CN103461591A - Food type liver-nourishing tea granule capable of preventing and controlling alcoholic liver - Google Patents

Food type liver-nourishing tea granule capable of preventing and controlling alcoholic liver Download PDF

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Publication number
CN103461591A
CN103461591A CN201310400733XA CN201310400733A CN103461591A CN 103461591 A CN103461591 A CN 103461591A CN 201310400733X A CN201310400733X A CN 201310400733XA CN 201310400733 A CN201310400733 A CN 201310400733A CN 103461591 A CN103461591 A CN 103461591A
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Prior art keywords
liver
ethanol
nourishing tea
extract
fine powder
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CN201310400733XA
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Chinese (zh)
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刘新壮
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Lvyuan Qiuzheng Technology Development Co Ltd
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Lvyuan Qiuzheng Technology Development Co Ltd
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Priority to CN201310400733XA priority Critical patent/CN103461591A/en
Publication of CN103461591A publication Critical patent/CN103461591A/en
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Abstract

The invention relates to a food type liver-nourishing tea granule capable of preventing and controlling alcoholic liver, and belongs to the nutritious foods. The food type liver-nourishing tea granule can achieve the purposes of good effect and quick effect taking. The food type liver-nourishing tea granule is prepared from Antrodia camphorata, valerian, American ginseng, prepared rehmannia roots, ginkgo leaf and the like. The food type liver-nourishing tea granule has the efficacies on strengthening the body resistance and archaeus, reinforcing qi, nourishing blood, promoting blood circulation by removing blood stasis, and preventing and controlling the alcoholic liver, and has the advantages of good effect and quick effect taking.

Description

A kind of food liver-nourishing tea electuary that prevents alcoholic liver
Technical field
The invention belongs to the nutraceutical field.
Background technology
Modern medicine is thought, the excessive drinking health risk.Every day drunk 100 grams (2 liang) by 40 ° of white wine, and general one-year age suffers from alcoholic liver, slight liver fibrosis occurs.In actual life, drink 2 liang of white wine persons every day and can be found everywhere, this habits and customs grievous injury masses' is healthy.The people obtained alcoholic liver, should go to hospital to see the doctor, and followed the doctor's advice to take medicine treatment.This point must be affirmed.Present problem is, the custom of drinking is arranged, but or the drink amount so not large, or be not to drink everyday, or only have the beer and do not drink white wine etc., this situation is much.Broad masses wish to support beneficial liver by the way of dietotherapy, the prevention alcoholic liver.But the nutraceutical of nourishing the liver in the market is also few, also exist simultaneously effect not obviously, the slower problem that takes effect, the masses do not feel quite pleased this.
For problem set forth above, the invention provides a kind of food liver-nourishing tea electuary that prevents alcoholic liver, it has the righting reinforcing, and nourishing qi and blood is promoting blood circulation and removing blood stasis, and the effect of prevention alcoholic liver, have advantages of effective, instant effect.
Summary of the invention
The present invention is achieved through the following technical solutions:
1, a kind of food liver-nourishing tea electuary that prevents alcoholic liver, adopt Chinese medicine material and raw-food material preparation, and the weight proportion of Chinese medicine material and raw-food material is:
3-5 parts of 4-7 portions of American Ginsengs of 4-7 parts of valerians of camphor tree sesame
3-6 parts of 3-6 parts of ginkgo leaves of prepared rhizome of rehmannia
The food liver-nourishing tea electuary of this prevention alcoholic liver is made by following method:
(1) by above-mentioned weight proportion, the camphor tree sesame is extracted to camphor tree sesame polysaccharide, technological process is as follows: the camphor tree sesame is broken into to graininess, crosses 40 mesh sieves, with 95 ℃ of lixiviate 4.5h of hot water of feed liquid mass ratio 1:20, lixiviate 2 times, leaching liquor decompression, concentrated, concentration 95% ethanol mixing, standing 11h, centrifugal with 3 times of volumes, then add concentration 75% ethanol, the precipitation polysaccharide, dry and pulverize to obtain camphor tree sesame polyoses extract fine powder;
(2) by above-mentioned weight proportion, ginkgo leaf is extracted, process is: after ginkgo leaf is cleaned to pulverizing, the 80 ℃ of lower reflux extraction 3h of concentration 70% ethanol by 12 times of amounts, extract 2 times; Extract through concentrated remove ethanol after, supernatant is passed into to the adsorption column that is filled with the ADS-15 resin and is adsorbed, to remove ginkgoic acid, then with concentration 70% ethanol, resolve, reclaim ethanol and concentrated after spray-drying, obtain ginko leaves flavone extract fine powder;
(3) by above-mentioned weight proportion, valerian to be extracted, process is: valerian is pulverized, cross 40 mesh sieves, with the benzinum backflow degreasing of feed liquid mass ratio 1:10 2 times, suction filtration, washing, then put into 40 ℃ of dry 1h of the air dry oven under condition; Adding concentration by feed liquid mass ratio 1:20 again is 60% ethanol, soaks 24h, and ultrasonic extraction 30min, let cool, and centrifugation is dried and pulverized to obtain the Valerian root P.E fine powder;
(4) by above-mentioned weight proportion, American Ginseng, prepared rhizome of rehmannia are extracted through conventional water extraction process, make medicinal extract, dry and pulverize, obtain the extract fine powder; Mix with above-mentioned (1), (2), (3) extract fine powder, stir, make fine particle, the pouch of packing into, every pouch includes extract fine powder 4.2 grams, makes the food liver-nourishing tea electuary of prevention alcoholic liver.
Raw material in this formula is all that medicine-food two-purpose food and the food that the Ministry of Public Health announces can be used kind.
The present invention is according to the folk tradition formula, meticulously develops.The traditional Chinese medical science is thought, positive unsaturated vapor, and the deficiency of vital energy deficiency of blood, the hepatic tissue microcirculation is poor, and blood supply insufficiency is alcohol injury liver, and Fibrotic major reason appears in liver, controls when the righting reinforcing, nourishing qi and blood is promoting blood circulation and removing blood stasis.In side, American Ginseng is longer than tonifying Qi, beneficial cloudy tonifying Qi, clearing heat and moistening dryness; Prepared rhizome of rehmannia is longer than and is enriched blood, enriching yin and nourishing kidney, replenishing blood and nourishing liver; Ginkgo leaf temperature lung is invigorated blood circulation, and the antibechic diuresis can suppress platelet aggregation; American Ginseng, prepared rhizome of rehmannia and ginkgo leaf mutual reinforcement between are use, qi-blood tonifying, and the prosperous hemapodium of gas strengthens immunity of organisms more effective.For long-term heavy drinker, the healthy vigorous effect that two aspects are arranged of immunity: the one, " removing " effect of immunity, remove the unnecessary rubbish such as lipid in blood, makes blood clean, good fluidity, the hepatic tissue blood supply is full, and microcirculation improves, thus the prevention liver fibrosis, the 2nd, " reparation " effect of immunity, repair impaired hepatic tissue, the fibrillatable occurred is eased, liver function obtains recovery to a certain extent.These 2 is all very important to preventing and treating alcoholic liver.Minister all can provide maintenance to liver with camphor tree sesame, valerian.The acute liver damage function that camphor tree sesame fructification and mycelium all have reduction alcohol to bring out, someone uses CCl 4per os brought out chronic hepatitis in 8 weeks continuously, and another group gave camphor tree sesame zymotic fluid 1g/kg from the 4th week, and latter's hepatitis situation is obviously improved, and 2g/kg dosage can suppress the hepatic fibrosis-renal tubular ectasia syndrome that N-nitrosodimethylamine causes; Valerian has the effect of protection liver, for CCl 4the rabbit of the hepatic injury caused, give 3 ~ 5g every day, through tests such as pathology section examination and transaminases, the protection liver effect of certain degree all arranged.The camphor tree sesame is use with valerian phase 5, and the former alleviates liver fibrosis, and the latter protects liver, have complementary advantages, and the effect stack, dietotherapy prevents and treats the alcoholic liver better effects if.Make a general survey of full side, all flavor compatibilities, bring out the best in each other, and plays altogether the merit of righting reinforcing, nourishing qi and blood, promoting blood circulation and removing blood stasis, prevention alcoholic liver, has advantages of effective, instant effect.
The specific embodiment
By following embodiment, the present invention is done and illustrates:
1, get following formula (weight is in grams as a unit):
Camphor tree sesame 4000 gram valerian 4000 gram American Ginseng 3000 grams
Prepared rhizome of rehmannia 3000 gram ginkgo leaf 3000 grams
Weight, extracted camphor tree sesame, ginkgo leaf, valerian respectively by the method for content of the present invention (1), (2), (3) in accordance with regulations; By the method for content of the present invention (4), American Ginseng, prepared rhizome of rehmannia are extracted; Make altogether extract fine powder 2040 grams, above-mentioned (1), (2), (3), (4) extract fine powder are mixed, stir, make fine particle, the pouch of packing into, make food liver-nourishing tea electuary 485 pouches of prevention alcoholic liver, and every pouch includes extract 4.2 grams.
2, get following formula (weight in grams as a unit)
Camphor tree sesame 7000 gram valerian 7000 gram American Ginseng 5000 grams
Prepared rhizome of rehmannia 5000 gram ginkgo leaf 5000 grams
By above-mentioned same method, make food liver-nourishing tea electuary 828 pouches of prevention alcoholic liver, every pouch includes extract 4.2 grams.
3, get following formula (by weight):
3 parts of 5 portions of American Ginsengs of 5 portions of valerians of camphor tree sesame
4 parts of 4 parts of ginkgo leaves of prepared rhizome of rehmannia
By above-mentioned same method, make the food liver-nourishing tea electuary of prevention alcoholic liver, every pouch includes extract 4.2 grams.
4, get following formula (by weight):
4 parts of 6 portions of American Ginsengs of 6 portions of valerians of camphor tree sesame
5 parts of 5 parts of ginkgo leaves of prepared rhizome of rehmannia
By above-mentioned same method, make the food liver-nourishing tea electuary of prevention alcoholic liver, every pouch includes extract 4.2 grams.
clinical data:
The present invention be take traditional Chinese medical science alcoholic liver as example, through 22 routine clinical observations.Selecting traditional Chinese medical science alcoholic liver is standard: the patient has for a long time, the history of heavy drinking, and more than 2 liang, last more than 3 years 40 ° of white wine every days; Poor appetite, fatigue and weak, health are become thin; Slight or moderate liver fibrosis are arranged; Serum glutamic oxalacetic transaminase significantly increases, and glutamic-pyruvic transaminase is normal, ratio between two 2: 1 ~ 5: 1.As above symptom, can make a definite diagnosis.Making a definite diagnosis the object of observation, is all the male sex, without other serious disease.42 years old ~ 67 years old age, 56.9 years old mean age.
Efficacy determination:
Produce effects: stop excessive drinking; Transference cure---appetite is good, and fatigue and weak disappears, with it energetically; The improvement of becoming thin, health is comfortable; Liver fibrosis checks that 4 indexs are all qualified; Glutamic-oxalacetic transaminease significantly descends, and ratio<2 of glutamic-pyruvic transaminase: 1.
Effectively: excessive drinking reduces, and poor appetite, fatigue and weak, health are become thin and alleviated to some extent; The GVG transaminase descends more than 10%.
Invalid: continue excessive drinking, symptom is unchanged.
During clinical testing, withdraw other medicines and nutrient and healthcare products, take the food liver-nourishing tea electuary of the prevention alcoholic liver of embodiment of the present invention 2 making, observing 6 months is 1 cycle.Instructions of taking: every day 1 time, each 1 pouch, every pouch includes extract 4.2 grams, warm boiled water after meal, after 2 months, symptom has alleviation, and after taking 6 months, symptom is obviously alleviated.In 22 people of clinical trial, produce effects 9 people, effective 10 people, invalid 3 people, total effective rate 86.3%.

Claims (1)

1. a food liver-nourishing tea electuary that prevents alcoholic liver, is characterized in that, described liver-nourishing tea electuary is to adopt Chinese medicine material and raw-food material preparation, and the weight proportion of Chinese medicine material and raw-food material is:
3-5 parts of 4-7 portions of American Ginsengs of 4-7 parts of valerians of camphor tree sesame
3-6 parts of 3-6 parts of ginkgo leaves of prepared rhizome of rehmannia
The food liver-nourishing tea electuary of this prevention alcoholic liver is made by following method:
(1) by above-mentioned weight proportion, the camphor tree sesame is extracted to camphor tree sesame polysaccharide, technological process is as follows: the camphor tree sesame is broken into to graininess, crosses 40 mesh sieves, with 95 ℃ of lixiviate 4.5h of hot water of feed liquid mass ratio 1:20, lixiviate 2 times, leaching liquor decompression, concentrated, concentration 95% ethanol mixing, standing 11h, centrifugal with 3 times of volumes, then add concentration 75% ethanol, the precipitation polysaccharide, dry and pulverize to obtain camphor tree sesame polyoses extract fine powder;
(2) by above-mentioned weight proportion, ginkgo leaf is extracted, process is: after ginkgo leaf is cleaned to pulverizing, the 80 ℃ of lower reflux extraction 3h of concentration 70% ethanol by 12 times of amounts, extract 2 times; Extract through concentrated remove ethanol after, supernatant is passed into to the adsorption column that is filled with the ADS-15 resin and is adsorbed, to remove ginkgoic acid, then with concentration 70% ethanol, resolve, reclaim ethanol and concentrated after spray-drying, obtain ginko leaves flavone extract fine powder;
(3) by above-mentioned weight proportion, valerian to be extracted, process is: valerian is pulverized, cross 40 mesh sieves, with the benzinum backflow degreasing of feed liquid mass ratio 1:10 2 times, suction filtration, washing, then put into 40 ℃ of dry 1h of the air dry oven under condition; Adding concentration by feed liquid mass ratio 1:20 again is 60% ethanol, soaks 24h, and ultrasonic extraction 30min, let cool, and centrifugation is dried and pulverized to obtain the Valerian root P.E fine powder;
(4) by above-mentioned weight proportion, American Ginseng, prepared rhizome of rehmannia are extracted through conventional water extraction process, make medicinal extract, dry and pulverize, obtain the extract fine powder; Mix with above-mentioned (1), (2), (3) extract fine powder, stir, make fine particle, the pouch of packing into, every pouch includes extract fine powder 4.2 grams, makes the food liver-nourishing tea electuary of prevention alcoholic liver.
CN201310400733XA 2013-09-06 2013-09-06 Food type liver-nourishing tea granule capable of preventing and controlling alcoholic liver Pending CN103461591A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104857060A (en) * 2015-05-13 2015-08-26 柳州市耕青科技有限公司 Traditional Chinese medicine prescription for relieving drunken symptom

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102552631A (en) * 2012-02-20 2012-07-11 山东大学威海分校 Chinese herbal preparation having protective effect on alcoholic hepatic injury
CN102669345A (en) * 2012-05-20 2012-09-19 北京绿源求证科技发展有限责任公司 Brain nourishing nutrition food of brain nourishing tea granule
CN103229872A (en) * 2013-05-10 2013-08-07 北京绿源求证科技发展有限责任公司 Anti-aging food health-care tea electuary

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102552631A (en) * 2012-02-20 2012-07-11 山东大学威海分校 Chinese herbal preparation having protective effect on alcoholic hepatic injury
CN102669345A (en) * 2012-05-20 2012-09-19 北京绿源求证科技发展有限责任公司 Brain nourishing nutrition food of brain nourishing tea granule
CN103229872A (en) * 2013-05-10 2013-08-07 北京绿源求证科技发展有限责任公司 Anti-aging food health-care tea electuary

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Title
宋方方等: "银杏叶提取物预防大鼠酒精性肝损伤的机制研究", 《营养学报》 *
陶文沂等: "《药食用真菌生物技术》", 30 September 2007, 化学工业出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104857060A (en) * 2015-05-13 2015-08-26 柳州市耕青科技有限公司 Traditional Chinese medicine prescription for relieving drunken symptom

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Application publication date: 20131225