CN102397528B - 一种治疗鸡传染性贫血的复方蜂胶组合物及其制备方法 - Google Patents
一种治疗鸡传染性贫血的复方蜂胶组合物及其制备方法 Download PDFInfo
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- CN102397528B CN102397528B CN2011103606490A CN201110360649A CN102397528B CN 102397528 B CN102397528 B CN 102397528B CN 2011103606490 A CN2011103606490 A CN 2011103606490A CN 201110360649 A CN201110360649 A CN 201110360649A CN 102397528 B CN102397528 B CN 102397528B
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Abstract
一种治疗鸡传染性贫血的复方蜂胶组合物及其制备方法，涉及动物医药领域。该组合物制备方法如下：(1)将组方中的各种成分(干扰素除外)分别超微粉碎后过700目筛；(2)按重量称取蜂胶15-35份、鸡用干扰素5-20份、枸杞10-35份、当归15-30份，混合5-10分钟至均匀；(3)按重量称取熟地黄10-30份、柴胡10-30份、大青叶15-45份、赤芍10-35份，混合5-10分钟至均匀；(4)合并上述(2)、(3)步骤制得的组合物，继续混合10-15分钟至均匀即成。本发明的有益效果是：组方合理，制备简单，该组合物无毒副作用、超微粉碎、生物利用度高，临床证明对治疗鸡传染性贫血有特效。
Description
一种治疗鸡传染性贫血的复方蜂胶组合物及其制备方法
技术领域
[0001] 本发明涉及动物医药领域，特别涉及一种治疗鸡传染性贫血的复方蜂胶组合物及其制备方法。
背景技术
[0002] 鸡传染性贫血是由鸡传染性贫血病毒引起的一种主要侵害雏鸡为主的免疫抑制性和蛋传性传染病，以再生障碍性贫血和全身淋巴组织萎缩为主要特征。各种龄期及品种的鸡均可感染，病死率一般为5% -60%之间，可影响家禽的生长和产蛋性能。该病一年四季均可发生,是危害养鸡业的主要疾病之一。
[0003] 本病的病原体是鸡传染性贫血病毒,病毒对外界的抵抗力很强。该病几乎遍布世界所有养鸡国家，分布十分广泛。目前，防治该病最常用的是抗病毒中药和西药，中药由于其组方不合理或只是简单的粉碎，粒径过大，药物释放较慢，导致其生物利用度较低，临床效果不是很好；而各种抗病毒药物如利巴韦林、金刚烷胺等农业部已经禁止使用。
[0004] 因此研发一种治疗鸡传染性贫血的无药物残留、无耐药性产生、临床效果显著的特效药物是该领域科研技术人员急待解决的新课题之一。 发明内容
[0005] 本发明的目的在于克服上述不足之处，提供一和组方合理、制备简单、超微粉碎、生物利用度高、效果明显、无耐药性和药物残留的有效治疗鸡传染性贫血的复方蜂胶组合物及其制备方法。
[0006] 为实现上述目的，本发明所采用的实施方式如下:一种治疗鸡传染性贫血的复方蜂胶组合物，由以下组分按重量份数混合配制而成:蜂胶15-35份、鸡用干扰素5-20份、枸杞10-35份、当归15-30份、熟地黄10-30份、柴胡10-30份、大青叶15-45份、赤芍10-35份。
[0007] 所述各种组分优选配比量为:蜂胶30份、鸡用干扰素10份、枸杞25份、当归20份、熟地黄20份、柴胡20份、大青叶30份、赤芍25份。
[0008] 一种治疗鸡传染性贫血的复方蜂胶组合物的制备方法，按如下步骤进行:
[0009] (I)将组方中的各种成分(干扰素除外)分别超微粉碎后过700目筛；
[0010] (2)按重量称取蜂胶15-35份、鸡用干扰素5-20份、枸杞10-35份、当归15-30份，混合5-10分钟至均匀；
[0011] (3)按重量称取熟地黄10-30份、柴胡10-30份、大青叶15-45份、赤芍10-35份，混合5-10分钟至均匀；
[0012] (4)合并上述(2)、(3)步骤制得的组合物，继续混合10-15分钟至均匀即成。
[0013] 各组分的药物特性如下:
[0014] 蜂胶:苦、辛、寒，归脾、胃经，具有抗菌消炎、止痛止痒、促进组织再生、提高免疫力、抗过敏氧化、止血、保护胃肠粘膜的功能。[0015] 干扰素:是一种广谱抗病毒剂，对RNA和DNA病毒都有抑制或杀灭作用；可以诱导肿瘤细胞凋亡，从而杀灭肿瘤细胞；干扰素对体液免疫、细胞免疫、巨噬细胞及NK细胞均有免疫增强作用。
[0016] 枸杞:甘、平，归肝、肾经，具有补益肝肾、益精明目的功能；主治肝肾阴虚、腰肢无力等。
[0017] 当归:甘、辛、温，归肝、心、脾经，具有补血养血、活血止痛、润燥通便的功能；主治血虚劳伤、血瘀疼痛、跌打损伤、痈肿疮疡、肠燥便秘等。
[0018] 熟地黄:甘、微温，归肝、肾经，具有滋阴补血、益精填髓的功能；主治肝肾阴虚、血虚精亏、腰胯痿软、虚喘久咳、虚热盗汗等。
[0019] 柴胡:辛、苦、微寒，归肝、胆、肺经，具有发表和里、升举阳气、疏肝解郁的功能；主治感冒发热、寒热往来、脾虚久泻等。
[0020] 大青叶:苦、寒，归心、胃经，具有清热解毒、凉血消斑的功能；主治热病发斑、咽喉肿痛、热痢、黄疸、痈肿、丹毒等。
[0021] 赤芍:苦、微寒，归肝经，具有清热凉血、散瘀止痛的功能；主治温毒发斑、肠热下血、目赤肿痛、膝肿疮瘍、跌打损伤等。
[0022] 以上诸味中药按照中医药理论配伍组合，针对鸡传染性贫血的致病微生物和临床症状及病理变化，发挥标本兼治的作用。
[0023] 本发明的有益效果是: 组方合理，制备简单，分步混合更加均匀；中药组合物无污染、无药残、无耐药性，成本低，取材广，超微粉碎、生物利用度高，即可拌料也可饮水，疗效非常显著。本发明按照中兽医传统理论，优选出该七味中药，并使它们按照优选配比组成纯中药散剂，临床应用证明，对治疗鸡传染性贫血有特效，并且使其产品肉质达到无公害要求，满足产品的出口标准，有效保证了人们的身体健康。
具体实施方式
[0024] 以下结合较佳实施例，对依据本发明提供的具体实施方式详述如下:
[0025] 实施例1
[0026] 一种治疗鸡传染性贫血的复方蜂胶组合物及其制备方法:按如下步骤进行:(每份按IOg计)
[0027] (I)将组方中的各种成分(干扰素除外)分别超微粉碎后过700目筛；
[0028] (2)按重量称取蜂胶150份、鸡用干扰素50份、枸杞100份、当归150份，混合5_10分钟至均匀；
[0029] (3)按重量称取熟地黄100份、柴胡100份、大青叶150份、赤芍100份，混合5_10分钟至均匀；
[0030] (4)合并上述(2)、(3)步骤制得的组合物，继续混合10-15分钟至均匀即成。
[0031] 实施例2
[0032] 一种治疗鸡传染性贫血的复方蜂胶组合物及其制备方法:按如下步骤进行:(每份按IOg计)
[0033] (I)将组方中的各种成分(干扰素除外)分别超微粉碎后过700目筛；
[0034] (2)按重量称取蜂胶250份、鸡用干扰素100份、枸杞250份、当归200份，混合5-10分钟至均匀；
[0035] (3)按重量称取熟地黄200份、柴胡200份、大青叶300份、赤芍250份，混合5_10分钟至均匀；
[0036] (4)合并上述(2)、(3)步骤制得的组合物，继续混合10-15分钟至均匀即成。
[0037] 实施例3
[0038] 一种治疗鸡传染性贫血的复方蜂胶组合物及其制备方法:按如下步骤进行:(每份按IOg计)
[0039] (I)将组方中的各种成分(干扰素除外)分别超微粉碎后过700目筛；
[0040] (2)按重量称取蜂胶350份、鸡用干扰素200份、枸杞350份、当归300份，混合5-10分钟至均匀；
[0041] (3)按重量称取熟地黄300份、柴胡300份、大青叶450份、赤芍350份，混合5_10分钟至均匀；
[0042] (4)合并上述(2)、(3)步骤制得的组合物，继续混合10-15分钟至均匀即成。
[0043] 临床试验:
[0044] 将本发明产品喂食患病家禽等，日服用量为:按本发明每100g，拌料120kg饲喂，饮水200kg，每日2-3次，连用3-5日；口服后通过胃肠道吸收达到治疗疾病的目的。
[0045] 表是本发明与其它药物治疗鸡传染性贫血的田间应用情况对比:·[0046]
[0047] 本次临床结果经统计分析，本发明组合物治疗组与鸡传染性贫血散组在治愈率方面相比差异极显著(P <0.01)。
[0048] 上述参照实施例对该治疗鸡传染性贫血的复方蜂胶组合物及其制备方法进行的详细描述，是说明性的而不是限定性的，可按照所限定范围列举出若干个实施例，因此在不脱离本发明总体构思下的变化和修改，应属本发明的保护范围之内。
Claims (3)
1.一种治疗鸡传染性贫血的复方蜂胶组合物，其特征是由以下组分按重量份数混合配制而成:蜂胶15-35份、鸡用干扰素5-20份、枸杞10-35份、当归15-30份、熟地黄10-30份、柴胡10-30份、大青叶15-45份、赤芍10-35份。
2.根据权利要求1所述的治疗鸡传染性贫血的复方蜂胶组合物，其特征是所述各种组分优选配比量为:蜂胶30份、鸡用干扰素10份、枸杞25份、当归20份、熟地黄20份、柴胡20份、大青叶30份、赤芍25份。
3.一种根据权利要求1所述的治疗鸡传染性贫血的复方蜂胶组合物的制备方法，其特征是按如下步骤进行: (1)将组方中的各种成分(干扰素除外)分别超微粉碎后过700目筛； (2)按重量称取取蜂胶15-35份、鸡用干扰素5-20份、枸杞10-35份、当归15-30份，混合5-10分钟至均匀； (3)按重量称取熟地黄10-30份、柴胡10-30份、大青叶15-45份、赤芍10-35份，混合·5-10分钟至均匀； (4)合并上述(2)·、(3)步骤制得的组合物，继续混合10-15分钟至均匀即成。
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