CN102421894A - 用于促进局部缺血性和糖尿病性创面愈合的组合物、试剂盒和方法 - Google Patents

用于促进局部缺血性和糖尿病性创面愈合的组合物、试剂盒和方法 Download PDF

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Publication number
CN102421894A
CN102421894A CN201080019437XA CN201080019437A CN102421894A CN 102421894 A CN102421894 A CN 102421894A CN 201080019437X A CN201080019437X A CN 201080019437XA CN 201080019437 A CN201080019437 A CN 201080019437A CN 102421894 A CN102421894 A CN 102421894A
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CN
China
Prior art keywords
wound
sdf
selectin
diabetic
compsn
Prior art date
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Pending
Application number
CN201080019437XA
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English (en)
Chinese (zh)
Inventor
O·C·維拉斯奎茲
Z-J·刘
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University of Miami
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University of Miami
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Application filed by University of Miami filed Critical University of Miami
Publication of CN102421894A publication Critical patent/CN102421894A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056—Lectin superfamily, e.g. CD23, CD72
    • C07K14/70564—Selectins, e.g. CD62
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/195—Chemokines, e.g. RANTES
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Physiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201080019437XA 2009-04-21 2010-04-09 用于促进局部缺血性和糖尿病性创面愈合的组合物、试剂盒和方法 Pending CN102421894A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17127109P 2009-04-21 2009-04-21
US61/171,271 2009-04-21
PCT/US2010/030471 WO2010123699A2 (en) 2009-04-21 2010-04-09 Compositions, kits and methods for promoting ischemic and diabetic wound healing

Publications (1)

Publication Number Publication Date
CN102421894A true CN102421894A (zh) 2012-04-18

Family

ID=43011688

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201080019437XA Pending CN102421894A (zh) 2009-04-21 2010-04-09 用于促进局部缺血性和糖尿病性创面愈合的组合物、试剂盒和方法

Country Status (6)

Country Link
US (1) US20120058086A1 (https=)
EP (1) EP2421967A4 (https=)
JP (1) JP2012524781A (https=)
KR (1) KR20120023633A (https=)
CN (1) CN102421894A (https=)
WO (1) WO2010123699A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106581068A (zh) * 2016-11-08 2017-04-26 广州医科大学附属第三医院 一种可以快速恢复皮肤创面的生物膜及其制备方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016516071A (ja) * 2013-03-15 2016-06-02 ユベンタス セラピューティクス，インコーポレイテッド 瘢痕形成を軽減するためのｓｄｆ−１の使用
EP3237622B1 (en) * 2014-12-23 2021-02-24 Ilya Pharma AB Methods for wound healing
WO2016149632A1 (en) * 2015-03-18 2016-09-22 Bio1 Systems, Llc Digital wound assessment device and method
CN110769861A (zh) * 2017-05-02 2020-02-07 迈阿密大学 治疗缺血性组织的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008118370A2 (en) * 2007-03-22 2008-10-02 The Trustees Of The University Of Pennsylvania Hyperbaric treatment in wound healing

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070244043A1 (en) * 2005-03-10 2007-10-18 Novavax, Inc. Recombinant E-selectin made in insect cells

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008118370A2 (en) * 2007-03-22 2008-10-02 The Trustees Of The University Of Pennsylvania Hyperbaric treatment in wound healing

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHEN ET AL: "Combination of VEGF165/Angiopoietin-1 gene and endothelial progenitor cells for therapeutic neovascularization", 《EUROPEAN JOURNAL OF PHARMACOLOGY》 *
IL-YOUNG OH ET AL: "Involvement of E-selectin in recruitment of endothelial progenitor cells and angiogenesis in ischemic muscle", 《BLOOD》 *
NISHIWAKI ET AL: "Endothelial E-Selectin Potentiates Neovascularization via Endothelial Progenitor Cell-Dependent and -Independent Mechanisms", 《ARTERIOSCLER THROMB VASC BIOL》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106581068A (zh) * 2016-11-08 2017-04-26 广州医科大学附属第三医院 一种可以快速恢复皮肤创面的生物膜及其制备方法

Also Published As

Publication number Publication date
EP2421967A2 (en) 2012-02-29
KR20120023633A (ko) 2012-03-13
WO2010123699A2 (en) 2010-10-28
EP2421967A4 (en) 2013-01-02
JP2012524781A (ja) 2012-10-18
WO2010123699A3 (en) 2011-01-06
US20120058086A1 (en) 2012-03-08

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Application publication date: 20120418