CN102657564A - Biodegradable vascular scaffold - Google Patents
Biodegradable vascular scaffold Download PDFInfo
- Publication number
- CN102657564A CN102657564A CN2012101444424A CN201210144442A CN102657564A CN 102657564 A CN102657564 A CN 102657564A CN 2012101444424 A CN2012101444424 A CN 2012101444424A CN 201210144442 A CN201210144442 A CN 201210144442A CN 102657564 A CN102657564 A CN 102657564A
- Authority
- CN
- China
- Prior art keywords
- waveform
- intravascular stent
- connecting rod
- vascular scaffold
- biodegradable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Landscapes
- Prostheses (AREA)
Abstract
The invention discloses a biodegradable vascular scaffold, and belongs to the technical field of medical instruments. The vascular scaffold is characterized in that at least six supporting bodies form a tubular netlike structure in the axial direction through connecting rods, each supporting body is formed by connecting at least eight basic supporting units in the circumferential direction, and each basic supporting unit is formed by splicing two upward U waveform rods, two inverse U waveform rods, a C waveform rod and two half C waveform rods; and the connecting rods of the vascular scaffold comprise linear, C-shaped or S-shaped basic connecting rods, and the connecting rods are used for connecting the tops of C waveforms of two adjacent basic supporting units in the axial direction to form the whole vascular scaffold structure. The vascular scaffold has the effects and advantages of high flexibility, uniform deformation, enough radial supporting strength, biocompatibility and degradability; and the mechanical property requirement and the using requirement of the vascular scaffold are well met.
Description
Technical field
The invention belongs to technical field of medical instruments, relate to a kind of biodegradable intravascular stent.
Background technology
Intravascular stent is as keeping the unobstructed core devices of lesion vessels in the percutaneous transluminal coronary angioplasty, from twentieth century the research to it has just been arranged mid-term.At present; The process from bare metal stent to the biodegradable metals support has mainly been experienced in the development of intravascular stent, because metal rack behind implant into body rejection can take place, and will carry out second operation; This has not only increased the difficulty of treatment, and therapeutic effect is not fairly obvious.Though biodegradable metal rack takes out without second operation after implanting arteries, the probability that thrombosis and restenosis take place is very high, and the effect of lesions treatment is unsatisfactory, and lesions also pathological changes can take place once more after the metal rack degraded.And the Biodegradable polymeric support is compared with biodegradable metal rack with bare metal stent; Not only have enough mechanical strengths within a certain period of time; And the respiratory system and the urinary system of the carbon dioxide of final degradation generation and water process human body excrete some side effect that can avoid metal rack to bring.
U.S. FDA has ratified to can be used for biological degradable material that human body is implanted into has polylactic acid (PLA), PLLA (PLLA) and polylactide/gather glycolide copolymer (PLGA) etc.; They not only have good bio-compatible performance and degradation property; Also has good thermal property; And final catabolite is harmless to human non-toxic, is the polymeric material of current medically extensive use.But the yield strength of biological degradable material is less; Can not well satisfy the support performance of intravascular stent; Reasonably the intravascular stent structure can remedy such defective, and good submissive performance and even expansion character can not only be provided, and can also guarantee that intravascular stent has enough support strengths.
Summary of the invention
The technical problem that the present invention will solve provides a kind of biodegradable intravascular stent; Optimal Structure Designing through intravascular stent provides enough support strength, compliance and even dilatancy, and Biodegradable material has good biocompatibility and degradability simultaneously.
Technical scheme of the present invention is:
A kind of biodegradable intravascular stent; Its skeleton constitutes pipe type netted structure by 6 supporters through connecting rod in the axial direction at least; Each supporter is connected and composed by at least 8 basic support units at circumferencial direction; Basic support unit is spliced by two positive U waveform bars, two waveform of falling U bars, C waveform bar and two and half C waveform bars, and connects successively through connecting rod.Connecting rod comprises the connecting rod that is the basis with straight line, C shape or S shape, and the top that connects C waveform in adjacent two basic support units in the axial direction forms whole intravascular stent structure, and can only there be a kind of connecting rod of structure in every kind of intravascular stent structure.The cross section of intravascular stent supporter and connecting rod is identical.
The length of intravascular stent and external diameter can confirm that wall thickness can be chosen as 0.02 ~ 0.5mm according to the clinical practice needs.
Effect of the present invention and benefit are that the support unit of intravascular stent of the present invention not only can provide enough radial support power in the intravascular stent process of expansion; The tight connection of support unit can also guarantee the uniformity of intravascular stent expansion process, thereby reduces because the scratch blood vessel that inhomogeneous expansion brought; The biodegradability polymeric material not only has good bio-compatible performance and degradation property, and carbon dioxide and water that final degradation produces also is the metabolite of human body, and is nontoxic, some side effect that can avoid metal rack to bring.
Description of drawings
Accompanying drawing 1 is the flat deployable structure sketch map of intravascular stent of the present invention.
Accompanying drawing 2 is the basic support unit structural representation of Fig. 1.
Accompanying drawing 3 is the linear connecting rod of Fig. 1.
Accompanying drawing 4 is the C shape connecting rod of Fig. 1.
Accompanying drawing 5 is the S shape connecting rod of Fig. 1.
Among the figure: 1 intravascular stent planar structure; 2 basic support units; 3U waveform bar; 4C waveform bar;
5 linear connecting rods; 6C shape connecting rod; 7S shape connecting rod.
The specific embodiment
Be described in detail specific embodiment of the present invention below in conjunction with technical scheme and accompanying drawing.
In conjunction with shown in Figure 1, embodiments of the invention are made up of with connecting rod basic support unit 2, and its skeleton is spliced into pipe type netted structure by six circle supporters 2 through connecting rod in the axial direction, respectively along the axial and circumferential symmetry.Connecting rod is the linear linkage unit, connects the top of two adjacent basic supporter C waveforms respectively.The cross section of support unit and connecting rod is identical, and the porosity of intravascular stent is 75%.
In conjunction with shown in Figure 2, basic support unit of the present invention is spliced by two positive U waveform bars, two waveform of falling U bars, C waveform bar and two and half C waveform bars.
In conjunction with shown in Figure 3, connecting rod of the present invention is the linear connecting rod, connects the top of C waveform in adjacent two basic support units respectively.
In conjunction with shown in Figure 4, connecting rod of the present invention is a C shape connecting rod, connects the top of C waveform in adjacent two basic support units respectively.
In conjunction with shown in Figure 5, connecting rod of the present invention is a S shape connecting rod, connects the top of C waveform in adjacent two basic support units respectively.
Claims (4)
1. biodegradable intravascular stent; It is characterized in that intravascular stent constitutes pipe type netted structure by 6 supporters through connecting rod in the axial direction at least; Each supporter is connected and composed by at least 8 basic support units at circumferencial direction, and each basic support unit is spliced by two positive U waveform bars, two waveform of falling U bars, C waveform bar and two and half C waveform bars.
2. a kind of biodegradable intravascular stent according to claim 1; It is characterized in that: the connecting rod of said intravascular stent comprises the connecting rod that is the basis with straight line, C shape or S shape, and the top that connects C waveform in adjacent two basic support units in the axial direction forms whole intravascular stent structure.
3. a kind of biodegradable intravascular stent according to claim 1 and 2 is characterized in that: the cross section of said intravascular stent supporter and connecting rod is identical.
4. a kind of biodegradable intravascular stent according to claim 1 and 2 is characterized in that: the length of intravascular stent and external diameter wall thickness are 0.02 ~ 0.5mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210144442.4A CN102657564B (en) | 2012-05-10 | 2012-05-10 | Biodegradable vascular scaffold |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210144442.4A CN102657564B (en) | 2012-05-10 | 2012-05-10 | Biodegradable vascular scaffold |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102657564A true CN102657564A (en) | 2012-09-12 |
| CN102657564B CN102657564B (en) | 2014-11-12 |
Family
ID=46767238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210144442.4A Expired - Fee Related CN102657564B (en) | 2012-05-10 | 2012-05-10 | Biodegradable vascular scaffold |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102657564B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108261275A (en) * | 2016-12-31 | 2018-07-10 | 先健科技(深圳)有限公司 | Bioabsorbable stent |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997032543A1 (en) * | 1996-03-05 | 1997-09-12 | Divysio Solutions Ulc. | Expandable stent and method for delivery of same |
| CN1296398A (en) * | 1998-04-01 | 2001-05-23 | 阔纳姆医药公司 | Expandable unit cell and intraluminal stent |
| CN1533290A (en) * | 2001-02-01 | 2004-09-29 | ��Ԩ��ѧ��ҵ��ʽ���� | Stent |
| CN2768714Y (en) * | 2004-11-22 | 2006-04-05 | 微创医疗器械(上海)有限公司 | Flexible blood vessel stent |
| CN1977778A (en) * | 2005-12-08 | 2007-06-13 | 上海康德莱企业发展集团有限公司 | Vascular stent |
| CN101642397A (en) * | 2009-08-20 | 2010-02-10 | 华南理工大学 | Netty circular tube type intravascular stent |
| US20110144736A1 (en) * | 2002-12-31 | 2011-06-16 | Abbott Cardiovascular Systems Inc. | Flexible stent |
-
2012
- 2012-05-10 CN CN201210144442.4A patent/CN102657564B/en not_active Expired - Fee Related
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997032543A1 (en) * | 1996-03-05 | 1997-09-12 | Divysio Solutions Ulc. | Expandable stent and method for delivery of same |
| CN1296398A (en) * | 1998-04-01 | 2001-05-23 | 阔纳姆医药公司 | Expandable unit cell and intraluminal stent |
| CN1533290A (en) * | 2001-02-01 | 2004-09-29 | ��Ԩ��ѧ��ҵ��ʽ���� | Stent |
| US20110144736A1 (en) * | 2002-12-31 | 2011-06-16 | Abbott Cardiovascular Systems Inc. | Flexible stent |
| CN2768714Y (en) * | 2004-11-22 | 2006-04-05 | 微创医疗器械(上海)有限公司 | Flexible blood vessel stent |
| CN1977778A (en) * | 2005-12-08 | 2007-06-13 | 上海康德莱企业发展集团有限公司 | Vascular stent |
| CN101642397A (en) * | 2009-08-20 | 2010-02-10 | 华南理工大学 | Netty circular tube type intravascular stent |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108261275A (en) * | 2016-12-31 | 2018-07-10 | 先健科技(深圳)有限公司 | Bioabsorbable stent |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102657564B (en) | 2014-11-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR101231197B1 (en) | Polymeric stent | |
| US8603155B2 (en) | Stent having improved stent design | |
| CN204951247U (en) | Biodegradable metal blood vessel support | |
| US20100249905A1 (en) | Balloon expandable bioabsorbable stent with a single stress concentration region interconnecting adjacent struts | |
| CN105992571B (en) | There is high-fatigue strength and the thin support member support and its manufacture method of radial strength as made from biologically absorbable polymer | |
| CN202184823U (en) | Micropore coronary absorbable stent | |
| CN201840555U (en) | Vessel stent being beneficial to being pressed and held | |
| CN106361478B (en) | A kind of mixed type balloon-expandable intravascular stent | |
| CN105726174B (en) | A kind of intravascular stent, preparation method and application | |
| US20180104044A1 (en) | Close-cell structured stent, a preparation method and use thereof | |
| CN104382671A (en) | Degradable human body stent capable of effectively preventing transposition and reducing hyperplasia and manufacturing method | |
| CN106691647B (en) | A kind of biodegradable metals intravascular stent and its application | |
| WO2009137993A1 (en) | Net-like and intravascular stent | |
| CN109640882A (en) | A kind of complete biological absorbable blood vessel polymer support of implanted | |
| CN2920185Y (en) | Micro-porous coronary stent | |
| CN201055442Y (en) | Novel blood vessel support | |
| CN2885176Y (en) | A self-expanding vascular stent | |
| CN102657564B (en) | Biodegradable vascular scaffold | |
| CN204169954U (en) | A kind of degradable human body alimentary canal support that effectively can prevent displacement, reduce hypertrophy | |
| WO2017039389A1 (en) | Medical stent | |
| CN104644295A (en) | Absorbable luminal stent and preparation method thereof | |
| CN111603284A (en) | Absorbable zinc-based alloy drug-loaded stent | |
| CN111374809B (en) | Vertebral artery stent | |
| CN208552143U (en) | A kind of endovascular stent and product | |
| CN201727614U (en) | Novel slippery buckle biological absorbable support |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20141112 Termination date: 20170510 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |