CN102429767A - Laser cornea hot forming surgery system - Google Patents

Laser cornea hot forming surgery system Download PDF

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Publication number
CN102429767A
CN102429767A CN2011102461935A CN201110246193A CN102429767A CN 102429767 A CN102429767 A CN 102429767A CN 2011102461935 A CN2011102461935 A CN 2011102461935A CN 201110246193 A CN201110246193 A CN 201110246193A CN 102429767 A CN102429767 A CN 102429767A
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laser
cornea
scanning
spectroscope
human eye
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CN2011102461935A
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CN102429767B (en
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周传清
王纬超
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GUANGDONG FORTUNE NEWVISION TECHNOLOGY Ltd
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SUZHOU XINSHIYE PHOTOELECTRIC TECHNOLOGY Co Ltd
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Abstract

The invention discloses a laser cornea hot forming surgery system, which comprises a laser and a collimating, scanning and focusing system thereof, wherein a first spectroscope is arranged in front of a human eye; the reflecting light path of the first spectroscope is provided with a second spectroscope, a third spectroscope and a surgical microscope in sequence; the reflecting light paths of the second and third spectroscopes are provided with a cornea topographic apparatus and an eye movement tracking system respectively; the laser cornea hot forming surgery system is further provided with an ultraviolet light source; the emitting light path of the ultraviolet light source is over against the focusing treatment position of the laser and the collimating, scanning and focusing system thereof in the human eye; and the ultraviolet light source is used for irradiating the cornea after lactoflavin is dripped after the completion of a laser cornea hot forming surgery to induce crosslinking modification of cornea collagen. By adopting the laser cornea hot forming surgery system, the surgical heating uniformity and the treatment effect are enhanced remarkably, the postoperative diopter and cornea form are more stable simultaneously, and the postoperative cornea regression is relieved effectively.

Description

The laser thermal keratoplasty system
Technical field
The present invention relates to a kind of laser equipment, relate in particular to a kind of laser thermo keratoplasty surgical apparatus.
Background technology
Hypermetropia (presbyopia) is ametropia and a dysregulation common in the human eye, and along with the raising of quality of the life, people more and more become focus social and that ophthalmic industry is paid close attention to its understanding and treatment.Tradition hypermetropia (presbyopia) antidote is to wear glasses, and new approach has been opened up in its treatment that develops into of laser medicine technology.Laser thermal keratoplasty shrinks its collagen fiber through the heating of corneal substrate, thereby changes the diopter of cornea, is a kind of non-invasion formula laser therapy hypermetropia (presbyopia) means that have prospect.Clinical research shows that present laser thermal keratoplasty postoperative complications of regression is obvious, and has some cases irregular astigmatism to occur, secular dioptric effect and the stable requirement that can not well reach the patient.Therefore, also need to improve the postoperative quality, avoid owing rectifying and complications of regression through further studying.
Find through the document retrieval; Similar number of patent application is 200610118896.9 patent " the live body surgery systems of scanning type laser thermokeratoplasty ", and this patent utilization scan laser source almost is heated cornea simultaneously, though increased the predictability and the stability of operation; But because the influence of body reparation and environmental change; Post-operative cornea is irregular to be increased with higher order aberratons, and complications of regression obviously causes bad visual quality, has a strong impact on surgical effect.
Summary of the invention
Technical problem to be solved by this invention is in order to overcome the deficiency of prior art and equipment; A kind of laser cornea thermoforming art system is provided, makes had significantly by thermal uniformity and therapeutic effect to improve, simultaneously; Postoperative diopter and cornea form are more stable, effectively alleviate the post-operative cornea complications of regression.
The present invention is that to solve the problems of the technologies described above the technical scheme of employing following:
A kind of laser thermal keratoplasty system comprises a laser instrument and collimated scanning focusing system thereof, is responsible for laser focusing to human eye is undergone surgery; Between described laser instrument and collimated scanning focusing system and human eye, be provided with first spectroscope; On the light path of first spectroscopical reflection human eye backscatter signals, be disposed with second spectroscope, the 3rd spectroscope and operating microscope, described operating microscope is used to observe the whole surgery process;
On the light path of said second, third spectroscopical reflection human eye backscatter signals, be respectively arranged with corneal topographer and eye movement tracking system, described corneal topographer links to each other with the PC controlling platform with the eye movement tracking system; Described corneal topographer corneal diopter detects in real time, and described eye movement tracking system is carried out track and localization to pupil center, and both detections and positioning result are sent to described PC controlling platform real-time feedback adjustment is carried out in operation;
Described laser thermal keratoplasty system also is provided with ultraviolet source; The emitting light path of said ultraviolet source is over against the position of laser instrument and collimated scanning focusing system focusing therapy in human eye thereof; Said ultraviolet source be responsible for behind thermokeratoplasty, splashing into earlier riboflavin again corneal shine, it is cross-linking modified to induce corneal collagen to take place.
Described laser instrument is the continuous wave laser of wave-length coverage in the 1.75-2.22 micron.
Described collimated scanning focusing system comprises collimator, light path scanning system and condenser lens; The light beam that said laser instrument sends becomes directional light through described collimating device collimation; Scanning through described light path scanning system realization laser beam focuses on human eye through described condenser lens more again.
Described light path scanning system is an XY 2-D vibration mirror scanning system.
Described laser instrument is preferably 1.94 microns continuous wave lasers.
Said corneal topographer is responsible for detecting in real time with corneal topography diagram form corneal diopter, and the result is sent to the PC controlling platform.
Said eye movement tracking system is responsible for the track and localization to pupil center, and eyeball is mobile at random in effectively preventing to perform the operation, and makes laser and eyeball static relatively all the time, and its result is sent to the PC controlling platform.
The positioning result that said PC controlling platform is responsible for receiving the testing result and the eye movement tracking system of corneal topographer carries out real-time feedback adjustment to operation.
Said operating microscope is responsible for observing the whole surgery process, is convenient to adjust the position of human eye.
Said ultraviolet source be responsible for behind thermokeratoplasty, splashing into earlier riboflavin again corneal shine, it is cross-linking modified to induce corneal collagen to take place.
The present invention has following advantage: 1, use the continuous wave laser of wave-length coverage in the 1.75-2.22 micron, cornea is significantly improved by thermal uniformity and therapeutic effect.2, the whole surgery process is by computer control, and operating time is short, improves the stability of cornea hot forming effect, and operation receives thermal uniformity and therapeutic effect that raising is significantly arranged.3, can monitor operation process in real time and make suitable adjustment to reach optimized surgical effect.4, make corneal collagen cross-linking modified through riboflavin-ultraviolet, postoperative diopter and cornea form are more stable, effectively alleviate postoperative complications of regression phenomenon.
Description of drawings
For let above-mentioned purpose of the present invention, feature and advantage can be more obviously understandable, elaborate below in conjunction with the accompanying drawing specific embodiments of the invention, wherein:
Fig. 1 is the structural representation of laser thermal keratoplasty of the present invention system.
Among the figure:
1, laser instrument and collimated scanning focusing system 2 thereof, beam splitting system 3, corneal topographer
4, eye movement tracking system 5, PC controlling platform 6, operating microscope
7, ultraviolet source 8,9,1.94 microns continuous wave lasers of human eye
10, collimator 11, XY 2-D vibration mirror scanning system 12, condenser lens
13, first spectroscope 14, second spectroscope 15, the 3rd spectroscope.
The specific embodiment
Fig. 1 shows a kind of laser thermal keratoplasty system; Comprise a laser instrument and collimated scanning focusing system 1 thereof; Be responsible for laser focusing to human eye 8 is undergone surgery; Wherein said laser instrument is 1.94 microns continuous wave lasers 9 (also can be the continuous wave laser of wave-length coverage in the 1.75-2.22 micron, because the optical maser wavelength that this continuous wave laser sends has the superiority of cornea hot forming operation); Described collimated scanning focusing system comprises collimator 10, XY 2-D vibration mirror scanning system 11 and condenser lens 12; The light beam that said 1.94 microns continuous wave lasers 9 send is collimated into directional light through described collimator 10; Realize the scanning of laser beam through described XY 2-D vibration mirror scanning system 11; Again focus on human eye 8 through described condenser lens 12 again; Certainly wherein XY 2-D vibration mirror scanning system 11 also can be that other prior art is in the light path scanning system, as long as can accomplish the scanning of laser beam according to the operation demand.
Between described laser instrument and collimated scanning focusing system 1 and human eye, be provided with first spectroscope 13; On the human eye optical signal reflected light path of first spectroscope 13, be disposed with second spectroscope 14, the 3rd spectroscope 15 and operating microscope 6, described operating microscope 6 is used to observe the whole surgery process;
On the human eye optical signal reflected light path of said second, third spectroscope 14,15, be respectively arranged with corneal topographer 3 and eye movement tracking system 4, described corneal topographer 3 links to each other with PC controlling platform 5 with eye movement tracking system 4; Described corneal topographer 3 corneal diopters detect in real time, and 4 pairs of pupil center of described eye movement tracking system carry out track and localization, and both detections and positioning result are sent to 5 pairs of operations of described PC controlling platform and carry out real-time feedback adjustment;
Wherein, Said first spectroscope 13, second spectroscope 14 and the 3rd spectroscope 15 constitute beam splitting systems 2; First spectroscope 13 is responsible for the light that human eye penetrates is assigned to operating microscope 6; Second spectroscope 14 is responsible for that the light that human eye penetrates is assigned to corneal topographer 3, the three spectroscopes 15 and is responsible for the light that human eye penetrates is assigned to eye movement tracking system 4.
Described laser thermal keratoplasty system also is provided with ultraviolet source 7; The emitting light path of said ultraviolet source 7 is over against the position of laser instrument and collimated scanning focusing system 1 focusing therapy in human eye 8 thereof; Said ultraviolet source 7 be responsible for behind thermokeratoplasty, splashing into earlier riboflavin again corneal shine, it is cross-linking modified to induce corneal collagen to take place.
The present invention realizes the hot forming art treatment to eye cornea through described laser instrument and collimated scanning focusing system 1 thereof; Said corneal topographer 3 is carried out online in real time through second spectroscope, 14 corneal diopters and is detected; Said eye movement tracking system 4 is carried out track and localization through 15 pairs of pupil center of the 3rd spectroscope; Both detections and positioning result are sent to 5 pairs of operations of PC controlling platform and carry out real-time feedback adjustment; Said operating microscope 6 is used to observe the whole surgery process, splash into after the corneal hot forming riboflavin re-use said ultraviolet source 7 radiation-induced corneal collagens take place cross-linking modified, thereby accomplish stable, efficient laser cornea thermoforming art.

Claims (3)

1. a laser thermal keratoplasty system is characterized in that: comprise a laser instrument and collimated scanning focusing system thereof, be responsible for laser focusing to human eye is undergone surgery; Between described laser instrument and collimated scanning focusing system and human eye, be provided with first spectroscope; On the light path of first spectroscopical reflection human eye backscatter signals, be disposed with second spectroscope, the 3rd spectroscope and operating microscope, described operating microscope is used to observe the whole surgery process;
On the light path of said second, third spectroscopical reflection human eye backscatter signals, be respectively arranged with corneal topographer and eye movement tracking system, described corneal topographer links to each other with the PC controlling platform with the eye movement tracking system; Described corneal topographer corneal diopter detects in real time, and described eye movement tracking system is carried out track and localization to pupil center, and both detections and positioning result are sent to described PC controlling platform real-time feedback adjustment is carried out in operation;
Described laser thermal keratoplasty system also is provided with ultraviolet source; The emitting light path of said ultraviolet source is over against the position of laser instrument and collimated scanning focusing system focusing therapy in human eye thereof; Said ultraviolet source be responsible for behind thermokeratoplasty, splashing into earlier riboflavin again corneal shine, it is cross-linking modified to induce corneal collagen to take place;
Described laser instrument is the continuous wave laser of wave-length coverage in the 1.75-2.22 micron;
Described collimated scanning focusing system comprises collimator, light path scanning system and condenser lens; The light beam that said laser instrument sends becomes directional light through described collimating device collimation; Scanning through described light path scanning system realization laser beam focuses on human eye through described condenser lens more again.
2. laser thermal keratoplasty according to claim 1 system, it is characterized in that: described light path scanning system is an XY 2-D vibration mirror scanning system.
3. laser thermal keratoplasty according to claim 1 and 2 system, it is characterized in that: described laser instrument is 1.94 microns continuous wave lasers.
CN201110246193.5A 2011-08-25 2011-08-25 Laser cornea hot forming surgery system Expired - Fee Related CN102429767B (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104853700A (en) * 2012-10-17 2015-08-19 阿尔贝特·达克瑟尔 Device and method for irradiating the eye
CN105498097A (en) * 2015-12-23 2016-04-20 济南三维医疗器械有限公司 Corneal cross-linking instrument
CN106621063A (en) * 2016-12-23 2017-05-10 中国科学院苏州生物医学工程技术研究所 Riboflavin UV cross-bonding device with eyeball position real time tracking
CN106693205A (en) * 2016-12-23 2017-05-24 中国科学院苏州生物医学工程技术研究所 Riboflavin UV cross-linking system
CN109481142A (en) * 2018-12-18 2019-03-19 深圳先进技术研究院 A kind of Terahertz thermokeratoplasty system and method
WO2020125435A1 (en) * 2018-12-18 2020-06-25 深圳先进技术研究院 Terahertz thermokeratoplasty system and method
CN114515223A (en) * 2020-11-18 2022-05-20 瑞雅医疗器械(上海)有限公司 Laser ophthalmology equipment

Citations (6)

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WO1992015034A1 (en) * 1991-02-19 1992-09-03 Phoenix Laser Systems, Inc. Target movement compensation for laser surgical system
CN2317809Y (en) * 1997-10-09 1999-05-12 深圳市医用电子仪器厂 Eyeball-cornea topographical instrument
CN1268340A (en) * 1999-03-10 2000-10-04 路易斯·安东尼奥·鲁伊兹 Reciprocal type correction operation system using topography and laser system interface
WO2010015356A1 (en) * 2008-08-04 2010-02-11 Carl Zeiss Vision Gmbh Systems and methods for ordering lenses
CN101810528A (en) * 2010-01-22 2010-08-25 温州医学院 Cornea center positioning method for excimer laser cornea refractive surgery
WO2011012557A1 (en) * 2009-07-27 2011-02-03 Sanseverino, Renato Ophthalmic solution for protecting internal structures of the eyeball against uv-a rays or for the treatment of keratoconus with a trans-epithelial cross-linking technique

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992015034A1 (en) * 1991-02-19 1992-09-03 Phoenix Laser Systems, Inc. Target movement compensation for laser surgical system
CN2317809Y (en) * 1997-10-09 1999-05-12 深圳市医用电子仪器厂 Eyeball-cornea topographical instrument
CN1268340A (en) * 1999-03-10 2000-10-04 路易斯·安东尼奥·鲁伊兹 Reciprocal type correction operation system using topography and laser system interface
WO2010015356A1 (en) * 2008-08-04 2010-02-11 Carl Zeiss Vision Gmbh Systems and methods for ordering lenses
WO2011012557A1 (en) * 2009-07-27 2011-02-03 Sanseverino, Renato Ophthalmic solution for protecting internal structures of the eyeball against uv-a rays or for the treatment of keratoconus with a trans-epithelial cross-linking technique
CN101810528A (en) * 2010-01-22 2010-08-25 温州医学院 Cornea center positioning method for excimer laser cornea refractive surgery

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104853700A (en) * 2012-10-17 2015-08-19 阿尔贝特·达克瑟尔 Device and method for irradiating the eye
CN105498097A (en) * 2015-12-23 2016-04-20 济南三维医疗器械有限公司 Corneal cross-linking instrument
CN105498097B (en) * 2015-12-23 2017-11-17 济南三维医疗器械有限公司 A kind of corneal cross-linking instrument
CN106621063A (en) * 2016-12-23 2017-05-10 中国科学院苏州生物医学工程技术研究所 Riboflavin UV cross-bonding device with eyeball position real time tracking
CN106693205A (en) * 2016-12-23 2017-05-24 中国科学院苏州生物医学工程技术研究所 Riboflavin UV cross-linking system
CN106693205B (en) * 2016-12-23 2019-04-19 中国科学院苏州生物医学工程技术研究所 The online structure of riboflavin ultraviolet glue
CN106621063B (en) * 2016-12-23 2019-05-14 中国科学院苏州生物医学工程技术研究所 Riboflavin ultraviolet glue coupling device with eyeball position real-time tracing
CN109481142A (en) * 2018-12-18 2019-03-19 深圳先进技术研究院 A kind of Terahertz thermokeratoplasty system and method
WO2020125435A1 (en) * 2018-12-18 2020-06-25 深圳先进技术研究院 Terahertz thermokeratoplasty system and method
CN109481142B (en) * 2018-12-18 2023-08-22 深圳先进技术研究院 Terahertz cornea thermal forming system and method
CN114515223A (en) * 2020-11-18 2022-05-20 瑞雅医疗器械(上海)有限公司 Laser ophthalmology equipment

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