CN102511711A - Healthcare food capsule and preparation method for same - Google Patents
Healthcare food capsule and preparation method for same Download PDFInfo
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- CN102511711A CN102511711A CN2011104201171A CN201110420117A CN102511711A CN 102511711 A CN102511711 A CN 102511711A CN 2011104201171 A CN2011104201171 A CN 2011104201171A CN 201110420117 A CN201110420117 A CN 201110420117A CN 102511711 A CN102511711 A CN 102511711A
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Abstract
The invention provides a healthcare food capsule, composed of a content and a capsule skin, wherein the content is a mixture prepared by raw materials in parts by weight: 15-25 parts of chitosan powder, 5-15 parts of kudzuvine root extract, 1-5 parts of semen cassiae extract, 8-18 parts of hawthorn extract, 15-25 parts of corn oil and 40-55 parts of tea seed oil. The capsule skin is prepared by edible gelatine, glycerol and purified water in a weight ratio of 1: 1: 0.5. The content is obtained by crushing raw materials, proportioning, mixing, grinding and degassing. The capsule skin is prepared by using edible gelatine, glycerol and purified water as capsule skin raw materials, mixing, dissolving gelatine and heating to obtain gelatine solution, performing pelleting, shaping, drying, washing, lamp inspection, packaging and final inspection on the content and the gelatine solution of the capsule via an automatic machine. The processing method for the product is reasonable and practical. The healthcare food capsule provided by the invention has the functions of reducing blood fats, reducing blood pressure and reducing blood sugar, as well as is easy to absorb by human body without any toxic and side effect, and capable of being taken for a long time.
Description
Technical field
The present invention relates to a kind of health-care edible capsule, be specifically related to a kind of health-care edible capsule, the invention still further relates to the preparation method of this food capsule with reducing blood lipid, hypotensive and effect of lowering blood sugar.
Background technology
Along with the change of China's rapid economy development people diet structure and habits and customs, cardiovascular and cerebrovascular diseases such as high fat of blood, hyperglycaemia, hypertension, coronary heart disease, headstroke have become " the No.1 killer " of China's people's health.
According to " Chinese health statistics summary " data in 2010, cardiovascular and cerebrovascular disease caused death toll to surpass 40% of the total death toll in the whole nation.The incidence of China the elderly cardiovascular and cerebrovascular disease: high fat of blood: existing patient 2.1 hundred million, year increases 5,000,000; High blood is sticking: existing patient 1.5 hundred million, and year increases 4,000,000; Hypertension: existing patient 1.7 hundred million, year increases 4,000,000; Hyperglycaemia, diabetes patient 9,000 ten thousand, year increases 3,500,000; Per 6 philtrums in the whole nation just have a hyperlipemic patients; Per 11 philtrums just have a hyperpietic.Hypertension can cause cerebrovascular explosion, angina pectoris, cerebral thrombus, high lithemia, impaired, the erectile dysfunction diseases such as (ED) of kidney.Whole world hypertension has 500,000,000.China's incidence of disease reaches 14%; The cardiovascular and cerebrovascular diseases such as apoplexy that hypertension causes become the dead head of China town dweller because of.
High fat of blood is meant that the concentration of lipid compositions such as plasma cholesterol, triglycerides, total fat surpasses arm's length standard.The main harm of hyperlipemia is to cause atherosclerotic, and then causes numerous relevant diseases, and wherein modal a kind of mortality disease is exactly a coronary heart disease.
In addition, hyperlipemia also is an important risk factor that promotes hypertension, IGT, diabetes.Hyperlipemia also can cause fatty liver, cirrhosis, cholelithiasis, pancreatitis, fundus hemorrhage, blind, peripheral vascular disease, limping, hyperuricemia.Tendon shape, nodositas, palm plane and eye socket xanthoma, embryotoxon etc. on every side also can appear in some primary and familial hyperlipemia.This disease to the infringement of health be concealment, gradually, carrying out property and general.Its direct infringement is the acceleration systemic atherosclerosis.The renal failure that artery sclerosis causes etc., all closely related with hyperlipemia.A large amount of research datas show that hyperlipemia is cerebral apoplexy, coronary heart disease, myocardial infarction, cardiac sudden death is independent and important risk.
In view of this; The present invention provides a kind of health-care edible capsule with remarkable reducing blood lipid, hypotensive and effect of lowering blood sugar; Its main effect raw material is that (shitosan is the product of chitin deacetylase base to shitosan; The chitin deacetylase degree that the present invention adopts reaches more than 85%) and tea seed oil, this case produces thus.
Summary of the invention
The purpose of this invention is to provide a kind of health-care edible capsule with significant reducing blood lipid, hypotensive and effect of lowering blood sugar, this capsule has human body and is prone to the characteristic that absorbs, and is without any side effects, can take for a long time.Another object of the present invention provides a kind of preparation method of above-mentioned health-care edible capsule, and this method is practical.
A kind of health-care edible capsule, it is made up of content and rubber; Content is the mixture of being processed by the following weight proportion raw material:
Chitosan powder 15-25
Kudzu root extract 5-15
Cassia seed extract 1-5
Haw thorn extract 8-18
Corn oil 15-25
Tea seed oil 40-55.
Kudzu root extract adopts following method to extract and obtains: root of kudzu vine water after cleaning, pulverizing extracts under 45 ℃ of-100 ℃ of temperature; Concentrating then makes the proportion of solution reach 1.35-1.40; Add depositing in water again and fell 24-48 hour, make the proportion of solution reach 1.1-1.2; Draw up that clear liquid concentrates, spray-drying, after thermostatic constant wet chamber's condition is descended 100 mesh sieves, obtained kudzu root extract.
Cassia seed extract adopts following method to extract and obtains: cassia seed water after cleaning, pulverizing extracts under 45 ℃ of-100 ℃ of temperature; Concentrating then makes the proportion of solution reach 1.35-1.40; Add depositing in water again and fell 24-48 hour, make the proportion of solution reach 1.1-1.2; Draw up that clear liquid concentrates, spray-drying, after thermostatic constant wet chamber's condition is descended 100 mesh sieves, obtained cassia seed extract.
Haw thorn extract adopts following method to extract and obtains: hawthorn water after cleaning, pulverizing extracts under 45 ℃ of-100 ℃ of temperature; Concentrating then makes the proportion of solution reach 1.35-1.40; Add depositing in water again and fell 24-48 hour, make the proportion of solution reach 1.1-1.2; Draw up that clear liquid concentrates, spray-drying, after thermostatic constant wet chamber's condition is descended 100 mesh sieves, obtained haw thorn extract.
Above-mentioned rubber is by the ratio preparation by weight 1:1:0.5 of edible gelatin, glycerine and purified water.
Contain shitosan in the health-care edible capsule raw material of the present invention.Shitosan is the product of chitin N-deacetylation; The shitosan difficulty is digested and assimilated by the human intestines and stomach, and after the people took in them in the body, they can generate complex compound with lipoid substances such as the triglycerides that is equivalent to the sole mass manyfold, aliphatic acid, bile acid and cholesterol; This complex compound is not by the hydrochloric acid in gastric juice hydrolysis; Do not absorbed, thereby hinder this type of absorption of human body material, make it to wear intestines and cross and excrete by digestive system.Therefore, the shitosan class can lipopenicillinase, reduces the food heat.
Under the effect of shitosan, health-care edible capsule of the present invention has following effect:
One, reducing blood lipid:
It is one of principal element that causes cardiovascular and cerebrovascular disease that blood fat raises.Shitosan is the polymer of the unique positively charged basic group of nature, is prone to combine with electronegative bile acid and promote it to excrete, and therefore, can hinder the absorption of cholesterol at enteron aisle, has effect for reducing blood fat.Shitosan can also reduce low-density lipoprotein (LDL), and increasing high density lipoprotein (HDL) has dual regulation;
Two, hypotensive:
Shitosan be positively charged cation radical because of, can combine with the chlorion in the salt, excrete with ight soil, reduce the absorption of chlorion.Or the unimolecule shitosan combines with chlorion, reduces the chlorine ion concentration in the blood sugar, makes that ACE (ACE) is active to be reduced, and causes hypertensin 11 to form and reduces, and bradykinin increases in making, and vasorelaxation action strengthens, blood pressure drops;
Three, hypoglycemic:
It is acid that diabetic's body fluid often is; Sensitiveness to insulin descends: shitosan has the effect of the body fluid of adjusting pH value; Can make gastrointestinal pH value 0.5 unit of alcaliotropism side shifting slightly, help strengthening the sensitiveness and the utilization rate of insulin, thereby improve glycometabolism, reduction blood sugar.Shitosan also has the effect of regulating internal system, can promote pancreas islet B cellular-restoring function, makes the amount of insulin secretion trend normal, keeps the blood sugar eubolism.Shitosan also has certain treatment and prevention effect to diabetic complication.In addition, shitosan also has body immunity; Antitumor; Strengthen liver function; Effects such as protection intestines and stomach.
Another effect raw material tea seed oil among the present invention is that the seed that produces after the tealeaves tree blooms squeezes and the next a kind of novel edible oil that is called as " liquid golden ".Tea seed oil is rich in unrighted acid, and is long-term edible to angiocardiopathy, reduces cholesterol in serum, hypertension, and cardiovascular and cerebrovascular, obesity has obvious curative effects.Tea seed oil can also improve the metabolism of organism and strengthen internal system.It also has good effect in anti-cancer, radiation proof, aspect anti-ageing.Still there is not the tea seed oil of use in the prior art as health products active ingredient.The present invention aims to provide a kind of health-care edible capsule that contains the significant reducing blood lipid of having of tea seed oil, hypotensive and effect of lowering blood sugar.
The main effect raw material of health-care edible capsule of the present invention is shitosan (shitosan is the product of chitin deacetylase base, and we reach 85% by the chitin deacetylase degree of usefulness) and tea seed oil.Shitosan of the present invention combines tea seed oil and other raw material, reducing blood lipid, hypotensive and hypoglycemic aspect effect more remarkable.
In addition, also contain the root of kudzu vine, cassia seed, hawthorn and corn oil in the health food of the present invention, they also have step-down, and lipopenicillinase is anti-oxidant, health-care effects such as enhance immunity power.
Health-care edible capsule of the present invention fully takes into account medication food dual-use materials and carries out prescription when selecting above-mentioned raw materials for use, and it is theoretical to have met the health care of advocating " back to nature " and " integration of drinking and medicinal herbs " now.
The method for preparing health-caring capsule of the present invention is made up of following steps successively:
A) pulverize: chitosan powder is become 100-200 purpose fine powder with the superfine powder apparatus processing, sterilized 30 minutes down at 115 ℃;
B) prepare burden, mix: shitosan fine powder weight portion 15-25, kudzu root extract weight portion 5-15, cassia seed extract weight portion 1-5 and haw thorn extract weight portion 8-18 are mixed obtaining powder mixture in clean area; Add corn oil weight portion 15-25, tea seed oil weight portion 40-55 mixing again, mixture is added in the mixer evenly mix;
C) grind, outgas: above-mentioned mixture after being mixed is sent into fine grinding in the colloid mill, insert the vacuum material-compound tank then and slough the gas in the material, obtain capsule 's content;
D) change glue: gelatin, glycerine and purified water are changed glue in the ratio adding jacketed pan of 1:1:0.5;
E) pill: will change glue and capsule 's content batching behind the glue, and be pressed into soft capsule through pellet press, wherein the pill temperature is 50-80 ℃.Pill temperature with best pill effect is 60 ℃.
In the capsule preparation method thereof of the present invention, capsule 's content is through pulverizing, and batching is mixed, and grinds, and the degassing obtains.Capsule rubber is the rubber raw material with edible gelatin, glycerine, purified water, through mixing, change glue, intensification acquisition glue, again capsule 's content and glue is carried out pelleting, typing, drying through automated machine, washes ball, the lamp inspection, and packing is processed after examining eventually.The processing method of capsule is reasonable, practicality good.
Health product active principle prescription of the present invention is oily, coats active principle of the present invention with capsule and can reach best result of use.Dosage form selection soft capsule of the present invention be because: soft capsule is through totally enclosed form, and content and air is isolated, prevents the oxidation of content active ingredient and loses effectiveness or pollution; Cover the poor taste of raw material simultaneously, the active ingredient of goods exists with liquid condition, and dissolubility is good; Be prone to absorb, enhanced stability, curative effect are able to guarantee; Inside can be not infested, is easy to carry and takes.
Health-caring capsule of the present invention has reducing blood lipid, hypotensive and hypoglycemic booster action, and is easy to absorption of human body, and is without any side effects, can take for a long time.
The specific embodiment
Embodiment 1:
At first prepare kudzu root extract, cassia seed extract and haw thorn extract.
Above-mentioned each extract is to soak 2 hours (45 ℃ of soaking temperatures) with above-mentioned each raw material then through cleaning, pulverizing; Water extracts three times, and (10 times of decoctings boiled 2 hours for the first time; 8 times of decoctings boiled 1.5 hours for the second time; 6 times of decoctings boiled temperature 45-100 ℃ 1 hour for the third time), then concentrate (proportion d=1.35-1.40), again add the pure water sedimentation 24-48 hour, draw up clear liquid and concentrate (proportion d=1.1-1.2), filtrating spray-drying, after 100 mesh sieves are crossed by thermostatic constant wet chamber, obtain above-mentioned each extract.
Take by weighing raw material (gram) by following proportioning again:
1. shitosan 15, kudzu root extract 5, cassia seed extract 1, haw thorn extract 8, corn oil 15, tea seed oil 40;
2. shitosan 25, kudzu root extract 15, cassia seed extract 5, haw thorn extract 18, corn oil 25, tea seed oil 55;
3. shitosan 20, kudzu root extract 10, cassia seed extract 3, haw thorn extract 10, corn oil 20, tea seed oil 50.
The allocation ratio of edible gelatin, glycerine, purified water is: 1:1:0.5.Capsule is processed every ball 0.5g.
Production method is following:
1) pulverize: chitosan powder is become 100-200 purpose fine powder with the superfine powder apparatus processing, sterilize under the 115 degree conditions 30 minutes subsequent use; (shitosan among the embodiment derives from chitin, and shitosan is the product of chitin deacetylase base, and the chitin deacetylase degree reaches 85%.）
2) batching, mixing: get shitosan fine powder, kudzu root extract, cassia seed extract and haw thorn extract, above-mentioned material is mixed obtaining powder mixture in 100,000 grades of clean areas, add corn oil, tea seed oil mixing again; Mixture is put into mixer evenly to mix;
3) grind, outgas: above-mentioned mixture after being mixed is sent into fine grinding in the colloid mill, insert the vacuum material-compound tank then and slough the gas in the material, can obtain capsule 's content;
4) change glue: gelatin, glycerine, purified water are changed glue according to the above ratio in jacketed pan;
5) pill: glue and capsule 's content batching are extruded qualified soft capsule through pellet press, and the pill temperature is 50-80 ℃ (60 ℃ of the bests);
6) setting: with capsule shaping;
7) wash ball: with soft capsule with edible alcohol flush away surface oil;
8) drying: at dry rotating cage inner drying, the temperature of dry rotating cage is 40-60 ℃ (40 ℃ of the bests) with capsule;
9) lamp inspection: select the conformality ball, remove non-conformality ball;
10) with select capsule packing;
11) final inspection: the storehouse always checks in.
Embodiment 2:
We have also measured and have tested the relevant data that the patient takes the health-caring capsule of the present invention front and back body's immunity of normal dose, and the result is following:
Use-case 1:
Mr. Chen 62 years old, often has headache and dizzy, uncomfortable in chest breathing hard, irritated insomnia over 7 years; Soreness and weakness of waist and knees, constipation phenomenon, blood pressure 142/95mmHg, cholesterol 263ng/dl, low-density lipoprotein 142ng/dl; Three acid glycerol 65ng/dl, glucose in urine ++, blood sugar 259ng/dl adheres to taking Western medicine.Take this capsule after four months, blood pressure 121/86mmHg, cholesterol 245ng/dl, low-density lipoprotein 123.5ng/dl; Three acid glycerol 61ng/dl, glucose in urine, blood sugar recovery are normal, headache and dizzy; Uncomfortable in chest breathing hard, irritated insomnia, soreness and weakness of waist and knees, constipation phenomenon are obviously improved.
Use-case 2:
Mr. Huang, 57 years old, finding before 6 years had hypertension, and blood pressure 157/105mmHg adheres to taking the Western medicine step-down; Headache and dizzy is often arranged, dizzy tinnitus, irritated insomnia, soreness and weakness of waist and knees symptom; Take this capsule and reduce the Western medicine consumption, do not need after three months to take Western medicine again, blood pressure is reduced to 127/88mmHg, and no headache is dizzy; Dizzy tinnitus, irritated insomnia, symptoms such as soreness and weakness of waist and knees, heart rate no significant change before and after administration.
Use-case 3:
Mr. Fan, 65 years old, found weakness of limbs, glucose in urine before 8 years ++, blood sugar 267ng/dl adheres to taking Western medicine.Take this capsule and reduce the Western medicine consumption, behind the one and a half months, glucose in urine+, blood sugar 159ng/dl, physical recovery is good.
Use-case 4:
Mrs Fang 59 years old, normal uncomfortable in chestly breathes hard, irritated insomnia, constipation blood pressure 135/102mmHg, cholesterol 285ng/dl, low-density lipoprotein 137.5ng/dl, three acid glycerol 92ng/dl.Take this capsule after two months, blood pressure 117/85mmHg, cholesterol 246ng/dl, low-density lipoprotein 119.7ng/dl, three acid glycerol 69ng/dl noly uncomfortable in chestly breathe hard, irritated insomnia, and the constipation phenomenon alleviates greatly.
Above embodiment only in order to the explanation the present invention and and unrestricted technical scheme described in the invention; Therefore; Although this specification has carried out detailed explanation with reference to each above-mentioned embodiment to the present invention; But those of ordinary skill in the art should be appreciated that still and can make amendment or be equal to replacement the present invention; And all do not break away from the technical scheme and the improvement thereof of spirit of the present invention, and it all should be encompassed in the claim scope of the present invention.
Claims (4)
1. health-care edible capsule, it is made up of content and rubber;
It is characterized in that content is the mixture of being processed by the following weight parts proportion raw material:
Chitosan powder 15-25
Kudzu root extract 5-15
Cassia seed extract 1-5
Haw thorn extract 8-18
Corn oil 15-25
Tea seed oil 40-55;
Said kudzu root extract adopts following method to extract and obtains: root of kudzu vine water after cleaning, pulverizing extracts under 45 ℃ of-100 ℃ of temperature; Concentrating then makes the proportion of solution reach 1.35-1.40; Add depositing in water again and fell 24-48 hour, make the proportion of solution reach 1.1-1.2; Draw up that clear liquid concentrates, spray-drying, after thermostatic constant wet chamber's condition is descended 100 mesh sieves, obtained kudzu root extract;
Said cassia seed extract adopts following method to extract and obtains: cassia seed water after cleaning, pulverizing extracts under 45 ℃ of-100 ℃ of temperature; Concentrating then makes the proportion of solution reach 1.35-1.40; Add depositing in water again and fell 24-48 hour, make the proportion of solution reach 1.1-1.2; Draw up that clear liquid concentrates, spray-drying, after thermostatic constant wet chamber's condition is descended 100 mesh sieves, obtained cassia seed extract;
Said haw thorn extract adopts following method to extract and obtains: hawthorn water after cleaning, pulverizing extracts under 45 ℃ of-100 ℃ of temperature; Concentrating then makes the proportion of solution reach 1.35-1.40; Add depositing in water again and fell 24-48 hour, make the proportion of solution reach 1.1-1.2; Draw up that clear liquid concentrates, spray-drying, after thermostatic constant wet chamber's condition is descended 100 mesh sieves, obtained haw thorn extract.
2. health-care edible capsule according to claim 1 is characterized in that: said rubber is by the ratio preparation by weight 1:1:0.5 of edible gelatin, glycerine and purified water.
3. the preparation method of the described health-care edible capsule of claim 2 is characterized in that this method comprises the steps:
A) pulverize: chitosan powder is become 100-200 purpose fine powder with the superfine powder apparatus processing, sterilized 30 minutes down at 115 ℃;
B) prepare burden, mix: shitosan fine powder weight portion 15-25, kudzu root extract weight portion 5-15, cassia seed extract weight portion 1-5 and haw thorn extract weight portion 8-18 are mixed obtaining powder mixture in clean area; Add corn oil weight portion 15-25, tea seed oil weight portion 40-55 mixing again, mixture is added in the mixer evenly mix;
C) grind, outgas: above-mentioned mixture after being mixed is sent into fine grinding in the colloid mill, insert the vacuum material-compound tank then and slough the gas in the material, obtain capsule 's content;
D) change glue: gelatin, glycerine and purified water are changed glue in the ratio adding jacketed pan of 1:1:0.5;
E) pill: will change glue and capsule 's content batching behind the glue, and be pressed into soft capsule through pellet press, wherein the pill temperature is 50-80 ℃.
4. the preparation method of health-care edible capsule according to claim 3, it is characterized in that: in the step e), said pill temperature is 60 ℃.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103330119A (en) * | 2013-06-07 | 2013-10-02 | 青岛银龄美海洋生物科技有限公司 | Health-care food for accessorily reducing blood fat |
| CN104886435A (en) * | 2015-06-16 | 2015-09-09 | 青岛浩大海洋保健食品有限公司 | Chitosan-containing health care capsule with blood lipid regulation efficacy |
| CN108041589A (en) * | 2017-12-11 | 2018-05-18 | 江西省三抗保健品有限公司 | A kind of soft capsule of strengthen immunity auxiliary reducing blood lipid and preparation method thereof |
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- 2011-12-15 CN CN 201110420117 patent/CN102511711B/en active Active
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103330119A (en) * | 2013-06-07 | 2013-10-02 | 青岛银龄美海洋生物科技有限公司 | Health-care food for accessorily reducing blood fat |
| CN104886435A (en) * | 2015-06-16 | 2015-09-09 | 青岛浩大海洋保健食品有限公司 | Chitosan-containing health care capsule with blood lipid regulation efficacy |
| CN108041589A (en) * | 2017-12-11 | 2018-05-18 | 江西省三抗保健品有限公司 | A kind of soft capsule of strengthen immunity auxiliary reducing blood lipid and preparation method thereof |
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| CN102511711B (en) | 2013-08-14 |
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