CN102512548A - Toxin-removing and fat-dispelling capsule - Google Patents
Toxin-removing and fat-dispelling capsule Download PDFInfo
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Abstract
The invention relates to a toxin-removing and fat-dispelling capsule. Raw materials for the capsule comprise senna leaves, bighead atractylodes rhizome, Stephania tetrandra, fleece-flower root, rhizoma alismatis, peanut shell, radish seed, haw, Radix Astragali and epimeddium. According to the invention, effective ingredients capable of removing toxin and dispelling fat are extracted from pure traditional Chinese medicines; the capsule can clear blood vessels, blood fat and blood clots, has a remarkable effect on treating heart diseases, heart failure, heart clot, cerebral infarction, cerebral thrombus and hemiplegia, has the function of repairing blood vessels, plays an active role in improving kidney function and enhancing resistance and immunity and has the advantages of no toxic and side effects and low cost.
Description
Technical field
The present invention relates to a kind of detoxicating and hypolipemic capsule.
Background technology
At present cleaning blood vessel or dredging vascellum can be treated cardiovascular and cerebrovascular disease such as heart failure, heart clot, brain clot, encephalocoele stalk, cerebral thrombosis, and have the medicine of functions such as blood pressure lowering, blood fat reducing, reparation blood vessel to be Western medicine mostly, can only alleviate above-mentioned disease symptom; Be difficult to recovery from illness; And the bounce-back rate is than higher after the drug withdrawal, and simultaneously traditional medicine side effect is big, and liver, the renal function taken for a long time human body cause very big damage; And treatment time is long, and drug effect is single.Current, do not utilize pure Chinese medicine to clear up blood vessel cleaning blood fat cleaning clot, treat the medicine of cardiovascular and cerebrovascular disease and blood fat reducing simultaneously, be difficult to meet the need of market.
Summary of the invention
The purpose of this invention is to provide a kind of detoxicating and hypolipemic capsule, utilize and extract the active ingredient that contains detoxicating and hypolipemic in the Chinese medicine, can clear up blood vessel, the cleaning blood fat; The cleaning clot can be treated heart disease, heart failure, heart clot, brain clot, encephalocoele stalk, cerebral thrombosis, hemiplegia; And respond well, and have the function of repairing blood vessel, improve renal function; Build up resistance and immunity has positive role, and have no side effect, cost is low.
The present invention contains the crude drug of secondary compatibility; Compatibility takes off and states materials of weight proportions for the first time: rush down 2～8 parts on leaf, 12～18 parts of the Rhizoma Atractylodis Macrocephalaes, 12～18 parts of Radix Stephaniae Tetrandrae, 17～23 parts of the Radixs Polygoni Multiflori, 17～23 parts of Rhizoma Alismatis, 22～28 parts of Pericarppium arachidis hypogaeaes, 27～33 parts of Semen Raphanis, 27～33 parts of Fructus Crataegis, 27～33 parts of the Radixs Astragali, 27～33 parts of Herba Epimedii;
Earlier above-mentioned each medicated powder is broken to graininess, inserts in the container, add the water that accounts for 3～4 times of above-mentioned each medicine cumulative volumes, 100 ℃ of water temperatures; Boiled 40 minutes, and filtered, take out clear liquid, spice adds the decocting in water that accounts for 2～3 times of above-mentioned each medicine volume total amounts again and takes out clear liquid after 40 minutes; Repeat once again, 3 decocting liquids are merged, freezing precipitation was got the Chinese herbal medicine extractum that supernatant concentration becomes water content 45-50% after 20 hours; Add ethanol and make extractum contain the alcohol amount to reach 70%, left standstill 24 hours, the leaching supernatant reclaims ethanol; Be concentrated into the extractum of relative density 1.30～1.32, use machine dry, dry thing is ground into fine powder, process and refine concentrated powder; Compatibility is got Fructus Crataegi and Pericarppium arachidis hypogaeae again and is worn into 120～200 order fine powders for the second time, processes and gives birth to Fructus Crataegi and the peanut hull meal that extracts; Concentrate by per 1 jin of refinement of compatibility for the first time and to add 0.12 jin of Fructus Crataegi powder in the powder; 0.08 jin of peanut hull meal, the compatibility refinement concentrates adding Fructus Crataegi powder and peanut hull meal in the powder in the first time, behind the abundant mix homogeneously of mixed material medicine; Pack in No. 1 commercially available capsule, the weight of every capsules is 40mg.Compatibility took off and stated materials of weight proportions wherein said first time: rush down 5 parts on leaf, 5 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Radix Stephaniae Tetrandrae, 20 parts of the Radixs Polygoni Multiflori, 20 parts of Rhizoma Alismatis, 25 parts of Pericarppium arachidis hypogaeaes, 30 parts of Semen Raphanis, 30 parts of Fructus Crataegis, 30 parts of the Radixs Astragali, 30 parts of Herba Epimedii.
Usually oral, one time 2～3,3 times on the one.
Solution among the present invention is according to traditional Chinese medical science rule, i.e. enriching yin and nourishing kidney, and blood circulation promoting and blood stasis dispelling, eliminating stasis to stop pain, it is long-pending to help digestion, bactericidal antiphlogistic, clearing away damp-heat rushes down the poison fire.The present invention forms according to above-mentioned rule, can blood circulation promoting and blood stasis dispelling, and eliminating stasis to stop pain, clearing away damp-heat, the pipe that purifies the blood, the fat that purifies the blood, the piece that purifies the blood rush down the poison fire, and counteracting toxic substances, eliminating stagnation again can eliminating stasis to stop pain, the collateral dredging of enriching blood.The leaf that rushes down of the present invention, nature and flavor are bitter, cold, have the intestinal stasis relieving of purging heat and play the cometabolism effect.The Rhizoma Atractylodis Macrocephalae, nature and flavor are sweet, bitter, warm, have spleen reinforcing, dampness, and significant promoting urination to remove dampness effect is arranged, and can play the cometabolism effect simultaneously.Radix Stephaniae Tetrandrae, nature and flavor are bitter, cold, have capable water, rush down the effect of damp-heat in lower-JIAO, the swollen tympanites of harnessing the river, the tinea scabies is swollen.The Radix Polygoni Multiflori, nature and flavor are bitter, sweet, puckery, warm, have invigorating the liver and kidney, hold back vital essence, strengthening bone and muscle, relieving constipation, antidotal effect, can control the dryness of the intestine constipation, scrofula.Rhizoma Alismatis, nature and flavor are sweet, be slightly cold, and the effect of eliminating dampness by diuresis, promoting urination to remove dampness is arranged, and can control damp-heat in the urinary bladder, dysuria, edema distension.Pericarppium arachidis hypogaeae is selected from sophisticated Pericarppium arachidis hypogaeae, and cold is dried the back for finished product, belongs to crude fibre, have help digestion long-pending, the congestion that looses, blood fat reducing, oil removing, the effect of dehumidifying.Semen Raphani, property acrid-sweet flavor, flat has therapeutic method to keep the adverse QI flowing downwards Dingchuan, and the deflated effect that eliminates indigestion and phlegm can be controlled the cough phlegm dyspnea, and stagnation of QI due to dyspepsia is uncomfortable in chest.Fructus Crataegi, sweet, the tepor of nature and flavor acid, have help digestion long-pending, the congestion that looses, blood fat reducing, the effect of blood pressure lowering, inhibitory action.The Radix Astragali, nature and flavor are bitter, cold, have clearing away damp-heat, the invigorating primordial QI effect with immunity of building up one's resistance to disease.Herba Epimedii, nature and flavor are hot, warm, have invigorating the liver and kidney, bone and muscle strengthening, supporing yang benefit is smart, the effect with immunity of building up one's resistance to disease.
The present invention utilizes and extracts the active ingredient that contains detoxicating and hypolipemic in the pure Chinese medicine, can clear up blood vessel, the cleaning blood fat; The cleaning clot can be treated heart disease, heart failure, heart clot, brain clot, encephalocoele stalk, cerebral thrombosis, hemiplegia; And respond well, and have the function of repairing blood vessel, improve renal function; Build up resistance and immunity has positive role, and have no side effect, cost is low.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the present invention is to cleaning vascular treatment heart disease, (heart failure, heart clot, brain clot, encephalocoele stalk, cerebral thrombosis; Hemiplegia, cleaning blood vessel are repaired blood vessel, the while can be played patients such as falling mild hypertension, high blood viscosity, hyperlipidemia has significant curative effect; And short treating period, the bounce-back rate is low, taking convenience; Low price has no side effect.Of the present invention one the course of treatment cost only be 10% of the traditional drugs cost course of treatment, can save patient's expense expenditure greatly.Show that through animal acute toxicity test underproof animal end sees any toxic reaction, its main organs does not have tangible change yet, and mice is 40g crude drug/kg to the maximum tolerated dose of medicine of the present invention, is 150 times of clinical people's consumption, and safety of medicine is reliable.
2, human body there is toxin expelling, the liver heat removing dampness removing, the effect of enhances human body resistance and immunity to hemiplegia, sexual impotence, reparation blood vessel, improve renal function, is built up resistance and immunity has positive role.
For showing therapeutic effect of the present invention, issue " Chinese medicine card diagnosis criterion of therapeutical effect " 1995.1 according to State Administration of Traditional Chinese Medicine through the XXXXX academy of traditional Chinese medicine.(1) cures produce effects: do not have symptom before the treatment, and prolong and do not send out the author more than 1 year.(2) effective: symptom is more preceding obviously to be alleviated, and it is normal that symptom is recovered basically.(3) invalid: symptom such as preceding.Various indexs and preceding index and the diagnostic data contrast of taking medicine after clinical observation is taken medicine.Clinical person's diagnostic criteria be make a definite diagnosis through hospital suffer from cardiovascular and cerebrovascular disease, coronary heart disease, heart clot, clot in the brain, encephalocoele stalk, cerebral thrombosis and the heart disease that causes by hypertension, high blood viscosity, hyperlipidemia.Mild hypertension, diseases such as high blood viscosity, hyperlipidemia.Case is selected: 145 examples suffer from mild hypertension, diseases such as high blood viscosity, hyperlipidemia, wherein male 110 examples, women 35 examples.80 examples suffer from clot in cardiovascular and cerebrovascular disease, coronary heart disease, heart clot, the brain, encephalocoele stalk, cerebral thrombosis, comprising the heart disease that causes by hypertension, high blood viscosity, hyperlipidemia, and wherein male 50 examples, women 30 examples.The course of disease did not wait in 1～3 year, and the patient accounts for 60% more than 1 year.Clinical person's consumption oral (embodiment 2 is made), one time 2～3,3 times on the one.
The result is following; Obtain promising result through the court's clinical observation 225 examples.The treatment mild hypertension, disease 145 examples such as high blood viscosity, hyperlipidemia hyperlipidemia are cured produce effects 96 examples, effective 43 examples, invalid 6 examples, effective percentage reaches more than 95%.Clot, encephalocoele stalk, cerebral thrombosis disease 80 examples such as (comprising the heart disease that is caused by hypertension, high blood viscosity, hyperlipidemia) are cured produce effects 39 examples in treatment cardiovascular and cerebrovascular disease, coronary heart disease, heart clot, the brain, effective 31 examples, and invalid 10 examples, effective percentage reaches more than 87%.Wherein to the treatment mild hypertension, cure produce effects group drug withdrawal 3 courses of treatment in disease 145 examples such as high blood viscosity, hyperlipidemia hyperlipidemia after, measure various indexs after the drug withdrawal again, the unusual person of various indexs is 2%.In treatment cardiovascular and cerebrovascular disease, coronary heart disease, heart clot, the interior clot of brain, encephalocoele stalk, cerebral thrombosis disease 80 examples such as (comprising the heart disease that causes by hypertension, high blood viscosity, hyperlipidemia); After curing produce effects group drug withdrawal 3 courses of treatment; Measure various indexs after the drug withdrawal again, the unusual person of various indexs is 3%.
Model case wherein: (1) high X, man, 53 years old.Seek medical advice to hospital because of normal dizziness between in February, 2007, the figure is fat, looks into T-CHOL (T-CHO/mmoI/L) 8.63 on an empty stomach; Triglyceride (TG/mmoI/L) 4.08; High density matter protein cholesterol (HDL-C/mmoI/L) 2.65; Low-density matter protein cholesterol (LDL-C/mmoI/L) 4.75; Alanine aminotransferase (ALT/U/L) 50; Glycolated hemoglobin (HbAI/%) 7.7.Color ultra multiple strong echo of left carotid crotch and the low echo speckle of showing of cervical region blood vessel; About 0.7x0.27cm; The about 0.8x0.17cm of the visible size of right carotid crotch mixes the echo speckle, the tube chamber obvious stenosis, and the bilateral carotid arteries AP forms.Take " detoxicating and hypolipemic capsule ", oral, one time 3,3 times on the one.Serve on 3 courses of treatment 30 days one courses of treatment, and diet control does not have dizzy symptom.Look into after 3 courses of treatment and look into T-CHOL (T-CHO/mmoI/L) 3.73 on an empty stomach; Triglyceride (TG/mmoI/L) 0.88; High density matter protein cholesterol (HDL-C/mmoI/L) 1.58; Low-density matter protein cholesterol (LDL-C/mmoI/L) 1.65; Alanine aminotransferase (ALT/U/L) 36; Glycolated hemoglobin (HbAI/%) 5.6.The ultra low echo speckle of left carotid crotch that shows of cervical region blood vessel coloured silk, about 0.1x0.07cm, the about 0.1x0.05cm of the visible size of right carotid crotch mixes the echo speckle, and tube chamber is not seen obvious stenosis, and the bilateral carotid arteries AP dwindles.After drug withdrawal March, the routine blood test testing result is all in normal range.
(2) Guo XX, the woman, 63 years old, made a definite diagnosis coronary heart disease, three pathological changes, CAC in 2007, coronary artery obvious stenosis thrombosis is had a blood test and is pressed high pressure 150, low pressure 96.Tired, heavy dusk.Because health, be not suitable for putting up a bridge and the support operation, take " detoxicating and hypolipemic capsule ", oral, one time 3,3 times on the one.30 days one courses of treatment, serve on 4 courses of treatment.Have a blood test after 4 courses of treatment and press high pressure 120, low pressure 80.Color ultra look into coronary artery and do not see that the obvious stenosis blood flow is smooth, do not had tired, heavy dusk phenomenon.Drug withdrawal does not have ill symptoms so far.
(3) in XX, the man, 44 years old, the workman made a definite diagnosis cerebral thrombosis, walking disorder in 2007, and the both sides trick is inharmonious, needs people's assisted ambulation, can't take care of oneself.Take " detoxicating and hypolipemic capsule ", oral, one time 3,3 times on the one.30 days one courses of treatment, serve on 5 courses of treatment.Be able to support oneself after 5 courses of treatment and walk alone, need not people's assisted ambulation, life can be taken care of oneself, and it is poor slightly that left side foot and all the other limbs are coordinated, and all the other are normal.
The specific embodiment
Embodiment 1: compatibility for the first time takes by weighing raw material by following proportioning: rush down leaf 3g, Rhizoma Atractylodis Macrocephalae 18g, Radix Stephaniae Tetrandrae 12g, Radix Polygoni Multiflori 17g, Rhizoma Alismatis 23g, Pericarppium arachidis hypogaeae 28g, Semen Raphani 33g, Fructus Crataegi 27g, Radix Astragali 33g, Herba Epimedii 27g.
Earlier above-mentioned each medicated powder is broken to graininess, inserts in the container, add the water that accounts for 3～4 times of above-mentioned each medicine cumulative volumes, 100 ℃ of water temperatures; Boiled 40 minutes, and filtered, take out clear liquid, spice adds the decocting in water that accounts for 2～3 times of above-mentioned each medicine volume total amounts again and takes out clear liquid after 40 minutes; Repeat once again, 3 decocting liquids are merged, freezing precipitation was got the Chinese herbal medicine extractum that supernatant concentration becomes water content 45-50% after 20 hours; Add ethanol and make extractum contain the alcohol amount to reach 70%, left standstill 24 hours, the leaching supernatant reclaims ethanol; Be concentrated into the extractum of relative density 1.30～1.32, use machine dry, dry thing is ground into fine powder, process and refine concentrated powder;
Compatibility is got Fructus Crataegi and Pericarppium arachidis hypogaeae again and is worn into 120～200 order fine powders for the second time, processes and gives birth to Fructus Crataegi and the peanut hull meal that extracts; Concentrate by per 1 jin of refinement of compatibility for the first time and to add 0.12 jin of Fructus Crataegi powder in the powder; 0.08 jin of peanut hull meal, the compatibility refinement concentrates adding Fructus Crataegi powder and peanut hull meal in the powder in the first time, behind the abundant mix homogeneously of mixed material medicine; Pack in No. 1 commercially available capsule, the weight of every capsules is 40mg.
Usually oral, one time 2～3,3 times on the one.
Embodiment 2: different with embodiment 1 is: compatibility takes by weighing raw material by following proportioning for the first time: rush down leaf 5g, Rhizoma Atractylodis Macrocephalae 15g, Radix Stephaniae Tetrandrae 15g, Radix Polygoni Multiflori 20g, Rhizoma Alismatis 20g, Pericarppium arachidis hypogaeae 25g, Semen Raphani 30g, Fructus Crataegi 30g, Radix Astragali 30g, Herba Epimedii 30g.So all the other and embodiment 1 are no longer tired stating.
In a word, the present invention has to utilize in the pure Chinese medicine and extracts the active ingredient that contains detoxicating and hypolipemic, can clear up blood vessel, the cleaning blood fat; The cleaning clot can be treated heart disease, heart failure, heart clot, brain clot, encephalocoele stalk, cerebral thrombosis, hemiplegia; And effect is remarkable, and has the function of repairing blood vessel, improves renal function; Build up resistance and immunity has positive role, and have no side effect the advantage that cost is low.
Claims (2)
1. detoxicating and hypolipemic capsule, it is characterized in that: it contains the crude drug of secondary compatibility;
Compatibility takes off and states materials of weight proportions for the first time: rush down 2～8 parts on leaf, 12～18 parts of the Rhizoma Atractylodis Macrocephalaes, 12～18 parts of Radix Stephaniae Tetrandrae, 17～23 parts of the Radixs Polygoni Multiflori, 17～23 parts of Rhizoma Alismatis, 22～28 parts of Pericarppium arachidis hypogaeaes, 27～33 parts of Semen Raphanis, 27～33 parts of Fructus Crataegis, 27～33 parts of the Radixs Astragali, 27～33 parts of Herba Epimedii;
Earlier above-mentioned each medicated powder is broken to graininess, inserts in the container, add the water that accounts for 3～4 times of above-mentioned each medicine cumulative volumes, 100 ℃ of water temperatures; Boiled 40 minutes, and filtered, take out clear liquid, spice adds the decocting in water that accounts for 2～3 times of above-mentioned each medicine volume total amounts again and takes out clear liquid after 40 minutes; Repeat once again, 3 decocting liquids are merged, freezing precipitation was got the Chinese herbal medicine extractum that supernatant concentration becomes water content 45-50% after 20 hours; Add ethanol and make extractum contain the alcohol amount to reach 70%, left standstill 24 hours, the leaching supernatant reclaims ethanol; Be concentrated into the extractum of relative density 1.30～1.32, use machine dry, dry thing is ground into fine powder, process and refine concentrated powder;
Compatibility is got Fructus Crataegi and Pericarppium arachidis hypogaeae again and is worn into 120～200 order fine powders for the second time, processes and gives birth to Fructus Crataegi and the peanut hull meal that extracts; Concentrate by per 1 jin of refinement of compatibility for the first time and to add 0.12 jin of Fructus Crataegi powder in the powder; 0.08 jin of peanut hull meal, the compatibility refinement concentrates adding Fructus Crataegi powder and peanut hull meal in the powder in the first time, behind the abundant mix homogeneously of mixed material medicine; Pack in No. 1 commercially available capsule, the weight of every capsules is 40mg.
2. detoxicating and hypolipemic capsule according to claim 1 is characterized in that: described wherein for the first time compatibility take off and state materials of weight proportions: rush down 5 parts on leaf, 5 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Radix Stephaniae Tetrandrae, 20 parts of the Radixs Polygoni Multiflori, 20 parts of Rhizoma Alismatis, 25 parts of Pericarppium arachidis hypogaeaes, 30 parts of Semen Raphanis, 30 parts of Fructus Crataegis, 30 parts of the Radixs Astragali, 30 parts of Herba Epimedii.
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| CN201110431300.1A CN102512548B (en) | 2011-03-04 | 2011-12-21 | Toxin-removing and fat-dispelling capsule |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201110051683.X | 2011-03-04 | ||
| CN201110051683XA CN102133308A (en) | 2011-03-04 | 2011-03-04 | Capsule for removing toxin and eliminating fat |
| CN201110431300.1A CN102512548B (en) | 2011-03-04 | 2011-12-21 | Toxin-removing and fat-dispelling capsule |
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| CN102512548B CN102512548B (en) | 2015-01-28 |
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| CN201110431300.1A Active CN102512548B (en) | 2011-03-04 | 2011-12-21 | Toxin-removing and fat-dispelling capsule |
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| CN102648971B (en) * | 2012-05-09 | 2014-07-02 | 宋斌斌 | Traditional Chinese medicinal composition for treating hyperlipidemia caused by internal obstruction of phlegm and dampness |
| CN103705595A (en) * | 2013-12-31 | 2014-04-09 | 邹天琼 | Capsule for cleaning and repairing heart vessels |
| CN103960671A (en) * | 2014-06-04 | 2014-08-06 | 孙喜灵 | Health-care food |
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| US6145039A (en) * | 1998-11-03 | 2000-11-07 | Intel Corporation | Method and apparatus for an improved interface between computer components |
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- 2011-12-21 CN CN201110431300.1A patent/CN102512548B/en active Active
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| CN1253802A (en) * | 1998-11-18 | 2000-05-24 | 陈江辉 | Body-building weight-reducing ointment and its preparation method |
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| CN1466977A (en) * | 2002-07-08 | 2004-01-14 | 邹天琼 | Kidney tonifying and bowel relaxing capsule |
| CN1586580A (en) * | 2004-07-07 | 2005-03-02 | 香港养春堂中药有限公司 | Pill for fat reducing |
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| CN102133308A (en) | 2011-07-27 |
| CN102512548B (en) | 2015-01-28 |
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Address after: 621000 room 31-901 of Changhong Century City, Mianyang, Mianyang, Sichuan Patentee after: Zou Tianqiong Address before: 100082 Beijing city Xicheng District Guang'an Road No. 6 outside the lotus 3-607 Patentee before: Zou Tianqiong |