CN102580049B - Externally applied traditional Chinese medicine combination for treating osteoarthritis through applying iontophoresis and preparation method - Google Patents
Externally applied traditional Chinese medicine combination for treating osteoarthritis through applying iontophoresis and preparation method Download PDFInfo
- Publication number
- CN102580049B CN102580049B CN201210083840XA CN201210083840A CN102580049B CN 102580049 B CN102580049 B CN 102580049B CN 201210083840X A CN201210083840X A CN 201210083840XA CN 201210083840 A CN201210083840 A CN 201210083840A CN 102580049 B CN102580049 B CN 102580049B
- Authority
- CN
- China
- Prior art keywords
- radix
- parts
- aconiti preparata
- osteoarthritis
- iontophoresis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 title claims abstract description 43
- 201000008482 osteoarthritis Diseases 0.000 title claims abstract description 30
- 238000002360 preparation method Methods 0.000 title claims abstract description 20
- 241000903946 Clematidis Species 0.000 claims abstract description 15
- 229940079593 drug Drugs 0.000 claims abstract description 13
- 239000002994 raw material Substances 0.000 claims abstract description 13
- 241000218176 Corydalis Species 0.000 claims abstract description 12
- 239000004863 Frankincense Substances 0.000 claims abstract description 12
- 238000002156 mixing Methods 0.000 claims abstract description 9
- 238000001914 filtration Methods 0.000 claims abstract description 8
- 239000000203 mixture Substances 0.000 claims description 27
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 241000717739 Boswellia sacra Species 0.000 claims description 11
- 241001057584 Myrrha Species 0.000 claims description 11
- 229940126678 chinese medicines Drugs 0.000 claims description 7
- 238000004321 preservation Methods 0.000 claims description 4
- 230000000694 effects Effects 0.000 abstract description 19
- 239000013505 freshwater Substances 0.000 abstract 2
- 238000002791 soaking Methods 0.000 abstract 2
- 235000003717 Boswellia sacra Nutrition 0.000 abstract 1
- 240000007551 Boswellia serrata Species 0.000 abstract 1
- 235000012035 Boswellia serrata Nutrition 0.000 abstract 1
- 240000007311 Commiphora myrrha Species 0.000 abstract 1
- 235000006965 Commiphora myrrha Nutrition 0.000 abstract 1
- 241001071795 Gentiana Species 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 244000018716 Impatiens biflora Species 0.000 abstract 1
- 235000015912 Impatiens biflora Nutrition 0.000 abstract 1
- 241000112528 Ligusticum striatum Species 0.000 abstract 1
- 235000007265 Myrrhis odorata Nutrition 0.000 abstract 1
- 241000304195 Salvia miltiorrhiza Species 0.000 abstract 1
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 abstract 1
- 235000005155 Tanacetum balsamita Nutrition 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 244000237330 gutta percha tree Species 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 description 10
- 238000000034 method Methods 0.000 description 8
- 208000006820 Arthralgia Diseases 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 230000001737 promoting effect Effects 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 4
- 210000000629 knee joint Anatomy 0.000 description 4
- 210000000988 bone and bone Anatomy 0.000 description 3
- 238000005728 strengthening Methods 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 230000007850 degeneration Effects 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 206010005963 Bone formation increased Diseases 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- MFYSYFVPBJMHGN-ZPOLXVRWSA-N Cortisone Chemical compound O=C1CC[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 MFYSYFVPBJMHGN-ZPOLXVRWSA-N 0.000 description 1
- 208000012659 Joint disease Diseases 0.000 description 1
- 208000003947 Knee Osteoarthritis Diseases 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 206010048873 Traumatic arthritis Diseases 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000001716 anti-fugal effect Effects 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- 210000001188 articular cartilage Anatomy 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 239000003181 biological factor Substances 0.000 description 1
- 210000000845 cartilage Anatomy 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000003412 degenerative effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 230000010224 hepatic metabolism Effects 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 210000003041 ligament Anatomy 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000007634 remodeling Methods 0.000 description 1
- 201000003068 rheumatic fever Diseases 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 108010048734 sclerotin Proteins 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000008727 tongluo Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Abstract
The invention provides externally applied traditional Chinese medicine combination for treating osteoarthritis through applying iontophoresis and a preparation method. The externally applied traditional Chinese medicine combination is prepared by the following raw materials in parts by weight: 55-65 parts of large-leaved gentian, 55-65 parts of radix clematidis, 45-55 parts of radix angelicae pubescentis, 45-55 parts of garden balsam stem, 55-65 parts of radix aconiti preparata, 15-25 parts of rhizoma zingiberis, 25-35 parts of ligusticum wallichii, 25-35 parts of frankincense, 25-35 parts of myrrh, 25-35 parts of salvia miltiorrhiza, 25-35 parts of rhizoma corydalis, 25-35 parts of radix achyranthis bidentatae, 15-25 parts of eucommia ulmoides and 15-25 parts of liquorice. The preparation method comprises the following steps of: firstly soaking the radix aconiti preparata by fresh water for 35-45 minutes; soaking other medicines by a proper amount of fresh water; simultaneously, firstly decocting the radix aconiti preparata for 35-45 minutes; mixing and decocting the radix aconiti preparata and the other traditional Chinese medicines; boiling through high heat; decocting for 25-35 minutes through slow fire; pouring out and filtering; decocting for two times; mixing; and refrigerating for standby after concentrating. The externally applied traditional Chinese medicine combination for treating the osteoarthritis through applying the iontophoresis has the advantages of high cure rate, good curative effect, low treatment expense and little side effect.
Description
Technical field
The invention belongs to medical technical field, relate to the external application Chinese medicine for the treatment of osteoarthritis, is a kind of external medicine composition and preparation method of applying the iontophoresis osteoarthritis specifically.
Background technology
Osteoarthritis (ostoarthritis, OA) is a kind ofly take Articular cartilage degeneration and Secondary cases hyperosteogeny as the chronic joint disease of feature, to be more common in middle-aged and elderly people, and the women is more than the male.Be apt to occur in the larger joints such as knee joint hip of heavy burden, this disease also is called osteoarthritis, degenerative osteoarthritis, proliferative arthritis etc.Its pathogenic factor is not yet fully clear so far, is commonly considered as multiple paathogenic factor, comprises that due to the interaction of mechanicalness and biological factor, wherein the age is main high risk factor, and other factors comprise wound, obesity, heredity, metabolism etc.
Osteoarthritis belongs to " damp arthralgia ", " arthralgia aggravated by cold " category in the arthromyodynia of the traditional Chinese medical science, and is closely related with wind-cold damp pathogen.The Therapeutic Principle is expelling wind and removing dampness, dispersing cold for relieving pain, blood circulation promoting and blood stasis dispelling, Tongluo Shujin, strengthening the tendons and bones.Through our clinical practice of nearly 20 years, update in conjunction with prescription at all times, sum up external medicine composition and the preparation method of used application iontophoresis method treatment osteoarthritis.
Medicine-inductiveness is the method for the treatment of in human body that medicine ion imported by complete skin by unidirectional current, different pharmaceutical can stay a few hours to tens of days at the skin internal memory, it and drug level, current intensity, be directly proportional conduction time, this therapy does not need pipe intestinal digesting to absorb, after liver metabolism by blood distribution whole body, but through focus, its elsewhere of health does not have medicine, thereby farthest reduced side effects of pharmaceutical drugs and waste, be called green remedy by the world today.
The external application Chinese medicine cure rate of existing treatment osteoarthritis is lower, curative effect is undesirable, the external medicine composition and the preparation method that are fit to treat with the method for iontophoresis osteoarthritis are not yet arranged at present, therefore, how to configure the external medicine composition that is fit to treat with the method for iontophoresis osteoarthritis, make that its cure rate is high, good effect, medical expense is low, side effect is little, this is the technical problem that present the art needs to be resolved hurrily.
Summary of the invention
The problem that the present invention exists for solving prior art, provide a kind of external medicine composition and preparation method of applying the iontophoresis osteoarthritis, makes that its cure rate is high, good effect, medical expense is low, side effect is little.
The objective of the invention is to be achieved through the following technical solutions: a kind of external medicine composition of applying the iontophoresis osteoarthritis is characterized in that being made by each raw material of following weight portion:
Radix Gentianae Macrophyllae 55-65, Radix Clematidis 55-65, Radix Angelicae Pubescentis 45-55, Herba speranskiae tuberculatae 45-55, Radix Aconiti Preparata 55-65, Rhizoma Zingiberis 15-25, Rhizoma Chuanxiong 25-35, Olibanum 25-35, Myrrha 25-35, Radix Salviae Miltiorrhizae 25-35, Rhizoma Corydalis 25-35, Radix Achyranthis Bidentatae 25-35, Cortex Eucommiae 15-25 and Radix Glycyrrhizae 15-25.
Preferably, the concrete weight portion of each raw material is: Radix Gentianae Macrophyllae 60, Radix Clematidis 60, Radix Angelicae Pubescentis 50, Herba speranskiae tuberculatae 50, Radix Aconiti Preparata 60, Rhizoma Zingiberis 20, Rhizoma Chuanxiong 30, Olibanum 30, Myrrha 30, Radix Salviae Miltiorrhizae 30, Rhizoma Corydalis 30, Radix Achyranthis Bidentatae 30, the Cortex Eucommiae 20 and Radix Glycyrrhizae 20.
A kind of preparation method of applying the external medicine composition of iontophoresis osteoarthritis, its feature exists
In comprising the steps:
(1) by each raw material of following parts by weight:
Radix Gentianae Macrophyllae 55-65, Radix Clematidis 55-65, Radix Angelicae Pubescentis 45-55, Herba speranskiae tuberculatae 45-55, Radix Aconiti Preparata 55-65, Rhizoma Zingiberis 15-25, Rhizoma Chuanxiong 25-35, Olibanum 25-35, Myrrha 25-35, Radix Salviae Miltiorrhizae 25-35, Rhizoma Corydalis 25-35, Radix Achyranthis Bidentatae 25-35, Cortex Eucommiae 15-25 and Radix Glycyrrhizae 15-25.
(2) after first Radix Aconiti Preparata being soaked 35-45 minute with clear water, more appropriate clear water is soaked other drug, Radix Aconiti Preparata 35-45 minute simultaneously is decocted first, rear mix friedly with other Chinese medicines, intense fire is fried open rear 25-35 minute at a simmer, pours out filtration, decoct altogether twice, after mixing, concentrated cold preservation is standby.
Preferably, the concrete weight portion of each raw material is: Radix Gentianae Macrophyllae 60, Radix Clematidis 60, Radix Angelicae Pubescentis 50, Herba speranskiae tuberculatae 50, Radix Aconiti Preparata 60, Rhizoma Zingiberis 20, Rhizoma Chuanxiong 30, Olibanum 30, Myrrha 30, Radix Salviae Miltiorrhizae 30, Rhizoma Corydalis 30, Radix Achyranthis Bidentatae 30, the Cortex Eucommiae 20 and Radix Glycyrrhizae 20.
Concrete preparation method is: after first Radix Aconiti Preparata being soaked 40 minutes with clear water, again appropriate clear water is soaked other drug, be decocted first Radix Aconiti Preparata simultaneously about 40 minutes, mix fried with other Chinese medicines afterwards, intense fire is fried open rear about 30 minutes at a simmer, pour out filtration, decoct altogether twice, after mixing, concentrated cold preservation is standby.
The present invention compared with prior art has following advantage and good effect:
Chinese medicine of the present invention is the external medicine composition that is fit to treat with the method for iontophoresis osteoarthritis, and the Chinese medicine composition of the present invention's preparation, due to reasonable recipe, local drug concentration is large, has an onset rapid, determined curative effect, treat comfortable, the characteristics that patient is easy to accept.Be applicable to osteoarthritis, traumatic arthritis, rheumatic arthritis etc.Have that cure rate is high, good effect, medical expense is low, side effect is little, the medicine source is wide characteristics, preparation method is simple, convenient.The present invention has filled up specially and has treated the external medicine composition of osteoarthritis and the blank of preparation method for the method for iontophoresis, because the method treatment of iontophoresis is lacked than method dosages such as traditional oral Chinese medicine or medicines for external application, curative effect is fast, has reduced patient's financial burden.
From year June in June, 2003 to 2010, apply external medicine composition treatment patient 275 people of iontophoresis osteoarthritis of the present invention, wherein clinical recovery 188 people, account for 68.4%.Base is 65 people more, account for 23.6%.20 people that take a turn for the better, account for 7%.Invalid 2 people, account for 1%.Reached clinical cure rate 92%, the effect of effective percentage 99%, do not wait in treatment time 1-20 days, and from therapeutic effect, the more long-acting fruit of therapeutic effect is better.
The specific embodiment
A kind of embodiment of applying the external medicine composition of iontophoresis osteoarthritis of the present invention, press each raw material of following parts by weight: Radix Gentianae Macrophyllae 55-65, Radix Clematidis 55-65, Radix Angelicae Pubescentis 45-55, Herba speranskiae tuberculatae 45-55, Radix Aconiti Preparata 55-65, Rhizoma Zingiberis 15-25, Rhizoma Chuanxiong 25-35, Olibanum 25-35, Myrrha 25-35, Radix Salviae Miltiorrhizae 25-35, Rhizoma Corydalis 25-35, Radix Achyranthis Bidentatae 25-35, Cortex Eucommiae 15-25 and Radix Glycyrrhizae 15-25.
Embodiment 1:
Radix Gentianae Macrophyllae 65g, Radix Clematidis 55 g, Radix Angelicae Pubescentis 55 g, Herba speranskiae tuberculatae 45 g, Radix Aconiti Preparata 65 g, Rhizoma Zingiberis 15 g, Rhizoma Chuanxiong 35 g, Olibanum 25 g, Myrrha 35 g, Radix Salviae Miltiorrhizae 25 g, Rhizoma Corydalis 35 g, Radix Achyranthis Bidentatae 25 g, the Cortex Eucommiae 25 g and Radix Glycyrrhizae 15 g.
Embodiment 2:
Radix Gentianae Macrophyllae 60 g, Radix Clematidis 60 g, Radix Angelicae Pubescentis 50 g, Herba speranskiae tuberculatae 50 g, Radix Aconiti Preparata 60 g, Rhizoma Zingiberis 20 g, Rhizoma Chuanxiong 30 g, Olibanum 30 g, Myrrha 30 g, Radix Salviae Miltiorrhizae 30 g, Rhizoma Corydalis 30 g, Radix Achyranthis Bidentatae 30 g, the Cortex Eucommiae 20 g and Radix Glycyrrhizae 20 g.
Embodiment 3:
Radix Gentianae Macrophyllae 55 g, Radix Clematidis 65 g, Radix Angelicae Pubescentis 45 g, Herba speranskiae tuberculatae 55 g, Radix Aconiti Preparata 55 g, Rhizoma Zingiberis 25 g, Rhizoma Chuanxiong 25 g, Olibanum 35 g, Myrrha 25 g, Radix Salviae Miltiorrhizae 35 g, Rhizoma Corydalis 25 g, Radix Achyranthis Bidentatae 35 g, the Cortex Eucommiae 15 g and Radix Glycyrrhizae 25 g.
A kind of preparation method of applying the external medicine composition of iontophoresis osteoarthritis of the present invention, according to each raw material of the parts by weight in above-described embodiment.Specific embodiment is as follows:
Embodiment 4: the preparation method of the external medicine composition of application iontophoresis osteoarthritis comprises the steps:
(1) configure each raw material by embodiment 1 proportioning;
(2) after first Radix Aconiti Preparata being soaked 45 minutes with clear water, again appropriate clear water is soaked other drug, be decocted first Radix Aconiti Preparata simultaneously about 35 minutes, mix fried with other Chinese medicines afterwards, intense fire is fried open rear about 25 minutes at a simmer, pour out filtration, decoct altogether twice, be concentrated into after mixing 500ml let cool hide standby.
Embodiment 5: the preparation method of the external medicine composition of application iontophoresis osteoarthritis comprises the steps:
(1) configure each raw material by embodiment 2 proportionings;
(2) after first Radix Aconiti Preparata being soaked 40 minutes with clear water, again appropriate clear water is soaked other drug, be decocted first Radix Aconiti Preparata simultaneously about 40 minutes, mix fried with other Chinese medicines afterwards, intense fire is fried open rear about 30 minutes at a simmer, pour out filtration, decoct altogether twice, be concentrated into after mixing 500ml let cool hide standby.
Embodiment 6: the preparation method of the external medicine composition of application iontophoresis osteoarthritis comprises the steps:
(1) configure each raw material by embodiment 3 proportionings;
(2) after first Radix Aconiti Preparata being soaked 35 minutes with clear water, then clear water that will be appropriate immersion other drug, Radix Aconiti Preparata 45 minutes simultaneously is decocted first, rear mix friedly with other Chinese medicines, intense fire is fried open rear 35 minutes at a simmer, pours out filtration, decoct altogether twice, be concentrated into after mixing 500ml let cool hide standby.
The performance of each raw material of the present invention and effect and prescription analysis are as follows:
Radix Gentianae Macrophyllae, Radix Clematidis, Radix Angelicae Pubescentis, Herba speranskiae tuberculatae all have the effect of expelling wind and removing dampness, Radix Gentianae Macrophyllae: wind-damp dispelling, Shujin network, clearind deficient heat.Radix Clematidis: wind-damp dispelling, the meridian dredging, stopping numbness pain.Radix Clematidis is apt to away alter, the energy the meridian dredging, and wind-damp dispelling, analgesic effect is stronger.Radix Angelicae Pubescentis: the wind-damp dispelling pain relieving is induced sweat.Herba speranskiae tuberculatae: loose wind damp-clearing pain-relieving.Wherein Radix Gentianae Macrophyllae contains the alkaloid first and can make hypercorticalismus, and the secretion 17-hydroxy-11-dehydrocorticosterone increases, and impels arthritis to disappear, and Radix Clematidis has softening sclerotin effect, and antibiotic and antifungic action is both also all arranged.Radix Aconiti Preparata: wind-damp dispelling, cold expelling relieve the pain.Rhizoma Zingiberis can the cold of warp " send out all ".Rhizoma Chuanxiong: blood-activating and qi-promoting, dispeling the wind relieves the pain.Olibanum, Myrrha: promoting blood circulation to relieve pain, detumescence and promoting granulation.Radix Salviae Miltiorrhizae: blood circulation promoting and blood stasis dispelling, removing heat from blood eliminating carbuncle, blood-cooling and spirit-quieting.Rhizoma Corydalis: blood-activating and qi-promoting pain relieving.Radix Achyranthis Bidentatae: blood circulation promoting and blood stasis dispelling, tonifying liver and kidney and strengthening bones and muscles.The Cortex Eucommiae: invigorating the liver and kidney, bone and muscle strengthening.Radix Glycyrrhizae is regulated all medicines.
Model case:
Lee so-and-so, the female, 76 years old, two knee osteoarthritis 10 years, increased the weight of 5 days, walks the level road difficulty, the treatment first day after pain relief, can slowly walk at level road after second day, after 20 days, stair activity is normal.
Korea Spro so-and-so, the female, 72 years old, nearly 20 years of double knee joint pain, magnetic resonance shows that right knee cartilage ligament all has damage, can't take care of oneself, after treatment one course for the treatment of (10 days), can the level road walking, throw away crutch after two courses for the treatment of.
Zhao so-and-so, female, 52 years old, double knee joint pain nearly ten years, nearly January, the right gonalgia increased the weight of, and showed slightly swelling, the stair activity difficulty, and x-ray shows the double knee joint degeneration, treat sx↓ after 5 days, after two courses for the treatment of (20 days), pain and swelling disappear, normal operation.
Certainly, above-mentioned explanation is not the restriction to invention, and the present invention also is not limited to above-mentioned giving an example, those skilled in the art, and the variation of making in essential scope of the present invention, remodeling, interpolation or replacement, also should belong to protection scope of the present invention.
Claims (3)
1. an external medicine composition of applying the iontophoresis osteoarthritis, is characterized in that, by each raw material of following weight portion, made:
Radix Gentianae Macrophyllae 60, Radix Clematidis 60, Radix Angelicae Pubescentis 50, Herba speranskiae tuberculatae 50, Radix Aconiti Preparata 60, Rhizoma Zingiberis 20, Rhizoma Chuanxiong 30, Olibanum 30, Myrrha 30, Radix Salviae Miltiorrhizae 30, Rhizoma Corydalis 30, Radix Achyranthis Bidentatae 30, the Cortex Eucommiae 20 and Radix Glycyrrhizae 20.
2. a preparation method of applying the external medicine composition of iontophoresis osteoarthritis, is characterized in that, comprises the steps:
(1) by each raw material of following parts by weight:
Radix Gentianae Macrophyllae 60, Radix Clematidis 60, Radix Angelicae Pubescentis 50, Herba speranskiae tuberculatae 50, Radix Aconiti Preparata 60, Rhizoma Zingiberis 20, Rhizoma Chuanxiong 30, Olibanum 30, Myrrha 30, Radix Salviae Miltiorrhizae 30, Rhizoma Corydalis 30, Radix Achyranthis Bidentatae 30, the Cortex Eucommiae 20 and Radix Glycyrrhizae 20;
(2) after first Radix Aconiti Preparata being soaked 35-45 minute with clear water, more appropriate clear water is soaked other drug, Radix Aconiti Preparata 35-45 minute simultaneously is decocted first, rear mix friedly with other Chinese medicines, intense fire is fried open rear 25-35 minute at a simmer, pours out filtration, decoct altogether twice, after mixing, concentrated cold preservation is standby.
3. according to the preparation method of the external medicine composition of application iontophoresis osteoarthritis claimed in claim 2, it is characterized in that, concrete preparation process is: after first Radix Aconiti Preparata being soaked 40 minutes with clear water, again appropriate clear water is soaked other drug, be decocted first simultaneously Radix Aconiti Preparata about 40 minutes, mix fried with other Chinese medicines afterwards, intense fire is fried open rear about 30 minutes at a simmer, pour out filtration, decoct altogether twice, after mixing, concentrated cold preservation is standby.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210083840XA CN102580049B (en) | 2012-03-27 | 2012-03-27 | Externally applied traditional Chinese medicine combination for treating osteoarthritis through applying iontophoresis and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210083840XA CN102580049B (en) | 2012-03-27 | 2012-03-27 | Externally applied traditional Chinese medicine combination for treating osteoarthritis through applying iontophoresis and preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102580049A CN102580049A (en) | 2012-07-18 |
| CN102580049B true CN102580049B (en) | 2013-11-20 |
Family
ID=46469650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210083840XA Expired - Fee Related CN102580049B (en) | 2012-03-27 | 2012-03-27 | Externally applied traditional Chinese medicine combination for treating osteoarthritis through applying iontophoresis and preparation method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102580049B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104667421A (en) * | 2015-02-03 | 2015-06-03 | 李荣昌 | Efficient medicine-iontophoresis liquid bag and preparation and application methods thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101380453A (en) * | 2008-07-21 | 2009-03-11 | 刘翠侠 | Oral powder and external plaster for treating hyperosteogeny and atrophic arthritis and production method thereof |
| CN102188673A (en) * | 2010-03-17 | 2011-09-21 | 赵贵凤 | Plaster for promoting muscles and bones, and preparation and application thereof |
-
2012
- 2012-03-27 CN CN201210083840XA patent/CN102580049B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101380453A (en) * | 2008-07-21 | 2009-03-11 | 刘翠侠 | Oral powder and external plaster for treating hyperosteogeny and atrophic arthritis and production method thereof |
| CN102188673A (en) * | 2010-03-17 | 2011-09-21 | 赵贵凤 | Plaster for promoting muscles and bones, and preparation and application thereof |
Non-Patent Citations (4)
| Title |
|---|
| 孙丽英等.针刺加中药离子透入治疗退行性膝关节炎76例临床观察.《针灸临床杂志》.2000,第16卷(第02期),21-23. |
| 蔡秋生等.锐克痛拍击油外治风寒湿痹825例.《中医外治杂志》.1999,第8卷(第01期),24. |
| 针刺加中药离子透入治疗退行性膝关节炎76例临床观察;孙丽英等;《针灸临床杂志》;20000220;第16卷(第02期);21-23 * |
| 锐克痛拍击油外治风寒湿痹825例;蔡秋生等;《中医外治杂志》;19990217;第8卷(第01期);24 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102580049A (en) | 2012-07-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102488869B (en) | Traditional Chinese medicinal external-use liniment for muscle and bone ache | |
| CN102266541B (en) | Chinese medicinal plaster for treating hyperosteogeny or hyperosteogeny pain | |
| CN102294008A (en) | Chinese medicine for treating cervical spondylosis, lumbar disc herniation slipped disc, sciatica and femoral head lesion | |
| CN102836177B (en) | Traditional Chinese medicine preparation for treating osteopathia | |
| CN101804190B (en) | Tongbi cream for relieving rigidity of muscles and promoting blood circulation and preparation method thereof | |
| CN104288538A (en) | Plaster for treating neck, shoulder, waist and leg diseases and preparation method of plaster | |
| CN106039249A (en) | Unguent for treating rheumatism bone pain and preparation method thereof | |
| CN103263591A (en) | External-use medicine for treating neck/lumbar disc herniation and osteoarthropathy | |
| CN103520579A (en) | Medicinal liquor used for treating lumbocrural pain, hyperostosis and sciatica | |
| CN103860801A (en) | Plaster with capability of relaxing muscles and stimulating blood circulation and preparation method of plaster | |
| CN101249237B (en) | Chinese medicine bone fracture plaster and method of preparing the same | |
| CN102755622A (en) | Medicine for treating rheumatoid arthritis | |
| CN102743554B (en) | Externally applied plaster treating rheumatic arthralgia | |
| CN102580049B (en) | Externally applied traditional Chinese medicine combination for treating osteoarthritis through applying iontophoresis and preparation method | |
| CN104800463A (en) | Plaster for orthopaedics | |
| CN104096022A (en) | External use compound Chinese herbal preparation for treating ankylosing spondylitis and preparation method thereof | |
| CN105012901A (en) | Bone-infiltrating pain-eliminating liquid liniment for neck and waist | |
| CN101422531B (en) | Wind-expelling pain-assuaging paste capable of treating lumbar intervertebral disc protrusion | |
| CN102406870A (en) | Medicament for treating rheumatic arthralgia | |
| CN1400011A (en) | Chinese medicine ointment preparation for curing hyperosteogeny, pain and numbness and its production method | |
| CN101700395B (en) | Ointment for curing hyperosteogeny | |
| CN105770251A (en) | Tongning capsule for treatment of cervical spondylosis, lumbar diseases and arthritis | |
| CN104367679A (en) | Traditional Chinese medicine composition ointment for treating rheumatism and bone diseases | |
| CN101708324B (en) | Plaster used for treating femoral head necrosis and preparation method thereof | |
| CN101380425B (en) | Arthrosis pill |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C53 | Correction of patent for invention or patent application | ||
| CB02 | Change of applicant information |
Address after: Shinan District 266072 Shandong city of Qingdao province Ningxia Road 112, building 9, unit three, 301 households Applicant after: Fang Xuefeng Address before: 266042 Shandong city of Qingdao Province four flow Road No. 127 Qingdao Central Hospital Rehabilitation Department Applicant before: Fang Xuefeng |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CB03 | Change of inventor or designer information |
Inventor after: Gao Jun Inventor before: Fang Xuefeng Inventor before: Zhao Jie Inventor before: Wei Lili |
|
| CB03 | Change of inventor or designer information | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20171020 Address after: 301700 Tianjin city Wuqing District High Town College South Road No. 103 building -2-401 Caiwei NGA Patentee after: Gao Jun Address before: Shinan District 266072 Shandong city of Qingdao province Ningxia Road 112, building 9, unit three, 301 households Patentee before: Fang Xuefeng |
|
| TR01 | Transfer of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20131120 Termination date: 20180327 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |