CN102631462A - Traditional Chinese medicine for treating cancer pain - Google Patents

Abstract

A traditional Chinese medicine for treating cancer pain belongs to the field of traditional Chinese medicines for treating cancer and aims to have fine effects and take effect fast. The traditional Chinese medicine is prepared by raw materials including vietnamese sophora roots, ardisia crenata, Chinese angelica, ganoderma lucidum, notoginseng, radix rehmanniae and the like. The traditional Chinese medicine has effects of reinforcing the vital energy and consolidating the constitution, replenishing qi and blood, nourishing yin for moistening dryness, promoting blood circulation, removing blood stasis and stopping pain, and has the advantages of having the remarkable effects and exact efficacy and taking effects fast.

Description

A kind of Chinese medicine of treating cancerous pain

Technical field

The invention belongs to the field of Chinese medicines of treatment tumor.

Background technology

Cancerous pain (abbreviation cancer pain) is one of modal symptom of Advanced Carcinoma Patient, because it is violent and lasting, becomes serious problems that influence the patients with advanced cancer life quality.According to statistics, the whole world has 4,000,000 cancer patients to suffer the torment of pain every year, and there are 1,800,000 cancer pain patients in China every year approximately, is a huge illness colony.From seeing clinically,, be that the doctor trained in Western medicine or the traditional Chinese medical science are all felt very much thorny to the processing of the cancer pain of caused by malignant tumors.The medicine of doctor trained in Western medicine mainly contains non-opium and opiates; Secular clinical practice proves, though the Western medicine of these treatment cancer pains truly has the effect in a period of time, is easy to occur addiction property, drug resistance and dependency; And addiction, drug resistance, dependence three vicious cycle bring great misery to the patient.From the Chinese medicine aspects, there are two significantly deficiencies in the Chinese medicine that cancer pain is treated in present being intended to: the one, and effect is obvious inadequately, and the 2nd, it is slower to take effect.Because can not get the treatment of active drug, large quantities of Advanced Carcinoma Patient enjoy decocting of cancer pain, feel painful especially, in addition overwhelmed with sorrow, patient and family members thereof are very dissatisfied to this.

To problem set forth above, the present invention provides a kind of Chinese medicine of treating cancerous pain, and it is obvious inadequately that it can solve in this type of treatment by Chinese herbs in the past effect; The slower problem that takes effect, effective, instant effect, it is remarkable to have effect; Drug effect is definite, the advantage of quick result.

Summary of the invention

The present invention realizes through following technical scheme:

1, a kind of Chinese medicine of treating cancerous pain adopts the raw material of Chinese medicine preparation, and the weight proportion of raw material of Chinese medicine is:

Radix Sophorae Tonkinensis 3---18 parts of 9 parts of Radix Ardisiae Crenataes 3---9 parts of Radix Angelicae Sinensis 6---

Ganoderma 6---18 parts of 18 portions of Radix Notoginseng 4---12 portions of Radix Rehmanniae 6---

The Chinese medicine of this treatment cancerous pain is processed by following method:

(1) by above-mentioned weight ratio, Ganoderma is extracted ganoderan with decoction and alcohol sedimentation technique, technological process is following: Ganoderma is broken into graininess, crosses 40 mesh sieves →Hot water (95 ℃) lixiviate with 1:20 →Lixiviating solution decompression, concentrated →95% ethanol with 3 times of volumes mixes, left standstill 10-12 hours, centrifugal →Add 75% ethanol, the deposition polysaccharide →Dry the ganoderan extract fine powder;

(2) by above-mentioned weight ratio, Radix Notoginseng is extracted with the alcoholysis water extraction method, method is; With Notoginseng Root with 1.6 times of 70% alcohol desorption after; With 20 times of water level volumes 45 ℃ and-P boiling extraction in reducing pressure under the 0.084MPa, extract 4min/ time 2 times; Extracting solution directly adopts macroporous resin to carry out adsorbing separation and gets extract Radix Notoginseng total arasaponins fine powder after concentrating;

(3) by above-mentioned weight ratio, Radix Sophorae Tonkinensis, Radix Ardisiae Crenatae, Radix Angelicae Sinensis, Radix Rehmanniae are extracted through conventional water extraction process, process extractum, oven dry is pulverized, and gets the extract fine powder; Mix with above-mentioned (1), (2) two kinds of extract fine powders, stir, process Chinese medicine granules, capsule, tablet.

The present invention is according to the folk tradition prescription, and the theory according to traditional Chinese medical science the body resistance strengthening and constitution consolidating, blood circulation promoting and blood stasis dispelling develops meticulously.We research think, the cause of disease of cancer pain, mainly be " because of void then the pain ".Because cancer pain occurs in cancer of late stage, immunity is seriously low, deficiency of qi and blood after the prolonged illness, hyperlipidemia; The resistance of the blood vessel stasis of blood, blood flow is not smooth, causes and organizes blood supply insufficiency, and meridians lose supports; Internal organs loss and cause not Rong Ze pain, positive so-called " arteries and veins tears and blood deficiency, blood deficiency is pain then ".So, control and work as the body resistance strengthening and constitution consolidating, benefiting QI and nourishing blood, promoting blood circulation, removing blood stasis and relieving pain.Ganoderma, Radix Rehmanniae the body resistance strengthening and constitution consolidating among the we, benefiting QI and nourishing blood, tranquilizing by nourishing the heart, tonification the five internal organs, enhancing human body immunity power; 5 all have the blood circulation promoting and blood stasis dispelling function with Radix Angelicae Sinensis, Radix Notoginseng, Radix Ardisiae Crenatae, and " pain relieving " effect is all arranged, and Radix Angelicae Sinensis can passage, nourishing blood, again can blood circulation promoting and blood stasis dispelling, and be to invigorate blood circulation and pain relieving; Radix Notoginseng can blood circulation promoting and blood stasis dispelling, can stop blooding again, hemostasis is arranged and does not stay the characteristics of the stasis of blood, is blood stasis dispelling and pain relieving; The Radix Ardisiae Crenatae expelling wind and removing dampness, promoting blood circulation and stopping pain, removing toxic substances and promoting subsidence of swelling is to subside a swelling and pain relieving, three flavor mutual reinforcements between are more remarkable with the promoting blood circulation and stopping pain effect; The Radix Rehmanniae nourishing YIN and clearing away heat, blood enriching and dryness moistening, cooling blood for hemostasis, for alleviate cancer pain promote the production of body fluid moisturize separate tired; Assistant is with the Radix Sophorae Tonkinensis heat-clearing and toxic substances removing, and it is anticancer to subside a swelling; The traditional Chinese medical science is thought, qi as the commander of blood, and blood being the mother of qi, and Ganoderma, Radix Rehmanniae and Radix Angelicae Sinensis, Radix Notoginseng, Radix Ardisiae Crenatae are associated with, the prosperous hemapodium of gas, QI and blood is full, and " removing " effect of immunity makes blood clean, and no longer thickness is rich mobile, and the resistance of the blood vessel stasis of blood is alleviated, and blood flow is unobstructed; " general rule is not bitterly ", oxygen is full supports plentifully, and the pain natural remission disappears.Make a general survey of full side, all medicine compatibilities complement each other, and bring out the best in each other, and play the body resistance strengthening and constitution consolidating altogether, and benefiting QI and nourishing blood is nourshing Yin and drynsessmoistening prescription, and the merit of promoting blood circulation, removing blood stasis and relieving pain is effective, instant effect, and it is remarkable to have effect, and drug effect is definite, the advantage of quick result.

The specific embodiment

Through following embodiment the present invention is done and to specify:

1, get following prescription (weight is unit by gram):

Radix Sophorae Tonkinensis 300 gram Radix Ardisiae Crenataes 300 gram Radix Angelicae Sinensis 600 grams

Ganoderma 600 gram Radix Notoginseng 400 gram Radix Rehmanniae 600 grams

Press predetermined weight, Ganoderma is extracted with decoction and alcohol sedimentation technique; With the alcoholysis water extraction method Radix Notoginseng is extracted; With conventional water extraction process Radix Sophorae Tonkinensis, Radix Ardisiae Crenatae, Radix Angelicae Sinensis, Radix Rehmanniae are extracted, process extract fine powder 280 grams altogether, said extracted thing fine powder is mixed; Stir, process fine particle, the capsule of packing into No. 0; Process 933 of Chinese medicinal capsules, every capsules includes Chinese medicine extract 0.3 gram.

2, get following prescription (weight is unit by gram):

Radix Sophorae Tonkinensis 600 gram Radix Ardisiae Crenataes 600 gram Radix Angelicae Sinensis 1200 grams

Ganoderma 1200 gram Radix Notoginseng 800 gram Radix Rehmanniae 1200 grams

By above-mentioned same method, process 1866 of Chinese medicinal capsules, every capsules includes Chinese medicine extract 0.3 gram.

3, get following prescription (weight is unit by gram):

Radix Sophorae Tonkinensis 900 gram Radix Ardisiae Crenataes 900 gram Radix Angelicae Sinensis 1800 grams

Ganoderma 1800 gram Radix Notoginseng 1200 gram Radix Rehmanniae 1800 grams

By above-mentioned same method, process 2800 of Chinese medicinal capsules, every capsules includes Chinese medicine extract 0.3 gram.

4, get following prescription (by weight):

9 parts of 4 parts of Radix Angelicae Sinensis of 4 parts of Radix Ardisiae Crenataes of Radix Sophorae Tonkinensis

9 parts of 5 portions of Radix Rehmanniae of 9 portions of Radix Notoginseng of Ganoderma

By above-mentioned same method, process Chinese medicinal capsule, every capsules includes Chinese medicine extract 0.3 gram.

5, get following prescription (by weight):

17 parts of 8 parts of Radix Angelicae Sinensis of 8 parts of Radix Ardisiae Crenataes of Radix Sophorae Tonkinensis

17 parts of 11 portions of Radix Rehmanniae of 17 portions of Radix Notoginseng of Ganoderma

By above-mentioned same method, process Chinese medicinal capsule, every capsules includes Chinese medicine extract 0.3 gram.

Clinical data:

The present invention is an example with traditional Chinese medical science cancer patient, through 19 routine clinical observations.Selecting the tcm diagnosis cancerous pain is standard: cancerous pain appears in the cancer patient, mild pain, and perhaps pain repeatedly, perhaps constant pain perhaps has an intense pain.As above symptom can be made a definite diagnosis.In making a definite diagnosis the object of observation, male's 11 examples, women's 8 examples do not have other serious disease, and the age is 45 years old-69 years old, 58.4 years old mean age.

Efficacy determination:

Press WHO in 1987 about cancer pain degree of adoption integration, i.e. pain classification:

1 minute: pain was light, did not influence sleep and diet.

2.5 divide: the puzzlement pain, pain is outbreak repeatedly, the pain expression occurs, interruption of work during pain, and influence diet, sleep.

5 minutes: pain tired out, constant pain, expression is painful.

7.5 divide: pain---pain is obvious, but still can stand unbearably, and obvious painful expression is arranged.

10 minutes: violent pain---pain acutely unbearably, the significant change of companion's emotion, position, as moan ceaselessly or shout, pulse or accelerated breathing, pale complexion is in a cold sweat, blood pressure drops.

Total points: pain branch+pain hour/day, calculate by above-mentioned score value.

1, produce effects: total points descends more than 50%.

2, effective: total points descends 1% ~ 49%.

3, invalid: pain does not subtract, the disease no change.

During clinical experiment, withdraw other medicines and health nutrient.Taking the Chinese medicinal capsule that the specific embodiment of the invention 2 is made, observed 30 days, is a course of treatment.Instructions of taking: every day 2 times, each 4 capsules, every capsules include Chinese medicine extract 0.3 gram, warm water delivery service after meal, one week the back symptom alleviation is promptly arranged, take 30 days after, symptom is obviously improved.19 philtrums of clinical experiment, produce effects 7 people, effective 9 people, invalid 3 people, total effective rate 84.2%.

Claims (1)

1. Chinese medicine of treating cancerous pain is characterized in that: said Chinese medicine is to adopt the raw material of Chinese medicine preparation, and the weight proportion of raw material of Chinese medicine is:

Radix Sophorae Tonkinensis 3---18 parts of 9 parts of Radix Ardisiae Crenataes 3---9 parts of Radix Angelicae Sinensis 6---

Ganoderma 6---18 parts of 18 portions of Radix Notoginseng 4---12 portions of Radix Rehmanniae 6---

The Chinese medicine of this treatment cancerous pain is processed by following method:

(1) by above-mentioned weight ratio, Ganoderma is extracted ganoderan with decoction and alcohol sedimentation technique, technological process is following: Ganoderma is broken into graininess, crosses 40 mesh sieves →Hot water (95 ℃) lixiviate with 1:20 →Lixiviating solution decompression, concentrated →95% ethanol with 3 times of volumes mixes, left standstill 10-12 hours, centrifugal →Add 75% ethanol, the deposition polysaccharide →Dry the ganoderan extract fine powder;

(2) by above-mentioned weight ratio, Radix Notoginseng is extracted with the alcoholysis water extraction method, method is; With Notoginseng Root with 1.6 times of 70% alcohol desorption after; With 20 times of water level volumes 45 ℃ and-P boiling extraction in reducing pressure under the 0.084MPa, extract 4min/ time 2 times; Extracting solution directly adopts macroporous resin to carry out adsorbing separation and gets extract Radix Notoginseng total arasaponins fine powder after concentrating;

(3) by above-mentioned weight ratio, Radix Sophorae Tonkinensis, Radix Ardisiae Crenatae, Radix Angelicae Sinensis, Radix Rehmanniae are extracted through conventional water extraction process, process extractum, oven dry is pulverized, and gets the extract fine powder; Mix with above-mentioned (1), (2) two kinds of extract fine powders, stir, process Chinese medicine granules, capsule, tablet.