CN102512175B - 用于测定分析物浓度的光学传感器 - Google Patents

用于测定分析物浓度的光学传感器 Download PDF

Info

Publication number
CN102512175B
CN102512175B CN201110391618.1A CN201110391618A CN102512175B CN 102512175 B CN102512175 B CN 102512175B CN 201110391618 A CN201110391618 A CN 201110391618A CN 102512175 B CN102512175 B CN 102512175B
Authority
CN
China
Prior art keywords
radiation
probe
optical
concentration
detector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201110391618.1A
Other languages
English (en)
Chinese (zh)
Other versions
CN102512175A (zh
Inventor
P·舒尔茨
A·阿莫索夫
N·伊兹瓦里娜
S·克拉维奇
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biosensory Inc
Original Assignee
Biosensory Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosensory Inc filed Critical Biosensory Inc
Publication of CN102512175A publication Critical patent/CN102512175A/zh
Application granted granted Critical
Publication of CN102512175B publication Critical patent/CN102512175B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/49Scattering, i.e. diffuse reflection within a body or fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1717Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • A61B5/7239Details of waveform analysis using differentiation including higher order derivatives
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1717Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
    • G01N2021/1725Modulation of properties by light, e.g. photoreflectance

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
CN201110391618.1A 2007-11-05 2008-10-31 用于测定分析物浓度的光学传感器 Expired - Fee Related CN102512175B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US196007P 2007-11-05 2007-11-05
US61/001960 2007-11-05
CN200880124606.9A CN101917899B (zh) 2007-11-05 2008-10-31 用于测定分析物浓度的光学传感器

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN200880124606.9A Division CN101917899B (zh) 2007-11-05 2008-10-31 用于测定分析物浓度的光学传感器

Publications (2)

Publication Number Publication Date
CN102512175A CN102512175A (zh) 2012-06-27
CN102512175B true CN102512175B (zh) 2015-12-02

Family

ID=40292516

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201110391618.1A Expired - Fee Related CN102512175B (zh) 2007-11-05 2008-10-31 用于测定分析物浓度的光学传感器
CN200880124606.9A Expired - Fee Related CN101917899B (zh) 2007-11-05 2008-10-31 用于测定分析物浓度的光学传感器

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN200880124606.9A Expired - Fee Related CN101917899B (zh) 2007-11-05 2008-10-31 用于测定分析物浓度的光学传感器

Country Status (9)

Country Link
US (1) US9915608B2 (https=)
EP (1) EP2207474B1 (https=)
JP (1) JP5646337B2 (https=)
CN (2) CN102512175B (https=)
AU (1) AU2008325237B2 (https=)
CA (1) CA2704789C (https=)
IL (1) IL205499A (https=)
TW (1) TWI468688B (https=)
WO (1) WO2009061367A2 (https=)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10413188B2 (en) * 2004-11-17 2019-09-17 Lawrence Livermore National Security, Llc Assessment of tissue or lesion depth using temporally resolved light scattering spectroscopy
US20090156932A1 (en) * 2007-12-13 2009-06-18 Board Of Trustees Of The University Of Arkansas Device and method for in vivo flow cytometry using the detection of photoacoustic waves
US9451884B2 (en) 2007-12-13 2016-09-27 Board Of Trustees Of The University Of Arkansas Device and method for in vivo detection of clots within circulatory vessels
EP2525194A1 (en) * 2011-05-16 2012-11-21 Knowles Electronics Asia PTE. Ltd. Optical sensor
JP5871958B2 (ja) * 2012-01-18 2016-03-01 キヤノン株式会社 被検体情報取得装置及び被検体情報取得方法
WO2014052449A1 (en) 2012-09-25 2014-04-03 The Board Of Trustees Of The University Of Arkansas Device and method for in vivo photoacoustic diagnosis and photothermal purging of infected blood
WO2014158988A1 (en) * 2013-03-14 2014-10-02 Profusa, Inc. Method and device for correcting optical signals
US10219729B2 (en) * 2013-06-06 2019-03-05 Profusa, Inc. Apparatus and methods for detecting optical signals from implanted sensors
US20150051473A1 (en) * 2013-08-15 2015-02-19 Covidien Lp Systems and methods for photoacoustic spectroscopy
KR102270798B1 (ko) * 2013-12-16 2021-06-30 삼성메디슨 주식회사 광음향 프로브 및 광음향 진단 장치
KR102143632B1 (ko) 2013-12-30 2020-08-11 삼성메디슨 주식회사 광음향 프로브 및 광음향 진단장치
CN104000599B (zh) * 2014-05-07 2016-06-01 辛勤 一种测量血糖浓度的方法及便携式设备
DE102014108424B3 (de) * 2014-06-16 2015-06-11 Johann Wolfgang Goethe-Universität Nicht-invasive Stoffanalyse
KR102244992B1 (ko) * 2014-10-17 2021-04-28 삼성전자주식회사 부하 전류 정보를 제공하는 전력관리 집적회로 및 그것을 포함하는 전자 장치
KR102390874B1 (ko) 2014-10-29 2022-04-26 삼성전자주식회사 혈당 측정기 및 그에 따른 혈당 측정 방법
CN104490403B (zh) * 2014-12-06 2016-08-17 深圳市贝沃德克生物技术研究院有限公司 基于光谱技术的无创血糖测量系统及其测量方法
WO2016107171A1 (zh) 2014-12-31 2016-07-07 歌尔声学股份有限公司 一种光电式脉搏信号测量方法及测量设备
CN104586370B (zh) * 2014-12-31 2018-01-30 歌尔股份有限公司 一种光电式脉搏信号测量方法、装置及测量设备
EP3240472B1 (en) 2014-12-31 2023-07-26 Bioventures, LLC. Devices and methods for fractionated photoacoustic flow cytometry
US10267956B2 (en) 2015-04-14 2019-04-23 California Institute Of Technology Multi-wavelength optical dielectric metasurfaces
FR3035716B1 (fr) * 2015-04-30 2019-06-21 Biomerieux Machine et procede pour la detection automatisee in vitro d'analytes mettant en oeuvre une decomposition spectrale chromatique d'une reponse optique
US9696259B2 (en) * 2015-08-18 2017-07-04 Lumasense Technologies Holdings, Inc. Optode sensor with integrated reference
WO2017034995A1 (en) * 2015-08-21 2017-03-02 California Institute Of Technology Planar diffractive device with matching diffraction spectrum
US11280728B2 (en) 2015-12-09 2022-03-22 Diamontech Ag Device and method for analyzing a material
KR102634764B1 (ko) 2015-12-09 2024-02-06 디아몬테크 아게 재료 분석을 위한 장치 및 방법
US10670782B2 (en) 2016-01-22 2020-06-02 California Institute Of Technology Dispersionless and dispersion-controlled optical dielectric metasurfaces
KR101746352B1 (ko) 2016-04-29 2017-06-12 다담마이크로 주식회사 광반사 측정법을 이용한 비침습식 혈당 측정 방법 및 장치
EP3315069A1 (en) 2016-10-25 2018-05-02 Roche Diabetes Care GmbH Method for determination of an analyte concentration in a body fluid and analyte concentration measurement device
GB2557311B (en) * 2016-12-06 2021-05-12 Rsp Systems As Analyte Detection apparatus and method of detecting an analyte
US10666321B2 (en) * 2016-12-29 2020-05-26 Tektronix, Inc. Sampling gate for broadband frequency reconstruction
US10488651B2 (en) 2017-04-10 2019-11-26 California Institute Of Technology Tunable elastic dielectric metasurface lenses
CA3061993C (en) * 2017-05-22 2025-04-01 Imec Vzw III-V/IV LASER SENSOR SYSTEM-CHIP FOR REAL-TIME MONITORING OF BLOOD COMPONENT CONCENTRATION LEVELS
CN107997769A (zh) * 2017-11-24 2018-05-08 天津大学 一种基于耳垂血液层的微波时延无创血糖浓度检测法
JP6845182B2 (ja) * 2018-05-01 2021-03-17 日本電信電話株式会社 成分濃度測定装置
AU2020331683B2 (en) * 2019-08-16 2025-08-14 Glucomat Gmbh Active miniaturized sensing system and method
CN115177244A (zh) * 2022-03-03 2022-10-14 北京理工大学 基于差分拉曼光谱的微型无创血糖检测系统
CN115227286B (zh) * 2022-06-28 2025-01-03 同济大学 超声探头自适应引导穿刺的装置、方法及采血箱

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4573761A (en) * 1983-09-14 1986-03-04 The Dow Chemical Company Fiber-optic probe for sensitive Raman analysis
US6097975A (en) * 1998-05-13 2000-08-01 Biosensor, Inc. Apparatus and method for noninvasive glucose measurement
US20050010090A1 (en) * 2002-03-08 2005-01-13 George Acosta Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5119815A (en) * 1988-12-21 1992-06-09 Nim, Incorporated Apparatus for determining the concentration of a tissue pigment of known absorbance, in vivo, using the decay characteristics of scintered electromagnetic radiation
US5657754A (en) 1995-07-10 1997-08-19 Rosencwaig; Allan Apparatus for non-invasive analyses of biological compounds
JP4212007B2 (ja) 1996-11-26 2009-01-21 パナソニック電工株式会社 血液成分濃度の分析装置
JP4120684B2 (ja) * 1996-11-26 2008-07-16 松下電工株式会社 分光分析法による血液成分濃度の分析装置
US5941821A (en) * 1997-11-25 1999-08-24 Trw Inc. Method and apparatus for noninvasive measurement of blood glucose by photoacoustics
AU2001259435A1 (en) * 2000-05-03 2001-11-12 Stephen T Flock Optical imaging of subsurface anatomical structures and biomolecules
US6635491B1 (en) * 2000-07-28 2003-10-21 Abbott Labortories Method for non-invasively determining the concentration of an analyte by compensating for the effect of tissue hydration
US6675030B2 (en) * 2000-08-21 2004-01-06 Euro-Celtique, S.A. Near infrared blood glucose monitoring system
JP3590047B1 (ja) 2003-09-24 2004-11-17 株式会社日立製作所 光学測定装置及びそれを用いた血糖値測定装置
US20050277872A1 (en) * 2004-05-24 2005-12-15 Colby John E Jr Apparatus and method for mobile medical services
US8346347B2 (en) * 2005-09-15 2013-01-01 Palomar Medical Technologies, Inc. Skin optical characterization device

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4573761A (en) * 1983-09-14 1986-03-04 The Dow Chemical Company Fiber-optic probe for sensitive Raman analysis
US6097975A (en) * 1998-05-13 2000-08-01 Biosensor, Inc. Apparatus and method for noninvasive glucose measurement
US20050010090A1 (en) * 2002-03-08 2005-01-13 George Acosta Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy

Also Published As

Publication number Publication date
WO2009061367A2 (en) 2009-05-14
JP5646337B2 (ja) 2014-12-24
HK1172229A1 (zh) 2013-04-19
WO2009061367A3 (en) 2009-08-13
CN101917899A (zh) 2010-12-15
CA2704789C (en) 2018-07-24
TW200935054A (en) 2009-08-16
HK1151958A1 (en) 2012-02-17
EP2207474B1 (en) 2018-08-22
IL205499A0 (en) 2010-12-30
US20110105867A1 (en) 2011-05-05
AU2008325237A1 (en) 2009-05-14
CN102512175A (zh) 2012-06-27
JP2011502627A (ja) 2011-01-27
TWI468688B (zh) 2015-01-11
US9915608B2 (en) 2018-03-13
IL205499A (en) 2013-03-24
AU2008325237B2 (en) 2014-05-01
EP2207474A2 (en) 2010-07-21
CN101917899B (zh) 2014-03-12
CA2704789A1 (en) 2009-05-14

Similar Documents

Publication Publication Date Title
CN102512175B (zh) 用于测定分析物浓度的光学传感器
JP5541662B2 (ja) 被検体情報取得装置およびその制御方法
EP2335579B1 (en) Component concentration measuring device and method of controlling component concentration measuring device
JP5235586B2 (ja) 生体情報処理装置及び生体情報処理方法
CN101557752B (zh) 脉动血中的葡萄糖浓度测量方法
US6403944B1 (en) System for measuring a biological parameter by means of photoacoustic interaction
CN101346097B (zh) 血糖浓度的无创测量系统
CN104706363B (zh) 一种复合型光声无损动态血糖检测仪
JP2006516207A (ja) 光音響分析方法及び装置
US20110125004A1 (en) Analysis by photo acoustic displacement and interferometryl
WO2011152747A1 (en) Photoacoustic material analysis
JP2011092631A (ja) 生体情報処理装置及び生体情報処理方法
JP2008045938A (ja) 被検体組織内の被分析物の濃度測定のための光音響分析方法及び光音響分析装置
RU2435514C1 (ru) Способ фотоакустического анализа материалов и устройство для его реализации
JP2009232876A (ja) 生体検査用プローブ及び生体検査装置
EP4144292B1 (en) Process and analyte monitor for estimating a quantity in mathematical relationship with an analyte concentration level in a target
JP6080004B2 (ja) パラメータ計測装置、パラメータ計測方法、及びプログラム
HK1172229B (en) An optical sensor for determining the concentration of an analyte
HK1151958B (en) Optical sensor for determining the concentration of an analyte
US20230293055A1 (en) Smart-Tooth Blood Glucose Measurement Device
EP4505940B1 (en) Device and method for detecting an analyte in tissue using an adjustable irradiation position

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1172229

Country of ref document: HK

C14 Grant of patent or utility model
GR01 Patent grant
REG Reference to a national code

Ref country code: HK

Ref legal event code: GR

Ref document number: 1172229

Country of ref document: HK

CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20151202

Termination date: 20181031

CF01 Termination of patent right due to non-payment of annual fee