CN103735821A - Composite medical ointment for treating acne - Google Patents

Composite medical ointment for treating acne Download PDF

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Publication number
CN103735821A
CN103735821A CN201410042597.6A CN201410042597A CN103735821A CN 103735821 A CN103735821 A CN 103735821A CN 201410042597 A CN201410042597 A CN 201410042597A CN 103735821 A CN103735821 A CN 103735821A
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China
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ointment
radix angelicae
medicine
salicylic acid
acne
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CN201410042597.6A
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Chinese (zh)
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CN103735821B (en
Inventor
宋英明
朱妍
李艳红
孙吉凤
刘泱泱
岳红
汪春红
陈娟
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Abstract

The invention provides a composite medical ointment for treating acne. The composite ointment is prepared according to the steps of grinding angelica dahurica, angelica, common myrrh, white alum, atractlylis lancea formalyrata, herba epimedii, lonicera japonica, fructus forsythia, bulbus fritillariae cirrhosae, pangolin scales, rhizoma ligustici wallichii and peppermint into 100-120-mesh powders, adding phenol, salicylic acid and cream base inside and mixing uniformly. The composite medical ointment adopts pure traditional Chinese herbs as the raw material, is scientifically formulated, has strong ability of diminishing inflammation and relieving pain, and has no toxic and side effect, no skin sensibility occurs, and the disease does not recur after cure; and the treatment period of the medicine is short, and the medicine has wide application range and reliable curative effect.

Description

A kind of compound recipe ointment for the treatment of comedo acne
technical field:
The invention provides one and treat comedo acne compound recipe ointment, relate to the medicine of acne, acne infection and cicatrix disease disease, belong to Chinese medicine and pharmacy technical field.
background technology:
Acne is multiple at Young Patients as a kind of commonly encountered diseases, occurs in face, also can occur in thoracic dorsal top and shoulder, also betides once in a while the red pimple at other positions.The vigorous position of sebaceous gland is heavy, the position light (all skin of socket of the eye never involves) that smegma is few.Patient is oily skin mostly, starts to be mostly homeliness type, can occur tuberosity, pustule, abscess, sinus tract or cicatrix later.The course of disease is long, and easily repeatedly, many no conscious symptons, when as obvious in inflammation, can cause pain and touch pain.
On market, external medicine is oxygen benzoyl or tetracycline ointment, erythromycin ointment or lincomycin ointment, the antibiotic such as Azelex, some hormonal medicaments of also interpolation that have; its therapeutic effect has certain limitation; subject range is less, can not remove this sick pathogenesis, is also difficult to control this palindromia; cure the symptoms, not the disease; outbreak repeatedly, is difficult to cure, after long-time use; medicine produces human body also can untoward reaction, and the malpractice that damages appearance face has generation frequently.
summary of the invention:
One disclosed by the invention is treated comedo acne compound recipe ointment, and Chinese and western drugs combination is containing hormone, not evident in efficacy, treating both the principal and secondary aspects of a disease.
The present invention is according to the medically pathogenesis to acne and Therapeutic Principle, the selected pure Chinese herbal medicine with functions such as heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, clearing away heat and cooling blood, anti-inflammatory anti-itchs, in conjunction with modern Western medicine drug, through the science process of preparing Chinese medicine and rigorous operation, make compound medicinal formulation, for eliminating the sick mechanism of acne, make body recovery normal.
Basic prescription of the present invention is by the following medicine Chinese medicine preparation that component is made by ratio of weight and the number of copies:
The Radix Angelicae Dahuricae 20 ~ 30, Radix Angelicae Sinensis 20 ~ 30, Myrrha 20 ~ 30, Alumen 10 ~ 15, the Rhizoma Atractylodis Macrocephalae 10 ~ 15, Herba Epimedii 10 ~ 15, Poria 10 ~ 15, Flos Lonicerae 10 ~ 15, Fructus Forsythiae 10 ~ 15, Bulbus Fritillariae Cirrhosae 10 ~ 15, Squama Manis 5 ~ 10, Rhizoma Chuanxiong 5 ~ 10, Herba Menthae 3 ~ 5, phenol 1 ~ 4, salicylic acid 30 ~ 70, emulsifiable paste matrix 500 ~ 1000.
Preferred prescription of the present invention is:
The Radix Angelicae Dahuricae 25, Radix Angelicae Sinensis 25, Myrrha 25, Alumen 15, the Rhizoma Atractylodis Macrocephalae 15, Herba Epimedii 15, Poria 15, Flos Lonicerae 15, Fructus Forsythiae 15, Bulbus Fritillariae Cirrhosae 10, Squama Manis 8, Rhizoma Chuanxiong 8, Herba Menthae 5, phenol 2, salicylic acid 60, emulsifiable paste matrix 1000.
Concrete processing procedure of the present invention is as follows:
According to ointment processing technology traditional on pharmaceutics, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Myrrha, Alumen, the Rhizoma Atractylodis Macrocephalae, Herba Epimedii, Poria, Flos Lonicerae, Fructus Forsythiae, Bulbus Fritillariae Cirrhosae, Squama Manis, Rhizoma Chuanxiong, Herba Menthae etc. are pulverized to 100 ~ 120 orders, add phenol, salicylic acid, emulsifiable paste matrix to stir and make compound ointment; Concrete technology should meet 2000 editions unguentum project relevant requirements of Pharmacopoeia of People's Republic of China.
In the present invention, the Radix Angelicae Dahuricae has disease dehumidifying, evacuation of pus granulation promoting, promoting blood circulation and stopping pain; Radix Angelicae Sinensis has rheumatic arthralgia, injury from falling down, ulcer sores; Myrrha fall apart blood blood stasis removing, subduing swelling and relieving pain, ulcer sore pain; Flos Lonicerae, Fructus Forsythiae have heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain effect; Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI, dampness diuretic; Herba Epimedii has kidney-replenishing, bone and muscle strengthening, the effect of wind-damp dispelling; Poria promoting diuresis to eliminate damp pathogen, and the property of medicine is gentle, diuretic and do not hinder healthy energy, is promoting diuresis to eliminate damp pathogen key medicine; Bulbus Fritillariae Cirrhosae dissipating depression of QI eliminating stagnation; Herba Menthae reducing heat and dispersing lung-QI; Squama Manis has promoting blood circulation to remove obstruction in the collateral, detumescence and apocenosis, wind-expelling pain-stopping; Rhizoma Chuanxiong rheumatic arthralgia, lump in the abdomen caking, skin infection swells and ache; Alumen expectorant, dampness, antidiarrheal, hemostasis, removing toxic substances, parasite killing, removes the rotten and lets fresh grow; Salicylic acid, phenol pain relieving, itch stopping and diminish inflammation, suppress smegma, increases sebum glandular orifice open; All medicine synergism above, scientific and reasonable compatibility, brings out the best in each other, and gos deep into focus, to reach therapeutic purposes.
Indication of the present invention: acne, acne infection and cicatrix disease disease.
Instructions of taking: the coating of usual amounts affected part, every day 2 ~ 3 times.
The present invention can will mention superficial part by the skin deep part of acne, acne infection and cicatrix disease, and superficial part is mentioned external, and last ecchymosis disappears, more after no longer recurrence, greatly improved immune function of human body, more after preventing from scar.Particularly various antibiotic therapy local skins are infected in invalid situation, therapeutic effect of the present invention is still remarkable, and cure rate is high.
With regard to clinical effectiveness of the present invention, further illustrate curative effect of the present invention below:
Criterion:
Clinical recovery---symptom disappears completely, and main physico-chemical examination index is normal.
Effectively---cardinal symptom disappears, and pathological changes area diminishes, and main physical and chemical index makes moderate progress.
Invalid---compared with before treatment, each side is all without improving.
Clinical statistics application T statistical theory is treated recovery from illness 90 examples (90%), effective 8 examples (8%), invalid 2 examples (2%) to the patient of the local skin infection of 100 routine different parts skin.
Good effect of the present invention is: take pure Chinese herbal medicine as raw material, through science preparation, have very strong anti-inflammatory analgetic ability, without skin allergy phenomenon, occur, treatment cycle is short, after healing, do not rebound, and wide accommodation, curative effect is reliable, has no side effect.
the specific embodiment:
In following examples, will further illustrate the present invention, but not limit the present invention in any way.
embodiment 1
According to ointment processing technology traditional on pharmaceutics, Radix Angelicae Dahuricae 25g, Radix Angelicae Sinensis 25g, Myrrha 25g, Alumen 15g, Rhizoma Atractylodis Macrocephalae 15g, Herba Epimedii 15g, Poria 15g, Flos Lonicerae 15g, Fructus Forsythiae 15g, Bulbus Fritillariae Cirrhosae 10g, Squama Manis 8g, Rhizoma Chuanxiong 8g, Herba Menthae 5g etc. are pulverized to 100 ~ 120 order fine powders, add phenol 2g, salicylic acid 60g, emulsifiable paste matrix 1000g to stir, make mallorca acne Mallorca ointment; Concrete technology should meet 2000 editions unguentum project relevant requirements of Pharmacopoeia of People's Republic of China.
embodiment 2
Radix Angelicae Dahuricae 30g, Radix Angelicae Sinensis 30g, Myrrha 30g, Alumen 10g, Rhizoma Atractylodis Macrocephalae 10g, Herba Epimedii 10g, Poria 10g, Flos Lonicerae 13g, Fructus Forsythiae 13g, Bulbus Fritillariae Cirrhosae 13g, Squama Manis 5g, Rhizoma Chuanxiong 5g, Herba Menthae 3g etc. are pulverized to 100 ~ 120 order fine powders, add phenol 4g, salicylic acid 50g, emulsifiable paste matrix 800g to stir, according to ointment processing technology traditional on pharmaceutics, make mallorca acne Mallorca ointment; Concrete technology should meet 2000 editions unguentum project relevant requirements of Pharmacopoeia of People's Republic of China.
embodiment 3
Radix Angelicae Dahuricae 20g, Radix Angelicae Sinensis 20g, Myrrha 20g, Alumen 13g, Rhizoma Atractylodis Macrocephalae 13g, Herba Epimedii 13g, Poria 13g, Flos Lonicerae 10g, Fructus Forsythiae 10g, Bulbus Fritillariae Cirrhosae 10g, Squama Manis 10g, Rhizoma Chuanxiong 10g, Herba Menthae 5g etc. are pulverized to 100 ~ 120 order fine powders, add phenol 1g, salicylic acid 30g, emulsifiable paste matrix 500g to stir, make mallorca acne Mallorca ointment; Concrete technology should meet 2000 editions unguentum project relevant requirements of Pharmacopoeia of People's Republic of China.
embodiment 4
Golden Radix Angelicae Dahuricae 25g, Radix Angelicae Sinensis 25g, Myrrha 25g, Alumen 10g, Rhizoma Atractylodis Macrocephalae 10g, Herba Epimedii 15g, Poria 15g, Flos Lonicerae 10g, Fructus Forsythiae 10g, Bulbus Fritillariae Cirrhosae 10g, Squama Manis 5g, Rhizoma Chuanxiong 5g, Herba Menthae 3g etc. are pulverized to 100 ~ 120 order fine powders, add phenol 3g, salicylic acid 60g, emulsifiable paste matrix 600g to stir, make mallorca acne Mallorca ointment; Concrete technology should meet 2000 editions unguentum project relevant requirements of Pharmacopoeia of People's Republic of China.
by following model case, further show the curative effect of medicine of the present invention:
case 1
Wang, man, 30 years old, for many years, concurrent infection had 6 months to facial acne in the recent period, diagnosis: acne concurrent infection, is used multiple topical Retinoids class Drug therapy invalid; Coated medicine of the present invention (embodiment 1 medicine) is after one week, and symptom alleviates, and uses continuously one month, and facial area acne and infection all disappear, and follows up a case by regular visits to 6 months without bounce-back.
case 2
Zhang, female, 28 years old, civil servant, suffers from acne with rear face in 20 years old, serious gradually, so that there is the red pimple of large area in thoracic dorsal top and shoulder, seek curing and treat for many years without significant curative effect, body is looked into as hyperactivity of toxic heat type acne, and coated medicine of the present invention (embodiment 2 medicines) is after one week, the red pimple symptom of facial area acne and health alleviates, use one month continuously, facial area acne and infection all disappear, and follow up a case by regular visits to 6 months without bounce-back.
case 3
Lee, man, 25 years old, adolescence,, whole face acne was serious, and part infects, and coated medicine of the present invention (embodiment 3 medicines) is after one week, and symptom alleviates, and makes continuously two months, and facial area acne and infection all disappear, and follow up a case by regular visits to 6 months without bounce-back.

Claims (3)

1. a treatment comedo acne compound recipe ointment, it is characterized in that being made by ratio of weight and the number of copies by following medicine:
The Radix Angelicae Dahuricae 20 ~ 30, Radix Angelicae Sinensis 20 ~ 30, Myrrha 20 ~ 30, Alumen 10 ~ 15, the Rhizoma Atractylodis Macrocephalae 10 ~ 15, Herba Epimedii 10 ~ 15, Poria 10 ~ 15, Flos Lonicerae 10 ~ 15, Fructus Forsythiae 10 ~ 15, Bulbus Fritillariae Cirrhosae 10 ~ 15, Squama Manis 5 ~ 10, Rhizoma Chuanxiong 5 ~ 10, Herba Menthae 3 ~ 5, phenol 1 ~ 4, salicylic acid 30 ~ 70, emulsifiable paste matrix 500 ~ 1000.
2. one according to claim 1 is treated comedo acne compound recipe ointment, and its optimum ratio is:
The Radix Angelicae Dahuricae 25, Radix Angelicae Sinensis 25, Myrrha 25, Alumen 15, the Rhizoma Atractylodis Macrocephalae 15, Herba Epimedii 15, Poria 15, Flos Lonicerae 15, Fructus Forsythiae 15, Bulbus Fritillariae Cirrhosae 10, Squama Manis 8, Rhizoma Chuanxiong 8, Herba Menthae 5, phenol 2, salicylic acid 60, emulsifiable paste matrix 1000.
3. a kind of preparation technology who treats comedo acne compound recipe ointment according to claim 1 and 2, comprises the following steps:
The Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Myrrha, Alumen, the Rhizoma Atractylodis Macrocephalae, Herba Epimedii, Poria, Flos Lonicerae, Fructus Forsythiae, Bulbus Fritillariae Cirrhosae, Squama Manis, Rhizoma Chuanxiong, Herba Menthae are pulverized to 100 ~ 120 orders, add phenol, salicylic acid, emulsifiable paste matrix to stir and make compound ointment.
CN201410042597.6A 2014-01-29 2014-01-29 A kind of composite medical ointment for the treatment of acne Expired - Fee Related CN103735821B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105343352A (en) * 2015-12-16 2016-02-24 济南舜祥医药科技有限公司 Acne ointment applied to temples and preparation method thereof
CN105435116A (en) * 2015-12-28 2016-03-30 陈雯雯 Medicine used for treating acnes caused by blood heat

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1709322A (en) * 2005-06-15 2005-12-21 李德森 Compound ointment for treating acne
CN103272143A (en) * 2013-04-25 2013-09-04 孙胜波 Traditional Chinese medicine composition for treating acne

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1709322A (en) * 2005-06-15 2005-12-21 李德森 Compound ointment for treating acne
CN103272143A (en) * 2013-04-25 2013-09-04 孙胜波 Traditional Chinese medicine composition for treating acne

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
罗仁: "验方5则", 《江西中医药》, vol. 4, no. 4, 1 May 1993 (1993-05-01), pages 61 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105343352A (en) * 2015-12-16 2016-02-24 济南舜祥医药科技有限公司 Acne ointment applied to temples and preparation method thereof
CN105435116A (en) * 2015-12-28 2016-03-30 陈雯雯 Medicine used for treating acnes caused by blood heat

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Inventor after: Song Yingming

Inventor after: Zhu Yan

Inventor after: Li Yanhong

Inventor after: Sun Jifeng

Inventor after: Liu Yangyang

Inventor after: Yue Hong

Inventor after: Zheng Haizheng

Inventor after: Wang Chunhong

Inventor after: Chen Juan

Inventor before: Song Yingming

Inventor before: Zhu Yan

Inventor before: Li Yanhong

Inventor before: Sun Jifeng

Inventor before: Liu Yangyang

Inventor before: Yue Hong

Inventor before: Wang Chunhong

Inventor before: Chen Juan

COR Change of bibliographic data

Free format text: CORRECT: INVENTOR; FROM: SONG YINGMING ZHU YAN LI YANHONG SUN JIFENG LIU YANGYANG YUE HONG WANG CHUNHONG CHEN JUAN TO: SONG YINGMING ZHU YAN LI YANHONG SUN JIFENG LIU YANGYANG YUE HONG ZHENG HAIZHENG WANG CHUNHONG CHEN JUAN

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Granted publication date: 20151118

Termination date: 20170129