CN102579043B - Electric impedance imaging system with open electrode scanning mode - Google Patents
Electric impedance imaging system with open electrode scanning mode Download PDFInfo
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- CN102579043B CN102579043B CN201210044463.9A CN201210044463A CN102579043B CN 102579043 B CN102579043 B CN 102579043B CN 201210044463 A CN201210044463 A CN 201210044463A CN 102579043 B CN102579043 B CN 102579043B
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Abstract
The invention discloses an electric impedance imaging system with an open electrode scanning mode. Exciting electrodes introduce an excitation signal emitted from an excitation source into an imaging body; a first measurement electrode and a second measurement electrode carry out one-dimensional or two-dimensional scanning along the surface of the imaging body between the exciting electrodes; a measurement device collects measurement information of the imaging body through the first measurement electrode and the second measurement electrode, and transmits the measurement information to a microprocessor, and the microprocessor processes the measurement information and rebuilds an electric impedance distribution image of the imaging body. According to the electric impedance imaging system disclosed by the invention, limitation of the surface area of the imaging body to the mounting quantity of the first measurement electrode and the second measurement electrode is overcome, the density of arranged measurement electrodes is greatly improved by arrangement of the first measurement electrode and the second measurement electrode; useful information is increased; the ill-condition of rebuilding the electric impedance is improved; the imaging resolution ratio of the electric impedance (or impedance spectroscopy) is improved and the rebuilding quality of the image is also improved.
Description
Technical field
The present invention relates to biomedical imaging field, particularly a kind of electric impedance imaging system of opening scan electrode pattern.
Background technology
The electrical characteristics of biological tissue can reflect the physiological and pathological information of organism, show as: different biological tissues have different electrical impedance characteristicses; The impedance of biological tissue changes along with physiological activity; Between the impedance of pathological changes biological tissue and normal structure, there is larger difference.The electrical impedance imaging that the electrical impedance distribution of biological tissue of take is imageable target has important clinical value aspect the early diagnosis of the location for pathological tissues and disease.Its principle is to apply certain safe exciting current (or voltage) to imageable target, by voltage (or electric current) signal of measurement target tissue surface, obtains the electrical impedance distribution image of tested tissue body inside according to image rebuilding method.
In recent years, electric impedance imaging system because of its to human detection noinvasive, imaging device is simple and the advantage such as easy to operate is subject to extensive concern.Domestic and international many researcheres have been done deep research to electric impedance imaging system.The device of existing fixed in position point electrode, such as: Xu Guizhi etc.
[1]the bio-electrical impedance imaging device of 128 passages of design; CHENXIANG ability etc.
[2]the Multi-electrode electrical impedance tomography data acquisition system of design; Also there is array-type electrode design, such as: sand flood etc.
[3]a kind of electrode array sensor for electrical impedance imaging of design; He Wei etc.
[4]the increment magnifying type signal measuring device for electrical impedance imaging of design; Germany Te Fute university
[5]a kind of two arrays of electrodes array way proposing is for carrying out the equipment of electrical impedance imaging and method etc.Yet current electric impedance imaging system still faces the lower and not high present situation of imaging accuracy of imaging resolution, can not meet the needs of clinical diagnosis.This be because the essence that electrical impedance images is rebuild be by surface potential (or surface electrical potential difference) solve one nonlinear, owe fixed and pathosis inverse problem; Current electric impedance imaging system is all signal excitation and the drainage pattern that adopts fixed electrode mostly, referring to Fig. 1, take 16 electrodes as example, adjacent or the comparative electrode of take during measurement is exciting electrode, other electrodes are measurement electrode, obtain voltage (or electric current) information of other 14 location points, and this system is limit by imaging body surface area, the number of electrodes that can settle is limited, and this just makes less qualitative problem be difficult to improve; And because measurement electrode adopts even setting mostly, can not in the larger effective coverage of potential change, obtain more useful information.
List of references:
[1] a bio-electrical impedance imaging device for passage, publication number: CN201341881Y, open day: 2009.11.11;
[2] Multi-electrode electrical impedance tomography data acquisition system, open (bulletin) number: CN102274025A, open (bulletin) day: 2011.12.14;
[3] for an electrode array sensor for electrical impedance imaging, open (bulletin) number: CN2902191Y, open (bulletin) day: 2007.05.23;
[4] for an increment magnifying type signal measuring device for electrical impedance imaging, publication number: CN101125080A, discloses day: 2008.02.20;
[5] for carrying out equipment and the method for electrical impedance imaging, open (bulletin) number: CN101466303A, open (bulletin) day: 2009.06.24.
Summary of the invention
The present invention proposes a kind of electric impedance imaging system of opening scan electrode pattern, the present invention has realized and effectively in region, has extracted to a greater extent more metrical informations, thereby improves imaging resolution and imaging precision, described below:
An electric impedance imaging system of opening scan electrode pattern, comprising: pair of exciting, the first measurement electrode, the second measurement electrode, driving source, measuring device and microprocessor, wherein,
Described exciting electrode is fixedly installed in described imaging body, and the pumping signal that described exciting electrode sends described driving source is introduced described imaging body; Described the first measurement electrode and described the second measurement electrode are carried out the scanning of one dimension or two dimension between described exciting electrode along the surface of described imaging body; Described measuring device gathers the metrical information of described imaging body by described the first measurement electrode and described the second measurement electrode, and described metrical information is transferred to described microprocessor, described microprocessor is processed described metrical information, rebuilds the electrical impedance distribution image of described imaging body.
Described driving source is specially voltage source or current source.
Described driving source is specially the current source of single-frequency or a plurality of frequencies.
Described driving source is specially the voltage source of single-frequency or a plurality of frequencies.
Described the first measurement electrode and described the second measurement electrode are all movable end.
Described the second measurement electrode is fixed on the optional position on imaging body surface, and as with reference to electrode, described the first measurement electrode is movable end, and wherein said the first measurement electrode and described the second measurement electrode status are equal to.
Described the first measurement electrode and described the second measurement electrode are carried out one dimension or two dimension between described exciting electrode scanning along the surface of described imaging body is specially:
Described the first measurement electrode and described the second measurement electrode are carried out the equidistant scanning of one dimension or two dimension between described exciting electrode along the surface of described imaging body.
Described the first measurement electrode and described the second measurement electrode are carried out one dimension or two dimension between described exciting electrode scanning along the surface of described imaging body is specially:
Described the first measurement electrode and described the second measurement electrode are carried out the non-equidistance scanning of one dimension or two dimension between described exciting electrode along the surface of described imaging body.
The beneficial effect of technical scheme provided by the invention is:
The invention provides a kind of electric impedance imaging system of opening scan electrode pattern, the present invention is by replacing traditional sealing to measure with open local measurement, with scan electrode metering system, replace fixed electrode pattern, the electric impedance imaging system of the present invention's design is simple in structure, be easy to realize; The present invention has overcome imaging body surface area the first measurement electrode and the second measurement electrode has been settled to number quantitative limitation, and by the raising that very big degree is set of the first measurement electrode and the second measurement electrode the density of the measurement electrode of arranging, increase useful information, thereby improved the pathosis that electrical impedance is rebuild, improved the resolution of electrical impedance (or impedance spectrum) imaging; And by the first measurement electrode and the second measurement electrode, along the surface of imaging body, between exciting electrode, carry out the equidistant scanning of one dimension or two dimension, or non-equidistance scanning, improve the collecting efficiency of signal and the solution efficiency of microprocessor, improved the reconstruction quality of image.
Accompanying drawing explanation
Fig. 1 is traditional electrical impedance imaging electrode arrangement mode schematic diagram;
Fig. 2 is that the first measurement electrode provided by the invention and the second measurement electrode are all the scanning survey schematic diagram of movable end.
Fig. 3 is that the second measurement electrode provided by the invention is fixed on certain position as with reference to electrode, the scanning survey schematic diagram that the first measurement electrode is movable end;
In accompanying drawing, the list of parts of each label representative is as follows:
1: imaging body; 2,3: exciting electrode;
4: the first measurement electrode; 5: the second measurement electrode;
6: driving source; 7: measuring device;
8: microprocessor.
The specific embodiment
For making the object, technical solutions and advantages of the present invention clearer, below in conjunction with accompanying drawing, embodiment of the present invention is described further in detail.
In order realizing, effectively in region, to extract to a greater extent more metrical informations, thereby to improve imaging resolution and imaging precision, the embodiment of the present invention provides a kind of electric impedance imaging system of opening scan electrode pattern, described below:
Referring to Fig. 2 and Fig. 3, a kind of electric impedance imaging system of opening scan electrode pattern, comprising: pair of exciting 2,3, the first measurement electrode 4, the second measurement electrode 5, driving source 6, measuring device 7 and microprocessor 8, wherein,
Pair of exciting 2,3 is fixedly installed in imaging body 1, and the pumping signal that pair of exciting 2,3 is sent driving source 6 is introduced imaging body 1; The first measurement electrode 4 and the second measurement electrode 5 are carried out the scanning of one dimension or two dimension between exciting electrode 2,3 along the surface of imaging body 1; Measuring device 7 gathers the metrical information of imaging body 1 by the first measurement electrode 4 and the second measurement electrode 5, and metrical information is transferred to microprocessor 8, and 8 pairs of metrical informations of microprocessor are processed, the electrical impedance distribution image of reestablishment imaging body 1.
Further, in order to meet the multiple needs in practical application, the driving source 6 in the embodiment of the present invention is preferably voltage source or current source, can be current excitation voltage measurement, or voltage drive current measurement.Exciting electrode 2,3 pumping signals that driving source 6 is sent are introduced imaging body 1, imaging body 1 inside with certain electric impedance distribution will form specific electric current distribution, the first measurement electrode 4 and the second measurement electrode 5 along imaging body 1 surface at two exciting electrodes 2, between 3, carry out one dimension or two-dimensional movement scanning, can the voltage (or electric current) between the surperficial exciting electrode 2,3 of imaging body 1 be distributed and be measured.
Further, in order to meet the multiple needs in practical application, the driving source 6 in the embodiment of the present invention is preferably the current source of single-frequency or a plurality of frequencies.
Further, in order to meet the multiple needs in practical application, the driving source 6 in the embodiment of the present invention is preferably the voltage source of single-frequency or a plurality of frequencies.
Wherein, if the signal that driving source 6 is single-frequency can obtain the electrical impedance distribution of imaging body 1 by image rebuilding method; If driving source 6 is multifrequency signal, by the voltage under the different frequency measuring (or electric current), distributes and can obtain the impedance spectrum distributed image under different frequency.
Further, in order effectively to improve the density of arrange the first measurement electrode 4 and the second measurement electrode 5, increase useful information (data), thereby the spatial resolution that improves electrical impedance (spectrum) imaging, referring to Fig. 2, the embodiment of the present invention is preferably the first measurement electrode 4 and the second measurement electrode 5 is arranged on exciting electrode 2, between 3, the first measurement electrode 4 and the second measurement electrode 5 are all movable end, carry out the scanning of one dimension or two dimension along the surface of imaging body 1 between two exciting electrodes 2,3.
Further, in order effectively to improve the density of the measurement electrode 4 of arranging, increase useful information (data), thereby improve the spatial resolution of electrical impedance (spectrum) imaging, referring to Fig. 3, the embodiment of the present invention is preferably the first measurement electrode 4 and is arranged on exciting electrode 2, between 3, the second measurement electrode 5 is fixed on imaging body 1 optional position as with reference to electrode, and the first measurement electrode 4 is movable end, along the surface of imaging body 1, between exciting electrode 2,3, carry out the scanning of one dimension or two dimension.
In like manner, the embodiment of the present invention is preferably the second measurement electrode 5 and is arranged on exciting electrode 2, between 3, the first measurement electrode 4 is fixed on imaging body 1 optional position as with reference to electrode, the second measurement electrode 5 is movable end, along the surface of imaging body 1, between exciting electrode 2,3, carry out the scanning of one dimension or two dimension.
Further, in order to improve the collecting efficiency of signal and the solution efficiency of microprocessor, improve the reconstruction quality of image, the first measurement electrode 4 and the second measurement electrode 5 are carried out the equidistant scanning of one dimension or two dimension between exciting electrode 2,3 along the surface of imaging body 1.
Further, in order to improve the collecting efficiency of signal and the solution efficiency of microprocessor, improve the reconstruction quality of image, the first measurement electrode 4 and the second measurement electrode 5 along the surface of imaging body 1 at exciting electrode 2, between 3, carry out the non-equidistance scanning of one dimension or two dimension, can near exciting electrode 2,3, adopt fine and closely woven spacing scanning, away from exciting electrode 2,3 places, adopt thick spacing scanning.
Wherein, 8 pairs of metrical informations of microprocessor are processed, and the operation of the electrical impedance distribution image of reestablishment imaging body 1 can adopt the inferior method of improved newton's pressgang and filtered back-projection method etc., and during specific implementation, the embodiment of the present invention does not limit this.
Wherein, the embodiment of the present invention does not limit the model of measuring device 7 and microprocessor 8, according to the needs in practical application, selects.
With several specific embodiments, a kind of feasibility of opening the electric impedance imaging system of scan electrode pattern that the embodiment of the present invention provides is described below, described below:
When the first measurement electrode 4 and the second measurement electrode 5 scan for both-end, referring to Fig. 2, pumping signal is low-frequency current source, by exciting electrode 2 and 3, puts on imaging body 1.The first measurement electrode 4 and the second measurement electrode 5, between two exciting electrodes 2 and 3, are movable end.During measurement, the second measurement electrode 5 along imaging body 1 surface from original position 3 to the every mobile Yi Ge unit of final position 2, the first measurement electrode 4 all along imaging body 1 surface from original position 2 to final position 3 (for example: it is mobile that the first measurement electrode 4 from the position at exciting electrode 2 places is that original position starts, the position that moves to exciting electrode 3 places is final position) carry out single pass, the measurement electrode 4 and the voltage between measurement electrode 5 that obtain on this scanning route distribute, until moving, the second measurement electrode 5 arrives final position 2, the voltage that measuring device 7 records by the first measurement electrode 4 and the second measurement electrode 5 scannings distributes and transfers to microprocessor 8, microprocessor 8 is according to the electrical impedance distribution image of electrical impedance imaging method reestablishment imaging body 1.
Embodiment 2
When the single-ended scanning of the first measurement electrode 4, referring to Fig. 3, pumping signal is low-frequency current source, by exciting electrode 2 and 3, puts on imaging body 1.The first measurement electrode 4 is between two exciting electrodes 2 and 3, and the first measurement electrode 4 is movable end, and the second measurement electrode 5 is fixed on certain position of imaging body, as zero potentail reference.During measurement, measuring device 7 (for example: the first measurement electrode 4 is that original position starts to move from the position at exciting electrode 2 places scans from original position 2 to final position 3 along imaging body 1 surface by the first measurement electrode 4, the position that moves to exciting electrode 3 places is final position), the voltage obtaining on this scanning route distributes, measuring device 7 distributes voltage to transfer to microprocessor 8, and microprocessor 8 is according to the electrical impedance distribution image of electrical impedance imaging method reestablishment imaging body 1.
In sum, the embodiment of the present invention provides a kind of electric impedance imaging system of opening scan electrode pattern, the embodiment of the present invention is by replacing traditional sealing to measure with open local measurement, with scan electrode metering system, replace fixed electrode pattern, the electric impedance imaging system of embodiment of the present invention design is simple in structure, be easy to realize; The embodiment of the present invention has overcome imaging body surface area the first measurement electrode and the second measurement electrode has been settled to number quantitative limitation, and by the raising that very big degree is set of the first measurement electrode and the second measurement electrode the density of the measurement electrode of arranging, increase useful information, thereby improved the pathosis that electrical impedance is rebuild, improved the resolution of electrical impedance (or impedance spectrum) imaging; And by the first measurement electrode and the second measurement electrode, along the surface of imaging body, between exciting electrode, carry out the equidistant scanning of one dimension or two dimension, or non-equidistance scanning, improve the collecting efficiency of signal and the solution efficiency of microprocessor, improved the reconstruction quality of image.
It will be appreciated by those skilled in the art that accompanying drawing is the schematic diagram of a preferred embodiment, the invention described above embodiment sequence number, just to describing, does not represent the quality of embodiment.
The foregoing is only preferred embodiment of the present invention, in order to limit the present invention, within the spirit and principles in the present invention not all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (5)
1. an electric impedance imaging system of opening scan electrode pattern, is characterized in that, comprising: pair of exciting, the first measurement electrode, the second measurement electrode, driving source, measuring device and microprocessor, wherein,
Described exciting electrode is fixedly installed in imaging body, and the pumping signal that described exciting electrode sends described driving source is introduced described imaging body; Described the first measurement electrode and described the second measurement electrode are carried out the scanning of one dimension or two dimension between described exciting electrode along the surface of described imaging body;
Described the second measurement electrode is fixed on the optional position on imaging body surface, and as with reference to electrode, described the first measurement electrode is movable end, and wherein said the first measurement electrode and described the second measurement electrode status are equal to; Described measuring device scans from original position to final position along described imaging body surface by described the first measurement electrode, the voltage obtaining on this scanning route distributes, described measuring device distributes voltage to transfer to described microprocessor, and described microprocessor is rebuild the electrical impedance distribution image of described imaging body according to electrical impedance imaging method.
2. a kind of electric impedance imaging system of opening scan electrode pattern according to claim 1, is characterized in that, described driving source is voltage source or current source.
3. a kind of electric impedance imaging system of opening scan electrode pattern according to claim 2, is characterized in that, described driving source is the current source of single-frequency or a plurality of frequencies.
4. a kind of electric impedance imaging system of opening scan electrode pattern according to claim 2, is characterized in that, described driving source is the voltage source of single-frequency or a plurality of frequencies.
5. an electric impedance imaging system of opening scan electrode pattern, is characterized in that, comprising: pair of exciting, the first measurement electrode, the second measurement electrode, driving source, measuring device and microprocessor, wherein,
Described exciting electrode is fixedly installed in imaging body, and the pumping signal that described exciting electrode sends described driving source is introduced described imaging body; Described the first measurement electrode and described the second measurement electrode are carried out the scanning of one dimension or two dimension between described exciting electrode along the surface of described imaging body;
Described the first measurement electrode and described the second measurement electrode are all movable end, described the second measurement electrode along described imaging body surface from original position to the every mobile Yi Ge unit of final position, described the first measurement electrode is all carried out single pass along described imaging body surface from original position to final position, described the first measurement electrode and the voltage between described the second measurement electrode that obtain on this scanning route distribute, until described the second measurement electrode moves arrival final position, the voltage that described measuring device records by described the first measurement electrode and described the second measurement electrode scanning distributes and transfers to described microprocessor, described microprocessor is rebuild the electrical impedance distribution image of described imaging body according to electrical impedance imaging method.
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| CN104783800A (en) * | 2015-05-05 | 2015-07-22 | 天津工业大学 | Lung respiration monitoring system based on magnetic detection electrical impedance imaging |
| CN105030237A (en) * | 2015-07-17 | 2015-11-11 | 中国科学院电工研究所 | Spinal cord injury localization device |
| CN106037650B (en) * | 2016-06-13 | 2018-12-28 | 河北工业大学 | A kind of mixing variation biological electrical impedance tomography method |
| CN109745047B (en) * | 2019-01-22 | 2021-07-02 | 北京航空航天大学 | Electrical impedance imaging system based on piezoresistive electrode |
| CN114073511B (en) * | 2020-08-21 | 2023-11-14 | 北京华睿博视医学影像技术有限公司 | Excitation response measurement method, electrical impedance imaging method, and storage medium |
| CN112401866A (en) * | 2020-11-11 | 2021-02-26 | 中国科学技术大学 | Electrical impedance imaging method based on Boolean operation |
| WO2024127069A1 (en) | 2022-12-15 | 2024-06-20 | Ceske Vysoke Uceni Technicke V Praze | System for increasing precision of electric impedance tomography |
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| US7660617B2 (en) * | 2004-11-13 | 2010-02-09 | The Boeing Company | Electrical impedance tomography using a virtual short measurement technique |
| US20080027350A1 (en) * | 2006-07-13 | 2008-01-31 | Advanced Cardiovascular Systems, Inc. | Methods and apparatus for localization, diagnosis, contact or activity detection of bio-electric tissue |
| DE102008039844A1 (en) * | 2008-08-27 | 2010-03-04 | Fresenius Medical Care Deutschland Gmbh | Probe with at least two electrodes for impedance measurement, arrangement and method for this purpose |
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