CN102500508B - Intelligent specimen developer filling device - Google Patents

Intelligent specimen developer filling device Download PDF

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Publication number
CN102500508B
CN102500508B CN 201110315545 CN201110315545A CN102500508B CN 102500508 B CN102500508 B CN 102500508B CN 201110315545 CN201110315545 CN 201110315545 CN 201110315545 A CN201110315545 A CN 201110315545A CN 102500508 B CN102500508 B CN 102500508B
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CN
China
Prior art keywords
cylinder
stirring motor
filling
push
piston rod
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN 201110315545
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Chinese (zh)
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CN102500508A (en
Inventor
刘云龙
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DALIAN HOFFEN BIO-TECHNIQUE Co Ltd
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DALIAN HOFFEN BIO-TECHNIQUE Co Ltd
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Priority to CN 201110315545 priority Critical patent/CN102500508B/en
Publication of CN102500508A publication Critical patent/CN102500508A/en
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Publication of CN102500508B publication Critical patent/CN102500508B/en
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Abstract

The invention provides an intelligent specimen developer filling device, which is mainly characterized by that a bracket is provided with raw material buckets and outlet ends of material outlet pipes of these raw material buckets are arranged on an opening of a filling vat. The lower end of the filling vat and the bottom of a pulling/pushing sliding disc are provided with openings. A horizontal sliding channel which is fixed on the bracket is arranged under the sliding disc. A piston rod of a pulling/pushing cylinder is connected with a sliding disc of the filling vat. The upper end of the piston rod of a stirring motor elevating cylinder is connected with one end of a coupling rod, and the other end of the coupling rod is connected with a sliding plate of the stirring motor. The motor sliding plate fixed with a motor base is arranged on a dovetail groove sliding channel, and the sliding channel is fixed on the bracket. A stirring impeller is arranged at the lower end of a spindle of the stirring motor. Furthermore a squeezing cylinder is provided, above which an air depressurizing valve is arranged, and a squeezing disc is arranged at the free end of the piston rod under the squeezing cylinder. According to the invention, the specimen developer can be filled mechanically, and therefore the cost is reduced and the work efficiency is improved. Most importantly, the quality of specimen making is improved.

Description

Intelligent sample developer perfusion equipment
Technical field
The present invention relates to a kind of liquid state colloid filling apparatus, is the equipment that injects the liquid state colloid developer in the blood vessel of biological sample.
Background technology
Original work of injecting developer in the blood vessel of biological sample is to adopt manual manipulation method, and its operating process is loaded down with trivial details, and the material waste is more, inefficiency.In order to improve charging efficiency, the present method that adopts air pressure directly to pour into, though its efficient improves a lot, but still have many weak points: 1, do not break away from the use manpower, the weakness that the preparation time is long, 2, several raw material mixed proportion is not accurate, 3, careless manipulation, gas easily enters in the perfusion blood vessel, causes sample to damage.
Summary of the invention
The object of the present invention is to provide the intelligent sample developer perfusion equipment that a kind of high efficiency, pouring quality are good, save manpower and material.
The present invention mainly includes: support, Raw material pail, filling cylinder, slide rail, agitator, push-and-pull cylinder, extruding disk, extruding cylinder, stirring motor cylinder and electric cabinet.
Wherein, support is the framework that shape constitutes, and which is provided with the Raw material pail of several each components of splendid attire developer,
The upper shed of these Raw material pails is charging aperture, and under shed is discharging opening, which is provided with the magnetic valve of control discharging, and this magnetic valve links to each other with discharge nozzle one end, and the port of export of this discharge nozzle is positioned at the filling cylinder above the opening in home position.This filling cylinder is the cylinder of lower end closed, and its bottom is fixed on the flat push-and-pull sliding plate, is provided with the horizontal slideway that is fixed on the support below the sliding plate.Filling cylinder and corresponding slideway bottom are provided with outlet, which is provided with anti-backflow individual event valve, and this check valve links to each other with output sebific duct one end, and this output sebific duct other end can be enclosed within on the injection head, annotates in order to insert the sample blood vessel.Be preferably in sliding plate and filling cylinder bottom portion also is provided with anti-negative one-way valve.Support at above-mentioned slide rail one end is provided with the axis push-and-pull cylinder parallel with slide rail, and the piston rod of this push-and-pull cylinder links to each other with filling cylinder sliding plate, and the flexible filling cylinder that orders about by this push-and-pull cylinder piston rod is in the slide rail movement.Being provided with an axis near the support corresponding with the shortest position of push-and-pull cylinder piston rod contraction is vertical stirring motor lift cylinder, the piston rod upper end of this cylinder links to each other with coupling bar one end of level, the coupling bar other end of this level links to each other with the stirring motor slide plate, the motor slide plate that motor base should fixedly be arranged, its swallow-tail form slide block is positioned on the vertical dovetail slideway, and this slideway is fixed on the support.Vertical stirring motor rotating shaft lower end is provided with the impeller corresponding with the cylinder of annotating, and this impeller can stretch in the filling cylinder.Be vertical extruding cylinder with being provided with an axis filling cylinder is shifted onto the corresponding support of highest distance position by the push-and-pull cylinder above in addition, this is provided with the gas balance pressure detection switch above extruding cylinder, following piston rod free end is provided with perpendicular continuous disc extruding disk, and its diameter is slightly smaller than the filling cylinder diameter.Above-mentioned push-and-pull cylinder, extruding cylinder and stirring motor lift cylinder, all be equipped with two separately at two ends and be used for the magnetic switch of control automatically, and and the wiring of the magnetic valve wiring of Raw material pail and stirring motor constitute relay logic circuit, in the rack-mount electric cabinet.
This machine is when starting working, and the push-and-pull cylinder is to be in the maximum collapse position.Under the control of circuit, the magnetic valve of three Raw material pails is opened simultaneously, and they just inject the colloidal liquid of the difference batching have color respectively in the filling cylinder, as shown in Figure 5.Because the dosage that technology has determined every kind of raw material to annotate is different, so the time length that each magnetic valve is opened is controlled by circuit.Behind last closed electromagnetic valve, stirring motor lift cylinder action is shunk the piston rod of this cylinder, so the stirring motor impeller moves downward the position of setting to the cylinder, stirring motor begins rotation and stirs then, as shown in Figure 6.After having reached the time of setting, motor stops operating.The piston rod of stirring motor cylinder gos up then, orders about stirring motor and rises, and namely stops after the stirring motor impeller is higher than the filling cylinder, as shown in Figure 7.The push-and-pull cylinder is started working then, i.e. piston rod elongation, and the cylinder of will annotating is pushed forward under the extruding disk, as shown in Figure 8.Extruding disk stretches into extruding downwards in the cylinder (squeeze pressure is by the control of gas balance pressure detection switch) as shown in Figure 9 under the drive of extruding cylinder piston rod.After extruding disk was finished extrusion process, cylinder piston upwards rose, and extruding disk breaks away from the filling cylinder, as shown in figure 10.Be withdrawn into the home position by the push-and-pull cylinder cylinder of will annotating at last, as shown in figure 11, so just finished a filling cycle.
The present invention compared with prior art has following advantage: can make the perfusion of sample developer realize automation, save manpower and material, reduce cost, reduce the man-hour of pouring into, improved operating efficiency; Also eliminate artificial unfavorable factor, improved the quality of preparation of specimen widely.
Description of drawings:
Fig. 1 is the three-dimensional simplified schematic diagram of the present invention.
Fig. 2 is that the master of removal support of the present invention looks simplified schematic diagram.
Fig. 3 is the side view of dotted portion among Fig. 1.
Fig. 4 is circuit diagram of the present invention.
Fig. 5 is that the master of job step one of the present invention looks schematic diagram.
Fig. 6 is that the master of job step two of the present invention looks schematic diagram.
Fig. 7 is that the master of job step three of the present invention looks schematic diagram.
Fig. 8 is that the master of job step four of the present invention looks schematic diagram.
Fig. 9 is that the master of job step five of the present invention looks schematic diagram.
Figure 10 is that the master of job step six of the present invention looks schematic diagram.
Figure 11 is that the master of job step seven of the present invention looks schematic diagram.
Among the figure: 1-pushes cylinder, 2-equalizing pressure sense switch, the 3-stirring motor, 4-stirring motor lifter slide, the 5-Raw material pail, the 6-magnetic valve, the 7-electric cabinet, 8-push-and-pull cylinder, 9-prevents negative one-way valve, 10-anti-return check valve, 11-exports sebific duct, 12-push-and-pull slideway, 13-push-and-pull sliding plate, the 14-cylinder of annotating, the 15-extruding disk, 16-magnetic switch ck3-2,17--magnetic switch ck3-1,18-stirring motor lift cylinder, 19--magnetic switch ck2-2,20--magnetic switch ck2-1,21--magnetic switch ck1-1,22--magnetic switch ck1-2,23-stirring motor impeller, the 24-support.
The specific embodimentIn the schematic diagram of intelligent sample developer perfusion equipment illustrated in figures 1 and 2, support is the framework that shape constitutes, which is provided with the Raw material pail of 3 each components of splendid attire developer, the upper shed of these Raw material pails is charging aperture, under shed is discharging opening, which is provided with the magnetic valve of control discharging, this magnetic valve links to each other with discharge nozzle one end, and the port of export of this discharge nozzle is positioned at the filling cylinder above the opening in home position.This filling cylinder is the cylinder of lower end closed, and its bottom is fixed on the flat push-and-pull sliding plate, is provided with the horizontal slideway that is fixed on the support below the sliding plate.Filling cylinder and corresponding slideway bottom are provided with outlet, which is provided with anti-backflow individual event valve, and this check valve links to each other with output sebific duct one end, and this output sebific duct other end can be enclosed within on the injection head.Also be provided with anti-negative one-way valve at sliding plate and filling cylinder bottom portion.Support at above-mentioned slide rail one end is provided with the axis push-and-pull cylinder parallel with slide rail, and the piston rod of this push-and-pull cylinder links to each other with filling cylinder sliding plate.Being provided with an axis near the support corresponding with the shortest position of push-and-pull cylinder piston rod contraction is vertical stirring motor lift cylinder, the piston rod upper end of this cylinder links to each other with coupling bar one end of level, the coupling bar other end of this level links to each other with the stirring motor slide plate, the motor slide plate that motor base should fixedly be arranged, its swallow-tail form slide block is positioned on the vertical dovetail slideway, this slideway is fixed on the support, as shown in Figure 3.Vertical stirring motor rotating shaft lower end is provided with the impeller corresponding with the cylinder of annotating.Be vertical extruding cylinder with being provided with an axis filling cylinder is shifted onto the corresponding support of highest distance position by the push-and-pull cylinder above in addition, this is provided with the gas balance pressure detection switch above extruding cylinder, following piston rod free end is provided with perpendicular continuous disc extruding disk, and its diameter is slightly smaller than the filling cylinder diameter.Above-mentioned push-and-pull cylinder, extruding cylinder and stirring motor lift cylinder, all be equipped with two separately at two ends and be used for the magnetic switch of control automatically, and and the wiring of the magnetic valve wiring of Raw material pail and stirring motor constitute relay logic circuit, in the rack-mount electric cabinet.In circuit diagram of the present invention shown in Figure 4, among the figure, ZJ is relay, and SJ is timer, and SL is magnetic valve, ck1-1, ck1-2 are the magnetic switch at stirring motor lift cylinder two ends, ck2-1, ck2-2 are the magnetic switch at push-and-pull cylinder two ends, and ck3-1, ck3-2 are the magnetic switch at extruding cylinder two ends, and stirring motor lift cylinder, push-and-pull cylinder and extruding cylinder are respectively by HX1, HX2, the commutation of HX3 reversal valve, M is stirring motor, and Q is the equalizing pressure sense switch.As the start button KA that presses branch road 1, after, KA is by the ZJ1 self-locking, simultaneously, power supply indicator, ZJ, ZJ1 gets.The contact ZJ1 closure of branch road 2, timer SJ1, SJ2 SJ3 must establish the beginning timing by cable, normal battle of ZJ closure on the branch road 3, the magnetic valve SL1 SL2 SL3 of Raw material pail outlet gets electric opening, beginning is injected raw material to the filling cylinder, it all is different that each timer arranges the time, after last timer disconnects, article 4,3 SJ contacts of branch road are all closed, ZJ2 gets electric adhesive, the ZJ2 contact adhesive of the 5th branch road, the reversal valve HX1 of No. 1 cylinder gets by normally closed some SJ4, the reversal valve commutation, No. 1 cylinder band stirring motor and is moved downward, enter in the filling cylinder, cylinder runs to the shortest some stop of piston rod, owing to have magnet ring on the piston, during to the shortest, the magnetic induction switch CK1-2(that is placed by the outside at the shortest some place sees branch road 6) sense the CK1-2 closure, timer SJ4, relay ZJ3 gets electric adhesive by normally closed some ZJ6, the ZJ3 closure on the 7th branch road, and stirring motor M must establish the beginning running by cable, stir raw material, after the time that SJ4 sets arrived, the SJ4 contact on the branch road 7 disconnected, the running of stirring motor outage stop, SJ4 contact on the 5th branch road also disconnects, the HX1 dead electricity, commutation again, cylinder 1 is being with stirring motor up, reach highest point, make the stirring motor impeller break away from the filling cylinder, and sense the CK1-1 of cylinder upper end, (branch road 8) makes its closure, because the SJ4 of branch road 8 or closure, (pin CK1-2 the ZJ3 contact on the branch road 6, makes CK1-2 disconnect SJ4 even the lower dead center of cylinder 1 piston breaks away from CK1-2, ZJ3 still electric adhesive) the reversal valve HX2 of No. 2 cylinders gets electric commutation, promoting the filling cylinder and come under the extruding disk, at this moment has been its range, and by the CK2-2 of this cylinder end
(branch road 9) sensed, and closed, makes the reversal valve HX3 of No. 3 cylinders get electric commutation by normally closed some ZJ4, and extruding disk is pushed downwards.The pressure of this cylinder is configured in advance by pressure-reducing valve.When extruding disk is expressed to the bottom of filling cylinder, be the range of No. 3 cylinders, finish the work, plunger magnetic ring is sensed by CK3-2, CK3-2 closure, ZJ4, ZJ7 gets electric adhesive, and another kind of situation is that the filling cylinder has not been annotated, at this moment, equalizing pressure sense switch Q has detected the pressure of sample filling and the pressure of air inlet has reached balance, the Q adhesive, ZJ4, ZJ7 get electric adhesive, and Q is by the ZJ4 self-locking, ZJ4 contact on the branch road 9 disconnects, the HX3 commutation, extruding disk rises, when, when extruding disk rises to the end, the closed CK3-1 of No. 3 cylinder ends makes the ZJ5 adhesive, and the contact ZJ5 on the branch road 8 disconnects, the HX2 commutation of cutting off the power supply, No. 2 cylinders are retracted initial point, and touch the CK2-1 closure, make the ZJ6 conducting, make branch road 1 outage, entire circuit resets.

Claims (2)

1. intelligent sample developer perfusion equipment, it is characterized in that: support is provided with Raw material pail, the upper shed of these Raw material pails is charging aperture, under shed is discharging opening, which is provided with magnetic valve, this magnetic valve links to each other with discharge nozzle one end, the port of export of this discharge nozzle is positioned at the filling cylinder above the opening in home position, this filling cylinder bottom portion is fixed on the push-and-pull sliding plate, be provided with the horizontal slideway that is fixed on the support below this sliding plate, filling cylinder and corresponding slideway bottom are provided with outlet, which is provided with anti-backflow check valve, this check valve links to each other with output sebific duct one end, this output sebific duct other end can be enclosed within on the syringe nozzle, support at horizontal slideway one end is provided with the axis push-and-pull cylinder parallel with slideway, the piston rod of this push-and-pull cylinder links to each other with filling cylinder sliding plate, being provided with an axis near the support corresponding with the shortest position of push-and-pull cylinder piston rod contraction is vertical stirring motor lift cylinder, the piston rod upper end of this stirring motor lift cylinder links to each other with coupling bar one end of level, the coupling bar other end of this level links to each other with the stirring motor slide plate, the motor slide plate that motor base should fixedly be arranged, its swallow-tail form slide block is positioned on the vertical dovetail slideway, this slideway is fixed on the support, vertical stirring motor rotating shaft lower end is provided with the impeller corresponding with the cylinder of annotating, this impeller can stretch in the filling cylinder, be vertical extruding cylinder with being provided with an axis filling cylinder is shifted onto the corresponding support of highest distance position by the push-and-pull cylinder above in addition, this is provided with the gas balance pressure detection switch above extruding cylinder, following piston rod free end is provided with perpendicular continuous disc extruding disk, its diameter is slightly smaller than the filling cylinder diameter, above-mentioned push-and-pull cylinder, extruding cylinder and stirring motor lift cylinder, two magnetic switch all are housed at two ends separately, and and the magnetic valve wiring of Raw material pail and stirring motor wiring constitute relay logic circuit, in the rack-mount electric cabinet.
2. intelligent shape sample developer perfusion equipment according to claim 1 is characterized in that: be provided with anti-negative one-way valve at above-mentioned sliding plate and filling cylinder bottom portion.
CN 201110315545 2011-10-18 2011-10-18 Intelligent specimen developer filling device Expired - Fee Related CN102500508B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 201110315545 CN102500508B (en) 2011-10-18 2011-10-18 Intelligent specimen developer filling device

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Application Number Priority Date Filing Date Title
CN 201110315545 CN102500508B (en) 2011-10-18 2011-10-18 Intelligent specimen developer filling device

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CN102500508A CN102500508A (en) 2012-06-20
CN102500508B true CN102500508B (en) 2013-08-21

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CN105476609B (en) * 2016-01-24 2018-06-08 福建省裕景建筑工程有限公司 A kind of pinpoint accuracy Olfactometry device
CN109395915B (en) * 2018-10-11 2022-05-13 上海船舶工艺研究所(中国船舶工业集团公司第十一研究所) Conveying device for high-viscosity materials with low flowing property and using method

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US9144583B2 (en) * 2002-03-29 2015-09-29 Tissue Genesis, Inc. Cell separation apparatus and methods of use
CN100522388C (en) * 2007-01-24 2009-08-05 大连鸿峰生物科技有限公司 Glue injection machine dedicated for biological plasticized silicone rubber
CN201097580Y (en) * 2008-01-18 2008-08-13 韩淑云 Electric automatic control constant pressure bulking agent bottler
WO2010036726A1 (en) * 2008-09-23 2010-04-01 Cedars-Sinai Medical Center Methods and apparatus for perfusion of an explanted donor heart
CN202343396U (en) * 2011-10-18 2012-07-25 大连鸿峰生物科技有限公司 Intelligent filling equipment for specimen developer

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Granted publication date: 20130821

Termination date: 20161018