CN102580035A - 一种治疗牙周炎的药剂 - Google Patents
一种治疗牙周炎的药剂 Download PDFInfo
- Publication number
- CN102580035A CN102580035A CN2012100676852A CN201210067685A CN102580035A CN 102580035 A CN102580035 A CN 102580035A CN 2012100676852 A CN2012100676852 A CN 2012100676852A CN 201210067685 A CN201210067685 A CN 201210067685A CN 102580035 A CN102580035 A CN 102580035A
- Authority
- CN
- China
- Prior art keywords
- parts
- medicament
- radix
- treating periodontitis
- periodontitis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 title claims abstract description 20
- 201000001245 periodontitis Diseases 0.000 title claims abstract description 20
- 241000628997 Flos Species 0.000 claims description 10
- 210000000582 semen Anatomy 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 4
- 241000206501 Actaea <angiosperm> Species 0.000 claims description 2
- 241000245240 Lonicera Species 0.000 claims description 2
- 239000007919 dispersible tablet Substances 0.000 claims description 2
- 239000002674 ointment Substances 0.000 claims description 2
- 239000003826 tablet Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 4
- 229940079593 drug Drugs 0.000 abstract description 2
- 241000906579 Actaea cimicifuga Species 0.000 abstract 1
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 235000017965 Asarum canadense Nutrition 0.000 abstract 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract 1
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 244000077995 Coix lacryma jobi Species 0.000 abstract 1
- 235000000385 Costus speciosus Nutrition 0.000 abstract 1
- 240000002948 Ophiopogon intermedius Species 0.000 abstract 1
- 241000913745 Spatholobus Species 0.000 abstract 1
- 241000606265 Valeriana jatamansi Species 0.000 abstract 1
- 244000273928 Zingiber officinale Species 0.000 abstract 1
- 235000006886 Zingiber officinale Nutrition 0.000 abstract 1
- 235000014687 Zingiber zerumbet Nutrition 0.000 abstract 1
- 235000005301 cimicifuga racemosa Nutrition 0.000 abstract 1
- 235000008397 ginger Nutrition 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 206010018276 Gingival bleeding Diseases 0.000 description 5
- 208000024283 Gingival haemorrhages Diseases 0.000 description 5
- 208000005888 Periodontal Pocket Diseases 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 210000004195 gingiva Anatomy 0.000 description 3
- 230000008961 swelling Effects 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 230000003239 periodontal effect Effects 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 241000606125 Bacteroides Species 0.000 description 1
- 208000006558 Dental Calculus Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 241000337665 Phatnoma Species 0.000 description 1
- 241000605008 Spirillum Species 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 208000037976 chronic inflammation Diseases 0.000 description 1
- 208000037893 chronic inflammatory disorder Diseases 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 208000007565 gingivitis Diseases 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
本发明涉及一种治疗牙周炎的药剂，它是由下述重量配比的物质制成：红花5-10份、升麻1-5份、干姜3-10份、鸡血藤5-10份、金银花1-5份、木香1-5份、薏苡仁5-15份、麦冬1-3份、甘草3-5份、当归1-5份和细辛1-5份。本发明所述的治疗牙周炎的药剂都采用天然药物制成疗效明确，可有效地治疗牙周炎，因此十分适宜在临床上推广。
Description
技术领域
本发明涉及医药领域，具体来说涉及一种治疗牙周炎的药剂。
背景技术
牙周炎是侵犯牙龈和牙周组织的慢性炎症，是一种破坏性疾病，其主要特征为牙周袋的形成及袋壁的炎症，牙槽骨吸收和牙齿逐渐松动，它是导致成年人牙齿丧失的主要原因。本病多因为菌斑，牙石，食物嵌塞，不良修复体，咬创伤等引起，牙龈发炎肿胀，同时使菌斑堆积加重，并由龈上向龈下扩延。由于龈下微生态环境的特点，龈下菌斑中滋生着大量毒力较大的牙周致病菌，如牙龈类杆菌，中间类杆菌，螺旋体等，使牙龈的炎症加重并扩延，导致牙周袋形成和牙槽骨吸收，造成牙周炎。因此，寻找一种有效地治疗牙周炎的药剂十分迫切。
发明内容
本发明的目的是提供一种治疗牙周炎的药剂。
为了实现本发明的目的，本发明提供一种治疗牙周炎的药剂，它是由下述重量配比的物质制成：红花5-10份、升麻1-5份、干姜3-10份、鸡血藤5-10份、金银花1-5份、木香1-5份、薏苡仁5-15份、麦冬1-3份、甘草3-5份、当归1-5份和细辛1-5份。
优选地，本发明所述的治疗牙周炎的药剂是由下述重量配比的物质制成：红花5份、升麻3份、干姜5份、鸡血藤8份、金银花3份、木香3份、薏苡仁10份、麦冬2份、甘草5份、当归3份和细辛5份。
更优选地，本发明所述的药剂为片剂、分散片、软膏剂、或漱口液。
本发明所述的治疗牙周炎的药剂都采用天然药物制成疗效明确，可有效地治疗牙周炎，因此十分适宜在临床上推广。
具体实施方式
下面通过实施例进一步说明本发明。应该理解的是，本发明的实施例是用于说明本发明而不是对本发明的限制。根据本发明的实质对本发明进行的简单改进都属于本发明要求保护的范围。除非另有说明，否则本发明中的百分数是重量百分数。
实施例漱口液的制备
取红花50克、升麻30克、干姜50克、鸡血藤80克、金银花30克、木香30克、薏苡仁100克、麦冬20克、甘草50克、当归30克和细辛50克，置于密封的烧瓶内，加入800克水，在80℃的水浴下加热3小时，过滤，收集滤液，杀菌消毒即得。
实验例
诊断标准参考中华医学会制定的《临床诊疗指南·口腔医学分册》的相关标准进行(中华医学会.临床诊疗指南·口腔医学分册.北京：人民卫生出版社，2004；25-26.)。即：①探诊深度＞3mm，有附着丧失＞1mm。②牙周袋表面牙龈可见红肿或探诊后可见出血。③X线片提示牙槽骨高度降低。
选取符合上述标准的30例患者，男15例，女15例；年龄17岁-44岁。
使用实施例1制备的漱口液来进行治疗，每次使用20ml进行漱口。每日3次。连续使用1周。
疗效标准
显效：牙龈出血溢脓肿痛消失，牙齿松动减轻，牙周袋深度下降2mm，牙龈指数下降一半，牙龈出血指数为0；好转：牙龈出血溢脓肿痛缓解，牙齿松动减轻，牙周袋深度下降1mm，牙龈出血指数为1；无效：牙龈出血溢脓肿痛症状未见明显改善，牙齿松动无减轻，牙周袋深度无下降。
结果
在共30例患者中，全部符合显效的疗效标准。
不良反应
对于30例患者在治疗过程中进行跟踪观察，未发现明显的不良反应。
Claims (3)
1.一种治疗牙周炎的药剂，其特征在于，它是由下述重量配比的物质制成：红花5-10份、升麻1-5份、干姜3-10份、鸡血藤5-10份、金银花1-5份、木香1-5份、薏苡仁5-15份、麦冬1-3份、甘草3-5份、当归1-5份和细辛1-5份。
2.根据权利要求1所述的治疗牙周炎的药剂，其特征在于，它是由下述重量配比的物质制成：红花5份、升麻3份、干姜5份、鸡血藤8份、金银花3份、木香3份、薏苡仁10份、麦冬2份、甘草5份、当归3份和细辛5份。
3.根据权利要求1或2所述的治疗牙周炎的药剂，其特征在于，所述药剂为片剂、分散片、软膏剂、或漱口液。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210067685 CN102580035B (zh) | 2012-03-15 | 2012-03-15 | 一种治疗牙周炎的药剂 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210067685 CN102580035B (zh) | 2012-03-15 | 2012-03-15 | 一种治疗牙周炎的药剂 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102580035A true CN102580035A (zh) | 2012-07-18 |
| CN102580035B CN102580035B (zh) | 2013-07-31 |
Family
ID=46469636
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201210067685 Expired - Fee Related CN102580035B (zh) | 2012-03-15 | 2012-03-15 | 一种治疗牙周炎的药剂 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102580035B (zh) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103099950A (zh) * | 2013-01-09 | 2013-05-15 | 张大雷 | 一种治疗风火牙痛的中药制剂 |
| CN105106602A (zh) * | 2015-09-18 | 2015-12-02 | 全椒先奇医药科技有限公司 | 一种用于治疗牙周炎的药物制剂 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101744939A (zh) * | 2010-01-31 | 2010-06-23 | 张敏洁 | 预防口腔疾病和保健功效的中草药组合物及制备方法 |
| CN102133292A (zh) * | 2011-02-28 | 2011-07-27 | 王磊 | 一种治疗慢性牙周炎的口腔中药制剂及其制备方法 |
-
2012
- 2012-03-15 CN CN 201210067685 patent/CN102580035B/zh not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101744939A (zh) * | 2010-01-31 | 2010-06-23 | 张敏洁 | 预防口腔疾病和保健功效的中草药组合物及制备方法 |
| CN102133292A (zh) * | 2011-02-28 | 2011-07-27 | 王磊 | 一种治疗慢性牙周炎的口腔中药制剂及其制备方法 |
Non-Patent Citations (3)
| Title |
|---|
| 吴行明等: "王步希治疗牙痛", 《湖北中医杂志》 * |
| 孙海华: "中西医结合治疗急性牙周炎临床观察", 《中国中医急症》 * |
| 蔡淦等: "《实用中医脾胃病学》", 30 June 1996 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103099950A (zh) * | 2013-01-09 | 2013-05-15 | 张大雷 | 一种治疗风火牙痛的中药制剂 |
| CN105106602A (zh) * | 2015-09-18 | 2015-12-02 | 全椒先奇医药科技有限公司 | 一种用于治疗牙周炎的药物制剂 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102580035B (zh) | 2013-07-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100420432C (zh) | 漱口液及制备方法 | |
| CN102698103B (zh) | 一种治疗牙周炎的中药制剂 | |
| CN105411959A (zh) | 一种含有中草药的保健牙膏及其制备方法 | |
| CN102228417A (zh) | 含有薁磺酸钠的中草药牙膏组合物 | |
| CN102580035B (zh) | 一种治疗牙周炎的药剂 | |
| CN102727803B (zh) | 一种治疗牙周炎的药剂 | |
| CN102631448B (zh) | 一种治疗牙周炎的药剂 | |
| CN102309663B (zh) | 一种防治龋齿的药剂 | |
| CN102670891A (zh) | 一种治疗牙龈炎的药剂 | |
| CN102657743B (zh) | 一种治疗牙周炎的漱口液 | |
| CN102488770B (zh) | 一种治疗牙周炎的含漱液 | |
| CN102114084A (zh) | 一种用于治疗牙周炎的药物 | |
| CN103690752B (zh) | 一种治疗正畸牙龈炎的药剂 | |
| CN103656083B (zh) | 一种治疗肋软骨炎的中药组合物 | |
| CN103638319B (zh) | 一种治疗牙周炎的药物的制备方法 | |
| CN102895455B (zh) | 一种治疗牙周炎的药剂 | |
| CN103110926A (zh) | 一种治疗牙周炎的药剂 | |
| CN102727810B (zh) | 一种治疗牙龈炎的药物组合物 | |
| CN102657781B (zh) | 一种治疗牙周炎的喷雾剂 | |
| CN105687906A (zh) | 一种治疗牙周病的中药制剂及制备方法 | |
| CN104887917A (zh) | 一种治疗牙周炎的中药 | |
| CN102755527B (zh) | 一种用于牙齿松动的口服液 | |
| CN104644845B (zh) | 复方中药牙膏 | |
| CN103550373B (zh) | 一种治疗牙龈炎的药剂 | |
| CN103110924A (zh) | 一种治疗痔疮的药剂 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: SHI LAIXIN Free format text: FORMER OWNER: BU JIE Effective date: 20141231 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 272067 JINING, SHANDONG PROVINCE TO: 226400 NANTONG, JIANGSU PROVINCE |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20141231 Address after: 226400, building 501, building 12, green garden village, dug Town, Rudong County, Jiangsu Patentee after: Shi Laixin Address before: 272067 No. 16 Lotus Road, Shandong, Shandong Province, Jining Medical University, Jining Patentee before: Bu Jie |
|
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130731 Termination date: 20190315 |