CN102626500A - Medicine for treating acne - Google Patents

Abstract

The invention relates to a medicine for treating acne, particularly to a traditional Chinese medicine which is prepared by adopting traditional Chinese medicines as active pharmaceutical ingredients and used for treating chronic inflammation of hair-follicle sebaceous glands. The medicine, which is composed of realgar, myrrh, musk, fritillaria, radix scrophulariae, cortex dictamni, honeysuckle, salvia miltiorrhiza, radix stemonae, rhubarb, radix angelicae and liquorice, is prepared by the following steps of: oven-drying the active pharmaceutical ingredients, crushing into fine powder and sifting the powder with a 150-mesh sieve, then adding melted yellow vaseline and a dissolved preservative, stirring the obtained mixture well while hot until the medicinal material powder is completely coated by oil film so as to make it form a drug-containing oil phase, pouring boiled purified water into the drug-containing oil phase all at once while the water is hot, and stirring constantly until the drug-containing oil phase cools into cream. The medicine has the functions of inflammation diminishing and swelling reducing, blood activating and menstruation promoting, heat clearing away and stagnation eliminating, and swelling eliminating and pus discharging. For the treatment of acne, the medicine can not only take effect fast, make inflammation disappear quickly, but also can dredge facial collaterals and address both the symptoms and root causes. The medicine provided by the invention has the advantages of high cure rate, no recurrence, no sequela, and that patients feel no pain during treatment.

Description

A kind of medicine of treating acne

Technical field

The present invention relates to a kind of medicine of treating acne, particularly relating to a kind of is the Chinese medicine of the pilosebaceous chronic inflammatory disease of treatment of crude drug preparation with Chinese medicine.

Background technology

Acne is commonly called as " comedo ", is " pimples " " acne " " whelk " " skin sore " etc. again, is because hair follicle and sebaceous gland are blocked a kind of chronic inflammatory disease dermatoses that inflammation caused.It also is one of modal sick kind of beauty treatment skin section.Usually good sending out in face, cervical region, chest and back, shoulder and upper arm.Clinical serves as main performance with hoary hair's acne, blackhead, inflammatory pimple, pustule, tuberosity, cyst etc.This disease adolescence sees more, but also not exclusively receives the restriction of age level, and from child to adult, the people of nearly all age bracket can fall ill.Acne is to occur in pilosebaceous chronic dermatosis, and the factor of generation is varied, but the most directly factor is exactly that pore stops up.After pore stopped up, the oils and fats row of hair follicle the inside did not come out, cumulatively just form one by one little small pox, and comedo comes to this and takes place.Not too serious comedo can both be seen the top of white or black usually; Here it is hoary hair's acne and blackhead, you also can extrude some white secretions, and Here it is is deposited in the oils and fats of pore the inside; Be not dirty thing, neither so-called acarid.As long as pore does not stop up, small pox just can not come up easily.Acne is one of modal sick kind of beauty treatment skin section, is whelk, pimples or acne, folliculitis again, except that children, has 80%～90% people to suffer from this disease or once suffered from this disease (comprising light disease) among the crowd approximately.Traditional Chinese medical science checking, medicinal Flos Rosae Rugosae commonly used is soaked to be drunk or beats powder and spread on face and can effectively treat diseases such as acne.

Summary of the invention

The purpose of this invention is to provide a kind of medicine of treating acne, this medicine antiinflammatory detumescent, promoting blood circulation to restore menstrual flow, the heat clearing away eliminating stagnation, detumescence and apocenosis treatment acne cure rate is high, and relapse rate is low.

Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:

Realgar 25---30 Myrrha 25---30

Moschus 1---3 Bulbus Fritillariae Uninbracteatae 25---30

Radix Scrophulariae 25---30 Cortex Dictamni 25---30

Flos Lonicerae 25---30 Radix Salviae Miltiorrhizae 25---30

The Radix Stemonae 40---50 Radix Et Rhizoma Rhei 50---60

The Radix Angelicae Dahuricae 40---50 Radix Glycyrrhizae 25---30.

Can the above-mentioned raw materials medicine be processed the ointment on the pharmaceutics.

The concrete method for preparing of above-mentioned each component being processed medicine of the present invention is:

With above-mentioned raw materials medicine oven dry, after being ground into fine powder and crossing 150 mesh sieves, add the Yellow Vaselin and the lysed antiseptic that have melted, stir while hot (all being as the criterion by the oil film parcel with medicinal powder) make into the pastille oil phase.The purified water that to boil is disposable while hot to be poured in the pastille oil phase, and ceaselessly stirs until being cooled to cream and get final product.

In the prescription of the present invention, Realgar relieves internal heat anticancer, and it is relieving convulsion to eliminate the phlegm, and parasite killing is treated skin ulcer, antiinflammatory detumescent; The Myrrha blood blood stasis removing that looses, subduing swelling and relieving pain; The Moschus refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, pain relieving; The merit of Bulbus Fritillariae Uninbracteatae relieving cough and resolving phlegm, heat clearing away eliminating stagnation; The Radix Scrophulariae clearing away heat and cooling blood, replenishing YIN and removing heat, eliminating fire and detoxication; The Cortex Dictamni heat clearing and damp drying, dispelling wind for relieving itching, detoxifcation; The Flos Lonicerae heat-clearing and toxic substances removing, the epidemic febrile disease heating; The Radix Salviae Miltiorrhizae promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; The cough-relieving of Radix Stemonae nourishing the lung to keep the adverse QI downward, parasite killing; Radix Et Rhizoma Rhei is attacked stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, detoxifcation; Radix Angelicae Dahuricae expelling wind and cold, understand things pain-stopping, detumescence and apocenosis, dampness leukorrhagia stopping; The Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.More than all medicines share antiinflammatory detumescent, promoting blood circulation to restore menstrual flow, heat clearing away eliminating stagnation, detumescence and apocenosis; To the treatment acne, not only instant effect disappears inflammation fast, and can dredge facial venation, has the effect of treating both the principal and secondary aspects of a disease; Cured substance rate of the present invention is high, does not recur no sequel, patient's no pain during the treatment.

For further investigating the clinical efficacy and the safety of medicine of the present invention, select 300 routine patients with acne that the curative effect of medicine of the present invention is carried out clinical observation.

300 routine cases are divided into two groups at random, and 150 examples are organized in treatment, matched group 150 examples.All cases all meet the diagnostic criteria of acne in " the clinical research guideline of new Chinese medicine treatment acne ".

Diagnostic criteria:

The pubarche morbidity is sent out in face well, is gone up breast and the flourishing position of back sebaceous gland, symmetrical distribution.

Skin lesion is hair follicle property pimple, pustule, tuberosity, cyst, blackhead and cicatrix, with seborrhea, is chronic process.

Therapeutic Method:

Treatment group: use medicine of the present invention, 1-2 time on the one, after earlier affected part being dried with warm water cleaning, evenly be coated with and put one deck on the skin, the preceding use of sleeping.

Matched group: external Viaminate dimension E emulsifiable paste 1-2 time on the one, after earlier affected part being dried with warm water cleaning, evenly is coated with and puts one deck on the skin, the preceding use of sleeping.

The acne curative effect determinate standard:

Clinical recovery: skin lesion all disappears, and only leaves pigmentation and scar scar person.

Produce effects: skin lesion disappears more than 70%, or the order of severity lowers more than 2 degree.

Effectively: skin lesion disappears 30～70%, or more than order of severity attenuating 1 degree, still has the new skin lesion person of appearance.

Invalid: skin lesion disappears below 30%, or the person of increasing the weight of.

Two groups of case treatment back curative effect comparative results are seen table 1.

Table 1 liang group case treatment back curative effect relatively

Group

The example number

Clinical recovery n (%)

Produce effects n (%)

Effective n (%)

Invalid n (%)

Total effective rate n (%)

Matched group

150

125（83.3）

8（5.3）

6（4）

11（7.4）

139（92.7）

The treatment group

150

140（93.3）

5（3.3）

4（2.7）

1（0.7）

149（99.3）

Clinical experiment is the result prove, drug effect of the present invention obviously is superior to matched group, do not see any untoward reaction.

The specific embodiment

Embodiment 1

Get Realgar 30g, Myrrha 30g, Moschus 3g, Bulbus Fritillariae Uninbracteatae 30g; Radix Scrophulariae 30g, Cortex Dictamni 30g, Flos Lonicerae 30g, Radix Salviae Miltiorrhizae 30g; Radix Stemonae 50g, Radix Et Rhizoma Rhei 60g, Radix Angelicae Dahuricae 50g, Radix Glycyrrhizae 30g; With above-mentioned raw materials medicine oven dry, after being ground into fine powder and crossing 150 mesh sieves, add the Yellow Vaselin and the lysed antiseptic that have melted, stir (all being as the criterion by the oil film parcel with medicinal powder) while hot; Make into the pastille oil phase, the purified water that will boil is disposable while hot to be poured in the pastille oil phase, and ceaselessly stirs until being cooled to cream and get final product.

Embodiment 2

Get Realgar 28g, Myrrha 27g, Moschus 2g, Bulbus Fritillariae Uninbracteatae 27g, Radix Scrophulariae 25g; Cortex Dictamni 26g, Flos Lonicerae 28g, Radix Salviae Miltiorrhizae 29g, Radix Stemonae 45g; Radix Et Rhizoma Rhei 58g, Radix Angelicae Dahuricae 48g, Radix Glycyrrhizae 26g is dried the above-mentioned raw materials medicine; After being ground into fine powder and crossing 150 mesh sieves, add the Yellow Vaselin and the lysed antiseptic that have melted, stir while hot (all being as the criterion by the oil film parcel with medicinal powder) make into the pastille oil phase.The purified water that to boil is disposable while hot to be poured in the pastille oil phase, and ceaselessly stirs until being cooled to cream and get final product.

Claims (1)

1. medicine of treating acne is that crude drug prepares by the Chinese medicine of following portions by weight:

Realgar 25---30 Myrrha 25---30

Moschus 1---3 Bulbus Fritillariae Uninbracteatae 25---30

Radix Scrophulariae 25---30 Cortex Dictamni 25---30

Flos Lonicerae 25---30 Radix Salviae Miltiorrhizae 25---30

The Radix Stemonae 40---50 Radix Et Rhizoma Rhei 50---60

The Radix Angelicae Dahuricae 40---50 Radix Glycyrrhizae 25---30.