CN102525433B - Biomedical signal analog instrument - Google Patents
Biomedical signal analog instrument Download PDFInfo
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- CN102525433B CN102525433B CN201110436650.7A CN201110436650A CN102525433B CN 102525433 B CN102525433 B CN 102525433B CN 201110436650 A CN201110436650 A CN 201110436650A CN 102525433 B CN102525433 B CN 102525433B
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Abstract
The invention relates to a biomedical signal analog instrument which comprises a central processing unit and an analog signal output circuit. The central processing unit is connected with the analog signal output circuit through a single chip machine which comprises a D/A (digital/analog) conversion output. The analog signal output circuit comprises an electrocardiogram data analog circuit, a respiratory data analog circuit, an invasive blood pressure data analog circuit and a body temperature data analog circuit. The biomedical signal analog instrument can be used for adjusting the analog quantity through man-machine conversation according to the difference of human body parameter characteristics, thereby improving the authenticity and the accuracy of the analog signal. The biomedical signal analog instrument has the man-machine interaction function, can realize the electrocardiogram analog and testing, the multi-channel non-invasive blood pressure control, the breathing analog data set and the output of a variety of common temperature, integrates four physiological parameters including electrocardiogram, respiration, body temperature and invasive blood pressure and can be used for testing and performing an experiment in any place where a patient monitor is used.
Description
Technical field
The invention belongs to medical Instrument field, relate in particular to a kind of biomedical signal analog instrument.
Background technology
Clinical conventional electrocardio at present, breathe, body temperature, invasive blood pressure measurement data often need to be converted to analogue signal analysis by its digital signal, especially domestic many ginseng analog meter signals output is both at home and abroad single at present, control mode is single, some controls are merely able to adopt the fixing manual analog temperature parameter of high-precision resistance, and be merely able to simulate one or both physiological parameters, there is no good human-computer interaction interface, for this situation, the demand of wishing to obtain the analog quantity of surveyed data and can have analog waveform assisted diagnosis in order to meet doctor, need to develop a kind of Multi-functional analog instrument with good in interactive function of exporting and generating waveform output that several data signal is simulated.
Summary of the invention
The object of the invention is a kind of biomedical signal analog instrument technical scheme proposing for the problems referred to above, this scheme adopts the mode of digital-to-analogue conversion to export the human body many kinds of parameters collecting, and can be according to the difference of human parameters characteristic, by interactive mode, analog quantity is adjusted, improved verity and the accuracy of analogue signal.
To achieve these goals, technical scheme of the present invention is:
A kind of biomedical signal analog instrument, comprise CPU and analog signal output circuit, described CPU is by single-chip microcomputer connecting analog signal output apparatus, described single-chip microcomputer includes D/A conversion output, wherein, described analog signal output circuit comprises: electrocardiogram (ECG) data analog circuit, breath data analog circuit, invasive blood pressure digital simulation circuit and temperature data analog circuit;
Described electrocardiogram (ECG) data analog circuit comprises electric resistance partial pressure output circuit and D/A change-over circuit, and D/A change-over circuit is connected with single-chip microcomputer, and the simulation output contact resistance of D/A change-over circuit divides voltage follower circuit;
Described breath data analog circuit comprises controllable resistor rate-of-change circuit and variable baseline impedance circuit, and controllable resistor rate-of-change circuit connects the D/A conversion output of single-chip microcomputer;
Described invasive blood pressure digital simulation circuit comprises electric resistance partial pressure output circuit and D/A change-over circuit, and D/A change-over circuit is connected with single-chip microcomputer, and the simulation output contact resistance of D/A change-over circuit divides voltage follower circuit;
Described temperature data analog circuit comprises semifixed resistor circuit and digital regulation resistance, and digital regulation resistance is connected with single-chip microcomputer, and the resistance of digital regulation resistance is drawn pin and is connected with semifixed resistor circuit.
The controllable resistor rate-of-change circuit of described breath data analog circuit and variable baseline impedance circuit comprise that field effect transistor and controlled two-way four select a non-contact switch circuit, the grid of field effect transistor connects the D/A conversion output of single-chip microcomputer, the two-way selecting side X that controlled two-way four selects a non-contact switch circuit and selecting side Y are connected respectively source electrode and the drain electrode of field effect transistor, controlled two-way four selects the selected end in a non-contact switch circuit Si road to connect respectively the resistance of 4 different resistances as variable baseline impedance outfan, described controlled two-way four selects the selecting side of a non-contact switch circuit to connect the control output of single-chip microcomputer.
The electric resistance partial pressure output circuit of described electrocardiogram (ECG) data analog circuit comprises the artifical resistance point voltage follower circuit of heart rate and the artifical resistance point voltage follower circuit of pacemaker impulse signal, the artifical resistance of a described heart rate point voltage follower circuit is resistance series connection point voltage follower circuit, the artifical resistance of a described pacemaker impulse signal point voltage follower circuit comprises pulse amplitude power supply and variable resistance circuit bleeder circuit, described variable resistance bleeder circuit comprises that resistance and controllable multipath select a non-contact switch circuit, resistance is connected to controllable multipath and selects the selecting side of a non-contact switch circuit and be selected end, described pulse amplitude power supply is connected to controllable multipath and selects the selecting side of a non-contact switch circuit, described controllable multipath selects the control end of a non-contact switch circuit to connect the control output of single-chip microcomputer.
Described single-chip microcomputer connects the D/A change-over circuit of electrocardiogram (ECG) data analog circuit and described invasive blood pressure digital simulation circuit in synchronous serial communication mode, and the digital regulation resistance of temperature data analog circuit.
The beneficial effect that compared with the prior art the present invention produces is: can be according to the difference of human parameters characteristic, by interactive mode, analog quantity is adjusted, improve verity and the accuracy of analogue signal, there is good human-computer interaction function, ECG simulator and test are provided, multichannel invasive blood pressure control output, breathes analog data and sets, multiple common temperature output; The present invention, by electrocardio, breathing, body temperature, 4 kinds of physiological parameter set to equipment of invasive blood pressure, can test and test in the place of any use patient monitor.Adopt lithium battery and/or the power supply of linear adaptation device, can be recycled, reduce interfering signal, almost can be used for all patient monitoring armarium of health care industry, simultaneously also for training, assessment and preventive maintenance provide a primary condition.
Below in conjunction with accompanying drawing, embodiment is described in detail the present invention.
Brief description of the drawings
Fig. 1 is circuit structure block diagram of the present invention;
Fig. 2 is electrocardiogram (ECG) data analog circuit figure of the present invention;
Fig. 3 is breath data analog circuit figure of the present invention;
Fig. 4 is invasive blood pressure digital simulation circuit diagram of the present invention;
Fig. 5 is temperature data analog circuit figure of the present invention.
Detailed description of the invention
A kind of biomedical signal analog instrument embodiment, referring to Fig. 1, Fig. 2, Fig. 3, Fig. 4 and Fig. 5; Described analog meter comprises CPU 101 and analog signal output circuit, described CPU is LPC2136 by single-chip microcomputer 102(model) connecting analog signal output apparatus, described single-chip microcomputer includes D/A conversion output 102-1, wherein, described analog signal output circuit comprises: electrocardiogram (ECG) data analog circuit 103, breath data analog circuit 104, invasive blood pressure data (IBP data) analog circuit 105 and temperature data analog circuit 106; Wherein, described in the present embodiment, CPU is ARM9TDMI processor, described analog meter connects LCD touch screen 107, memorizer, clock generator and APB bus 108 (Advanced Peripheral Bus) in addition around CPU, single-chip microcomputer is that the serial ports 109 articulating by APB bus is connected with CPU, and APB bus connects respectively power management module 111, button administration module 112 and patient's medical data acquisition module 113 by the serial ports+SDI module 110 articulating.Wherein, described power management module includes power distribution circuit, and power distribution circuit is connected with lithium battery and linear power adapter; Described button administration module comprises that PVC film key and film key detect control circuit; Described patient's medical data acquisition module comprises multiple read interface circuit, can read the memorizer of any storage patient medical data information, for example USB storage or SD card memory etc. by read interface circuit.
Described electrocardiogram (ECG) data analog circuit comprises electric resistance partial pressure output circuit and D/A change-over circuit, and D/A change-over circuit is connected with single-chip microcomputer, and the simulation output contact resistance of D/A change-over circuit divides voltage follower circuit;
Described breath data analog circuit comprises controllable resistor rate of change and variable baseline impedance circuit, and controllable resistor rate of change connects the D/A conversion output of single-chip microcomputer;
Described invasive blood pressure digital simulation circuit comprises electric resistance partial pressure output circuit and D/A change-over circuit, and D/A change-over circuit is connected with single-chip microcomputer, and the simulation output contact resistance of D/A change-over circuit divides voltage follower circuit;
Described temperature data analog circuit comprises semifixed resistor circuit and digital regulation resistance, and digital regulation resistance is connected with single-chip microcomputer, and the resistance of digital regulation resistance is drawn pin and is connected with semifixed resistor circuit.
As shown in Figure 2, the electric resistance partial pressure output circuit of described electrocardiogram (ECG) data analog circuit comprises the artifical resistance point voltage follower circuit 201 of heart rate and the artifical resistance point voltage follower circuit 202 of pacemaker impulse signal.
The artifical resistance of a described heart rate point voltage follower circuit is by exporting after resistance R 201 and R202 series connection dividing potential drop, artifical resistance point voltage follower circuit directly connects the 2011 Ba road D/A outputs of D/A change-over circuit, and what D/A change-over circuit used is the chip that model is DAC7558IRHBRG4.
The artifical resistance of a described pacemaker impulse signal point voltage follower circuit comprises pulse amplitude power supply and variable resistance circuit bleeder circuit, described variable resistance circuit bleeder circuit comprises that resistance and controllable multipath select a non-contact switch circuit, resistance is connected to controllable multipath and selects the selecting side of a non-contact switch circuit and be selected end, described pulse amplitude power supply is connected to controllable multipath and selects the selecting side of a non-contact switch circuit, and described controllable multipath selects the control end of a non-contact switch circuit to connect the control output of single-chip microcomputer, wherein, what described pulse amplitude power supply used is 2.5 volts of DC sources 2021, described controllable multipath selects a non-contact switch circuit to comprise that Yi Ge mono-tunnel one selects five non-contact switch circuits (CD74HC4051PWR) 2022 and Yi Ge tri-tunnels one to select two non-contact switch circuits (CD74HC4053PWR) 2023, one selects the selected end in five non-contact switch circuit Wu roads to connect respectively the resistance R 203 of five different resistances, one selects the X Yu San road, selecting side one of five non-contact switch circuits to select the selected Duan mono-road X0 of two-way of two non-contact switch circuits, Y0 is connected with Z0, another road X1 of selected end, Y1 and Z1 connect power cathode simultaneously, three tunnels one select two non-contact switch circuit San road selecting side X, Y and Z together to connect the resistance R 204 of seven different resistances, and pulse amplitude power supply is connected to when controllable multipath selects the selecting side of a non-contact switch circuit and also connects power cathode by resistance R 205.
Above-mentioned electrocardiogram (ECG) data analog circuit can be realized more than 30 kind of arrhythmia and normal sinus rate, performance test ripple, pacing signal.Single-chip microcomputer unpacks the host computer data that receive be input to DAC7558IRHBRG4 conversion chip by SPI communication modes, this chip is selected to seal in and go out 12 8 passage D/A and is exported analog-converted data with the speed of 500 packets per second, taking 2.5V as with reference to source, adopt electric resistance partial pressure mode conditioning signal transformation range as 0～10mV, directly export V1～V6 analogue signal.D/A change-over circuit also has the right hand (RA) and the output of left hand (LA) signal simultaneously, the right hand and left hand signal are connected respectively to RA after following by operational amplifier 2012 again and LA leads on output wiring terminal post accordingly, the RL binding post at zero point of simulation output directly meets GND, and simulation GND receives the present embodiment setting zero line LL after following by operational amplifier leads on binding post.
One selects five non-contact switch circuits (CD74HC4051PWR) can produce five kinds of different voltage gear (2mv by electric resistance partial pressure, 4mv, 6mv, 8mv, 10mv), control in conjunction with LPC2136 single-chip microcomputer to CD74HC4051PWR analog switch, exportable these five kinds of pace-making voltage magnitudes, select the response time of two non-contact switch circuit CD74HC4053PWR analog switches to control the time of pace-making by single-chip microcomputer timer internal control three tunnels one simultaneously, be respectively 0.1ms, 0.5ms, 1.0ms, 1.5ms, five kinds of pacemaker impulse times of 2.0ms, exportable 25 kinds of different pacemaker impulse signals.
As shown in Figure 3, the controllable resistor rate of change of described breath data analog circuit and variable baseline impedance circuit comprise that it is CD74HC4052PWR that field effect transistor Q1 and controlled two-way four select a non-contact switch circuit 301(model), the grid of field effect transistor connects the D/A conversion output of single-chip microcomputer, controlled two-way four selects selecting side X and the selecting side Y of the two-way of a non-contact switch circuit to be connected respectively source electrode and the drain electrode of field effect transistor, controlled two-way four selects the selected end in a non-contact switch circuit Si road to connect respectively the resistance R 301 of 4 different resistances as variable baseline impedance outfan, the resistance value of different resistances is respectively 250 Ω of corresponding X0 and Y0, 500 Ω of corresponding X1 and Y1, 750 Ω of corresponding X2 and Y2, 1000 Ω of corresponding X3 and Y3, described controlled two-way four selects the selecting side of a non-contact switch circuit to connect the control output of single-chip microcomputer.
Described breath data analog circuit is simulated the resistance variations in thoracic cavity by a controlled resistance change rate and transformation range, the variation of body impedance while simulating human body respiration.LPC2136 single-chip microcomputer receives the digital packetized signals of host computer by serial ports, unpack and export different analog voltages by the inner D/A conversion of single-chip microcomputer pin according to communications protocol, by controlling the voltage transformation between SST4392 metal-oxide-semiconductor grid and source electrode, can derive the resistance variations between drain electrode and the source electrode of metal-oxide-semiconductor according to the V-gs characteristic curve of metal-oxide-semiconductor.The D/A pin of packing data control single chip computer LPC2136 by host computer is exported different voltage, can obtain respectively the transformation range of 0.2R, 0.5R, 1R, 3R and 0～150 breathing transformation rate.The baseline impedance that single-chip microcomputer LPC2136 obtains 500 Ω, 1000 Ω, 1500 Ω, 2000 Ω by control simulation on-off circuit CD74HC4052PWR changes, and finally on binding post, exports different simulated respiration signals.
As shown in Figure 4, described invasive blood pressure digital simulation circuit comprises that electric resistance partial pressure output circuit and D/A change-over circuit 401(model are BU2507FV), D/A conversion chip is connected with single-chip microcomputer, and the simulation output contact resistance of D/A conversion chip divides voltage follower circuit, electric resistance partial pressure output circuit in Fig. 4 is made up of resistance R 401 and the R402 of two groups of four different resistances of mutually connecting respectively, single-chip microcomputer receives host computer numeral packetized signals by serial ports, LPC2136 single-chip microcomputer unpacks and enters data into by SPI communication modes the D/A conversion chip that seals in and go out 10 6 passages, D/A change-over circuit is by passage AO1, AO2, AO4, AO6 exports each analog data, obtain the each analog data of invasive blood pressure by 0.1% 2.49K precision resistance and 10 Ω electric resistance partial pressures again, finally be connected on the PS2 socket of 46 cores, by IBP cable outputting analog signal (1 cable can only be exported the Simulation with I BP data of 1 passage).The present embodiment wound blood pressure data analog circuit is only applicable to 5V input, and outside 5V supply voltage is passed through operational amplifier and obtained 2.5 reference voltages of D/A conversion chip BU2507FV by electric resistance partial pressure.
As shown in Figure 5, described temperature data analog circuit comprises semifixed resistor circuit and digital regulation resistance (model is AD5259BRMZ10), and digital regulation resistance 501 is connected with single-chip microcomputer, digital regulation resistance draw pin contact resistance R501 and semifixed resistor RW output.Temperature data analog circuit can be simulated 4 kinds of human body temperature that pre-set, and freezing (0 DEG C/32
0f), hypothermia (24 DEG C/75.2
0f), normal (37 DEG C/98.6
0f) or fever (40 DEG C/104
0f).Pass through I by 10K fixed resistance value 256 stepping 0.1% high accuracy number potentiometers and LPC2136 single-chip microcomputer
2c communication modes is realized 4 kinds of simulation temperature datas, after the slide potentiometer of 200 ohm of the resistance of circuit 2 10M in parallel and series connection finely tune, be finally connected on PS2 socket, by body temperature cable output simulation temperature data.
Therefore in above-described embodiment, described single-chip microcomputer connects D/A change-over circuit and the D/A change-over circuit of described invasive blood pressure digital simulation circuit and the digital regulation resistance of temperature data analog circuit of electrocardiogram (ECG) data analog circuit in synchronous serial communication mode.
Described in the present embodiment, the operation principle of patient's medical data acquisition module is: by reading the case identified of storing in SD card interface circuit, can read the actual significant electrocardiogram (ECG) data running in clinical practice, the electrocardiogram (ECG) data that can identify case and be to be recorded such as the cardioelectric monitor such as electrocardiograph, monitor instrument is basis, coordinate the data message composition that records these data, data message comprises sample frequency, sampling precision, data type, baseline position, the information such as mark of calibrating, lead, and converts information to .txt file format.Conventionally the data format gathering comprises * ..atr, * ..dat, * ..hea, then converts the file of above-mentioned form to SD card discernible case form by switching software.The case waveform that central processing unit generates above-mentioned conversion afterwards shows at LCD touch screen, simultaneously in interactive mode by the analog signal output of this case of chip microcontroller, medical personnel can, from the comparative analysis patient's of analog signal output and waveform the state of an illness, reproduce case.
Described in the present embodiment, the operation principle of biomedical signal analog instrument is: taking ARM9TDMI processor as core processing unit, by the electrocardio of its storage inside, IBP Wave data, send to single-chip microcomputer by serial ports, single-chip microcomputer is by controlling the output of external D/A converter and self D/A module, and by the resistance conversion of IIC module controls digital regulation resistance, realize the simulation output of electrocardio, invasive blood pressure, breathing, temperature data, realize the collection playback of patient's medical data by SDI module and case switching software.
Claims (2)
1. a biomedical signal analog instrument, comprise CPU and analog signal output circuit, described CPU is by single-chip microcomputer connecting analog signal output apparatus, described single-chip microcomputer includes D/A conversion output circuit, it is characterized in that, described analog signal output circuit comprises: electrocardiogram (ECG) data analog circuit, breath data analog circuit, invasive blood pressure digital simulation circuit and temperature data analog circuit;
Described electrocardiogram (ECG) data analog circuit comprises electrocardiogram (ECG) data electric resistance partial pressure output circuit and electrocardiogram (ECG) data D/A change-over circuit, electrocardiogram (ECG) data D/A change-over circuit is connected with single-chip microcomputer, and the simulation output of electrocardiogram (ECG) data D/A change-over circuit connects electrocardiogram (ECG) data electric resistance partial pressure output circuit;
Described breath data analog circuit comprises controllable resistor rate-of-change circuit and variable baseline impedance circuit, and controllable resistor rate-of-change circuit connects the D/A conversion output circuit of single-chip microcomputer;
Described invasive blood pressure digital simulation circuit comprises blood pressure data electric resistance partial pressure output circuit and blood pressure data D/A change-over circuit, blood pressure data D/A change-over circuit is connected with single-chip microcomputer, and the simulation output of blood pressure data D/A change-over circuit connects blood pressure data electric resistance partial pressure output circuit;
Described temperature data analog circuit comprises semifixed resistor circuit and digital regulation resistance, and digital regulation resistance is connected with single-chip microcomputer, and the resistance of digital regulation resistance is drawn pin and is connected with semifixed resistor circuit;
The controllable resistor rate-of-change circuit of described breath data analog circuit and variable baseline impedance circuit comprise that field effect transistor and controlled two-way four select a non-contact switch circuit, the grid of field effect transistor connects the D/A conversion output circuit of single-chip microcomputer, two-way selecting side Zhong mono-selecting side, tunnel that controlled two-way four selects a non-contact switch circuit and another selecting side, road are connected respectively source electrode and the drain electrode of field effect transistor, controlled two-way four selects the selected end in a non-contact switch circuit Si road to connect respectively the resistance of 4 different resistances as variable baseline impedance circuit output end, described controlled two-way four selects the selecting side of a non-contact switch circuit to connect the control output circuit of single-chip microcomputer,
Described single-chip microcomputer connects the D/A change-over circuit of electrocardiogram (ECG) data analog circuit and described invasive blood pressure digital simulation circuit in synchronous serial communication mode, and the digital regulation resistance of temperature data analog circuit.
2. a kind of biomedical signal analog instrument according to claim 1, it is characterized in that, the electric resistance partial pressure output circuit of described electrocardiogram (ECG) data analog circuit comprises the artifical resistance point voltage follower circuit of heart rate and the artifical resistance point voltage follower circuit of pacemaker impulse signal, the artifical resistance of a described heart rate point voltage follower circuit is resistance series connection point voltage follower circuit, the artifical resistance of a described pacemaker impulse signal point voltage follower circuit comprises pulse amplitude power supply and variable resistance bleeder circuit, described variable resistance bleeder circuit comprises that resistance and controllable multipath select a non-contact switch circuit, resistance is connected to controllable multipath and selects the selecting side of a non-contact switch circuit and be selected end, described pulse amplitude power supply is connected to controllable multipath and selects the selecting side of a non-contact switch circuit, described controllable multipath selects the control end of a non-contact switch circuit to connect the control output circuit of single-chip microcomputer.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN208892553U (en) * | 2017-03-07 | 2019-05-24 | 铂元智能科技(北京)有限公司 | Wireless body temperature measuring device |
| CN106798546A (en) * | 2017-03-07 | 2017-06-06 | 铂元智能科技(北京)有限公司 | Data acquisition process terminal |
| CN108931955B (en) * | 2018-08-28 | 2023-12-26 | 康泰医学系统（秦皇岛）股份有限公司 | Analog output device for physiological signal |
| CN108931954A (en) * | 2018-08-28 | 2018-12-04 | 康泰医学系统（秦皇岛）股份有限公司 | Temperature signals simulation output equipment |
| CN109171685B (en) * | 2018-09-20 | 2021-10-08 | 芯海科技（深圳）股份有限公司 | Method, device and storage medium for simulating human physiological signals |
| CN109637241A (en) * | 2018-12-05 | 2019-04-16 | 成都泰盟软件有限公司 | A kind of virtual organism electric signal generator system |
| CN113907730B (en) * | 2021-10-19 | 2024-05-17 | 广州市番禺区中心医院(广州市番禺区人民医院、广州市番禺区心血管疾病研究所) | Invasive blood pressure monitor detection equipment and system |
| CN114927114B (en) * | 2022-06-29 | 2024-04-09 | 高创(苏州)电子有限公司 | Display device input circuit, display device and control method thereof |
| CN116469288B (en) * | 2023-04-06 | 2024-01-30 | 成都维信电子科大新技术有限公司 | Urodynamic analyzer simulation training system |
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| US7917774B2 (en) * | 2006-08-22 | 2011-03-29 | Pronk Technologies Inc. | Electrocardiograph and blood pressure signals simulator |
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Address after: Qin 066004 West Street in Hebei province Qinhuangdao City Economic and Technological Development Zone No. 112 Patentee after: Kangtai medical system (Qinhuangdao) Limited by Share Ltd Address before: Qin 066004 West Street in Hebei province Qinhuangdao City Economic and Technological Development Zone No. 112 Patentee before: Qinhuangdao Contec Medical Systems Co.,Ltd. |