Background technology
Vacuum freeze drier is commonly called as freeze dryer; Be a kind of medicine that is widely used in, the drying equipment of food service industry, its purposes is to let material freeze at low temperatures; Moisture content is wherein distilled under vacuum state, and the moisture content of collecting condensation with the method for condensation is to reach the purpose of material drying and dehydrating.At present, along with China's medicine, food service industry are further adapted to international practices, freeze dryer is also increasingly high in the instructions for use of aspects such as vaccine, blood product, bio-pharmaceuticals, medicine, health products.
Generally there is a crucial container that holds medicine the freeze dryer front portion, is called freeze drying box, has piled a piece flaggy can controlling its temperature in freeze drying box inside.Those medicines or biology, chemicals then are positioned on these crucial flaggies.The pharmaceutical technology personnel are exactly the temperature of these flaggies of control, and the goods that come indirect refrigeration or heating to be positioned over make the stage of the freezing → low-temperature distillation → finished product of goods experience realize the process of freeze-drying pharmacy.This inner flaggy of freeze dryer that is positioned in practical application, generally on a flaggy, tends to place at least hundreds of, several thousand bottles freeze-dried products at most, so must have several very important technical characterictics.
Uniformity of temperature profile
Because the freeze-dried products quantity that is positioned over sometimes on the flaggy is many; And just do not accomplish the hundreds of and thousands of goods on the every flaggy are carried out complete monitoring temperature with present science and technology at all; The most feasible way is selected several points exactly and is carried out the local temperature monitoring; And the freeze-dried products state that is defaulted as other is much the same with it, be that representative data is accomplished whole freeze-dry process process with the data of this several Control point, so the temperature uniformity of freeze dryer flaggy is extremely important.If the temperature difference of same flaggy or different flaggies is very big, then the freeze-dry process personnel just could not guarantee the homogeneity of freeze-dried products quality by the gross, bring very big trouble and loss for pharmaceutical manufacturing manufacturer!
The flaggy flatness
Because be positioned over again on the freeze dryer flaggy after being placed in cillin bottle or the goods dish during general freeze-dried products, decisive role is arranged when even so whether the flatness of flaggy is heated for goods or is freezed.The flaggy poor flatness; The goods tray bottom just can only be positioned on the flaggy with the mode that line contacts or point contacts with the cillin bottle bottom; Heat conduction efficiency is had a greatly reduced quality, and causing on the monoblock flaggy need not regional product property heterogeneity, also can produce certain regional goods when serious and scrap in a large number.
Zero leakage
Because for guaranteeing the homogeneity of flaggy bulk temperature, so when making flaggy, often it is made hollow type, the fluid passage of its hollow is circuitous to outlet from import as the labyrinth, in its fluid passage, generally is full of a kind of liquid that is silicone oil.Silicone oil is a kind of very special oils, and its chemistry, physical property are stable, does not fire not quick-friedly, and density is slightly less than water.Under-60 ℃ temperature, can also exist, and this kind liquid quantity of heat storage is huge portability great amount of heat own or cold with liquid form.Freeze dryer at first freezes or heats silicone oil, and it carries a large amount of heats or cold gets into flaggy then, if each parameter control suitably, can the temperature difference of flaggy be controlled at ± 0.5 ℃ within.But silicone oil itself also has a characteristic: its permeability is extremely strong.General silicone oil can be used in during cosmetics make in a large number, as a kind of carrier nutriment is infiltrated people's skin, so this just means that this liquid very easily leaks.As long as the welding of flaggy makes mistakes slightly, silicone oil will be from wherein oozing out, and influence also destroys the goods in the freeze drying box.
Early stage layer structure adopts the base plate punching, and the form of back plug welding is made the fluid passage of silicone oil in the centre of flaggy, and this form of temperature of controlling flaggy through the temperature of control silicone oil is very old.The inner parting bead that adopts rectangle of flaggy; The normal argon arc welding of parting bead and upper plate just can make flaggy be shaped but lower plate must be employed in the method for punching plug welding on the base plate, and done following shortcoming like this: flaggy back welding capacity is very big; The welding heating is surprising; The backboard distortion is so tragic that one cannot bear to look at it, and flaggy is made the later stage need do a large amount of polishing work to the flaggy back, and grinding Lou during polishing sometimes, solder joint causes flaggy to leak.The distortion that flaggy backboard solder joint produces makes has very big gap between parting bead and the backboard, when silicone oil flows in flaggy can from below scurry another side.Cause very inhomogeneous of flaggy temperature.There is a large amount of solder joints at the flaggy back, very bad of the flatness of flaggy.
Summary of the invention
The objective of the invention is to overcome above-mentioned defective; Layer structure is improved, thereby avoid above drawback occurring, make weld seam all in inside; Whole plate atresia and slit do not exist the heat exchange flaggy structure and the manufacturing approach of a kind of freeze dryer of the possibility that flaggy leaks.Its technology is achieved in that the structure that comprises flaggy upper and lower bottom plate, parting bead, copper platinum, it is characterized in that: be provided with the one hermetically-sealed construction that the soldering of copper platinum becomes between upper and lower bottom plate and the parting bead of placing at interval, be filled with silicone oil between upper and lower bottom plate and parting bead.Its manufacturing approach is: insert copper platinum between the parting bead of upper and lower bottom plate and placement at interval, use the anchor clamps clamping, put into vacuum brazing furnace.High temperature melting copper platinum in stove, in the brazing process, vavuum pump is taken out all air; Comprise upper and lower bottom plate and copper platinum, copper platinum and at a distance between air; Vacuum brazing furnace heats up, reach brazing temperature after, copper platinum is melted, after cooling; The hermetically-sealed construction that is just linked into an integrated entity securely by copper platinum between upper and lower bottom plate and the parting bead is filled the heat exchange flaggy structure of forming a kind of freeze dryer behind the silicone oil.Implementing this technological advantage is: no local welding heating, and the flaggy distortion is little, and good planeness is beneficial to polishing, shaping.The splicing of parting bead and upper and lower bottom plate closely, welding is good, silicone oil can not walk short circuit directly from parting bead top or the bottom scurry the flaggy another side.Can make the flaggy temperature very even.All welding are all inner at flaggy, and are little to the flaggy external action, guarantee the flaggy flatness.Because of all weld seams all in inside, so whole plate atresia and slit, the possibility that does not exist flaggy to leak.
The specific embodiment
Below in conjunction with accompanying drawing the present invention is further described:
See accompanying drawing 1, be provided with copper platinum 3 soldering all-in-one-piece hermetically-sealed constructions between the parting bead 2 of upper and lower bottom plate 1 and placement at interval, 2 of upper and lower bottom plate 1 and parting beads are filled with silicone oil 4.
See accompanying drawing 1, insert copper platinum 3 between the parting bead 2 of upper and lower bottom plate 1 and placement at interval, copper platinum 3 is put according to the direction of accompanying drawing and finished, and is good with the anchor clamps clamping, puts into vacuum brazing furnace.High temperature meeting melting copper platinum 3 in stove, in the brazing process, vavuum pump is taken out all air; Comprise the air between upper and lower bottom plate 1 and copper platinum 3, copper platinum 3 and the parting bead 2; Vacuum brazing furnace heats up, reach brazing temperature after, copper platinum 3 is melted, after cooling; The hermetically-sealed construction that is just linked into an integrated entity securely by copper platinum 3 between upper and lower bottom plate 1 and the parting bead 2 is filled the heat exchange flaggy structure that a kind of freeze dryer is formed in silicone oil 4 backs.