A kind of nourishing the liver tea electuary that prevents alcoholic liver
Technical field
The invention belongs to the nutraceutical field.
Background technology
Modern medicine is thought, the excessive drinking health risk, and every day drunk 100 grams (2 liang) by 40 ° of liquor, and general one-year age is promptly suffered from alcoholic liver, the liver fibrosis of had slight.In the actual life, drink 2 liang of liquor persons every day and can be found everywhere, this habits and customs grievous injury masses' is healthy.The people got alcoholic liver, should go to hospital to see the doctor, and followed the doctor's advice to take medicine treatment.This point must be affirmed.Present problem is, the custom of drinking is arranged, but or the drink amount so greatly, perhaps be not to drink everyday, perhaps only have the beer and do not drink liquor or the like, this situation is much.The masses need a kind of nutraceutical of nourishing the liver, support beneficial liver, the prevention alcoholic liver.The nutraceutical of nourishing the liver in the market is also few, also exist simultaneously effect inadequately obviously, the slower problem that takes effect, the masses do not feel quite pleased this.
To problem set forth above, the present invention provides a kind of nutraceutical nourishing the liver tea electuary that prevents alcoholic liver, and it has the reinforcing of setting upright, and nourishing qi and blood is promoting blood circulation and removing blood stasis, tonifies the liver and kidney, and the effect of prevention alcoholic liver has advantage effective, instant effect.
Summary of the invention
The present invention realizes through following technical scheme:
1, a kind of nourishing the liver tea electuary that prevents alcoholic liver adopts the preparation of Chinese medicine material and nutraceutical, and the weight proportion of Chinese medicine material and nutraceutical is:
Ligusticum wallichii 3---10 parts of 5 parts of black tea 5---9 parts of crusts 6---
Glossy ganoderma 6---5 parts of 10 portions of arillus longans 4---7 portions of fruit ofs Chinese magnoliavine 3---
The nourishing the liver tea electuary of this prevention alcoholic liver is processed by following method:
(1) by above-mentioned weight ratio, black tea with in the acid water that adds pH value 4 ~ 5 at 1: 15, is boiled 30min under 120 ℃, filter, merge filtrating twice, concentrate, activated carbon decolorizing, centrifugation, vacuum drying, extract Tea Polyphenols fine powder;
(2) by above-mentioned weight ratio, crust is extracted shitosan, manufacture craft is: crust is pulverized, added sig water, protein is separated with insoluble matter; In insoluble matter, add 10% watery hydrochloric acid, make wherein calcium phosphate be dissolved into calcium chloride, centrifugation, washing, drying, thick chitin; Add 40% ~ 50% concentrated sodium hydroxide liquid, 110 ℃, 1h; With deacetylate, filtration, washing, vacuum drying get extract shitosan fine powder;
(3) by above-mentioned weight ratio, Ligusticum wallichii, glossy ganoderma, arillus longan, the fruit of Chinese magnoliavine are extracted through conventional water extraction process, process medicinal extract, oven dry is pulverized, and gets the extract fine powder;
(4) above-mentioned (1), (2), (3) extract fine powder are mixed, stir, process fine particle, the pouch of packing into, every pouch include extract fine powder 1.6 grams, process the nourishing the liver tea electuary of prevention alcoholic liver.
Chinese medicine in this prescription all is that medicine-food two-purpose food and the food that the Ministry of Public Health announces can be used kind.
The present invention is according to the folk tradition prescription, sets upright the theory of reinforcing, nourishing qi and blood, help liver according to the traditional Chinese medical science, develops meticulously.The traditional Chinese medical science is thought, positive unsaturated vapor, and the deficiency of vital energy deficiency of blood, the hepatic tissue microcirculation is poor, and blood supply insufficiency is an alcohol injury liver, and Fibrotic major reason appears in liver.Control to work as and set upright reinforcing, nourishing qi and blood, promoting blood circulation and removing blood stasis, the help liver.Glossy ganoderma, arillus longan are set upright reinforcing among the we, nourishing qi and blood, mental-tranquilization, enhancing body immunity; Ligusticum wallichii, black tea are promoting blood circulation and removing blood stasis, and glossy ganoderma, arillus longan and Ligusticum wallichii, black tea are associated with, and the prosperous hemapodium of gas is given birth to new blood, and the hemostasis of dispelling improves the hepatic tissue microcirculation, increases the hepatic tissue CBF, and this key of liver fibrosis occurs for the prevention alcoholic liver; 5 are intended to strengthen the liver function with crust, promote alcohol metabolism.Long-term heavy drinking can cause alcoholic fatty liver and cirrhosis.Alcohol becomes acetaldehyde after getting into liver under the effect of alcohol dehydrogenase, the toxic action of acetaldehyde causes that the people has a headache, feels sick etc., and part acetaldehyde becomes acetate, becomes the crucial harmful substance of liver fibrosis.The extract shitosan of crust can strengthen the liver function, obviously accelerates the alcohol metabolism effect, and it not only can reduce the concentration of acetaldehyde, and owing to make acetaldehyde be able to timely processing, acetate reduces relatively, thereby has prevented the formation of fatty liver and cirrhosis.The moon that is aided with fruit of Chinese magnoliavine nourish liver and kidney; Healthy tendency is protected in convergence admittedly, modern pharmacological research, and fruit of Chinese magnoliavine active ingredient schizandrin has the protection liver; Promote liver cell regeneration, strengthen the liver detoxification function and strengthen the adrenal cortex function, thereby the liver function that receives the alcohol injury is progressively recovered.Make a general survey of full side, all flavor compatibilities bring out the best in each other, and play the merit of setting upright reinforcing, nourishing qi and blood, tonifying the liver and kidney, prevent alcoholic liver altogether, have advantage effective, instant effect.
The specific embodiment
Through following embodiment the present invention is done and to specify:
1, get following prescription (weight is unit by gram):
Ligusticum wallichii 3000 gram black tea 5000 gram crusts 6000 grams
The glossy ganoderma 6000 gram arillus longans 4000 gram fruit ofs Chinese magnoliavine 3000 grams
Press predetermined weight, respectively black tea, crust are extracted, get the extract fine powder with the way of content of the present invention (1), (2); With conventional water extraction process Ligusticum wallichii, glossy ganoderma, arillus longan, the fruit of Chinese magnoliavine are extracted, process extract fine powder 1200 grams altogether, said extracted thing fine powder is mixed; Stir; Process fine particle, process nourishing the liver tea electuary 750 pouches of prevention alcoholic liver, every pouch nourishing the liver tea includes extract 1.6 grams.
2, get following prescription (weight is unit by gram)
Ligusticum wallichii 5000 gram black tea 9000 gram crusts 10000 grams
The glossy ganoderma 10000 gram arillus longans 7000 gram fruit ofs Chinese magnoliavine 5000 grams
By above-mentioned same method, process nourishing the liver tea electuary 1437 pouches, every pouch includes extract 1.6 grams.
3, get following prescription (by weight):
7 parts on 6 parts of crusts of 4 parts of black tea of Ligusticum wallichii
4 parts in 5 portions of fruit ofs Chinese magnoliavine of 7 portions of arillus longans of glossy ganoderma
By above-mentioned same method, process nourishing the liver tea electuary, every pouch includes extract 1.6 grams.
4, get following prescription (by weight):
9 parts on 8 parts of crusts of 4 parts of black tea of Ligusticum wallichii
4 parts in 6 portions of fruit ofs Chinese magnoliavine of 9 portions of arillus longans of glossy ganoderma
By above-mentioned same method, process nourishing the liver tea electuary, every pouch includes extract 1.6 grams.
Clinical data:
The present invention is an example with traditional Chinese medical science alcoholic liver, through 22 routine clinical observations.Selecting traditional Chinese medical science alcoholic liver is standard: the patient has for a long time, the history of heavy drinking, and last 3 year or more more than 2 liang 40 ° of liquor every days; Poor appetite, fatigue and weak, health are become thin; Slight or moderate liver fibrosis are arranged; Serum glutamic oxalacetic transaminase significantly increases, and glutamic-pyruvic transaminase is normal, ratio between two 2: 1 ~ 5: 1.As above symptom can be made a definite diagnosis.Making a definite diagnosis the object of observation, is the male sex all, does not have other serious disease.42 years old ~ 67 years old age, 56.9 years old mean age.
Efficacy determination:
Produce effects: stop excessive drinking; Transference cure---appetite is good, and fatigue and weak disappears, on one's body energetically; The improvement of becoming thin, physical comfort; 4 indexs of liver fibrosis inspection are all qualified; Glutamic-oxalacetic transaminease significantly descends, and ratio<2 of glutamic-pyruvic transaminase: 1.
Effectively: excessive drinking reduces, and poor appetite, fatigue and weak, health are become thin and alleviated to some extent; The GVG transaminase descends more than 10%.
Invalid: as to continue excessive drinking, the symptom no change.
During clinical testing, withdraw other medicines and nutrient and healthcare products, take the nourishing the liver tea electuary that embodiment of the present invention 2 is made, observing 6 months is 1 cycle.Instructions of taking: every day 2 times, each 1 pouch, every pouch include extract 1.6 gram, warm boiled water after meal, symptom promptly has alleviation after 2 months, take 6 months after, symptom is obviously alleviated.22 philtrums of clinical trial, produce effects 9 people, effective 10 people, invalid 3 people, total effective rate 86.3%.