CN102451257B - Traditional Chinese medicinal composition for treating burns and scalds and preparation method thereof - Google Patents

Traditional Chinese medicinal composition for treating burns and scalds and preparation method thereof Download PDF

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CN102451257B
CN102451257B CN 201010512646 CN201010512646A CN102451257B CN 102451257 B CN102451257 B CN 102451257B CN 201010512646 CN201010512646 CN 201010512646 CN 201010512646 A CN201010512646 A CN 201010512646A CN 102451257 B CN102451257 B CN 102451257B
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empyrosis
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李爱娣
王其
李新
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李爱娣
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Abstract

The invention relates to a traditional Chinese medicinal composition for treating burns and scalds and a preparation method thereof. The composition is characterized in that the composition is prepared from the following raw material components, by weight, 1-90 parts of gypsum, 26-100 parts of stalactite, 1-100 parts of Boswellia carteri, 31-70 parts of myrrh, 27-90 parts of Rheum officinale and 30-100 parts of catechu or Radix Sanguisorbae. The preparation method comprises the following steps: 1, cleaning the raw material components according to above weight parts; 2, respectively grinding them into powders after air drying; 3, mixing the powders; 4, adding sesame oil having a weight 1-100 times of raw material components to the obtained powdery product; and 5, stirring to obtain a pastyproduct. According to the traditional Chinese medicinal composition, the cure period to the burns and the scalds is short, first degree burns or scalds can be healed after 3-5 days, second degree burns or scalds can be healed after 6-7 days, and third degree burns or scalds can be healed after about half a month. The composition is replaced by a patient 1-2 times each day, so convenience is provided for the patient. In addition, the cure rate of the composition reaches 100%.

Description

A kind of Chinese medicine composition for the treatment of empyrosis and preparation method thereof
Technical field
The present invention relates to compositions, specifically, relate to Chinese medicine composition.
Background technology
Burn, scald are the situation that often runs in life.Will be according to the size of burn after the burn, the order of severity is taken measures targetedly.The first aid of burn mainly comprises cooling and protection affected part.If skin is still complete behind the burn, should make as early as possible local cooling.As be placed under the faucet and wash, can take away like this local organization heat and reduce further infringement.Subsequently, with the mat wrapping injury of a soft humidity, preferably sterilization, note too not tight.If patient's burn site has played vesicle, should protect part or cooling.During with clean water flushing affected part, note not puncturing or fray vesicle to protect from infection.If injury swelling should be removed jewelry, use continuously the cold water flush injury.Then with not with the dressing of stickiness or moist, preferably the mat of sterilizing gently covers on the vesicle, unless vesicle is very little, otherwise the patient must be sent to hospital.
When if there is glutinous the company in patient's clothes and affected part, should the clothes around the affected part be cut off with shears, allow as far as possible the affected part come out, cover gently with the gauze that cleans.If clothes catches fire, note not allowing the wounded run, can agitate flame because do like this.Cover big fire with a large blanket, clothes, rag or analog.Pledge clothes when burning, clothes should be sloughed, but will stay the part of sticking together with health.With moist coverlet or analog the wounded is wrapped up, send inspection to hospital.
If skin burns out, cover on it to protect the injury, the minimizing risk of infection with a clean mat.If the degree of patient's burn is very serious, the sign of carbonization has appearred in some skin, at this moment must not touch the affected part, avoids causing the secondary damage in affected part because processing too much.Scald is the burn that is caused by the liquid that scalds, and at first will wash away with cold water the liquid of heat, and local cooling 10 minutes, and with clean, a moist dressing covering.If scald in the oral cavity, because swelling may affect respiratory tract, so first aid must be fast, makes the patient break away from thermal source, places cool place, and keep stable lateral position, waits for rescue.If during chemicals (sulphuric acid, Caustic soda etc.) burned skin, should will remain in chemicals with dry towel and remove gently at once, then use a large amount of cold water flush.But some chemicals can play violent chemical reaction with water such as sulphuric acid etc., necessarily not directly water flushing.
Above-mentioned all is common emergency treatments of taking for the empyrosis in the daily life, even but the patient processes wound in the very first time, but still can there be a lot of problems in the skin of most of patients, stay scar very serious such as wound, even the serious consequence of amputation is arranged, because burn, scald except once: only injure epidermis, the traumatic part skin rubefaction, swelling, burning pain; Two degree, traumatic part skin is got blister, heating, the outer third degree burn that occurs of hurt like hell is scalded, and skin burnt meat in traumatic part is mashed, and serious hinders to muscles and bones.
Application number: 200510019306.2 patent application patent disclose " a kind of medicine for the treatment of empyrosis ... made by Radix Sanguisorbae, Radix Et Rhizoma Rhei, Mirabilitum crystallina, Oleum Camelliae."; This patent application patent " have anti-inflammatory analgetic, heat clearing away annealing, infection, granulation promoting, do not stay or stay less cicatrix after more ... " the disclosed medicine of this patent application patent still has the possibility of cicatrix, and whether all effectively to all empyrosis do not specify, and for the traumatic condition that blister is arranged, needed for two weeks could cure, the cycle is still comparatively very long.
At present, the medication effect of most treatment empyrosis is not very good, the cycle that some drugs needs when the treatment empyrosis is longer, or still has the phenomenon of cicatrix after the treatment, or the dosage that need every day often, bring inconvenience to the patient, the medicine that is exactly in addition is when the treatment empyrosis, and the patient can not walk about outdoor, has limited patient's activity, or in medicine, add too much chemical composition, patient's health is caused potential harm.
Summary of the invention
The object of the invention is in view of the foregoing defects the prior art has, a kind of Chinese medicine composition for the treatment of empyrosis is provided, this Chinese medicine composition is not only short to empyrosis punishment more cycle, 1 degree is burnt or is scalded and can fully recover in 3 to 5 days, and 2 degree burns or scald can be fully recovered in 6-7 days, and 3 degree are burnt or scalded two weeks and get final product, the patient only needs to change a 1-2 medicine in and gets final product, for the patient brings convenience, in addition, the said composition cure rate reaches 100%.
Second purpose of the present invention is, a kind of preparation method for the treatment of the Chinese medicine composition of empyrosis is provided.
A kind of Chinese medicine composition for the treatment of empyrosis provided by the invention, its improvements are that described compositions comprises that the following raw materials according component is prepared from: Gypsum Fibrosum, Mirabilitum crystallina, Olibanum, Myrrha, Radix Et Rhizoma Rhei and catechu or Radix Sanguisorbae.
The Chinese medicine composition of the provided by the invention first preferred treatment empyrosis, described compositions comprises that following raw materials according component by weight is prepared from:
Gypsum Fibrosum 1-90, Mirabilitum crystallina 26-100, Olibanum 1-100, Myrrha 31-70, Radix Et Rhizoma Rhei 27-90 and catechu or Radix Sanguisorbae 30-100.
The Chinese medicine composition of the provided by the invention second preferred treatment empyrosis, described compositions comprises that following raw materials according component by weight is prepared from:
Gypsum Fibrosum 10-75, Mirabilitum crystallina 40-85, Olibanum 10-90, Myrrha 40-65, Radix Et Rhizoma Rhei 30-80 and catechu or Radix Sanguisorbae 30-100.
The Chinese medicine composition of the provided by the invention the 3rd preferred treatment empyrosis, described compositions comprises that following raw materials according component by weight is prepared from:
Gypsum Fibrosum 25-50, Mirabilitum crystallina 50-70, Olibanum 30-70, Myrrha 45-60, Radix Et Rhizoma Rhei 40-60 and catechu or Radix Sanguisorbae 50-80.
The Chinese medicine composition of the provided by the invention the 4th preferred treatment empyrosis, the product forms that described compositions is prepared is paste, Powdered and liquid preparation.
The Chinese medicine composition of the provided by the invention the 5th preferred treatment empyrosis, described compositions comprise that weight is the 1-100 Oleum sesami doubly of raw material components weight.
A kind of method for preparing the Chinese medicine composition of empyrosis provided by the invention may further comprise the steps:
With above-mentioned raw material components by weight, to clean, the rear mixing that is ground into powder after drying can obtain powdery product;
A kind of method for preparing the Chinese medicine composition of empyrosis provided by the invention may further comprise the steps:
With above-mentioned raw material components by weight, to clean, the rear mixing that is ground into powder after drying adds the 1-100 Oleum sesami doubly that weight is raw material components weight in step in the powdery product that obtains, namely get the paste product after the stirring.
A kind of method for preparing the Chinese medicine composition of empyrosis provided by the invention may further comprise the steps:
With above-mentioned raw material components by weight, clean, rear mixing is ground into powder after drying, adding 1-10 water doubly in the powdery product that obtains makes the water that adds can cover raw material components, then under 50-100 ℃ of temperature, boil 10-120 minute after, cold filtration namely gets liquid preparation.
The preparation method of the Chinese medicine composition of the provided by the invention first preferred empyrosis, the granularity after described powder grinds is the 10-150 order.
The patient when using medicine of the present invention, burn or scald broken skin no matter whether occurs, all without the gauze parcel, with wound with the disinfectant cleaning after, smear compositions of the present invention, changing dressings in one day gets final product for 1 time; The employing of broken skin ointment of the present invention or medicated powder do not spread upon the affected part, and scald or burn a few days ago also can be changed dressings 1-3 time in one day; The liquid preparation of pharmaceutical composition of the present invention namely can be used for the broken skin affected part, also can be used for the not affected part of broken skin.
Weight portion of the present invention can be gram, kilogram or kilogram, liang, jin, ton etc.
Compared with prior art, a kind of Chinese medicine composition for the treatment of empyrosis provided by the invention and preparation method thereof has the following advantages:
1, the healing cycle short, instant effect, and preventing from scar;
The number of times of 2, changing dressings every day is few, brings a lot of convenience to the patient, and has reduced patient's economic investment;
3, using method is simple, does not need to be combined with other antibiotics;
Even 4 third degree burns, two weeks can be cured fully;
5, the patient can be freely movable at indoor or outdoors in therapeutic process;
6, preparation method is simple, and cost is low, can carry out Produce on a large scale;
7, pharmaceutical composition is long placed in and undergoes no deterioration;
8, can make ointment, liquid preparation or Powdered, the affected part that is coated in the patient does not have pain;
9, burn surface area is treated and can be fully recovered in 5-14 days when 30%-50%;
10, the cure rate of 1 degree, 2 degree or 3 degree burns or scald all can reach 100%;
11, all effective to the empyrosis patient of all ages and classes section;
12, easy infection not can be treated at common environment, does not have the requirement of gnotobasis;
13, after serious burn or the scald, do not need to arrange sterilizing room, do not need infrared ray radiation or skin-grafting;
14, be applicable to all kinds of burns or scald.
The specific embodiment
Below by specific embodiment a kind of Chinese medicine composition for the treatment of empyrosis provided by the invention and preparation method thereof is done further more detailed description;
Correlation test
Clinical trial
A, extract 3000 example burns or scald the case patient immediately, unguentum or powder or the liquid preparation of the Chinese medicine composition that these patients' burn or scald place applied treatment empyrosis of the present invention are observed after the treatment and statistical result sees Table 1;
Table 1 adopts the Chinese medicine composition for the treatment of empyrosis of the present invention to burn or scald patient treatment situation
Figure BSA00000310185600041
B, following for adopting the some patients were treatment situation after the compositions of the present invention
Wu's woman's 3 months ages shank and thigh place are scalded by boiled water, and the scald place is red and swollen, bubble, burn surface area reach 10% smear medicine unguentum of the present invention after, afterwards recovery from illness in 3 days, and scald place preventing from scar, the patient does not have pain in the process of the drug of topical application, cure rate reaches 100%;
Grandson woman is burnt at 60 years old age arm place, and burn surface area reaches 28%, the broken skin phenomenon occurs, apply compositions medicated powder of the present invention after, recovery from illness in 5 days, affected part preventing from scar after curing, cure rate reaches 100%;
At Liu's 47 years old age of man, step is burnt, and belongs to serious burn, and burn surface area reaches 35%, the drug of topical application afterwards recovery from illness in 12 days, preventing from scar after curing;
Lee's 12 years old age of man, the shank burn is serious, being in a bad way after hospitalize a period of time, rots in the affected part, takes at last to treat after the amputation again, the state of an illness is still seriously uncontrollable, patient's pain can't bear, and wound deterioration infects, rear employing combination treatment of the present invention after 7 days the state of an illness greatly take a turn for the better, afterwards recovery from illness in 14 days is not stayed scar after healing.
C, adopt respectively pharmaceutical composition of the present invention and application number to be respectively 02145522.8,200510019306.2,03111720.1,200810010712.6,200910074570.4 Drug therapy to the patient of third degree burn or scald, relatively their drug effect situation sees Table 2;
The drug effect situation relatively after table 2 adopted medicine of the present invention and application number to be respectively 02145522.8,200510019306.2,03111720.1,200810010712.6,200910074570.4 medicine
Figure BSA00000310185600052
Embodiment 1
The Chinese medicine composition of the treatment empyrosis of the present embodiment is prepared from by by weight following raw materials according component:
Gypsum Fibrosum 1 gram, Mirabilitum crystallina 26 grams, Olibanum 1 gram, Myrrha 31 grams, Radix Et Rhizoma Rhei 27 grams and catechu 30 grams.
The preparation method of the Chinese medicine composition of the treatment empyrosis of the present embodiment may further comprise the steps:
1), with the raw material components of above-mentioned weight portion meter, clean, the rear mixing that is ground into powder after drying can obtain powdery product;
Wherein, the granularity after powder grinds is 20 orders.
Embodiment 2
The Chinese medicine composition of the treatment empyrosis of the present embodiment is prepared from by by weight following raw materials according component:
Gypsum Fibrosum 10 grams, Mirabilitum crystallina 40 grams, Olibanum 10 grams, Myrrha 40 grams, Radix Et Rhizoma Rhei 30 grams and Radix Sanguisorbae 30 grams.
The preparation method of the Chinese medicine composition of the treatment empyrosis of the present embodiment may further comprise the steps:
1), with the raw material components of above-mentioned weight portion meter, clean, the rear mixing that is ground into powder after drying can obtain powdery product;
2), in step 1) to add weight in the powdery product that obtains be 1 times Oleum sesami of raw material components weight, namely gets the paste product after the stirring;
Wherein, the granularity after powder grinds is 80 orders.
Embodiment 3
The Chinese medicine composition of the treatment empyrosis of the present embodiment is prepared from by by weight following raw materials according component:
Gypsum Fibrosum 25 grams, Mirabilitum crystallina 50 grams, Olibanum 30 grams, Myrrha 45 grams, Radix Et Rhizoma Rhei 40 grams and Radix Sanguisorbae 50 grams.
The preparation method of the Chinese medicine composition of the treatment empyrosis of the present embodiment may further comprise the steps:
1), with the raw material components of above-mentioned weight portion meter, clean, the rear mixing that is ground into powder after drying can obtain powdery product;
2), in step 1) water that adds 1 times in the powdery product that obtains makes the water that adds can cover raw material components, then under 50 ℃ of temperature, boil 10 minutes after, cold filtration namely gets liquid preparation.
Wherein, the granularity after powder grinds is 120 orders.
Embodiment 4
The Chinese medicine composition of the treatment empyrosis of the present embodiment is prepared from by by weight following raw materials according component:
Gypsum Fibrosum 90 grams, Mirabilitum crystallina 100 grams, Olibanum 100 grams, Myrrha 70 grams, Radix Et Rhizoma Rhei 90 grams and catechu 100 grams.
The preparation method of the Chinese medicine composition of the treatment empyrosis of the present embodiment may further comprise the steps:
1), with the raw material components of above-mentioned weight portion meter, clean, the rear mixing that is ground into powder after drying can obtain the powdery product;
Wherein, the granularity after powder grinds is 10 orders.
Embodiment 5
The Chinese medicine composition of the treatment empyrosis of the present embodiment is prepared from by by weight following raw materials according component:
Gypsum Fibrosum 75 grams, Mirabilitum crystallina 85 grams, Olibanum 90 grams, Myrrha 65 grams, Radix Et Rhizoma Rhei 80 grams and Radix Sanguisorbae 100 grams.
The preparation method of the Chinese medicine composition of the treatment empyrosis of the present embodiment may further comprise the steps:
1), with the raw material components of above-mentioned weight portion meter, clean, the rear mixing that is ground into powder after drying can obtain powdery product;
2), in step 1) water that adds 10 times in the powdery product that obtains makes the water that adds can cover raw material components, then under 100 ℃ of temperature, boil 120 minutes after, cold filtration namely gets liquid preparation;
Wherein, the granularity after powder grinds is 150 orders.
Embodiment 6
The Chinese medicine composition of the treatment empyrosis of the present embodiment is prepared from by by weight following raw materials according component:
Gypsum Fibrosum 50 grams, Mirabilitum crystallina 70 grams, Olibanum 70 grams, Myrrha 60 grams, Radix Et Rhizoma Rhei 60 grams and Radix Sanguisorbae 80 grams.
The preparation method of the Chinese medicine composition of the treatment empyrosis of the present embodiment may further comprise the steps:
1), with the raw material components of above-mentioned weight portion meter, clean, the rear mixing that is ground into powder after drying can obtain powdery product;
2), in step 1) to add weight in the powdery product that obtains be 100 times Oleum sesami of raw material components weight, namely gets the paste product after the stirring;
Wherein, the granularity after powder grinds is 100 orders.
Should be noted that at last: above embodiment is only in order to illustrate that technical scheme of the present invention is not intended to limit; although with reference to above-described embodiment the present invention is had been described in detail; those of ordinary skill in the field are to be understood that: the technical staff reads after the present specification still and can make amendment or be equal to replacement the specific embodiment of the present invention, but these modifications or change all do not break away from the claim protection domain that the present patent application awaits the reply.

Claims (7)

1. Chinese medicine composition for the treatment of empyrosis is characterized in that described compositions is prepared from by the Chinese crude drug that by weight following raw materials according component forms:
Gypsum Fibrosum 25-50, Mirabilitum crystallina 50-70, Olibanum 30-70, Myrrha 45-60, Radix Et Rhizoma Rhei 40-60, catechu 50-80.
2. the Chinese medicine composition of empyrosis according to claim 1 is characterized in that the product forms that described compositions is prepared is paste, Powdered and liquid preparation.
3. the Chinese medicine composition of empyrosis according to claim 1 is characterized in that described compositions comprises that weight is the 1-100 Oleum sesami doubly of raw material components weight.
4. method for preparing the Chinese medicine composition of empyrosis claimed in claim 1 may further comprise the steps:
With above-mentioned raw material components by weight, to clean, the rear mixing that is ground into powder after drying can obtain powdery product.
5. method for preparing the Chinese medicine composition of empyrosis claimed in claim 1 may further comprise the steps:
With above-mentioned raw material components by weight, clean, the rear mixing that is ground into powder after drying, adding weight in the powdery product that obtains is the 1-100 Oleum sesami doubly of raw material components weight, namely gets the paste product after the stirring.
6. method for preparing the Chinese medicine composition of empyrosis claimed in claim 1 may further comprise the steps:
With above-mentioned raw material components by weight, clean, rear mixing is ground into powder after drying, adding 1-10 water doubly in the powdery product that obtains makes the water that adds can cover raw material components, then under 50-100 ℃ of temperature, boil 10-120 minute after, cold filtration namely gets liquid preparation.
7. the preparation method of the Chinese medicine composition of arbitrary described empyrosis according to claim 4-6 is characterized in that the granularity after described powder grinds is the 10-150 order.
CN 201010512646 2010-10-20 2010-10-20 Traditional Chinese medicinal composition for treating burns and scalds and preparation method thereof Expired - Fee Related CN102451257B (en)

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CN103007034B (en) * 2012-12-06 2014-07-09 于凤娜 Traditional Chinese medicine composition used for treatment of residual second-degree burn wound, and preparation method thereof
CN106266464A (en) * 2016-11-17 2017-01-04 李世全 A kind of Chinese medicine composition treating scald or burn and its preparation method and application
CN107669926A (en) * 2017-10-19 2018-02-09 王守文 Burned muscle reproducing dissipates
CN111991471A (en) * 2020-10-12 2020-11-27 潍坊爱松堂医药科技有限公司 A topical Chinese medicinal preparation for treating knife wound, burn and scald, and its preparation method

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