CN102553031A - Safety infusion set on basis of bubble point pressure principle - Google Patents

Safety infusion set on basis of bubble point pressure principle Download PDF

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Publication number
CN102553031A
CN102553031A CN2011102783623A CN201110278362A CN102553031A CN 102553031 A CN102553031 A CN 102553031A CN 2011102783623 A CN2011102783623 A CN 2011102783623A CN 201110278362 A CN201110278362 A CN 201110278362A CN 102553031 A CN102553031 A CN 102553031A
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dropping funnel
bubble point
point pressure
filtration medium
exhaustor
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李林风
陈志强
王铮
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Abstract

The invention relates to the technical field of medical instruments, in particular to a safety infusion set on the basis of the bubble point pressure principle. The technical scheme includes that a liquid medicine filter medium with the bubble point value ranging from 7.85 to 25kPa is selected according to the bubble point pressure principle, infusion of liquid medicine is stopped automatically according to the characteristics of the liquid medicine filter medium when the liquid medicine in the infusion set drips off, so that air can be prevented from entering an infusion tube and safety is guaranteed. Further, an exhaust tube extending to an inner cavity of a dropper is arranged in the dropper, a filter medium capable of exhausting air but not draining liquid is arranged at the extending end of the exhaust tube, so that automatic exhaust is realized significantly and safely and the high-efficiency and safe air separation effect is realized since the infusion set is combined with the bubble point pressure principle.

Description

Safe transfusion system based on the bubble point pressure principle
Technical field
The present invention relates to technical field of medical instruments, be specifically related to a kind of safe transfusion system based on the bubble point pressure principle.
Background technology
Existing transfusion device is preventing that the air admission blood vessel from causing malpractice and simple and direct stably the realization to have deficiency and risk aspect the infusion front exhaust.Prevent the problem of air admission blood vessel about the former, the method that hundreds of technical scheme comparisons concentrated area of having proposed is used float to stop up and stopped to infuse realizes, no matter these class methods or product all show complicated in manufacturing process, cost or the clinical use; Realize the problem of infusion front exhaust about the latter; At the dropping funnel shoulder chemical feed pipe is set as far back as the technical scheme by the dropping funnel of Chinese patent CN 88 2 02270 U medical plastic transfusion devices in 1988; Can be used as aerofluxus and regulate liquid level in the dropping funnel with regard to proposing with the mode of manual opening-closing; Be a kind of blank, various afterwards perforation is in order to all variations of blank for this reason of deflated various schemes on the dropping funnel wall, and one Chinese patent application 200810071550.7 automatic vent intravenous transfusion device for medical purpose technical schemes in 2008 then propose in dropping funnel, to install an end and stretch into dropping funnel inner chamber middle part; The other end covers the exhaustor of the air filtration film that not discharge opeing of aerofluxus is installed; 200920277618.7 1 kinds of automatic-exhaust transfusion devices of the similar Chinese patent of technical scheme or 200910238574.1 1 kinds of automatic-exhaust transfusion devices of Chinese invention patent application also propose consistent technical scheme therewith, and the advantage that they have jointly is to realize automatic vent to a certain extent, shortcoming then be can't be compatible international perforator and the product form of dropping funnel disjunctor; And still need close actuator in advance during bleeding; Open after the completion, close again during venipuncture etc., operate still numerous and diverse; Fail the real automatic vent bragged about realized; Especially outstanding technological deficiency is that its deflated conceptual design very easily causes the discharge duct thromboembolism, finally causes self-bleeding failure.For three similar techniques schemes such as above-mentioned one Chinese patent application 200810071550.7 grades; One of its shortcoming; The problem of the perforator that can't be compatible international and the product form of dropping funnel disjunctor; Chinese patent 200920270695.X has then done this preferably and has handled; Yet its shortcoming then is to carry out aerofluxus in the dropping funnel through the mode of manual opening-closing, on pattern, has the advance, and the technical scheme of the dropping funnel of practicality and above-mentioned 1988 Chinese patent CN 88 2 02270 U medical plastic transfusion devices is as good as.
Up to now; The application of filter medium on transfusion device for the traditional infusion device; Because of it uses the pursuit that upward existence is the bigger the better to flow; Its foaming point value trends towards zero and is ignored fully, and it is much uncertain that the careful mode that adopts float to stop up of some technical scheme realizes preventing that the air admission blood vessel from existing, thereby also be concerned about filter medium and the out of date drag relationship of flow of liquid; Attempt to utilize the resistance of filter medium to carry out the strick precaution of above-mentioned the former risk; So the mode of taking is the number of plies of stack filter medium, the risk of doing existence like this is: 1. the resistance of liquid is not had inevitable definitiveness, 2. objectively increased the resistance of filter medium but reduced the flow efficient of filter medium.The core feature of filter medium is not familiar with or is touched to this mode, i.e. the bubbling point characteristic of filter medium.
With one of the present invention program pattern with immediate in appearance be Chinese invention patent application 201010123045.X safe bubble-free infusion set; This technical scheme follows three similar techniques schemes such as above-mentioned one Chinese patent application 200810071550.7 grades in self-bleeding technical finesse; Clearly do not disclose the principle that it can prevent that blood from refluxing and call oneself with " safe bubble-free assembly " and " can prevent that blood refluxes when transfusion finishes " in the performance specification of the description of its application for a patent for invention (see 0006,0007 and 0008 section), but infer that from its statement and the general knowledge that combines clinical general knowledge or human body natural to possess blood pressure the technical staff in present technique field all knows will reach " can prevent that blood refluxes when transfusion finishes "; How many times no matter the pipeline liquid that then must guarantee transfusion device remain; All being in barotropic state, is that the interior liquid of transfusion device pipeline is in the infusion state all the time and keep a prerequisite of barotropic state, can confirm that thus its " safe bubble-free assembly " do not have the ability or the needs of barrier fluid or stop liquid infusion; The performance of said " can prevent that blood refluxes when transfusion finishes " is when the medicinal liquid infused but before changing transfusion; Through slowing down transfusion speed even reaching that trace transfusion realizes, therefore, the shortcoming of its technical scheme is also obvious; Promptly by infusion to as if one vital sign and can free active living person is arranged; When transfusion is dripped patient when empty in case habitually movable limbs and Body Position Change, when causing the height change of human vein point of puncture position, based on the transfusion device of gravity transfusion; Human vein puncture infusion point position uprises; Act on that the gravity of liquid diminishes relatively in the transfusion device pipeline, blood refluxes immediately, prevents that blood from refluxing not know where to begin; Human vein puncture infusion point position step-down; What act on liquid in the transfusion device pipeline becomes big to lower pulling force, and then the air vacuum suction that can form because of liquid is drop-down breaks through the pipeline that said multilamellar liquid medicine filtering membrane gets into transfusion device, is changing once more when infusing; Especially the nursing staff fully trust its performance and before changing transfusion once more to implement infusion failure to inspect have or not air, pernicious malpractice then very easily takes place.
The disclosed technical scheme of one Chinese patent application 200810148958.X for another example, its theme and description all clearly propose to use " blood return prevention filter " " can reach the effect of no bubble and blood return prevention " Instructions Page 2 of its application for a patent for invention (see the 1st section).Three so-called blood return prevention performances that similar patent application proposes as indicated above; Be under the effect of continuous positive pressure, could realize, say " flow velocity is more and more slower " as its description, its essence and above-mentioned trace transfusion are duplicate; Although in fact the disclosed scheme of 200810148958.X does not fully disclose the mechanism of action of its blood return prevention; But by its blood return prevention performance and reach the then deducibility of blood return prevention performance conditions needed, its description is carried " gas can not pass through, and liquid stream promptly stops to flow; liquid level can not descend again "; Its essence should be that a kind of trace that stops that under immobilized relatively state, being similar to flows, i.e. trace transfusion, otherwise blood return prevention is not known where to begin; Therefore the same with above-mentioned three similar techniques schemes; This approximate trace that stops to flow finally and can under the nursing staff neglect the situation of long or Body Position Change of time, cause that bubble gets into conduit, again the nursing staff trust its performance or situation about not discovering under continue transfusion and lead to serious accident, the risk that its risk and above-mentioned three similar techniques schemes are implied is exactly the same.Above-mentioned this deduction can draw sure conclusion with the simulation test of reality, the method for using that also can from the description of its patent application, propose---obtain evidence in the statement of " when changing the bottle dosing, close actuator earlier then change a bottle dosing ".Those skilled in the art is all clear; The sole purpose of closing actuator is to close down the transfusion device path with the auxiliary physical means of external force, stops to flow " liquid stream promptly stops to flow; liquid level can not descend again " that the 200810148958.X patent application is mentioned with the liquid in the forced path; Do not stop if be not in fact that liquid stream is approximate, but stop really, that need not to close actuator.Those skilled in the art with clinical general knowledge are clear, and transfusion device can move with nursing staff's hands when changing medicine bottle, and the height that its effect is similar to the transfusion outpatient body odour changes; This variation can cause the change of action of gravity size, thereby causes the variation of infusion flow rate, if flow velocity increases suddenly; Then change the state of its " more and more slower ", thereby break the illusion of its what is called " liquid stream promptly stops to flow ", cause the air admission conduit in moment; So need close actuator during the replacing medicine bottle of this scheme; That kind just can be avoided when changing medicine bottle, causing the air admission conduit, but key is, the change of position height not merely just appears at changes medicine bottle in that under situation; Medicine bottle drip empty to the time length of changing new drug neither be at every turn all; These factors all may be brought serious accident, be to make infusion flow rate slow down and trend towards micro-infusion in essence and the root of these risks all is this scheme " blood return prevention filter ", and fict transfusion stop.
Summary of the invention
The object of the invention provides a kind of shortcoming, risk of relating in the above-mentioned background technology can comprehensively avoided; Can realize simultaneously the transfusion device manufacturing approach of safe infusion again, and further realize on this basis need not manual intervention really the automatic vent performance, based on the safe transfusion system of bubble point pressure principle.
The object of the invention is achieved in that respectively
Scheme one
A kind of safe transfusion system based on the bubble point pressure principle; Transfusion device comprises perforator 1, air inlet part 13, dropping funnel 2, crosses medicinal liquid filter medium 21, pipeline 3 and actuator 4; Said medical filtration medium 21 is installed on the transfusion device medicinal liquid path, the bubble point pressure of the medical filtration medium 21 of transfusion device greater than 7.85kPa less than 25.00kPa.
Bubbling point, promptly Bubble Point claims the bubble point again; Be to promote air through the required pressure of the filter medium that is full of by liquid, when pressure constantly increase and reach overcome on the filter medium than macropore in during surface tension of liquid, then liquid flows out from the hole; Bubble has just come out, and the force value when first bubble comes out is a bubbling point, and bubble point pressure promptly refers to reach the pressure of bubbling point numerical value; In other words, just can filter medium intercept the bubble point pressure marginal value of air.
Liquid injects after the dropping funnel 2 and pipeline 3 of transfusion device; 21 in medical filtration medium is soaked into by liquid and is full of; Empty when fluid drips, under action of gravity, the liquid of medical filtration medium below 21 forms a downward pulling force to medical filtration medium 21; Promptly be equivalent to the pressure that medical filtration medium 21 bears a vertical direction, this pressure can directly act on medical filtration medium 21 and built-in liquid thereof with the direction of vertical medical filtration medium 21.Because the pipeline length of GB transfusion device is fixed; Can to medical filtration medium 21 form pressure pipeline 3 length, be that liquid-column height in the pipeline 3 generally is fixed; If its formed pressure is XkPa; Usually, because the specification of transfusion device is fixed, so this pressure also is fixed.And all there is bubbling point in any filter medium, and difference is big or little, and bubble point pressure is during less than XkPa; Air then can overcome the surface tension of liquid of medical filtration medium 21 easily; Liquid flows out from the micropore of medical filtration medium 21, causes air to follow liquid thereupon and gets into the pipeline 3 of medical filtration medium below 21, can't reach the effect that intercepts air; Otherwise if during greater than XkPa; Then this pressure can't make air then can overcome the surface tension of liquid of medical filtration medium 21, medicinal liquid filter medium 21 is reached intercept air admission infusion pipeline 3, avoids the safe effect of intravasation.
The present invention confirms that the bubble point pressure of said medical filtration medium 21 is between the 7.85kPa to 25.00kPa, then is to consider that human body exists the actual transfusion height of venous pressure and transfusion device can adjust the terminal height of transfusion device according to different occasions, and then the actual meeting of relative altitude of itself and medical filtration medium 21 is less than XkPa; For example accept transfusion person and adopt seat when transfusion; Reach the purpose that intercepts air but to the requirement of bubble point pressure less than XkPa, lower limit is that 7.85kPa get final product, equals XkPa basically in the requirement of adopting clinostatism to infuse then to bubble point pressure; A large amount of simulation experiments, clinical trial and calculating data all show; According to the specification of the catheter length and the caliber of GB transfusion device, bubble point pressure is that 16.5kPa is best, and the setting of higher limit 25.00kPa then is to consider to confirm from the angle incision of safety coefficient; Under extreme case; As the first aid occasion when losing blood greatly, bigger bubble point pressure setting can be guaranteed safety, avoids performance failure.
Need to prove that above-mentioned bubbling point numerical value is meant the actual numerical value scope that medical filtration medium 21 is had when being installed in transfusion device, these scopes are safe; Yet consider that high height above sea level and low height above sea level are to difference that pressure influence caused; The transfusion device manufacturing should have universality, and therefore as the universal type of transfusion device, the bubble point pressure that the present invention advocates is 16.5kPa~25.00kPa; Certainly; Medical filtration medium 21 can be installed on any point of transfusion device medicinal liquid path, and its installation site is the closer to patient end, and promptly transfusion device is terminal; It is just low more that it reaches the required bubble point value of the performance that intercepts air admission pipeline 3; Even therefore ignore the changing factor of transfusion position mentioned above, the bubble point lower limit 7.85kPa that the present invention proposes also is safe, and the installation site that is applied bubble point value and medical filtration medium 21 must rigid associated in correspondence.
Wherein, Said medical filtration medium 21 is hollow bag shape diaphragm or column or hollow columns of at least one tunic sheet or diaphragm-operated combination of multilamellar or top closure; In the present invention; The form of medical filtration medium 21 is not fixed, as long as reach bubbling point numerical value of the present invention, the variation of its form submits to the position of installation, pattern and technology.
As preferably, said medical filtration medium 21 is installed on the bottom of dropping funnel 2, and is fixing or directly be locked in dropping funnel 2 bottoms by support 25.Although being installed in the optional position of transfusion device medicinal liquid path, medical filtration medium 21 all can realize the object of the invention; But the simplest and the easiest angle of aerofluxus from structure; The bottom that is installed on dropping funnel 2 is a preferred version; It is assemblied in dropping funnel 2 bottoms after can and fixing by support 25 sealing the margins, also can directly adopt modes such as including but not limited to welding, heat-sealing, adhesion to be locked in dropping funnel 2 bottoms.
As preferably; The minimum point that the position of the liquid outlet 22 of said dropping funnel 2 is higher than the dropping funnel 2 inner chamber useful spaces is 1mm at least; Because medical filtration medium 21 has the characteristic that intercepts air after being soaked into by medicinal liquid; The air in the gap between liquid outlet 22 and the medical filtration medium 21 can't be discharged to the epimere space of dropping funnel 2, and such being provided with helps the air in the delivery space, has the liquid waste that causes because of bubble during with the minimizing aerofluxus.
Being communicated with for said dropping funnel 2 and conduit 3 in this programme; Be to distinguish to some extent according to transfusion device material of selecting for use when different occasions are used; And take dual mode to realize respectively: when institute's materials used is easy to direct bonding connection; As preferably, said dropping funnel 2 is modes that pipeline 3 links insert link 23 inner chambers of dropping funnel 2 with the mode of communicating of pipeline 3; When institute's materials used is difficult to direct bonding connection; As preferably; The inner chamber of the link 23 of said dropping funnel 2 is inlaid with an inner core 24; Inner core 24 is hollow pipes of a both ends open, and said dropping funnel 2 is that pipeline 3 one ends insert in the inner core 24 of link 23 inner chambers that are embedded in dropping funnel 2 with the mode of communicating of pipeline 3.Two kinds of connected modes all help to eliminate the forward dead angle of fluid path and avoid keeping bubble at the place, dead angle, and the purpose that is designed to be higher than the dropping funnel intracavity bottom with the liquid outlet 22 of dropping funnel 2 is consistent with effect.
The realization principle of this programme is to utilize medical filtration medium 21 to have the characteristic of bubbling point after moistening by medicinal liquid; Make medicine liquid droplet empty, when medical filtration medium 21 is exposed to air; Air is limited by the bubble point pressure of medical filtration medium 21; Can't pass through medical filtration medium 21 and form sealing infusion pipeline 3; Force medicinal liquid to stay on the horizontal plane of medical filtration medium 21, in the transfusion device path of no air admission medical filtration medium below 21, thus the safe effect of realization separate air.
The present invention is based on the safe infusion that the bubble point pressure principle is set forth; Have advantages such as safety and stability, definite effect is inevitable, pattern is succinct, manufacturing process is simple; To improving transfusion safety, avoid the unexpected intravasation of air, reduce nursing staff's working risk significance.
Scheme two
A kind of safe transfusion system based on the bubble point pressure principle; Transfusion device comprises bottle plug puncture unit 1, dropping funnel 2, medical filtration medium 21, exhaustor 14, pipeline 3 and actuator 4; Medical filtration medium 21 by support 25 fixing or directly sealing be installed in dropping funnel 2 bottoms, and make itself and the marginal fit of dropping funnel 2 bottoms, wherein exhaustor 14 1 ends stretch in the middle part of dropping funnel 2 inner chambers; Exhaustor 14 exhaust passages are covered with the air filtration media 141 of not discharge opeing of aerofluxus; It is characterized in that less than 25.00kPa, said air filtration media 141 is installed in the end that exhaustor 14 stretches into dropping funnel 2 inner chambers to the bubble point pressure of said medical filtration medium 21 greater than 7.85kPa.
Wherein, flow is less than 1.0mL/min less than 1.5kPa pressure reduction the time for said medical filtration medium 21, and said air filtration media 141 is installed in the end 144 that exhaustor 14 stretches into dropping funnel 2 inner chambers one end.
Because the bleeding of transfusion device is actually a process that becomes transfusion device inner chamber air displacement liquid; The transfusion device of conventional version; Extruding dropping funnel 2 is in the bleeding of implementing in the draws fluid dropping funnel 2 to fill, and key is to go out the air extrusion in the infusion unit titrimeter 2, begins to get into dropping funnel 2 to attract liquid; Thereby under action of gravity with the air of heavy liquid extrusion ratio heavy and light; Make liquid be full of pipeline 3 and the completion aerofluxus, in other words, the prerequisite that liquid can get into dropping funnel 2 is an air-out.In the present technique scheme, transfusion device is equipped with an exhaustor 14 that stretches into dropping funnel 2 inner chambers middle part and band air filtration media 141, and exhaustor 14 is hollow pipes of an outer wall sealing; Its inner chamber is communicated with dropping funnel lid 12 or sidewall and connects with the external world, and this is set to air in the dropping funnel 2 and discharges a passage is provided, when the puncture bottle stopper and when hanging up infusion bottle; Under action of gravity; Liquid can get into dropping funnel 2 along the feed pathway of bottle plug puncture unit 1, and the proportion of liquid is greater than air, so liquid can push air and from dropping funnel 2, discharges to the external world; Want air-out then to have only two passages in liquid inlet of exhaustor 14 and conduit 3 to select this moment for dropping funnel 2.And wherein, flow is less than 1.0mL/min less than 1.5kPa pressure reduction the time for said medical filtration medium 21, and this pressure reduction is about as much as the pressure of 150mm water column; Because medical filtration medium 21 just has the flow of 1.0mL/min under the pressure that is about as much as the 150mm water column, in other words, get into the initial of dropping funnel 2 at liquid; The path of exhaustor 14 is open, and the pressure reduction that acts on medical filtration medium 21 has only the head of liquid of having accumulated liquid level in the dropping funnel 2, and dropping funnel 2 is generally less than the 100mm height; So because insufficient pressure; Liquid can't be crossed medical filtration medium 21 immediately in a large number, is actually to have postponed liquid through liquid outlet 22 entering conduits 3, and liquid is postponed in dropping funnel 2; Simultaneously also shutoff one of them of 2 two air discharging channel of dropping funnel, then the air in the dropping funnel 2 can only be discharged from exhaustor 14.Simultaneously since the design discharge of transfusion device generally greater than 50mL to 100mL/min; And pipeline is more up to 1000mL/min; The amount that liquid gets into dropping funnel 2 is big; Flow out and then to be postponed, cause liquid fast in the accumulation of dropping funnel 2 inner chambers, accumulation is raised liquid levels in the dropping funnel 2 and is also pushed air conversely and continue to discharge via exhaustor 14.The interaction of above-mentioned factor is accumulated the liquid in the dropping funnel 2 rapidly and is raised liquid level, and during air filtration media 141 in submergence exhaustor 14, this air filtration media 141 is not discharge opeings of aerofluxus; It has then sealed the passing away of air in the dropping funnel 2 submergence, stops thereby making in the dropping funnel 2 accumulation of liquid levels raise trend, reaches the required needs of filling with about 1/2 dropping funnel 2 of clinical practice; Accomplish the liquid fill of dropping funnel 2, and simultaneously, because air filtration media 141 is by submergence; Thereby shutoff exhaustor 14 makes dropping funnel 2 revert to a hermetic container, and bottle plug puncture unit 1 is anastomosing with infusion bottle; So shutoff exhaustor 14 back dropping funnels 2; Be connected the passage of " infusion bottle-bottle plug puncture unit 1-dropping funnel 2 ", behind this channel connection, in fact the liquid-column height that acts on medical filtration medium 21 is brought up to the liquid level in the infusion bottle immediately; Be liquid level head and shoulders above medical filtration medium 21 keep the height of minute water through the 150mm water column of amount; Pressure down-off at this fluid column can progressively increase rapidly, and it is descending that liquid is broken through 21 beginnings of medical filtration medium, until accomplishing aerofluxus.Thus, realize only need inserting action of bottle, need not to push dropping funnel 2, can implement and accomplish deflated performance automatically according to the transfusion device of this programme design.
In the present technique scheme; Said exhaustor 14 1 ends stretch into the about medium position of dropping funnel 2 inner chambers; The said air filtration media 141 that is covered with not discharge opeing of aerofluxus is installed in the end that exhaustor 14 stretches into dropping funnel 2 inner chambers part; As preferably, air filtration media 141 is installed in exhaustor 14 and stretches into the end 144 in the dropping funnel 2.The position design of above-mentioned air filtration media 141; With the scheme that is installed in air filtration media 141 at the end of exhaustor 14 outside dropping funnel 2; Be distinct; Discloseder other technologies schemes all are provided with air filtration media 141 outside dropping funnel 2 based on the easy instinct trend of production technology; But that is the failure scheme that lacks clinical experience, and the present invention program is to prevent liquid embolic in use to occur as the exhaustor 14 of air discharging channel at the beneficial effect of this design, thereby avoids the automatic vent performance failure.Above-mentioned one Chinese patent application 200810071550.7 all is provided with exhaustor 14 1 ends and stretches into dropping funnel 2 inner chambers middle part, and the other end that the air filtration film is covered in exhaustor 14 is set in three similar techniques schemes of representative; Be that the air filtration film is installed in outside dropping funnel 2 inner chambers, the difference of itself and present technique scheme is, when medicinal liquid fills dropping funnel 2; Need fill with dropping funnel 2 bottoms; And then trace back along exhaustor 14 inner chambers and to fill with whole exhaustor 14, arrive the air filtration film that is positioned at exhaustor 14 other ends, just by the shutoff of air filtration film; Stop filled process to dropping funnel 2; In these technical schemes, owing to get into the liquid of dropping funnel 2 and need trace back,, very easily after getting into exhaustor 14 inner chambers, can't discharge and cause thromboembolism simultaneously because liquid has the molecular surface adsorption to the inner chamber that is full of whole exhaustor 14; Shutoff the exhaust passage of exhaustor 14; Aerofluxus once more when changing new medicine bottle causes self-bleeding inefficacy, and these failure phenomenons are especially typical and common when use is more heavy-gravity such as medicinal liquids such as Radix Salviae Miltiorrhizae Injection, intravenous injection gamma globulin and fat milks.Technical scheme of the present invention; Utilize the ingenious end 144 of putting filter medium 141 in exhaustor 14 of technologic improvement; The thromboembolism that the inner chamber of then having avoided liquid to get into exhaustor 14 causes; Efficiently solve the defective in the prior art scheme, also increased the safety of transfusion device itself simultaneously, avoid in making, packing and transportation, stabbing air filtration media 141 and cause non-expection to pollute.
In the present technique scheme; Liquid fill arrives the end 144 of exhaustor 14; Be that shutoff is positioned at terminal 144 air filtration media 141, stop aerofluxus, because air filtration media 141 has the characteristic of not discharge opeing of aerofluxus to dropping funnel 2 inner chambers; So whole infusion process no liquid gets into the bore passages of exhaustor 14, the thromboembolism that does not exist liquid adsorption to cause causes the aerofluxus Problem of Failure.To be technical scheme of the present invention be different from above-mentioned one Chinese patent application 200810071550.7 in essence in design is one of key point of three similar techniques schemes of representative for this.
In the present technique scheme, said exhaustor 14 is hollow pipes of outer wall sealing, and is to be constituted or be formed by connecting the multistage hollow pipe one section hollow pipe.This is two kinds of designs that realize exhaustor 14 equal effects in this programme; Preferred as the mold convenience, can directly constitute by one section hollow pipe, and preferred as the convenience of processing; Then can be formed by connecting, in this programme, all can reach equal performance at least two sections hollow pipes.
In the present technique scheme, an end of said exhaustor 14 is communicated with last capping or the sidewall of dropping funnel lid 12 and connects with the external world, and with air exit 142 places of external world's perforation be equipped with one can open or close air exit block 143.Air exit 142 occurs with opening-wide state, and the performance that can't influence the present technique scheme realizes, yet answers the design angle of the various different occasions of As soon as possible Promising Policy from range of application; Air exit 142 is set to and can opens or close, then under egregious cases, when wound massive hemorrhage patient is implemented first aid; May implement big flow transfusion, or remove venoclysis needle, change the large size entry needle; This moment since dropping funnel 2 be two-way via the unlatching of exhaustor 14 to the external world, the amount that liquid injects is during greater than the amount of infusion, but dropping funnel 2 outside aerofluxuss or keep balance basically; Simultaneously also because liquids and gases all belong to fluid; And when implementing fast infusion, liquids and gases then occurring injects in the dropping funnel 2 simultaneously, causes the problem of infusion underfed and 2 skies of dropping funnel; And for being three similar techniques schemes of representative with above-mentioned one Chinese patent application 200810071550.7,2 skies of dropping funnel then can cause the accident in the macro-mixing bubble intravasation.Though for technical scheme of the present invention; Owing to the characteristic of medical filtration medium 21 does not have this risk; But when some extremity such as rescue, need under the situation of heavy dose of transfusion fast; Because air injects dropping funnels 2 and causes the risk of infusion underfed to exist really from air exit 142, therefore, technical scheme of the present invention be equipped with at air exit 142 places one can open or close air exit block 143; Aerofluxus can be closed air exit 142 after accomplishing, and under extreme case, can effectively stop risk.In addition; Air exit 142 is provided with the block 143 that can open or close air exit; Use in the time of also can satisfying pressure transfusion; The pressure of a lot of pressure transfusions reaches 0.3MPa, and this is not 141 pressure that can load of air filtration media of said not discharge opeing of aerofluxus, and the block 143 of closed air exit can be satisfied the demand.
When transfusion device drips sky, do not reach when changing transfusion, dropping funnel 2 can progressively drip sky.Owing to be installed on the medical filtration medium 21 of the bottom of dropping funnel 2; Be that a kind of bubbling point is the filter medium of 7.85kPa to 25.00kPa, have the performance that intercepts air, thus when the medicine liquid droplet in the dropping funnel 2 empty to when medical filtration medium 21 is exposed to air; Air is limited by the bubble point pressure of medical filtration medium 21 then; Can't pass through medical filtration medium 21 and form sealing, force medicinal liquid to stay on the horizontal plane of medical filtration medium 21, in the transfusion device path of no air admission medical filtration medium below 21 infusion pipeline 3; Reach the safe effect of separate air, this is consistent with scheme one on its mode, principle and effect.
Continue infusion once more and change transfusion, also only need insert bottle and get final product, the performance of its method for using and automatic vent performance and obstruct air is also consistent when using first, need not manual intervention.
The present technique scheme realizes that the object of the invention principle is such: utilization is provided with one and stretches into dropping funnel 2 inner chambers and the air filtration media 141 ingenious exhaustors 14 that are installed in inserting end terminal 144; Discharging for the air of dropping funnel 2 provides passage; The inner chamber that stops liquid to invade exhaustor 14 simultaneously causes thromboembolism; Utilize medical filtration medium 21 after moistening, have bubbling point and can postpone the characteristic that medicinal liquid passes through again by medicinal liquid; Under factor combineds effect such as gravity, exhaustor 14, bubbling point and delay medicinal liquid pass through; Can fill dropping funnel automatically and discharge unnecessary air after making transfusion device insert bottle earlier, and make transfusion device when medicine liquid droplet sky, medical filtration medium 21 are exposed to air, air is limited by the bubble point pressure of medical filtration medium 21; Can't pass through medical filtration medium 21 and form sealing infusion pipeline 3; Force medicinal liquid to stay on the horizontal plane of medical filtration medium 21, in the transfusion device path of no air admission medical filtration medium below 21, thereby realize that medicinal liquid fills automatically, automatic vent, separate air and stop automatically infusing etc. multiple-effect can simple and direct and safe effect.
The present technique scheme is owing to adopt above-mentioned principle manufacturing; Compare with three similar techniques schemes of said 200810071550.77 grades of background technology; Realized the said function that it is alleged, but the air filtration media 141 of exhaustor 14 the position is set, solved the problem of exhaustor 14 passage thromboembolisms; Stop self-bleeding failure risk, really realized automatic vent; Compare with 201010123045.X; Can overcome the serious accident risk that it is hidden; Realize that patient no matter is in the security performance which kind of position can guarantee stably that all air can not intravasation, and make the nursing staff have ready conditions changing transfusion by easy stages, avoid mistake.According to the present technique scheme, the application operating of transfusion device to need only really to have realized one to insert the bottle action, can need not human intervention and automatic vent intactly; And repeatedly changing under the transfusion state; Performance is all kept unanimity, and has further improved the transfusion safety on this basis, avoids the unexpected intravasation of air; Save a large amount of infusion time; The working risk that reduces the nursing staff with reduce nursing staff's labor intensity, properties of product safety and stability, advantage such as definite effect is inevitable, pattern is succinct, manufacturing process is simple have remarkable meaning to improving whole injection quality.
Description of drawings
Fig. 1 is the transfusion device structural representation of embodiment 1 among the present invention program one.
Fig. 2 is the transfusion device structural representation of embodiment 2 among the present invention program one.
Fig. 3 is a transfusion device structural representation among the present invention program two.
The specific embodiment
Manufacturing approach of the present invention is done further with preferred embodiment below in conjunction with accompanying drawing and to be specified.
Scheme one:
In this programme, according to principle of the present invention, preferred 2 concrete embodiment of transfusion device are elaborated.
Embodiment 1:
Fig. 1 is based on the typical construction sketch map of the safe transfusion system of bubble point pressure principle.As shown in Figure 1; Transfusion device comprises perforator 1, air inlet part 13, dropping funnel 2, crosses medicinal liquid filter medium 21, pipeline 3 and actuator 4; Said medical filtration medium 21 is installed on the bottom of dropping funnel 2; Fixing and be locked in dropping funnel 2 bottoms by support 25, the bubble point pressure of the medical filtration medium 21 of transfusion device greater than 7.85kPa less than 25.00kPa.
As shown in Figure 1, the minimum point that the position of the liquid outlet 22 of said dropping funnel 2 is higher than the dropping funnel 2 inner chamber useful spaces is 1mm at least, and said dropping funnel 2 is inner chambers that pipeline 3 one ends insert the link 23 of dropping funnel 2 with the mode of communicating of said pipeline 3.
When working,, transfusion can implement infusion after being ready to complete according to the transfusion device of present embodiment 1.Empty at the infusion bottle medicine liquid droplet; When medical filtration medium 21 is exposed to air; Air is limited by the bubble point pressure of medical filtration medium 21, can't pass through medical filtration medium 21 and forms the sealing to infusion pipeline 3, forces medicinal liquid to stay on the horizontal plane of medical filtration medium 21; Realize stopping automatically of infusion, bring the risk of input air thereby separate air can not get into pipeline 3.
After changing transfusion, because medical filtration medium 21 has sealed the pipeline that comprises pipeline 3 below it, full of liquid in these passages; Add the existence that human vein is pressed, when therefore pushing dropping funnel 2 discharge dropping funnels 2 inner chamber air once more, need not to close actuator 4; Extruding dropping funnel 2; Air promptly can get in the infusion bottle, and the extruding of the dropping funnel 2 that liquid also can be everywhere fills liquid and gets into dropping funnel 2 inner chambers, makes liquid level approximately be in 1/2 dropping funnel, 2 height and can continue infusion.Drip sky if once more liquid in infusion bottle takes place; Transfusion device can realize automatically that still infusion stops and separate air; The nursing staff need not to worry because of the carelessness management or does not in time change the risk that bottle causes air admission conduit 3 or blood vessel; Can handle by easy stages, avoid mistake, improve the safety of doctor and patient.
Embodiment 2:
Fig. 2 is based on the sketch map of other a kind of configuration of the safe transfusion system of bubble point pressure principle, adopts this configurational energy to realize the performance equal with embodiment 1, also has the advantage of widening the special applications category simultaneously.
As shown in Figure 2; Transfusion device is made up of the assembly that comprises perforator 1, air inlet part 13, dropping funnel 2, inner core 24, medical filtration medium 21, pipeline 3 and actuator 4; Said medical filtration medium 21 direct sealing are installed on the bottom of dropping funnel 2, the bubble point pressure of the medical filtration medium 21 of transfusion device greater than 7.85kPa less than 25.00kPa.
As shown in Figure 2, the minimum point that the position of the liquid outlet 22 of dropping funnel 2 is higher than the dropping funnel 2 inner chamber useful spaces is 1mm at least.The inner chamber of the link 23 of dropping funnel 2 is inlaid with an inner core 24, and inner core 24 is hollow pipes of a both ends open, and dropping funnel 2 is inner cores 24 that pipeline 3 one ends insert link 23 inner chambers that are embedded in dropping funnel 2 with the mode of communicating of pipeline 3.
Structurally; According to the technical scheme of present embodiment, to compare with embodiment 1, its difference one of which is in link 23 inner chambers of dropping funnel 2; Increased an inner core 24; This inner core 24 is hollow pipes of both ends open, its two be dropping funnel 2 and pipeline 3 mode of communicating, in the present embodiment be: said pipeline 3 one ends insert in the inner core 24 of link 23 inner chambers that are embedded in dropping funnel 2 realizing and are communicated with.
In actual clinical; Because the difference of medicine can cause the absorption of transfusion device to effective ingredient, for example paclitaxel proposes the specific (special) requirements of material to transfusion device in such cases clinical meeting; And be not that simple use PVC can satisfy, possibly also relate to materials such as PP, TPE.The transfusion device of present embodiment; Is on all four in when work with embodiment 1, and its beneficial effect is, present embodiment needs to use some suitable material in the occasion of some special requirement; When these materials that use are difficult to direct bonding connection; Can adjust the coupling of the material realization storeroom of inner core 24 according to the material different needs, when can effectively satisfy the special material application, also reach 1 on all four performance with embodiment.
Certainly, in the technical scheme of present embodiment, medical filtration medium 21 can directly be locked in the bottom of dropping funnel 2; Mode that also can be described in embodiment 1 is locked in the bottom of dropping funnel 2 by support 25, because present embodiment uses the inner core 24 of link 23 inner chambers that are embedded in dropping funnel 2; And mutually exclusive, come from the principle of work simplification preferred, present embodiment on material fit if can support; Should tend to directly be locked in dropping funnel 2 bottoms, make link to reduce, but the principle of its foundation; And the impact of performance of being reached, be on all four.
Scheme two:
In this programme, be elaborated with specific embodiment.
Fig. 3 is the typical construction sketch map of this programme based on the safe transfusion system of bubble point pressure principle.As shown in Figure 3; Transfusion device is made up of the assembly that comprises perforator 1, dropping funnel 2, medical filtration medium 21, exhaustor 14, pipeline 3 and actuator 4; Medical filtration medium 21 is fixedly mounted on dropping funnel 2 bottoms by support 25; And make the marginal fit of itself and dropping funnel 2 bottoms, and wherein exhaustor 14 1 ends stretch into dropping funnel 2 inner chambers middle part, and the end 144 of exhaustor 14 inserting ends covers the air filtration media 141 that not discharge opeing of aerofluxus is installed; The bubble point pressure of said medical filtration medium 21 greater than 7.85kPa less than 25.00kPa, and less than 1.5kPa pressure reduction the time flow less than 1.0mL/min.
As shown in Figure 3; Said exhaustor 14 is hollow pipes of an outer wall sealing; It is one section or is formed by connecting the multistage hollow pipe; One end of exhaustor 14 is communicated with last capping or the sidewall of dropping funnel lid 12 and connects with the external world, air exit 142 places of said exhaustor 14 and extraneous perforation be equipped with one can open or close air exit block 143.
Transfusion device through said method is made need not during work to close actuator 4, and blocking a shot should stay open in 143 o'clock; After inserting bottle plug puncture unit 1 and hanging up infusion bottle; Because the passage that exhaustor 14 provides gas to discharge, and the proportion of liquid is greater than gas, under action of gravity; The automatic dropping funnel 2 that gets into of liquid meeting fills, and the gas in the dropping funnel 2 then gets into, passes air filtration media 141 by the air exit 142 discharge external worlds through the end 144 of exhaustor 14.
When liquid arrived medical filtration medium 21, flow was less than 1.0mL/min less than 1.5kPa pressure reduction the time owing to medical filtration medium 21, and this pressure reduction is about as much as the pressure of 150mm water column; Because this characteristic liquid is postponed and accumulation in dropping funnel 2; Therefore under action of gravity, liquid continuous entering dropping funnel 2 inner chambers and extruding air are discharged from exhaustor 14, thereby until submergence air filtration media 141 shutoff exhaustors 14; And stop filling automatically to dropping funnel; And dropping funnel 2 upwards be communicated with infusion bottle and become one, cause the pressure reduction that acts on medical filtration medium 21 and increase suddenly, overcome medical filtration medium 21 less than 1.5kPa pressure reduction the time flow less than the characteristic of 1.0mL/min; Flow is progressively increased rapidly; It is descending that start liquid breaks through 21 beginnings of medical filtration medium in a large number, and the air that drives in the pipeline 3 is discharged from transfusion device is terminal, accomplishes aerofluxus automatically.So far; Transfusion device in this programme only need be accomplished one and insert after the operational motion of hanging up the bottle back; Need not manual compression dropping funnel 2, need not to close in advance actuator 4 and open actuator 4 afterwards, can accomplish automatically the aerofluxus of transfusion device is prepared; Overall process is accomplished without any letup, and efficient, simple and easy, result must.
When infusion uses; When taking place, negligence of management make the infusion bottle medicine liquid droplet empty; Liquid in the dropping funnel 2 reduces until walking sky gradually, and when medical filtration medium 21 was exposed to air, air was limited by the bubble point pressure of medical filtration medium 21; Can't pass through medical filtration medium 21 and form sealing infusion pipeline 3; Force medicinal liquid to stay in medical filtration medium 21 places, realize stopping automatically of infusion, bring again the risk of deflated trouble or input air thereby separate air can not get into pipeline 3.
After connecing the transfusion that renews, according to the transfusion device of this programme once more automatic vent, fill dropping funnel 2 and arrive and be fit to liquid level, until recovering transfusion again automatically; Connect the front and back that renew transfusion, all need not to close the operation of actuator 4 and extruding dropping funnel 2, the filled automatically liquid entering of transfusion device dropping funnel 2 makes liquid level approximately be in 1/2 dropping funnel, 2 height can recover to continue infusion; If take place to drip empty once more; Transfusion device can realize automatically once more that still infusion stops and separate air, and the nursing staff need not to worry and causes the risk of air admission pipeline 3 even intravasation because of the carelessness management, can handle by easy stages; Avoid mistake, effectively improve the safety of doctor and patient.
Although the above-mentioned two kinds of technical schemes of the present invention all are to describe with reference to specific embodiment, this description does not also mean that the present invention is constituted restriction.With reference to description of the invention, other variations of the disclosed embodiments are for example according to principle of the present invention; With the pattern of medical filtration medium 21 with the independent filter of band exhausting window; Be installed in the variation on the pipeline 3 of dropping funnel below 2, or, exhaustor 14 changed position of installing or the quantity that increases exhaustor 14 etc. for example according to principle of the present invention; These variations can expect all that to those skilled in the art this variation should belong in the affiliated claim institute restricted portion.

Claims (13)

1. safe transfusion system based on the bubble point pressure principle; Transfusion device comprises bottle plug puncture unit (1), air inlet part (13), dropping funnel (2), medical filtration medium (21), exhaustor (14), pipeline (3) and actuator (4); Said medical filtration medium (21) is installed on the transfusion device medicinal liquid path; It is characterized in that, the bubble point pressure of said medical filtration medium (21) greater than 7.85kPa less than 25.00kPa.
2. according to the said safe transfusion system of claim 1, it is characterized in that said medical filtration medium (21) is hollow bag shape diaphragm or the column or the hollow column of at least one tunic sheet or diaphragm-operated combination of multilamellar or top closure based on the bubble point pressure principle.
3. according to the said safe transfusion system of claim 1 based on the bubble point pressure principle; Said medical filtration medium (21) is installed on the transfusion device medicinal liquid path; It is characterized in that; Said medical filtration medium (21) is installed on the bottom of dropping funnel (2), fixes or directly be locked in dropping funnel (2) bottom by support (25).
4. according to the said safe transfusion system of claim 1, it is characterized in that the minimum point that the position of the liquid outlet (22) of said dropping funnel (2) is higher than dropping funnel (2) the inner chamber useful space is 1mm at least based on the bubble point pressure principle.
5. according to the said safe transfusion system of claim 1, it is characterized in that said dropping funnel (2) is the inner chamber that pipeline (3) one ends insert the link (23) of dropping funnel (2) with the mode of communicating of said pipeline (3) based on the bubble point pressure principle.
6. according to the said safe transfusion system based on the bubble point pressure principle of claim 1~5, it is characterized in that the inner chamber of the link (23) of said dropping funnel (2) is inlaid with an inner core (24), inner core (24) is the hollow pipe of a both ends open.
7. according to the said safe transfusion system of claim 6, it is characterized in that said dropping funnel (2) is the inner core (24) that pipeline (3) one ends insert link (23) inner chamber that is embedded in dropping funnel (2) with the mode of communicating of said pipeline (3) based on the bubble point pressure principle.
8. safe transfusion system based on the bubble point pressure principle; Transfusion device comprises bottle plug puncture unit (1), dropping funnel (2), medical filtration medium (21), exhaustor (14), pipeline (3) and actuator (4); Medical filtration medium (21) is installed in dropping funnel (2) bottom by the fixing or direct sealing of support (25); And make the marginal fit of itself and dropping funnel (2) bottom; Wherein exhaustor (14) one ends stretch into dropping funnel (2) inner chamber middle part, and the exhaust passage of exhaustor (14) is covered with the air filtration media (141) of not discharge opeing of aerofluxus, it is characterized in that; Less than 25.00kPa, said air filtration media (141) is installed in the end that exhaustor (14) stretches into dropping funnel (2) inner chamber to the bubble point pressure of said medical filtration medium (21) greater than 7.85kPa.
9. the said according to Claim 8 safe transfusion system based on the bubble point pressure principle is characterized in that, said medical filtration medium (21) less than 1.5kPa pressure reduction the time flow less than 1.0mL/min.
10. the said according to Claim 8 safe transfusion system based on the bubble point pressure principle is characterized in that, said air filtration media (141) is installed in the end (144) that exhaustor (14) stretches into dropping funnel (2) inner chamber one end.
11. the said according to Claim 8 safe transfusion system based on the bubble point pressure principle is characterized in that, said exhaustor (14) is the hollow pipe of outer wall sealing, and it is one section or is formed by connecting the multistage hollow pipe.
12., it is characterized in that an end of said exhaustor (14) is communicated with last capping or the sidewall of dropping funnel lid (12) and connects with the external world according to the said automatic exhaust safety transfusion device of claim 11 based on the bubble point pressure principle.
13. said according to Claim 8~12 safe transfusion system based on the bubble point pressure principle is characterized in that, said exhaustor (14) and the extraneous air exit (142) that connects locate to be equipped with one can open or close air exit block (143).
CN2011102783623A 2010-09-12 2011-09-09 Safety infusion set on basis of bubble point pressure principle Pending CN102553031A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2011102783623A CN102553031A (en) 2010-09-12 2011-09-09 Safety infusion set on basis of bubble point pressure principle

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN201020539685.4 2010-09-12
CN201020539685 2010-09-12
CN2010102901165A CN102000373A (en) 2010-06-07 2010-09-18 Manufacturing method of safe transfusion system based on bubbling point pressure principle
CN201010290116.5 2010-09-18
CN2011102783623A CN102553031A (en) 2010-09-12 2011-09-09 Safety infusion set on basis of bubble point pressure principle

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103830808A (en) * 2014-03-24 2014-06-04 北京伏尔特技术有限公司 Automatic liquid stop drip chamber
CN107206160A (en) * 2015-02-09 2017-09-26 株式会社小林 The preceding method of disposal of bottle needle tubing set and the transfusion group covered using this bottle of needle tubing
CN107427628A (en) * 2015-03-26 2017-12-01 贝克顿·迪金森公司 Improved anti-desiccation film

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103830808A (en) * 2014-03-24 2014-06-04 北京伏尔特技术有限公司 Automatic liquid stop drip chamber
CN107206160A (en) * 2015-02-09 2017-09-26 株式会社小林 The preceding method of disposal of bottle needle tubing set and the transfusion group covered using this bottle of needle tubing
CN107206160B (en) * 2015-02-09 2022-03-25 株式会社小林 Bottle needle tube sleeve and front disposal method of infusion set using same
CN107427628A (en) * 2015-03-26 2017-12-01 贝克顿·迪金森公司 Improved anti-desiccation film
CN107427628B (en) * 2015-03-26 2020-05-19 贝克顿·迪金森公司 Improved anti-drying membrane

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Application publication date: 20120711