CN102579938B - 一种治疗牙龈炎的喷雾剂 - Google Patents
一种治疗牙龈炎的喷雾剂 Download PDFInfo
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Abstract
本发明涉及一种治疗牙龈炎的喷雾剂，它是由下述重量配比的物质制成：金银花3-5份、五倍子5-15份、仙鹤草1-5份、白芷4-8份、荆芥1-5份、高良姜3-7份、裸花紫珠5-11份、茯苓3-5份和药学上可接受的载体。本发明所述的治疗牙龈炎的喷雾剂成分简单明确，消毒效果明显，并且采用喷雾剂剂型来使用，可以更好地治疗牙龈炎。
Description
技术领域
本发明涉及医药领域，具体来说涉及一种治疗牙龈炎的喷雾剂。
背景技术
牙龈炎是指牙齿组织在致病因素的作用下而发生的急、慢性炎症。医学上将围绕并覆盖在牙齿周围及槽突表面的口腔粘膜称之牙龈。由于几乎每人在一生的某个时期均会发生程度和范围不等的慢性牙龈炎，完全有理由说：牙龈炎是人类最常见的疾病。因此，迫切需要治疗牙龈炎的药物。
发明内容
本发明的目的是提供一种治疗牙龈炎的喷雾剂。
为了实现本发明的目的，本发明提供一种治疗牙龈炎的喷雾剂，它是由下述重量配比的物质制成：金银花3-5份、五倍子5-15份、仙鹤草1-5份、白芷4-8份、荆芥1-5份、高良姜3-7份、裸花紫珠5-11份、茯苓3-5份和药学上可接受的载体。
优选地，所述的治疗牙龈炎的喷雾剂是由下述重量配比的物质制成：金银花4份、五倍子10份、仙鹤草2份、白芷5份、荆芥2份、高良姜4份、裸花紫珠7份、茯苓4份和药学上可接受的载体。
喷雾剂是药物研究中开发的新剂型，其中药学上可接受的载体是指进行喷雾剂配制时常规使用的各种载体，这是本领域技术人员容易地意识到的。例如，药学上可接受的载体包括但不限于：抛射剂、芳香剂、抗氧化剂、稳定剂、药学上可接受的溶剂、吸收促进剂、药学上可接受的助溶剂等等。所述药学上可接受的载体的用量可以由本领域技术人员通过常规方法来确定。
本发明所述的治疗牙龈炎的喷雾剂成分简单明确，消毒效果明显，并且采用喷雾剂剂型来使用，可以更好地治疗牙龈炎。
具体实施方式
以下通过具体实施方式的描述对本发明作进一步说明，但这并非是对本发明的限制，本领域技术人员根据本发明的基本思想，可以做出各种修改或改进，但是只要不脱离本发明的基本思想，均在本发明的范围之内。
实施例1：本发明喷雾剂的制备
称取金银花40克、五倍子100克、仙鹤草20克、白芷50克、荆芥20克、高良姜40克、裸花紫珠70克、茯苓40克和水700毫升，置于密封的烧瓶内。在30℃的水浴下加热5小时，过滤，收集滤液，浓缩至500毫升。加入20克吐温-60、1克薄荷油和20毫升丙二醇，混合均匀，消毒，灌入50瓶喷雾器中即得。
实验例
选取患者30(男13，女17)例，年龄16-28岁。临床表现为患牙牙龈深红色或暗红色，松软光亮，眼沟出血指数(SBI)3～5，龈缘肥厚，龈乳头呈球状增生，甚至覆盖部分牙面，龈沟探诊深度(PD)＞3 mm，但未能探及釉牙骨质界；病程较长的患者牙龈颜色变浅，探诊出血减少，龈乳头和龈缘呈实质性肥大，质地较硬而有弹性。牙石(+～++)，严重者龈袋可有淡黄色渗出液或脓液溢出。
使用实施例1制备的喷雾剂来进行治疗，使用时每次在患者口腔内均匀喷完1瓶，每天喷3次，连续治疗7天为一个疗程。
疗效标准
1治愈：疼痛消失，牙龈无出血，肿胀消退，外观恢复正常；2显效：疼痛缓解，牙龈肿胀消退，外观基本恢复正常；3有效：疼痛减轻，牙龈肿胀减轻，外观有所改善；4无效：症状、体征无明显变化。
经过一个疗程的治疗，发现所有患者均符合治愈的标准。
Claims (1)
1.一种治疗牙龈炎的喷雾剂，其特征在于它是由下述重量配比的物质制成：金银花4份、五倍子10份、仙鹤草2份、白芷5份、荆芥2份、高良姜4份、裸花紫珠7份、茯苓4份、和药学上可接受的载体。
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101455627A (zh) * | 2009-01-08 | 2009-06-17 | 暨南大学 | 裸花紫珠提取物在口腔清洁产品中的应用 |
| CN101953903A (zh) * | 2010-09-13 | 2011-01-26 | 杨亚丽 | 一种治疗少儿牙龈炎的漱口液及其制备方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101455627A (zh) * | 2009-01-08 | 2009-06-17 | 暨南大学 | 裸花紫珠提取物在口腔清洁产品中的应用 |
| CN101953903A (zh) * | 2010-09-13 | 2011-01-26 | 杨亚丽 | 一种治疗少儿牙龈炎的漱口液及其制备方法 |
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