CN102573960B - 用于药物递送装置的驱动机构 - Google Patents

用于药物递送装置的驱动机构 Download PDF

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Publication number
CN102573960B
CN102573960B CN201080043978.6A CN201080043978A CN102573960B CN 102573960 B CN102573960 B CN 102573960B CN 201080043978 A CN201080043978 A CN 201080043978A CN 102573960 B CN102573960 B CN 102573960B
Authority
CN
China
Prior art keywords
lead screw
screw nut
screw
main body
feature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201080043978.6A
Other languages
English (en)
Chinese (zh)
Other versions
CN102573960A (zh
Inventor
R.维齐
D.普伦普特里
C.琼斯
G.库约姆吉安
C.A.麦克唐纳德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Sanofi Aventis Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland GmbH filed Critical Sanofi Aventis Deutschland GmbH
Publication of CN102573960A publication Critical patent/CN102573960A/zh
Application granted granted Critical
Publication of CN102573960B publication Critical patent/CN102573960B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/31555Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/3156Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403Ampoule inserted into the ampoule holder
    • A61M2005/2407Ampoule inserted into the ampoule holder from the rear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501Means for blocking or restricting the movement of the rod or piston
    • A61M5/31505Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CN201080043978.6A 2009-09-30 2010-09-29 用于药物递送装置的驱动机构 Expired - Fee Related CN102573960B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09171765 2009-09-30
EP09171765.2 2009-09-30
PCT/EP2010/064425 WO2011039232A1 (en) 2009-09-30 2010-09-29 Drive mechanism for a drug delivery device

Publications (2)

Publication Number Publication Date
CN102573960A CN102573960A (zh) 2012-07-11
CN102573960B true CN102573960B (zh) 2014-12-10

Family

ID=41796059

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201080043978.6A Expired - Fee Related CN102573960B (zh) 2009-09-30 2010-09-29 用于药物递送装置的驱动机构

Country Status (10)

Country Link
US (1) US8939945B2 (enExample)
EP (1) EP2482887B1 (enExample)
JP (1) JP5722332B2 (enExample)
CN (1) CN102573960B (enExample)
AU (1) AU2010302982B2 (enExample)
BR (1) BR112012007209A2 (enExample)
CA (1) CA2773927A1 (enExample)
DK (1) DK2482887T3 (enExample)
IL (1) IL218835A (enExample)
WO (1) WO2011039232A1 (enExample)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8945063B2 (en) 2009-03-20 2015-02-03 Antares Pharma, Inc. Hazardous agent injection system
US9144648B2 (en) 2006-05-03 2015-09-29 Antares Pharma, Inc. Injector with adjustable dosing
US9180259B2 (en) 2005-01-24 2015-11-10 Antares Pharma, Inc. Prefilled syringe jet injector
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US9333309B2 (en) 2002-02-11 2016-05-10 Antares Pharma, Inc. Intradermal injector
US9364610B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Injection device with cammed ram assembly
US9393367B2 (en) 2013-03-12 2016-07-19 Antares Pharma, Inc. Prefilled syringes and kits thereof
US9446195B2 (en) 2011-07-15 2016-09-20 Antares Pharma, Inc. Injection device with cammed ram assembly
US9486583B2 (en) 2012-03-06 2016-11-08 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
US9561333B2 (en) 2008-08-05 2017-02-07 Antares Pharma, Inc. Multiple dosage injector

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8251947B2 (en) 2006-05-03 2012-08-28 Antares Pharma, Inc. Two-stage reconstituting injector
EP2990067B1 (en) 2008-03-10 2019-09-04 Antares Pharma, Inc. Injector safety device
EP4186545A1 (en) 2012-04-06 2023-05-31 Antares Pharma, Inc. Needle assisted jet injection administration of testosterone compositions
FI3659647T3 (fi) 2013-02-11 2024-03-28 Antares Pharma Inc Neula-avusteinen suihkuinjektiolaite, jolla on pienennetty liipaisinvoima
EP3572108A1 (en) 2013-03-11 2019-11-27 Antares Pharma, Inc. Dosage injector with pinion system
CN104307072A (zh) * 2014-10-29 2015-01-28 杭州普昂医疗科技有限公司 安全式胰岛素笔针
WO2021122221A1 (en) 2019-12-18 2021-06-24 Novo Nordisk A/S Injection device for delivering a liquid drug and a method of assembly

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659327A (en) * 1985-11-26 1987-04-21 Dentsply Research & Development Corp. Multiple dosage syringe
EP0338806A2 (en) * 1988-04-18 1989-10-25 Turner, Robert Charles Syringes
CN2375316Y (zh) * 1999-05-12 2000-04-26 中国药科大学 双腔多注射量程显微注射仪
EP1074273A1 (en) * 1999-08-06 2001-02-07 Becton Dickinson and Company Improved medication delivery pen
US20060247581A1 (en) * 2003-09-08 2006-11-02 Novo Nordisk A/S Threaded rod and nut assembly

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545147A (en) 1992-10-20 1996-08-13 Eli Lilly And Company Anti-backup improvement for hypodermic syringes
DE10237258B4 (de) 2002-08-14 2006-09-21 Tecpharma Licensing Ag Injektionsvorrichtung
DE102007026083A1 (de) * 2007-05-25 2008-11-27 Haselmeier S.A.R.L. Injektionsgerät

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659327A (en) * 1985-11-26 1987-04-21 Dentsply Research & Development Corp. Multiple dosage syringe
EP0338806A2 (en) * 1988-04-18 1989-10-25 Turner, Robert Charles Syringes
CN2375316Y (zh) * 1999-05-12 2000-04-26 中国药科大学 双腔多注射量程显微注射仪
EP1074273A1 (en) * 1999-08-06 2001-02-07 Becton Dickinson and Company Improved medication delivery pen
US20060247581A1 (en) * 2003-09-08 2006-11-02 Novo Nordisk A/S Threaded rod and nut assembly

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9333309B2 (en) 2002-02-11 2016-05-10 Antares Pharma, Inc. Intradermal injector
US9180259B2 (en) 2005-01-24 2015-11-10 Antares Pharma, Inc. Prefilled syringe jet injector
US9144648B2 (en) 2006-05-03 2015-09-29 Antares Pharma, Inc. Injector with adjustable dosing
US9561333B2 (en) 2008-08-05 2017-02-07 Antares Pharma, Inc. Multiple dosage injector
US8945063B2 (en) 2009-03-20 2015-02-03 Antares Pharma, Inc. Hazardous agent injection system
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US9446195B2 (en) 2011-07-15 2016-09-20 Antares Pharma, Inc. Injection device with cammed ram assembly
US9486583B2 (en) 2012-03-06 2016-11-08 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
US9364610B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Injection device with cammed ram assembly
US9364611B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US9393367B2 (en) 2013-03-12 2016-07-19 Antares Pharma, Inc. Prefilled syringes and kits thereof

Also Published As

Publication number Publication date
WO2011039232A1 (en) 2011-04-07
JP2013506464A (ja) 2013-02-28
CN102573960A (zh) 2012-07-11
CA2773927A1 (en) 2011-04-07
HK1169054A1 (en) 2013-01-18
EP2482887B1 (en) 2014-07-30
JP5722332B2 (ja) 2015-05-20
US20120296287A1 (en) 2012-11-22
DK2482887T3 (da) 2014-10-27
EP2482887A1 (en) 2012-08-08
BR112012007209A2 (pt) 2016-04-05
IL218835A0 (en) 2012-06-28
IL218835A (en) 2014-04-30
AU2010302982B2 (en) 2014-11-06
US8939945B2 (en) 2015-01-27
AU2010302982A1 (en) 2012-04-19

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20141210

Termination date: 20190929

CF01 Termination of patent right due to non-payment of annual fee