CN102552691B - External application Chinese medicinal composition for treating cystic hyperplasia of breast - Google Patents

External application Chinese medicinal composition for treating cystic hyperplasia of breast Download PDF

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CN102552691B
CN102552691B CN2012100163940A CN201210016394A CN102552691B CN 102552691 B CN102552691 B CN 102552691B CN 2012100163940 A CN2012100163940 A CN 2012100163940A CN 201210016394 A CN201210016394 A CN 201210016394A CN 102552691 B CN102552691 B CN 102552691B
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breast
external application
chinese medicinal
treatment
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CN102552691A (en
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邹晓
兰克涛
耿传信
张春玲
苏天慧
邹俊哲
韩洁
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Qingdao Central Hospital
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Abstract

The invention relates to an external application Chinese medicinal composition for treating cystic hyperplasia of breast. The external application Chinese medicinal composition comprises the following bulk pharmaceuticals in parts by weight: 20-2,000 parts of garden balsam stem, 4-400 parts of frankincense, 4-400 parts of myrrh, 5-480 parts of indian iphigenia bulb, 4-400 parts of cowherb seed, 4-400 parts of pangolin, 6-600 parts of honeycomb, 4-400 parts of green tangerine peel, 6-600 parts of tangerine seed and 2-120 parts of borneol. The compatibility of a Chinese medicinal formula adopted in the invention is consistent with the principle of syndrome differentiation and treatment of cystic hyperplasia of breast. In a treatment method, the external application Chinese medicinal composition is mainly used for dispersing the depressed liver-energy, relieving pain, invigorating blood circulation, activating the channels and eliminating stagnation. According to breast nodule powder in a prescription, and the treatment principle of intramammary nodules includes promoting qi circulation, removing obstruction, reducing phlegm, resolving masses, dissolving stasis and relieving pain, and is just matched with the pathogenesis of intramammary nodules. Through external application, the medicament can permeates into a human body through pores, plays a role in clearing and activating thechannels and collaterals, and directly reaches an affected site, so that a treatment effect is achieved.

Description

A kind of Traditional Chinese Medicine for external application compositions for the treatment of cystic hyperplasia of breast
Technical field
The invention belongs to the medicine technical field of cystic hyperplasia of breast, be specifically related to a kind of Traditional Chinese Medicine for external application compositions for the treatment of cystic hyperplasia of breast.
Background technology
Cystic hyperplasia of breast is commonly encountered diseases, the frequently-occurring disease of woman mammary gland disease, and sickness rate accounts for mastotic first place.Cystic hyperplasia of breast belongs to Chinese medicine " nodules of the breast " category, and its domestic and international progress is mainly reflected in several aspects in recent years:
(1) on the research of cystic hyperplasia of breast etiology and pathogenesis: mammary gland tissue is subjected to the impact of ovary estrogen and progestogen and physiological hypertrophy and the thickening of generating period, then affect the breast duct lobule when incomplete or the cell hyperplasia of connective tissue around it when restoring, be referred to as cystic hyperplasia of breast.Modern medicine is thought cystic hyperplasia of breast, and main pathogenic factor is the endocrine disturbance, comprise that the ovarian secretion lutein is not enough and cause that estrogen increases relatively, so due to estrogen increases and cause that lutein reduces relatively;
(2) research for the treatment of: western medicine mainly adopts the Drug therapys such as tamoxifen, asparagine, its endocrine is intervened adjustment, but clinical efficacy is undesirable, and has serious toxic and side effects.In the traditional Chinese medical science field treatment of primary disease is mainly contained simple dialectical opinion and control, folk prescription plus-minus and Western medicine therapeutic alliance two classes.But with the quickening pace of modern life, the change of women's social pressure increasing, modern way of life and dietary habit, that causes menarche reaches the endocrine disturbance in advance, cause the patient of cystic hyperplasia of breast constantly to increase, aggravation, the serious symptom of bimastism pain has affected patient's work and life, wherein canceration occurs in the patient of 1-3%, only control with dialectical opinion and all patients of the very difficult treatment of folk prescription plus-minus, and exist the patient and can not adhere to for a long time the drawback of taking medicine, cause therapeutic effect poor, the heavy serious consequence of patients ' psychological burden.
Therefore, find a kind of for the patient provide medicine convenient, be easy to adhere to, thereby improve curative effect, alleviate the patient suffering, improve life and work quality, prevent that the Traditional Chinese Medicine for external application preparation of canceration is particularly important.
Summary of the invention
The purpose of this invention is to provide a kind of Traditional Chinese Medicine for external application preparation of effective treatment cystic hyperplasia of breast, be used for the treatment of cystic hyperplasia of breast, brought into play the low advantage of herbal toxic effect, for the patient provides cheap, easy, effective Therapeutic Method.
Chinese medicine preparation of the present invention includes the crude drug of following parts by weight:
Herba speranskiae tuberculatae 20-2000 part, Olibanum 4-400 part, Myrrha 4-400 part, Pseudobulbus Cremastrae Seu Pleiones 5-480 part,
Semen Vaccariae 4-400 part, Squama Manis 4-400 part, Nidus Vespae 6-600 part, Pericarpium Citri Reticulatae Viride 4-400 part
Semen Citri Reticulatae 6-600 part, Borneolum Syntheticum 2-120 part.
The preferable range of above-mentioned raw materials medicine umber is:
Herba speranskiae tuberculatae 100-1000 part, Olibanum 20-200 part, Myrrha 2-200 part, Pseudobulbus Cremastrae Seu Pleiones 24-240,
Semen Vaccariae 20-200 part, Squama Manis 20-200 part, Nidus Vespae 30-300 part, Pericarpium Citri Reticulatae Viride 2-200,
Semen Citri Reticulatae 30-300 part, Borneolum Syntheticum 6-60 part.
The best ratio of above-mentioned raw materials medicine umber is:
500 parts of Herba speranskiae tuberculataes, 100 parts of Olibanums, 100 parts of Myrrhas, 120 parts of Pseudobulbus Cremastrae Seu Pleioness,
100 parts of Semen Vaccariae, 100 parts of Squama Maniss, 150 parts in Nidus Vespae, 100 parts on Pericarpium Citri Reticulatae Viride,
150 parts of Semen Citri Reticulataes, 30 parts of Borneolum Syntheticums.
Medicine of the present invention is topical agent, is after each raw material is taken by weighing by proportioning, grinds preparation with 120 mesh sieves, in the gauze bag of packing into or in the medicine medicated bra.
Its compatibility of Chinese prescription that the present invention adopts meets the principle of cystic hyperplasia of breast determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, and Therapeutic Method is with the depressed liver-energy dispersing and QI regulating pain relieving, and the promoting blood circulation to remove obstruction in the collateral eliminating stagnation is main.The side is loose with nodule in the breast, has embodied the Therapeutic Principle of nodules of the breast for promoting QI circulation for relieving depression, dissipating phlegm and resolving masses, stasis-dispelling and pain-killing, just is in step with the pathogenesis of nodules of the breast.Drug external can make medicine enter space between skin and muscles from pore, and dredge the meridian passage makes the medicine sick institute that goes directly, thereby reaches therapeutic effect.
The specific embodiment
Solution of the present invention is based on motherland's medical science to understanding and the Therapeutic Principle of cystic hyperplasia of breast.Sick it " nodules of the breast " category of TCM Gynecology that belongs to of cystic hyperplasia of breast, whenever by depressed rage impairing the liver, worry impairing spleen causes qi depression to blood stasis, expectorant curdled milk network and nucleation.Breast belongs to stomach, and nipple belongs to liver, and breast is again the tube chamber of QI and blood milk circulation, should lead to and should not close.Depressed rage impairing the liver, stagnation of liver-QI is the stagnation of QI then, transverse invasion of hyperactive liver-QI then of a specified duration, the stomach pulse is obstructed, qi depression to blood stasis, venation is blocked, stagnation of QI and blood may bring about pain, the solidifying then caking of expectorant.So Therapeutic Method is with the depressed liver-energy dispersing and QI regulating pain relieving, the promoting blood circulation to remove obstruction in the collateral eliminating stagnation is main.Side's Olibanum, Myrrha, Semen Vaccariae, Squama Manis are with the vital energy regualting and blood circulation-promoting removing obstruction in the collateral to relieve pain; Subside a swelling with dissipating phlegm and resolving masses with Nidus Vespae; Herba speranskiae tuberculatae has the deep power of collateral dredging, and Borneolum Syntheticum has special fragrance, and penetration power is strong, is easy to Transdermal absorption, also can together with some other Drug Percutaneous Absorption, can improve curative effect simultaneously.Herbal medicines for external use can make medicine enter space between skin and muscles from pore, and dredge the meridian passage makes the medicine sick institute that goes directly.
The invention will be further described below in conjunction with specific embodiment.
Embodiment 1
Present embodiment is for making the external application of medicine sandbag, the raw material for standby of the following weight of the screening of learning from else's experience, purification: Herba speranskiae tuberculatae 50g, Olibanum 10g, Myrrha 10g, Pseudobulbus Cremastrae Seu Pleiones 12g, Semen Vaccariae 10g, Squama Manis 10g, Nidus Vespae 15g, Pericarpium Citri Reticulatae Viride 10g, Semen Citri Reticulatae 15g, Borneolum Syntheticum 3g
Adopt following method preparation:
(1) taking by weighing each crude drug by proportioning raw materials is ground with 120 mesh sieves; (2) get 20-30g, in the gauze bag of packing into, yarn bag size 3cm * 3cm is advisable; When (3) making the yarn bag, the side that do not contact with breast is accompanied by plastic sheeting, outwards distributes to prevent that the efficacy of a drug is too fast.
Using method: before menstrual onset 3-7 days, this sandbag is worn on the medicated bra of mastalgia place or lump corresponding site, advise patient every day voluntarily at breast caking place massage medicated bag for several times, pasted 1 time, and pasted per month 3 times in every 2-3 days.
Embodiment 2
Present embodiment is for wearing the medicine medicated bra, the raw material for standby of the screening of learning from else's experience, the following weight that purifies: Herba speranskiae tuberculatae 50g, Olibanum 10g, Myrrha 10g, Pseudobulbus Cremastrae Seu Pleiones 12g, Semen Vaccariae 10g, Squama Manis 10g, Nidus Vespae 15g, Pericarpium Citri Reticulatae Viride 10g, Semen Citri Reticulatae 15g, Borneolum Syntheticum 3g
Adopt following method preparation:
(1) taking by weighing each crude drug by proportioning raw materials is ground with 120 mesh sieves; (2) get 20-30g, the liniment medicated bra of packing into.
Using method: before menstrual onset 3-7 days, correctly wear the medicine medicated bra, advise patient every day voluntarily at breast caking place massage and drug medicated bra for several times, pasted 1 time, and pasted per month 3 times in every 2-3 days.
For a better understanding of the present invention, below by experiment the example further set forth effective effect of invention medicine, experimental example comprises:
The treatment group Therapeutic Method: before menstrual onset 3-7 days, correctly wear the medicine medicated bra, advise patient every day voluntarily at breast caking place massage and drug medicated bra for several times, pasted 1 time, and pasted per month 3 times in every 2-3 days.
The treatment of control group method: ease pill for oral administration, serveing on 3 months is a course for the treatment of.
All observe two courses for the treatment of for two groups, after the drug withdrawal with examining half a year.
Therapeutic evaluation: treat 40 examples (result such as following table) in my institute with the method, clinical observation shows that therapeutic effect is good, after treatment most of cystic cyclomastopathy patient periodically pain obviously alleviate and can touch the tenderness lump and obviously dwindle or disappear.
Figure BDA0000132140860000031
Result in clinical application shows that the Traditional Chinese Medicine for external application preparation for the treatment of cystic hyperplasia of breast of the present invention has good therapeutic effect, has good application prospect.

Claims (1)

1. Chinese medicine composition for the treatment of cystic hyperplasia of breast, described Chinese medicine composition is topical agent, is comprised of the crude drug of following parts by weight: 500 parts of Herba speranskiae tuberculataes, 100 parts of Olibanums, 100 parts of Myrrhas, 120 parts of Pseudobulbus Cremastrae Seu Pleioness, 100 parts of Semen Vaccariae, 100 parts of Squama Maniss, 150 parts in Nidus Vespae, 100 parts on Pericarpium Citri Reticulatae Viride, 150 parts of Semen Citri Reticulataes, 30 parts of Borneolum Syntheticums.
CN2012100163940A 2012-01-18 2012-01-18 External application Chinese medicinal composition for treating cystic hyperplasia of breast Expired - Fee Related CN102552691B (en)

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Inventor after: Zou Xiao

Inventor after: Lan Ketao

Inventor after: Geng Chuanxin

Inventor after: Zhang Chunling

Inventor after: Su Tianhui

Inventor after: Zou Junzhe

Inventor after: Han Jie

Inventor before: Zou Xiao

Inventor before: Lan Ketao

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Free format text: CORRECT: INVENTOR; FROM: ZOU XIAO LAN KETAO SU TIANHUI ZHANG CHUNLING GENG CHUANXIN ZOU JUNZHE HAN JIE TO: ZOU XIAO LAN KETAO GENG CHUANXIN ZHANG CHUNLING SU TIANHUI ZOU JUNZHE HAN JIE

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