CN102648891A - Composition capable of disintegrating water-containing powder and preparation method thereof - Google Patents
Composition capable of disintegrating water-containing powder and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/08—Oxides; Hydroxides
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0216—Solid or semisolid forms
- A61K8/022—Powders; Compacted Powders
- A61K8/0225—Granulated powders
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- A—HUMAN NECESSITIES
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
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Abstract
The invention relates to a powder-containing-water preparation containing a large quantity of aqua and moisturizing ingredients as well as the functional ingredients at the same time, and a preparation method thereof. The invention specifically relates to a composition capable of disintegrating water-containing powder and a preparation method thereof, wherein the composition has a powder-like appearance, and can be used to release aqueous phase indegrients by using fingers or make-up tools.
Description
Technical field
The present invention relates to contain moisture in a large number and the composition of preserving moisture; Contain powder Bao Shui (water in powder) preparation of functional components and preparation method thereof simultaneously; Particularly; Relating to mode of appearance is powder, but when exerting pressure with finger or cosmetic applicators etc., can discharge collapsible water-containing powder composition of water-phase component and preparation method thereof.
Background technology
The collapsible water-containing powder is characterised in that; Utilization can absorb the water absorbing agent of the water soluble ingredient (hereinafter to be referred as water-phase component) that comprises little water internally; Fixedly water-phase component is arranged water-fast (waterproof, hydrophobic) property fine powder and oil resistant (grease proofing, oleophobic) property fine powder then around it, makes said water absorbing agent keep pulverulence; Do not form pulpous state or paste and can not assemble; When on skin, applying the back disintegrate, provide unique usability and variation of usability, particularly these powder that preserve moisture sense or water moisture feeling can be provided.And these powder can also be with stable moisture powder morphology, to skin water solublity whiten material, antioxidant content and improve wrinkle and become to grade is provided.
In the past be that the dosage form of basis is through with after water absorbing agent (gellant) and hydrophobicity and the oleophobic property powder mixes with the water absorbing agent; Add water-phase component; Process dosage form through simple manual the stirring, the general shape of the powder that is generated is after water absorbing agent absorbs water-phase component, and hydrophobicity and oleophobic property powder wrapped are around it; Globular water proofing property powder all is centered around around the water absorbing agent, its objective is to guarantee the mobile and stable of dosage form.Original expection water absorbing agent is when absorbing water; Hydrophobicity and oleophobic property powder be also with the around of water absorbing agent, can prevent thus that hydrous powdery from assembling and volume becomes big, thereby the stability that prevents dosage form reduces; But in fact this phenomenon can spontaneously not take place; Even take place in the part, whole stability also plays pendulum, and when practical application, can't make the dosage form of above-mentioned form; Also cause water to produce water droplet even make above-mentioned dosage form, cause hydrous powdery to take place to assemble merging and particle becomes dosage form problem of unstable such as big owing to the stability of dosage form is not good.
In addition, when preparation collapsible water-containing powder, need carry out special handlings such as water-proofing treatment, for example, use the outstanding Teflon of water proofing property that coating processing is carried out on the surface of preparation equipment such as employed fluid bed or Henschel blender the surface of preparation equipment; Use in advance that perhaps the silicones film former applies the preparation equipment surface etc.
Summary of the invention
For this reason; When inventor of the present invention is intended to develop a kind of preparation collapsible water-containing powder; Need not the preparation equipment surface is carried out independent water-proofing treatment, cooling processing etc., also can stably prepare the method for said collapsible water-containing powder, find through utilizing electrostatic attraction " compound " technology between the variety classes powder; Before joining water-phase component in the water absorbing agent; With powder water absorbing agent is carried out pretreatment earlier, can improve the stability of dosage form, thereby accomplish the present invention with fire resistance characteristic.
Therefore, the purpose of this invention is to provide a kind of usability and the water moisture feeling that can give the uniqueness of collapsible water-containing powder, can guarantee simultaneously the collapsible water-containing powder composition and preparation method thereof of the stability of dosage form.
In order to achieve the above object, the present invention provides a kind of by containing the water absorbing agent that adheres to through Electrostatic Absorption and the powder of anti-blocking agent; And the collapsible water-containing powder composition of water-phase component composition.
In addition, the present invention also provides a kind of method for preparing of collapsible water-containing powder composition, and this method comprises: the step that forms powder is mixed with water absorbing agent and anti-blocking agent (anti-flocking agent) in (1) under the 500-5000rpm rotating speed; (2) under the 500-1500rpm rotating speed, will carry out blended step at said powder and the anti-blocking agent that step (1) forms; And blended step will be carried out at mixture and the water-phase component that step (2) obtain in (3) under the 50-400rpm rotating speed.
Water-containing powder composition through the present invention preparation contains stable water-phase component, therefore is easy to store and transportation, and when on skin, applying, because the existence of water-phase component has good moisture preserving effect and refrigerant sense.
The specific embodiment
When perhaps kneading the collapsible water-containing powder composition with the have gentle hands light press, just can easily make its disintegrate, the water-phase component that inside is contained passes to skin." compound " technology of passing through the electrostatic attraction between the variety classes powder that never has in the method for preparing utilization technology in the past of said collapsible water-containing powder composition provided by the invention; The attritive powder that will have water proofing property is attached to the surface of water absorbing agent powder, and the water absorbing agent powder wrapped is got up.The limit is stirred on the composite powder limit of method for preparing sprays with fine water-phase component; Make water-phase component in the composite powder surface adsorption; Absorbed by the water absorbing agent in the composite powder again immediately, can not take place therefore that composite powder is assembled and particle becomes big or water-phase component discharges phenomenons such as forming water droplet from composite powder.
Employed composition is divided into water-phase component, water absorbing agent and three kinds of compositions of anti-blocking agent substantially according to its function in the collapsible water-containing powder composition of the present invention.
The main component of employed water-phase component is water, water solublity wetting agent, stores antiseptic etc. among the present invention, can contain in composition, film former, viscosifier, antiinflammatory, skin barrier reparation composition, chelating agen, astringent, defoamer, cortex inhibitor, cutin remover and the artificial tanning agent that is selected from water solublity organic uv absorbers, pH regulator agent, nertralizer, surfactant, whitening composition, aging resistance composition, antioxidant content, prevention comedo one or more in addition.
Gross weight with the collapsible water-containing powder composition is a benchmark, and the content of water-phase component is 30-95 weight %.The content of water-phase component is during less than 30 weight %, can't the advantage in the use that water-phase component brings be provided to skin; The content of 95 weight % is the limit content that can process dosage form, if surpass this content, changes recipe structure in any case and all can not process stable dosage form.
The water absorbing agent that uses among the present invention is selected from carboxymethyl starch sodium; The methyl hydroxypropyl starch; Carboxymethyl starch; Sad basic succinic acid aluminum starch; Sad basic succinic acid starch calcium; Methylcellulose; Ethyl cellulose; Hydroxy ethyl cellulose; Hydroxyethyl ethylcellulose; Hydroxypropyl emthylcellulose; Nitrocellulose; Cellulose sodium sulfate; Sodium carboxymethyl cellulose; Microcrystalline Cellulose; Cellulose powder; Different dodecenyl succinic succinic acid starch calcium; In denaturation cornstarch and the hydroxyethyl-cellulose one or more.Gross weight with the collapsible water-containing powder composition is a benchmark, and the content of water absorbing agent is 1-20 weight %.If the content of water absorbing agent can't reach the amount that makes dosage form stable less than 1 weight %, so dosage form is unstable and have dry sensation when using; If the content of water absorbing agent greater than 20 weight %, also has dry sensation when being coated to skin, and owing to the formation film causes rubbing with the hands the mud phenomenon.
The anti-blocking agent that uses among the present invention is the stability that is used to improve water absorbing agent, and particularly, anti-blocking agent directly is adsorbed onto through electrostatic attraction and forms composite powder on the water absorbing agent, and between composite powder, further improves the stability of composite powder.Anti-blocking agent is divided into inorganic matter and Organic substance, can be selected from the Muscovitum of titanium dioxide, zinc oxide, ferrum oxide, Barium Sulfate, Talcum, Muscovitum, silicon dioxide, synthetic fluorophologopite, titanium dioxide coated and in the boron nitride one or more as the inorganic matter of anti-blocking agent; Can be selected from polyester as the Organic substance of anti-blocking agent; Polyethylene; Polypropylene; Polystyrene; Methylmethacrylate copolymer
methyl methacrylate cross linked polymer; 12-nylon; 6-nylon; Nylon 66; Polystyrene; The styrene-propene acid copolymer; Vinyl chloride-base polymer; Vinyl acetate; Tetrafluoro ethylene polymer; Polyorganosilsesquioande resin
polydimethylsiloxanecopolymer copolymer
is gathered one or more in methyl silsesquioxane
and the polysilsesquioxane
.Gross weight with the collapsible water-containing powder composition is a benchmark, and the content of anti-blocking agent is 0.5-20 weight %.The content of anti-blocking agent can't satisfy the stability of dosage form during less than 0.5 weight %; When the content of anti-blocking agent is 20 weight %, can give full play to its anti performance, during therefore greater than this content, not only bad for economy, but also the usability of reduction cosmetics.
In order to improve water proofing property, anti-blocking agent, especially, the inorganic matter anti-blocking agent uses surface treated, and preferred the use carried out surface-treated with coating material.Weight with anti-blocking agent is benchmark, and the consumption of said coating material is 1-20 weight %.The consumption of said coating material is during less than 1 weight %, can not fully carry out surface-coated and can't show water proofing property; When the consumption of said coating material is 20 weight %, just can fully carry out surface treatment, this amount of surpassing is excessive use, therefore causes the increase of expense.
The coating material is selected from this time using fluorinated alcohol phosphate
perfluorinated octyltriethoxysilane
polymethylsiloxane
polydimethylsiloxane
stearic acid
octyl triethoxy silane
Stearyl Valley acid disodium
isostearyl isostearate
and metal soaps
in one or more.In order to improve the stability of dosage form, the preferred use fluoridized coating material or silicones class coating material.
When anti-blocking agent has the particle size similar or bigger with water absorbing agent; Form through adding up at random also can be brought stability; But the particle size of the anti-blocking agent on the water absorbing agent that directly adheres to through Electrostatic Absorption is preferably smaller or equal to 1/3 of water absorbing agent; Be more preferably less than at 1/10 o'clock that equals water absorbing agent, adhere to more densely on the water absorbing agent surface and help forming composite powder, and help the stability of dosage form.In addition, the anti-blocking agent that between composite powder, improves stability is preferably dimensioned to be 1/3 particle more than or equal to water absorbing agent.
Collapsible water-containing powder composition of the present invention prepares through following method:
(1), forms the step of composite powder with water absorbing agent and anti-blocking agent high-speed stirred.
With mixing under water absorbing agent and the anti-blocking agent high speed rotating, through Electrostatic Absorption, the water absorbing agent surface is arranged and be fixed on to anti-blocking agent equably, thereby form composite powder.At this moment, the size of employed anti-blocking agent is littler than water absorbing agent, is preferably smaller or equal to 1/3 of water absorbing agent; Be more preferably less than and equal 1/10 of water absorbing agent.
In this step, compare water absorbing agent and have undersized anti-blocking agent and produce electrostatic attraction or disperse accumulative anti-blocking agent is powerful, thereby under high-speed stirred, mix in order to make.
Rotary speed when mixing water absorbing agent and anti-blocking agent is preferably 500-5000rpm.Rotary speed is during less than 500rpm, and anti-blocking agent and water absorbing agent can't carry out compound, and anti-blocking agent can't fully disperse; Rotary speed has surpassed the speed that reaches required purpose, and has brought over loading and produce heat to instrument during greater than 5000rpm, may cause the fault that can't expect.
In addition, in this step, contact with water absorbing agent in order to make anti-blocking agent, thereby anti-blocking agent is attached on the water absorbing agent equably, need to mix the sufficiently long time as the variety classes powder.Preferred incorporation time is 2-10 minute.Incorporation time can not form composite powder during less than 2 minutes fully; When incorporation time surpasses 10 minutes, consumes the unnecessary energy and generation heat, thereby cause the fault that to expect.
(2) with the composite powder that forms in the above-mentioned steps and anti-blocking agent blended step under relative stirring at low speed.
In this step, 1/3 the anti-blocking agent of size more than or equal to water absorbing agent mixed with formed composite powder, between composite powder, fill anti-blocking agent, thereby improve the stability of composite powder.
The formation step that is different from composite powder in this step, is mixed anti-blocking agent and also can be given full play to its effect under stirring at low speed, therefore need not under high-speed stirred, to mix, and preferably under the rotating speed of 500-1500rpm, mixes.
(3) under stirring at low speed, the mixture and the water-phase component of above-mentioned steps (2) carried out blended step.
Under stirring at low speed, slowly add water-phase component in the mixture that in step (2), obtains, perhaps use devices such as air gun or spray gun to spray, thereby water-phase component is contacted with water absorbing agent equably.
In this step, preferred blended rotary speed is 50-400rp.Rotary speed is during less than 50rpm, can't be with the powder uniform mixing, thus cause water-phase component to be adsorbed equably; Rotating speed is during greater than 400rpm, because excessive velocities, makes by the water-phase component of water absorbing agent absorption to be hit and to cause being released again, thereby causes dosage form unstable.
Method of the present invention can make the collapsible water-containing powder composition be easy to be prepared into dosage form, and the dosage form of the collapsible water-containing powder composition through the preparation of this method has good stable property, can stably contain water-phase component, therefore is easy to store and transportation.
In addition, the present invention also provides a kind of cosmetic composition that contains said collapsible water-containing powder composition.Gross weight with cosmetic composition is a benchmark, and the content of said collapsible water-containing powder composition is 10-90 weight %, but is not limited to this.Said cosmetic composition can be prepared into the various dosage forms of not extrusion forming, and for example, powdery eye shadow, rouge, dual-purpose muffin are at interior vanishing cream or have the forms such as sun-proof powder of anti-ultraviolet effect.
Through embodiment and Test Example content of the present invention is elaborated below.But just in order to help to understand content of the present invention, the scope of claim of the present invention does not limit thus for these embodiment and Test Example.
The preparation of embodiment 1-2 and Comparative Examples 1-4
The compositions that has prepared embodiment 1-2 and Comparative Examples 1-4 according to the component of following table 1.Each components contents unit is weight %, and the surface treatment % of each raw material is that the weight according to each raw material is the ratio that benchmark obtains.
Table 1
The method for preparing of embodiment 1-2
(1) mentioned component 1-3 is put into the Henschel blender, under the 1000rpm rotating speed, mixed 5 minutes.
(2) in the mixture that step (1) obtains, adding mentioned component 4-5, is 500rpm with the rotational speed regulation of Henschel blender, mixes 2 minutes.
(3) composition 8 is joined in the composition 7, at room temperature stirring and dissolving is mixed with composition 6 then.
(4) utilize air gun that the mixture of above-mentioned steps (3) is sprayed to the mixture that step (2) obtains, at this moment, the rotational speed regulation of Henschel blender is below the 400rpm, to mix.
(5) after finishing, the mixture spraying that above-mentioned steps (3) is obtained stops the Henschel blender.
The method for preparing of Comparative Examples 1-2
(1) mentioned component 1-3 is put into the Henschel blender, under the 60rpm rotating speed, mixed 5 minutes.
(2) in the mixture that step (1) obtains, adding mentioned component 4-5, is 60rpm with the rotational speed regulation of Henschel blender, mixes 2 minutes.
(3) composition 8 is joined in the composition 7, at room temperature stirring and dissolving is mixed with composition 6 then.
(4) utilize air gun that the mixture of above-mentioned steps (3) is sprayed to the mixture that step (2) obtains, at this moment, the rotational speed regulation of Henschel blender is below the 400rpm, to mix.
(5) after finishing, the mixture spraying that above-mentioned steps (3) is obtained stops blender.
The method for preparing of Comparative Examples 3
(1) mentioned component 1-2 is put into the Henschel blender, under the 1000rpm rotating speed, mixed 5 minutes.
(2) in the mixture that step (1) obtains, adding mentioned component 4-5, is 500rpm with the rotational speed regulation of Henschel blender, mixes 2 minutes.
(3) composition 8 is joined in the composition 7, at room temperature stirring and dissolving is mixed with composition 6 then.
(4) utilize air gun that the mixture of above-mentioned steps (3) is sprayed to the mixture that step (2) obtains, at this moment, the rotational speed regulation of Henschel blender is below the 400rpm, to mix.
(5) after finishing, the mixture spraying that above-mentioned steps (3) is obtained stops blender.
The method for preparing of Comparative Examples 4
(1) mentioned component 3-5 is put into the Henschel blender, under the 500rpm rotating speed, mixed 2 minutes.
(2) composition 8 is joined in the composition 7, at room temperature stirring and dissolving is mixed with composition 6 then.
(3) utilize air gun that the mixture of above-mentioned steps (2) is sprayed to the mixture that step (1) obtains, at this moment, the rotational speed regulation of Henschel blender is below the 400rpm, to mix.
(4) after finishing, the mixture spraying that above-mentioned steps (3) is obtained stops to stir.
Test Example 1: sensory test (organic functions test)
Embodiment 1-2 and the compositions of Comparative Examples 1-4 of preparation according to the method described above are applied to 10 women in 25-38 year under the same conditions, and the easy disintegrating property when dry sensation to the sense of preserving moisture, after applying and use is estimated.
Particularly, use the compositions scrape said embodiment 1-2 of bale-out 0.1g and Comparative Examples 1-4, on the back of the hand with the 1cm diameter coated evenly after, smear with pointing 3 circles of picture.Applied back 30 seconds, and estimated the water moisture feeling and the sense of preserving moisture; Applied back 1 minute, and estimated dry sensation.In addition, produce the degree of water droplet when detecting by an unaided eye 3 circles of finger picture spread compositions, after comparing and estimating, estimate the easy disintegrating property when using.
Each project is divided into benchmark evaluation with 7, and the effect of mark high praise project more is good more.In addition, in order to reduce error, with 10 minutes be the interval, average after implementing 3 times by the same way.The result is as shown in table 2.
Table 2.
| Embodiment 1 | Embodiment 2 | Comparative Examples 1 | Comparative Examples 2 | Comparative Examples 3 | Comparative Examples 4 | |
| Water moisture feeling, the sense of preserving moisture | 6 | 5.2 | Can't estimate | Can't estimate | 2.8 | Can't estimate |
| Apply the after drying sense | 3 | 3.8 | Can't estimate | Can't estimate | 6.5 | Can't estimate |
| Easy disintegrating property during use | 6.6 | 6.3 | Can't estimate | Can't estimate | 3.4 | Can't estimate |
Shown in above-mentioned table 2, Comparative Examples 1-2 and Comparative Examples 4 are prepared into pulpous state rather than powder dosage form, therefore can't estimate.Though Comparative Examples 3 is prepared into the powder dosage form, the power of preserving moisture is not good, causes serious dry sensation after the use.On the contrary, not only dry sensation was lighter after embodiments of the invention 1-2 applied, and the power of preserving moisture is good, and the disintegrate of powder is also easy during use.
Test Example 2: the estimation of stability of dosage form
In order to confirm the stability of dosage form, stability, storage stability, impact stability and ageing stability when having estimated preparation.
Stability during preparation through when preparation particle state or remain in the amount of the moisture on the chamber wall, the generation of water droplet etc. and estimate.
Storage stability is estimated with aggregation extent, the water droplet generation degree of each dosage form through after storing 7 days at 45 ℃ of temperature chambers.
Impact stability through utilizing shaking table, after 80rpm rotation 6 hours, estimate with the aggregation extent of each dosage form, the generation degree of water droplet.
Ageing stability is estimated with the aggregation extent of dosage form, the generation degree of water droplet through after storing 1 month at room temperature state.
Evaluation result is as shown in table 3 below, and metewand is following:
◎ is very outstanding
Zero is outstanding
△ is general
* poor
Table 3.
As above shown in the table 3, Comparative Examples 1-2 and Comparative Examples 4 are prepared into pulpous state rather than powder dosage form, therefore can't estimate, but can see that embodiment 1-2 and Comparative Examples 3 have good dosage form stability.From then on can know that the stability of the dosage form of collapsible water-containing powder composition compares its constituent, more depend on its preparation method.
Claims (23)
1. collapsible water-containing powder composition is characterized in that said composition comprises: contain the water absorbing agent that adheres to through electrostatic attraction and the powder of anti-blocking agent; And water-phase component.
2. powder composition according to claim 1, wherein, said anti-blocking agent is between said powder inside and powder.
3. powder composition according to claim 2 wherein, is included in the inner anti-blocking agent of said powder and is of a size of smaller or equal to 1/3 of said water absorbing agent particle size; Anti-blocking agent between said powder is of a size of more than or equal to 1/3 of said water absorbing agent particle size.
4. powder composition according to claim 1, wherein, said water-phase component is absorbed by said water absorbing agent.
5. powder composition according to claim 1; Wherein, said water absorbing agent is selected from one or more in carboxymethyl starch sodium, methyl hydroxypropyl starch, carboxymethyl starch, sad basic succinic acid aluminum starch, sad basic succinic acid starch calcium, methylcellulose, ethyl cellulose, hydroxy ethyl cellulose, hydroxyethyl ethylcellulose, hydroxypropyl emthylcellulose, nitrocellulose, cellulose sodium sulfate, sodium carboxymethyl cellulose, microcrystalline Cellulose, cellulose powder, different dodecenyl succinic succinic acid starch calcium, denaturation cornstarch and the hydroxyethyl-cellulose.
6. powder composition according to claim 1 wherein, is a benchmark with the gross weight of collapsible water-containing powder composition, and the content of said water absorbing agent is 1-20 weight %.
7. powder composition according to claim 1; Wherein, said anti-blocking agent be selected from titanium dioxide, zinc oxide, ferrum oxide, Barium Sulfate, Talcum, Muscovitum, silicon dioxide, synthetic fluorophologopite, titanium dioxide coated Muscovitum, boron nitride, polyester, polyethylene, polypropylene, polystyrene, methylmethacrylate copolymer, methyl methacrylate cross linked polymer, 12-nylon, 6-nylon, nylon 66, polystyrene, styrene-propene acid copolymer, vinyl chloride-base polymer, polyvinyl acetate, tetrafluoro ethylene polymer, Polyorganosilsesquioande resin, polydimethylsiloxanecopolymer copolymer, gather in methyl silsesquioxane and the polysilsesquioxane one or more.
8. powder composition according to claim 1 wherein, is a benchmark with the gross weight of collapsible water-containing powder composition, and the content of said anti-blocking agent is 0.5-20 weight %.
9. powder composition according to claim 1 wherein, is a benchmark with the gross weight of collapsible water-containing powder composition, and the content of said water-phase component is 30-95 weight %.
10. powder composition according to claim 1, wherein, said anti-blocking agent uses coating material that coating processing has been carried out on the surface.
11. powder composition according to claim 10; Wherein, said coating material is selected from one or more in fluorinated alcohols phosphate ester, perfluoro capryl triethoxysilane, polymethyl siloxane, polydimethylsiloxane, stearic acid, triethoxy octyl group silane, stearoyl-glutamic acid disodium, isooctadecanol isostearate and the metallic soap.
12. powder composition according to claim 10 wherein, is a benchmark with the weight of said anti-blocking agent, the consumption of said coating material is 1-20 weight %.
13. the method for preparing of a collapsible water-containing powder composition is characterized in that, this method comprises: the step that forms powder is mixed with water absorbing agent and anti-blocking agent in (1) under the 500-5000rpm rotating speed; (2) under the 500-1500rpm rotating speed, will carry out blended step at said powder and the anti-blocking agent that step (1) forms; (3) under the 50-400rpm rotating speed, will carry out blended step at mixture and the water-phase component that step (2) obtain.
14. method for preparing according to claim 13, wherein, the anti-blocking agent that is used for step (1) is of a size of smaller or equal to 1/3 of said water absorbing agent particle size; The anti-blocking agent that is used for step (2) is of a size of more than or equal to 1/3 of said water absorbing agent particle size.
15. method for preparing according to claim 13; Wherein, Said water absorbing agent is selected from carboxymethyl starch sodium, methyl hydroxypropyl starch, carboxymethyl starch, sad basic succinic acid aluminum starch, one or more in sad basic succinic acid starch calcium, methylcellulose, ethyl cellulose, hydroxy ethyl cellulose, hydroxyethyl ethylcellulose, hydroxypropyl emthylcellulose, nitrocellulose, cellulose sodium sulfate, sodium carboxymethyl cellulose, microcrystalline Cellulose, cellulose powder, different dodecenyl succinic succinic acid starch calcium, denaturation cornstarch and the hydroxyethyl-cellulose.
16. method for preparing according to claim 13 wherein, is a benchmark with the gross weight of collapsible water-containing powder composition, the content of said water absorbing agent is 1-20 weight %.
17. method for preparing according to claim 13; Wherein, said anti-blocking agent be selected from titanium dioxide, zinc oxide, ferrum oxide, Barium Sulfate, Talcum, Muscovitum, silicon dioxide, synthetic fluorophologopite, titanium dioxide coated Muscovitum, boron nitride, polyester, polyethylene, polypropylene, polystyrene, methylmethacrylate copolymer, methyl methacrylate cross linked polymer, 12-nylon, 6-nylon, nylon 66, polystyrene, styrene-propene acid copolymer, vinyl chloride-base polymer, polyvinyl acetate, politef, Polyorganosilsesquioande resin, polydimethylsiloxanecopolymer copolymer, gather in methyl silsesquioxane and the polysilsesquioxane one or more.
18. method for preparing according to claim 13 wherein, is a benchmark with the gross weight of collapsible water-containing powder composition, the content of said anti-blocking agent is 0.5-20 weight %.
19. method for preparing according to claim 13 wherein, is a benchmark with the gross weight of collapsible water-containing powder composition, the content of said water-phase component is 30-95 weight %.
20. method for preparing according to claim 13, wherein, said anti-blocking agent uses coating material that coating processing has been carried out on the surface.
21. method for preparing according to claim 20; Wherein, said coating material is selected from one or more in fluorinated alcohols phosphate ester, perfluoro capryl triethoxysilane, polymethyl siloxane, polydimethylsiloxane, stearic acid, triethoxy octyl group silane, stearoyl-glutamic acid disodium, isooctadecanol isostearate and the metallic soap.
22. method for preparing according to claim 20 wherein, is a benchmark with the weight of said anti-blocking agent, the consumption of said coating material is 1-20 weight %.
23. cosmetic composition that contains any described powder composition among the claim 1-12.
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| Application Number | Priority Date | Filing Date | Title |
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| KR1020110016426A KR101825494B1 (en) | 2011-02-24 | 2011-02-24 | Powder composition containing collapsible water and the method for preparing the same |
| KR10-2011-0016426 | 2011-02-24 |
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| CN102648891A true CN102648891A (en) | 2012-08-29 |
| CN102648891B CN102648891B (en) | 2016-06-08 |
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| CN109431865A (en) * | 2018-11-01 | 2019-03-08 | 汕头市亚联药业有限公司 | A kind of quick-fried water being directed to the crowd of staying up late is white and its prepares |
| CN110801408A (en) * | 2019-12-09 | 2020-02-18 | 共聚生化科技（昆山）有限公司 | Metal light-sensitive waterproof eye shadow powder and preparation method thereof |
| CN111195209A (en) * | 2020-01-21 | 2020-05-26 | 杭州百芮生物科技有限公司 | Novel thixotropic powder-coated high-proportion water-phase composition and preparation method thereof |
| CN113230192A (en) * | 2021-05-31 | 2021-08-10 | 欧诗漫生物股份有限公司 | Powder-coated water essence and preparation method and use method thereof |
| CN113924081A (en) * | 2019-06-06 | 2022-01-11 | 株式会社诺薇雅 | Cosmetic preparation |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| KR101997440B1 (en) * | 2017-10-27 | 2019-07-08 | 코스맥스 주식회사 | Powder cosmetic composition comprising starch |
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| US20020192169A1 (en) * | 2001-02-22 | 2002-12-19 | L'oreal | Matte-rendering cosmetic composition containing a polytetrafluoroethylene aqueous dispersion and use thereof |
| WO2003022234A1 (en) * | 2001-09-12 | 2003-03-20 | Unilever Plc | Cosmetic composition with organic sunscreen and porous powder particles |
| US20060008485A1 (en) * | 2004-07-12 | 2006-01-12 | Ferone James J | Packaged cosmetic compositions and related methods |
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| US20020192169A1 (en) * | 2001-02-22 | 2002-12-19 | L'oreal | Matte-rendering cosmetic composition containing a polytetrafluoroethylene aqueous dispersion and use thereof |
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| CN109431865A (en) * | 2018-11-01 | 2019-03-08 | 汕头市亚联药业有限公司 | A kind of quick-fried water being directed to the crowd of staying up late is white and its prepares |
| CN113924081A (en) * | 2019-06-06 | 2022-01-11 | 株式会社诺薇雅 | Cosmetic preparation |
| CN113924081B (en) * | 2019-06-06 | 2023-08-18 | 株式会社诺薇雅 | Cosmetic product |
| CN110801408A (en) * | 2019-12-09 | 2020-02-18 | 共聚生化科技（昆山）有限公司 | Metal light-sensitive waterproof eye shadow powder and preparation method thereof |
| CN111195209A (en) * | 2020-01-21 | 2020-05-26 | 杭州百芮生物科技有限公司 | Novel thixotropic powder-coated high-proportion water-phase composition and preparation method thereof |
| CN113230192A (en) * | 2021-05-31 | 2021-08-10 | 欧诗漫生物股份有限公司 | Powder-coated water essence and preparation method and use method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20120097086A (en) | 2012-09-03 |
| KR101825494B1 (en) | 2018-02-07 |
| CN102648891B (en) | 2016-06-08 |
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