CN102451287B - External traditional Chinese medicine foot bath medicament for treating gout and preparation method thereof - Google Patents
External traditional Chinese medicine foot bath medicament for treating gout and preparation method thereof Download PDFInfo
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- CN102451287B CN102451287B CN 201110457126 CN201110457126A CN102451287B CN 102451287 B CN102451287 B CN 102451287B CN 201110457126 CN201110457126 CN 201110457126 CN 201110457126 A CN201110457126 A CN 201110457126A CN 102451287 B CN102451287 B CN 102451287B
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Abstract
The invention relates to the technical fields of an external traditional Chinese medicine foot bath liquid for treating gout and a preparation method thereof, and provides the external traditional Chinese medicine foot bath liquid for treating gout and the preparation method thereof. The external traditional Chinese medicine foot bath medicament for treating gout is prepared from the following traditional Chinese medicine raw materials: dogbane leaf, peganum harmala seed, vernonia anthelmintica, mint leaf, licorice, saussurea involucrata and prepared rehmannia. The external traditional Chinese medicine foot bath medicament for treating gout provided by the invention is clinically verified to have the advantages of effectively lowering uric acid level in blood and reducing patient pain, being practical, convenient and rapid in curative effect, having the efficacies of resolving heat and promoting blood circulation, reducing stagnation and detoxifying, expelling pathogenic wind and dampness as well as dredging collaterals and relieving pain, and realizing the treatment on gout disease.
Description
Technical field
The present invention relates to treat Chinese medicine external foot bath liquid and preparation method thereof the technical field of gout, is a kind of gout Chinese medicine external Pediluvium medicament and preparation method thereof for the treatment of.
Background technology
Gout claims " hyperuricemia " again, the purine metabolism obstacle, and it is a kind of to belong to arthritis.Gout is that the metabolism of the material of purine in the human body gets muddled, and the synthetic increase of uric acid or discharge reduce, and cause hyperuricemia, during the blood uric acid excessive concentration, uric acid is deposited in joint, cartilage and the kidney with the form of sodium salt, causes to organize foreign body inflammatory reaction, i.e. gout.
Long-term patient with gout has and shows effect in finger-joint, even auricle contains the case of soft tissue portion.That the gouty attack,acute position occurs is red, swollen, hot, have an intense pain, and general manyly show effect the midnight can make the people wake up with a start from sleep.At the gout initial stage, lower limb are more common in outbreak.
When blood uric acid just is saturation (at pH7.4 above 7mg/dl or 400umol/L blood plasma, under 37 ℃ of temperature and the serum sodium normal condition). in the time of 30 ℃, uratic dissolubility is 4mg/dl, therefore aciculiform monosodium urate salt (MSU) will supply few relatively tissue (as tendon for (as cartilage) or blood at depletion of blood, ligament) deposition, these positions comprise joint on every side and the lower tissue of picture ear equitemperature of far-end.The patient serious and sick time is long, the crystallization of monosodium urate salt can deposit in the big joint of central authorities and organa parenchymatosum such as kidney, and forms tophus.
Modern Western medicine is drained uric acid medicine such as medicines such as probenecid, benzbromarone because toxic and side effects is bigger, and the patient often can not adhere to taking for a long time at medicine such as the anti-inflammation analgesia medicine colchicine of gout, so that the wayward state of an illness.
Summary of the invention
The invention provides a kind of gout Chinese medicine external Pediluvium medicament and preparation method thereof for the treatment of, overcome the deficiency of prior art, its practicality, convenience, curative effect are fast, have the effect of heat clearing and blood circulation promoting, powder detoxifcation, evil-wind expelling and dampness removing removing obstruction in the collateral to relieve pain, have realized the treatment to gout.
One of technical scheme of the present invention realizes by following measure: a kind of gout Chinese medicine external Pediluvium medicament for the treatment of, it is made by following raw material of Chinese medicine weight portion: 0.5 part of 6 parts to 9 parts of Folium Apocyni Veneti, Peganum harmala L to 2,1 part to 2 parts of Caulis Vernoniae andersonii, 4 parts to 7 parts of mentha leavves, 1 part to 2 parts in Radix Glycyrrhizae, 0.5 part to 2 parts of Herba Saussureae Involueratae, 1 part to 3 parts in Radix Rehmanniae Preparata.
Below one of technique scheme is done further to optimize or/and select:
Above-mentioned treatment gout Chinese medicine external Pediluvium medicament also can be made by following raw material of Chinese medicine weight portion: 8 parts of Folium Apocyni Venetves, 1 part of Peganum harmala L, 1 part of Caulis Vernoniae andersonii, 6 parts of mentha leavves, 1 part in Radix Glycyrrhizae, 1 part of Herba Saussureae Involueratae, 2 parts in Radix Rehmanniae Preparata.
Above-mentioned treatment gout Chinese medicine external Pediluvium medicament can be lavipeditum powder.
Above-mentioned treatment gout Chinese medicine external Pediluvium medicament can be footbath with traditional Chinese medicines liquid, and this footbath with traditional Chinese medicines liquid is the former material of the Chinese medicine of requirement to be pulverized add the heating of 1000 weight portion purified water and be concentrated into 500 weight portions and namely get the Chinese medicine concentrated solution; Namely obtain footbath with traditional Chinese medicines liquid after in above-mentioned Chinese medicine concentrated solution, adding sodium bicarbonate 5 weight portion to 15 weight portions, magnesium chloride 1 weight portion to 3 weight portion, potassium chloride 1 weight portion to 3 weight portion again and adding the nipagin ester that meets the pharmacopeia ormal weight.
Two of technical scheme of the present invention realizes by following measure: a kind of preparation method of above-mentioned treatment gout Chinese medicine external Pediluvium medicament, its described medicine is footbath with traditional Chinese medicines liquid, and this footbath with traditional Chinese medicines liquid is undertaken by following step: the former material of the Chinese medicine of requirement is pulverized added the heating of 1000 weight portion purified water and be concentrated into 500 weight portions and namely get the Chinese medicine concentrated solution; Namely obtain footbath with traditional Chinese medicines liquid after in above-mentioned Chinese medicine concentrated solution, adding sodium bicarbonate 5 weight portion to 15 weight portions, magnesium chloride 1 weight portion to 3 weight portion, potassium chloride 1 weight portion to 3 weight portion again and adding the nipagin ester that meets the pharmacopeia ormal weight.
The present invention treats gout Chinese medicine external Pediluvium medicament can effectively reduce uric acid level in the blood through clinical verification, reduce the patient suffering, and practical, convenient, curative effect is fast, has the effect of heat clearing and blood circulation promoting, powder detoxifcation, evil-wind expelling and dampness removing removing obstruction in the collateral to relieve pain, has realized the treatment to gout.
The specific embodiment
The present invention is not subjected to the restriction of following embodiment, can determine concrete embodiment according to technical scheme and the practical situation of the invention described above.
Do further argumentation below in conjunction with the present invention of embodiment:
Embodiment 1, and this treatment gout Chinese medicine external Pediluvium medicament is made by following raw material of Chinese medicine weight portion: 0.5 part of 6 parts to 9 parts of Folium Apocyni Veneti, Peganum harmala L to 2,1 part to 2 parts of Caulis Vernoniae andersonii, 4 parts to 7 parts of mentha leavves, 1 part to 2 parts in Radix Glycyrrhizae, 0.5 part to 2 parts of Herba Saussureae Involueratae, 1 part to 3 parts in Radix Rehmanniae Preparata.
Embodiment 2, and this treatment gout Chinese medicine external Pediluvium medicament is made by following raw material of Chinese medicine weight portion: 6 parts of Folium Apocyni Venetves, 0.5 part of Peganum harmala L, 1 part of Caulis Vernoniae andersonii, 4 parts of mentha leavves, 1 part in Radix Glycyrrhizae, 0.5 part of Herba Saussureae Involueratae, 1 part in Radix Rehmanniae Preparata.
Embodiment 3, and this treatment gout Chinese medicine external Pediluvium medicament is made by following raw material of Chinese medicine weight portion: 9 parts of Folium Apocyni Venetves, Peganum harmala L 2,2 parts of Caulis Vernoniae andersoniis, 7 parts of mentha leavves, 2 parts in Radix Glycyrrhizae, 2 parts of Herba Saussureae Involueratae, 3 parts in Radix Rehmanniae Preparata.
Embodiment 4, and this treatment gout Chinese medicine external Pediluvium medicament is made by following raw material of Chinese medicine weight portion: 8 parts of Folium Apocyni Venetves, 1 part of Peganum harmala L, 1 part of Caulis Vernoniae andersonii, 6 parts of mentha leavves, 1 part in Radix Glycyrrhizae, 1 part of Herba Saussureae Involueratae, 2 parts in Radix Rehmanniae Preparata.
Embodiment 5, and be with the difference of embodiment 1 to embodiment 4: the treatment gout Chinese medicine external Pediluvium medicament of embodiment 5 is lavipeditum powder.
Embodiment 6, be with the difference of embodiment 1 to embodiment 5: the treatment gout Chinese medicine external Pediluvium medicament of embodiment 6 is footbath with traditional Chinese medicines liquid, and this footbath with traditional Chinese medicines liquid is the former material of the Chinese medicine of requirement to be pulverized add the heating of 1000 weight portion purified water and be concentrated into 500 weight portions and namely get the Chinese medicine concentrated solution; Namely obtain footbath with traditional Chinese medicines liquid after in above-mentioned Chinese medicine concentrated solution, adding sodium bicarbonate 5 weight portion to 15 weight portions, magnesium chloride 1 weight portion to 3 weight portion, potassium chloride 1 weight portion to 3 weight portion again and adding the nipagin ester that meets the pharmacopeia ormal weight.
The footbath with traditional Chinese medicines liquid of above-described embodiment gained is carried out following clinical trial:
1, case is selected:
Select gout case 60 examples, male 40 examples, women 20 examples, the age is between 35-65 year, wherein gout position toe joint redness or pain 12 examples, naked redness and swelling of joints or pain 18 examples, knee joint redness or pain 21 examples, articulations digitorum manus, carpal joint redness or pain 9 examples.
2, Therapeutic Method:
250 milliliters of footbath with traditional Chinese medicines liquid (if any precipitation, please shake up during use) are added in the hot water of 5000 milliliters of 40-55 degree, stir evenly, biped soaked 40-60 minute, and be a course for the treatment of at twice, 7 day sooner or later every day.
3, therapeutic effect criterion:
Produce effects: the serum uric acid value reaches normal level (200-420umol/L), transference cure or obviously alleviate.
Effectively: the serum uric acid value obviously descends, but does not also reach normal level, sx or alleviation.
Invalid: as to improve with nothing before the treatment.
4, model case:
| Name | Sex | Age | Serum uric acid value (umol/L) before the treatment | Treatment back serum uric acid level (umol/L) | Serum uric acid reference value (umol/L) |
| Mr. Li | The man | 48 | 673 | 380 | 200-420 |
| Mr. Ji | The man | 56 | 586 | 377 | 200-420 |
| Mr. Wang | The man | 48 | 525 | 353 | 200-420 |
| Mr. Liu | The man | 36 | 637 | 398 | 200-420 |
| Mr. Zhao | The man | 57 | 658 | 410 | 200-420 |
| Hot Ms | The woman | 50 | 702 | 361 | 200-420 |
| The Ms Zhang | The woman | 54 | 498 | 325 | 200-420 |
| Mr. Wang | The man | 36 | 686 | 411 | 200-420 |
| Buy the Ms | The woman | 46 | 753 | 401 | 200-420 |
| Mr. Ma | The man | 59 | 727 | 387 | 200-420 |
| Mr. Li | The man | 62 | 696 | 346 | 200-420 |
| Mr. Shao | The man | 47 | 648 | 407 | 200-420 |
| Mr. Xue | The man | 48 | 594 | 379 | 200-420 |
| Tell Mr. | The man | 41 | 715 | 364 | 200-420 |
| Mrs Cheng | The woman | 53 | 690 | 382 | 200-420 |
| Mr. Wang | The man | 49 | 575 | 390 | 200-420 |
| Breathe out Mr. | The man | 45 | 685 | 415 | 200-420 |
5, clinical therapeutic efficacy statistics:
60 routine gout cases are chosen in this test, and the result was as follows after wherein process above-described embodiment gained footbath with traditional Chinese medicines liquid product was treated 1 to 2 course for the treatment of: produce effects 41 examples, effective 18 examples, invalid 1 example, total effective rate 99%.
In sum, the position of gout is in the little joints of far-end such as lower limb and the sole of the foot, toe, ankle and fingers, according to theory of Chinese medical science, skin and extremity belong to table, according to the principle of outer sick external treatment, with gained footbath with traditional Chinese medicines vacuole foot of the present invention the affected part is treated, by the Transdermal absorption effect to medicinal liquid, symptoms such as rapid alleviation outbreak position appearance is red, swollen, hot, have an intense pain, thus realization is to the treatment of gout.
Claims (5)
1. external Pediluvium medicament for the treatment of gout is characterized in that making by following raw material of Chinese medicine weight portion: 0.5 part of 6 parts to 9 parts of Folium Apocyni Veneti, Peganum harmala L to 2,1 part to 2 parts of Caulis Vernoniae andersonii, 4 parts to 7 parts of mentha leavves, 1 part to 2 parts in Radix Glycyrrhizae, 0.5 part to 2 parts of Herba Saussureae Involueratae, 1 part to 3 parts in Radix Rehmanniae Preparata.
2. the external Pediluvium medicament for the treatment of gout according to claim 1 is characterized in that making by following raw material of Chinese medicine weight portion: 8 parts of Folium Apocyni Venetves, 1 part of Peganum harmala L, 1 part of Caulis Vernoniae andersonii, 6 parts of mentha leavves, 1 part in Radix Glycyrrhizae, 1 part of Herba Saussureae Involueratae, 2 parts in Radix Rehmanniae Preparata.
3. the external Pediluvium medicament for the treatment of gout according to claim 1 and 2 is characterized in that described medicine is lavipeditum powder.
4. the external Pediluvium medicament for the treatment of gout according to claim 1 and 2, it is characterized in that described medicine is footbath with traditional Chinese medicines liquid, this footbath with traditional Chinese medicines liquid is the former material of the Chinese medicine of requirement to be pulverized add the heating of 1000 weight portion purified water and be concentrated into 500 weight portions and namely get the Chinese medicine concentrated solution; Namely obtain footbath with traditional Chinese medicines liquid after in above-mentioned Chinese medicine concentrated solution, adding sodium bicarbonate 5 weight portion to 15 weight portions, magnesium chloride 1 weight portion to 3 weight portion, potassium chloride 1 weight portion to 3 weight portion again and adding the nipagin ester that meets the pharmacopeia ormal weight.
5. the preparation method of the external Pediluvium medicament of a treatment gout according to claim 1 and 2, it is characterized in that described medicine is footbath with traditional Chinese medicines liquid, this footbath with traditional Chinese medicines liquid is undertaken by following step: the former material of the Chinese medicine of requirement is pulverized added the heating of 1000 weight portion purified water and be concentrated into 500 weight portions and namely get the Chinese medicine concentrated solution; Namely obtain footbath with traditional Chinese medicines liquid after in above-mentioned Chinese medicine concentrated solution, adding sodium bicarbonate 5 weight portion to 15 weight portions, magnesium chloride 1 weight portion to 3 weight portion, potassium chloride 1 weight portion to 3 weight portion again and adding the nipagin ester that meets the pharmacopeia ormal weight.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110457126 CN102451287B (en) | 2011-12-31 | 2011-12-31 | External traditional Chinese medicine foot bath medicament for treating gout and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110457126 CN102451287B (en) | 2011-12-31 | 2011-12-31 | External traditional Chinese medicine foot bath medicament for treating gout and preparation method thereof |
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| CN102451287A CN102451287A (en) | 2012-05-16 |
| CN102451287B true CN102451287B (en) | 2013-08-28 |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104383330A (en) * | 2013-07-23 | 2015-03-04 | 佛山市顺德区宝铜金属科技有限公司 | Foot-massage product for clearing heat and removing dampness, and drawing out poison and relieving itching |
| CN106310143A (en) * | 2016-11-14 | 2017-01-11 | 河南中医药大学 | Foot bath drug for treating diabetic foot |
| GB201720992D0 (en) * | 2017-12-15 | 2018-01-31 | Hooper Mark | A medical use |
| CN115040581A (en) * | 2022-07-27 | 2022-09-13 | 山东创新腐植酸科技股份有限公司 | Gout bath lotion and preparation method thereof |
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| CN101897767B (en) * | 2010-07-26 | 2011-11-30 | 浙江中医药大学 | Urarthritis lavipeditum powder |
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Owner name: URUMCHI ROB SHITAN BIOTECHNOLOGY CO., LTD. Free format text: FORMER OWNER: URUMQI HUAJIACHENG PHARMACEUTICAL PACKING CO., LTD. Effective date: 20130726 |
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Effective date of registration: 20130726 Address after: 830011 169 Henan East Road, Urumqi, 7, building 3, the Xinjiang Uygur Autonomous Region Applicant after: Urumqi Huajiacheng Pharmaceutical Packaging Co.,Ltd. Address before: 830011 No. 169 East Henan Road, the Xinjiang Uygur Autonomous Region, Urumqi Applicant before: Urumqi Huajiacheng Pharmaceutical Packing Co., Ltd. |
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