distance of each array element in target area and the transducer array.That is to say that transmission in time will be earlier apart from first pumping signal of near array element with first actuating signal ratio and the target area of the array element of target area distance, final result is that the focused beam that each array element is sent arrives the target area simultaneously.In addition, control module 91 is used for said first digital signal is carried out time reversal and generates second digital signal; Particularly, first digital signal that control module will receive each array element of transducer carries out time reversal, and first digital signal that promptly arrives first is put behind, after to first digital signal be placed on the front.Shown in formula (1).
Also be used for utilizing said transducer array 94 each array element of said second excitation signal energizes and make said transducer array send second focused beam to said target area.Particularly, control module 91 control transmitter modules 93 also make it launch second pumping signal, and then encourage each array element of bowl-shape transducer array 94 to send accurate second focused beam towards the position, target area of destination organization again once more.Wherein, encourage the voltage magnitude of second pumping signal that each array element of bowl-shape transducer array 94 uses bigger once more, about more than 100 lie prostrate, so the energy of second focused beam is big, focus on the target area after, thereby ablation is positioned at the focus of target area.
Sampling module 95 is used for the reflective sound wave of said target area is sampled and generated first digital signal;
Therefore, a kind of focusing arrangement disclosed by the invention is through the time delay of control module according to the original excitation digital signal of each array element in the said transducer array of distance calculation of each array element in target area and the transducer array; Processing module handles and generates first pumping signal of each array element in the said transducer array to said original excitation digital signal; Transmitter module utilizes each array element in the said transducer array of said first excitation signal energizes; Transducer sends first focused beam and receives the reflective sound wave of said target area to said target area; Sampling module is sampled to the reflective sound wave of said target area and is generated first digital signal; Control module is carried out time reversal and is generated second digital signal said first digital signal; Processing module handles and generates second pumping signal of each array element in the said transducer array to said second digital signal; Transmitter module utilizes in the said transducer array of said second excitation signal energizes each array element and makes said transducer array send second focused beam to said target area.So this second focused beam can realize that adaptive high accuracy focuses in the tissue of characteristics such as having that non-homogeneous, viscous absorbs and non-linear, thereby has improved the accuracy that utilizes this device to carry out ultrasonic therapeutic.
The professional should further recognize; The unit and the algorithm steps of each example of describing in conjunction with embodiment disclosed herein; Can realize with electronic hardware, computer software or the combination of the two; For the interchangeability of hardware and software clearly is described, the composition and the step of each example described prevailingly according to function in above-mentioned explanation.These functions still are that software mode is carried out with hardware actually, depend on the application-specific and the design constraint of technical scheme.The professional and technical personnel can use distinct methods to realize described function to each certain applications, but this realization should not thought and exceeds scope of the present invention.
The software module that the method for describing in conjunction with embodiment disclosed herein or the step of algorithm can use hardware, processor to carry out, perhaps the combination of the two is implemented.Software module can place the storage medium of any other form known in random access memory (RAM), internal memory, read only memory (ROM), electrically programmable ROM, electrically erasable ROM, depositor, hard disk, moveable magnetic disc, CD-ROM or the technical field.
The above-described specific embodiment; The object of the invention, technical scheme and beneficial effect have been carried out further explain, and institute it should be understood that the above is merely the specific embodiment of the present invention; And be not used in qualification protection scope of the present invention; All within spirit of the present invention and principle, any modification of being made, be equal to replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (9)
1. a focus method is characterized in that, said method comprises:
Time delay according to the original excitation digital signal of each array element in the said transducer array of distance calculation of each array element in target area and the transducer array;
Said original excitation digital signal is handled and is generated first pumping signal of each array element in the said transducer array based on time delay;
Utilize in the said transducer array of said first excitation signal energizes each array element and make said transducer array send first focused beam to said target area;
Each array element in the said transducer array receives the reflective sound wave of said target area;
The reflective sound wave of said target area is sampled and generated first digital signal;
Said first digital signal is carried out time reversal and generates second digital signal;
Said second digital signal is handled and is generated second pumping signal of each array element in the said transducer array;
Utilize in the said transducer array of said second excitation signal energizes each array element and make said transducer array send second focused beam to said target area.
2. focus method according to claim 1 is characterized in that, said said first digital signal is carried out time reversal and generate also comprising after second digital signal:
Store said second digital signal.
3. focus method according to claim 1; It is characterized in that the said processing in said first pumping signal of said raw digital signal being handled and generated each array element in the said transducer array is that said raw digital signal is carried out digital-to-analogue conversion and power amplification; Said processing in said second pumping signal of said second digital signal being handled and generated each array element in the said transducer array is that said second digital signal is carried out digital-to-analogue conversion and power amplification.
4. focus method according to claim 1 is characterized in that the voltage magnitude of said first pumping signal is less than the voltage magnitude of said second pumping signal.
5. a focusing arrangement is characterized in that, said device comprises: control module, transmitter module, transducer array, sampling module and processing module.
Control module is used for the time delay according to the original excitation digital signal of each array element in the said transducer array of distance calculation of target area and each array element of transducer array; Also be used for first digital signal is carried out time reversal and generates second digital signal;
Transmitter module is used for utilizing said first excitation signal energizes each array element of said transducer array and makes said transducer array send first focused beam to said target area; Also be used for utilizing said second excitation signal energizes each array element of said transducer array and make said transducer array send second focused beam to said target area.
Transducer array is used for sending said first focused beam and receiving the reflective sound wave of said target area to said target area; Also be used for sending said second focused beam to said target area;
Sampling module is used for the reflective sound wave of said target area is sampled and generated said first digital signal;
Processing module is used for said original excitation digital signal is handled and generated first pumping signal of said each array element of transducer array; Also be used for said second digital signal is handled and generated second pumping signal of said each array element of transducer array;
Wherein, Said control module is controlled said transmitter module and is launched said first pumping signal to said transducer array; Said transducer array receives after said first pumping signal to said target area and sends said first focused beam and receive the said reflective sound wave of said target area; Said reflective sound wave generates said first digital signal and is sent to said control module after said sampling module sampling; Said control module is carried out time reversal and is generated said second digital signal said first digital signal; Said second digital signal generates said second pumping signal after said processing module, launch said second pumping signal through said transmitter module to said transducer array, and said transducer array sends said second focused beam to said target area after receiving said second pumping signal.
6. focus method according to claim 5 is characterized in that, said processing module also is used for confirming to encourage once more according to said second digital signal excitation time delay of said second pumping signal of each array element of said transducer.
7. focus method according to claim 5 is characterized in that, said device also comprises:
Memory module is used to store said second digital signal.
8. focus method according to claim 5 is characterized in that, handles being specially described in the said processing module:
Respectively said original excitation digital signal and said second digital signal are carried out digital-to-analogue conversion and power amplification.
9. focus method according to claim 5 is characterized in that the voltage magnitude of first pumping signal is less than the voltage magnitude of said second pumping signal described in the said processing module.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210142895.3A CN102657918B (en) | 2012-05-07 | 2012-05-07 | A kind of focus method and device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210142895.3A CN102657918B (en) | 2012-05-07 | 2012-05-07 | A kind of focus method and device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102657918A true CN102657918A (en) | 2012-09-12 |
| CN102657918B CN102657918B (en) | 2015-09-09 |
Family
ID=46767579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210142895.3A Expired - Fee Related CN102657918B (en) | 2012-05-07 | 2012-05-07 | A kind of focus method and device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102657918B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104353196A (en) * | 2014-11-07 | 2015-02-18 | 天津医科大学 | Amplitude modulation method for high-density transcranial ultrasound focusing |
| CN107050630A (en) * | 2017-04-01 | 2017-08-18 | 深圳先进技术研究院 | A kind of System and method for that particulate is manipulated based on time reversal technology |
| CN110613476A (en) * | 2018-06-19 | 2019-12-27 | 青岛海信医疗设备股份有限公司 | Ultrasonic signal processing method and device |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4951653A (en) * | 1988-03-02 | 1990-08-28 | Laboratory Equipment, Corp. | Ultrasound brain lesioning system |
| CN1978977A (en) * | 2006-12-01 | 2007-06-13 | 北京工业大学 | Supersonic guide-wave time reversion detection apparatus and method for defect of pipeline |
| CN101862511A (en) * | 2010-05-07 | 2010-10-20 | 上海交通大学 | Multi-channel high precision phase control signal generation device |
| CN202637748U (en) * | 2012-05-07 | 2013-01-02 | 中国科学院声学研究所 | Focusing device |
-
2012
- 2012-05-07 CN CN201210142895.3A patent/CN102657918B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4951653A (en) * | 1988-03-02 | 1990-08-28 | Laboratory Equipment, Corp. | Ultrasound brain lesioning system |
| CN1978977A (en) * | 2006-12-01 | 2007-06-13 | 北京工业大学 | Supersonic guide-wave time reversion detection apparatus and method for defect of pipeline |
| CN101862511A (en) * | 2010-05-07 | 2010-10-20 | 上海交通大学 | Multi-channel high precision phase control signal generation device |
| CN202637748U (en) * | 2012-05-07 | 2013-01-02 | 中国科学院声学研究所 | Focusing device |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104353196A (en) * | 2014-11-07 | 2015-02-18 | 天津医科大学 | Amplitude modulation method for high-density transcranial ultrasound focusing |
| CN107050630A (en) * | 2017-04-01 | 2017-08-18 | 深圳先进技术研究院 | A kind of System and method for that particulate is manipulated based on time reversal technology |
| WO2018176526A1 (en) * | 2017-04-01 | 2018-10-04 | 深圳先进技术研究院 | Time reversal technique-based system and method for manipulating particles |
| CN110613476A (en) * | 2018-06-19 | 2019-12-27 | 青岛海信医疗设备股份有限公司 | Ultrasonic signal processing method and device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102657918B (en) | 2015-09-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5355924B2 (en) | Ultrasonic diagnostic equipment | |
| US9247923B2 (en) | Received data processing apparatus of photoacoustic tomography | |
| JP4991355B2 (en) | Ultrasonic diagnostic apparatus and ultrasonic probe | |
| US9575165B2 (en) | Ultrasound probe and ultrasound imaging system | |
| US10123765B2 (en) | Ultrasound probe and ultrasound diagnostic apparatus | |
| KR101456924B1 (en) | Method for Compensating Focal Point, Ultrasound Medical Apparatus Therefor | |
| CN104614728B (en) | A kind of supersonic imaging device and imaging method | |
| JP2005517515A (en) | Portable 3D ultrasound system | |
| JPH0394743A (en) | Method and apparatus for localizing reflective target acoustically | |
| CN202637748U (en) | Focusing device | |
| JP2012235830A (en) | Subject information acquisition device | |
| CN109212037A (en) | A kind of Air Coupling ultrasonic phase array detection device | |
| CN102657918B (en) | A kind of focus method and device | |
| US9763646B2 (en) | Method and systems for adjusting a pulse generated for ultrasound multi-line transmit | |
| KR101398005B1 (en) | HIFU system using by handheld type therapy ultrasonic transducer | |
| CN112790785B (en) | Shear wave elastic imaging method and system | |
| CN115990039A (en) | Ultrasonic imaging method, device, equipment and medium for multi-beam focusing emission | |
| Arnal et al. | Tunable time-reversal cavity for high-pressure ultrasonic pulses generation: A tradeoff between transmission and time compression | |
| JP2012115558A (en) | Ultrasonic diagnostic apparatus | |
| Kim et al. | Multiple transmit focusing using modified orthogonal Golay codes for small scale systems | |
| JP4023909B2 (en) | Ultrasonic imaging device | |
| CN117100317B (en) | Large-aperture ultra-fast ultrasonic imaging system and method | |
| Assef et al. | A programmable FPGA-based 8-channel arbitrary waveform generator for medical ultrasound research activities | |
| Karzova et al. | Nonlinear effects in ultrasound fields of diagnostic-type transducers used for kidney stone propulsion: Characterization in water | |
| CN102793566B (en) | System and method for generating acoustic radiation force |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150909 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |