CN102389463A - Traditional Chinese medicine for treating diabetic diarrhea - Google Patents
Traditional Chinese medicine for treating diabetic diarrhea Download PDFInfo
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Abstract
Description
技术领域 technical field
本发明属于治疗糖尿病的中药领域。 The invention belongs to the field of traditional Chinese medicine for treating diabetes.
背景技术 Background technique
糖尿病性腹泻系糖尿病并发的肠微血管病变和神经病变所致。在糖尿病患者中并不少见。由于抗生素对此无效,该病极为难治。现在的用于治疗糖尿病性腹泻的中药,存在两方面的不足:一是效果不够明显,二是见效比较迟缓,以致大批该病患者长年腹泻不止,非常痛苦。 Diabetic diarrhea is caused by intestinal microangiopathy and neuropathy complicated by diabetes. It is not uncommon in diabetic patients. The disease is extremely difficult to treat because antibiotics are ineffective. Present Chinese medicine for the treatment of diabetic diarrhea has two deficiencies: the one is that the effect is not obvious enough, and the other is that the effect is relatively slow, so that a large number of patients with this disease have persistent diarrhea and are very miserable.
针对以上提出的问题,本发明提供一种治疗糖尿病性腹泻的中药,它能解决以往治疗中效果不够明显,见效比较迟缓的问题,效果好、见效快,具有效果显著,药效确切,见效较快的优点。 In view of the problems raised above, the present invention provides a traditional Chinese medicine for the treatment of diabetic diarrhea, which can solve the problem that the effect in the previous treatment is not obvious enough, and the effect is relatively slow. The advantage of being fast.
发明内容 Contents of the invention
本发明是通过以下技术方案来实现的: The present invention is achieved through the following technical solutions:
1、一种治疗糖尿病性腹泻的中药,采用中药原料制备,中药原料的重量配比为: 1, a kind of Chinese medicine for treating diabetic diarrhea, adopts Chinese medicine raw material to prepare, and the weight ratio of Chinese medicine raw material is:
连翘4——12份 诃子3——9份 灵芝6——18份 Forsythia 4—12 parts Myrobalan 3—9 parts Ganoderma lucidum 6—18 parts
三七1——3份 肉豆蔻3——9份 当归6——18份 Notoginseng 1—3 parts Nutmeg 3—9 parts Angelica 6—18 parts
丹参6——18份 Danshen 6——18 parts
这种治疗糖尿病性腹泻的中药是由下列方法制成的: This traditional Chinese medicine for treating diabetic diarrhea is made by the following method:
(1)按上述重量比,将连翘、诃子、灵芝、肉豆蔻、当归、丹参经常规水提取工艺提取,制成浸膏,烘干粉碎,得提取物细粉; (1) Extract forsythia, chebula, ganoderma, nutmeg, angelica, and salvia according to the above weight ratio through conventional water extraction process to make extract, dry and pulverize to obtain fine powder of extract;
(2)按上述重量比,将三七研成细粉,与上述(1)提取物细粉混合,搅拌均匀,制成中药颗粒剂、胶囊剂、片剂。 (2) Grind notoginseng into fine powder according to the above weight ratio, mix with the fine powder of the extract from (1) above, and stir evenly to make traditional Chinese medicine granules, capsules, and tablets.
本发明根据民间传统配方,根据中医扶正培本、活血化瘀的理论,精心研制而成。我们研究认为,糖尿病患者免疫力低下,阴虚燥热,血液黏稠,肠供血不足,此为肠道发生微血管病变和神经病变的主要原因。加之并发顽固性腹泻,长年稀便不止,久不痊愈,身体已极度虚弱,正气匮乏为主要发病原因。病至中后期,不同程度地存在血瘀现象。因此,扶正、清热、止泻、活血化瘀是本发明组方的主要着眼点。方中灵芝、当归扶正培本,益气养血,增强机体免疫力,免疫力的“清除”作用使血液清洁、流动性好,肠道供血充盈,这是治疗本病的关键;伍以丹参、三七养血活血,化瘀止痛;臣以连翘疏风散热,清热解毒,消痈散结;辅以诃子涩肠止泻,下气消胀,肉豆蔻温中燥湿,健脾行气,涩肠止泻。诸药配伍,相得益彰,共奏扶正培本,益气养血,活血化瘀,涩肠止泻之功,效果好,见效快,具有效果显著,药效确切,见效较快的优点。 The present invention is elaborately developed according to the folk traditional formula and the theory of traditional Chinese medicine of strengthening the body and strengthening the body, promoting blood circulation and removing blood stasis. Our research believes that diabetic patients have low immunity, yin deficiency and dryness, thick blood, and insufficient intestinal blood supply, which are the main reasons for the occurrence of microangiopathy and neuropathy in the intestinal tract. In addition, concurrent intractable diarrhea, persistent loose stools for many years, long-term unhealed, extremely weak body, lack of righteousness is the main cause of disease. In the middle and late stages of the disease, there are blood stasis phenomena to varying degrees. Therefore, strengthening the body, clearing heat, stopping diarrhea, promoting blood circulation and removing blood stasis are the main focus of the prescription of the present invention. Ganoderma lucidum and Angelica Fuzheng Peiben in the prescription can nourish qi and blood, enhance the body's immunity, and the "clearing" effect of immunity can make the blood clean and fluid, and the intestinal blood supply is full, which is the key to the treatment of this disease; Wu Yidanshen , notoginseng nourishes blood and activates blood, removes blood stasis and relieves pain; minister uses forsythia to dispel wind and dissipate heat, clears away heat and detoxification, eliminates carbuncle and dissipates stagnation; supplemented with myrobalan to astringe intestines to stop diarrhea, lower qi and relieve swelling, nutmeg warms middle and dries dampness, strengthens spleen Promoting qi, astringent intestines to relieve diarrhea. All the medicines are compatible and complement each other. They play the functions of strengthening the body, nourishing qi and nourishing blood, promoting blood circulation and removing blood stasis, astringent intestines and antidiarrheal. The effect is good, and the effect is fast.
具体实施方式 Detailed ways
通过以下实施方式对本发明做具体说明: The present invention is specifically described by the following embodiments:
1、取以下配方(重量按克为单位): 1. Take the following formula (weight in grams):
连翘400克 诃子300克 灵芝600克 Forsythia 400 grams Myrobalan 300 grams Ganoderma lucidum 600 grams
三七100克 肉豆蔻300克 当归600克 100 grams of Panax notoginseng 300 grams of nutmeg 600 grams of angelica
丹参600克 Danshen 600 grams
按规定重量,用常规水提取工艺将连翘、诃子、灵芝、肉豆蔻、当归、丹参提取,制成提取物细粉380克,将三七研成细粉,与上述提取物细粉混合,搅拌均匀,制成细小颗粒,装入0号胶囊,制成中药胶囊1266粒,每粒胶囊内含中药细粉及提取物0.3克。 Extract Forsythia, Myrobalan, Ganoderma lucidum, nutmeg, angelica, and Danshen by conventional water extraction process according to the specified weight to make 380 grams of fine powder of the extract, grind Sanqi into fine powder, and mix with the fine powder of the above extract , stir evenly, make fine particles, pack into No. 0 capsules, and make 1266 Chinese medicine capsules, each capsule contains Chinese medicine fine powder and 0.3 grams of extract.
2、取以下配方(重量按克为单位): 2. Take the following formula (the weight is in grams):
连翘800克 诃子600克 灵芝1200克 Forsythia 800 grams Myrobalan 600 grams Ganoderma lucidum 1200 grams
三七180克 肉豆蔻600克 当归1200克 180 grams of Panax notoginseng 600 grams of nutmeg Angelica sinensis 1200 grams
丹参1200克 Danshen 1200 grams
按上述同样的方法,制成中药胶囊2466粒,每粒胶囊内含中药细粉及提取物0.3克。 By above-mentioned same method, make 2466 Chinese medicine capsules, every capsule contains Chinese medicine fine powder and extract 0.3 gram.
3、取以下配方(重量按克为单位): 3. Take the following formula (the weight is in grams):
连翘1200克 诃子900克 灵芝1700克 Forsythia 1200 grams Myrobalan 900 grams Ganoderma lucidum 1700 grams
三七300克 肉豆蔻900克 当归1700克 300 grams of Panax notoginseng 900 grams of nutmeg 1700 grams of angelica
丹参1700克 Danshen 1700 grams
按上述同样的方法,制成中药胶囊3700粒,每粒胶囊内含中药细粉及提取物0.3克。 By the above-mentioned same method, make 3700 Chinese medicine capsules, every capsule contains Chinese medicine fine powder and extract 0.3 gram.
4、取以下配方(按重量比): 4. Take the following formula (by weight ratio):
连翘4份 诃子3份 灵芝7份 4 parts of Forsythia 3 parts of Myrobalan 7 parts of Ganoderma lucidum
三七1份 肉豆蔻3份 当归7份 1 serving of panax notoginseng 3 servings of nutmeg 7 servings of angelica
丹参7份 7 servings of Danshen
按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.3克。 By the above-mentioned same method, make Chinese medicine capsule, every capsule contains Chinese medicine fine powder and extract 0.3 gram.
5、取以下配方(按重量比): 5. Take the following formula (by weight ratio):
连翘9份 诃子7份 灵芝14份 9 parts of Forsythia 7 parts of Myrobalan 14 parts of Ganoderma lucidum
三七2份 肉豆蔻7份 当归14份 2 servings of panax notoginseng 7 servings of nutmeg 14 servings of angelica
丹参14份 Salvia 14 parts
按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.3克。 By the above-mentioned same method, make Chinese medicine capsule, every capsule contains Chinese medicine fine powder and extract 0.3 gram.
临床资料:clinical information:
本发明以糖尿病性腹泻为例,经16例临床观察。选择糖尿病性腹泻为标准:糖尿病患者体质虚弱,体乏无力;腹泻时大便稀水样,或大便溏泻,不成型,1天3次以上;连续腹泻3个月以上,抗生素治疗效果不明显。如以上症状,即可确诊。在确诊观察的对象中,男性9例,女性7例,无其它严重疾病,年龄为42岁—77岁,平均年龄62.2岁。 The present invention takes diabetic diarrhea as an example, through clinical observation of 16 cases. Diabetic diarrhea is selected as the standard: Diabetic patients are weak and weak; the stool is watery or loose, not formed, more than 3 times a day; continuous diarrhea for more than 3 months, the effect of antibiotic treatment is not obvious. Such as the above symptoms, can be diagnosed. Among the confirmed observation objects, there were 9 males and 7 females, without other serious diseases, ranging in age from 42 to 77 years old, with an average age of 62.2 years.
疗效判定: Judgment of curative effect:
1、显效:体质增强,身上有劲;腹泻停止,大便成型;大便1~2天一次,排便舒服。 1. Significant effect: physical fitness is enhanced, the body is strong; diarrhea stops, and the stool is formed; the stool is once every 1 to 2 days, and the bowel movement is comfortable.
2、有效:乏力缓解,腹泻次数减少,大便半稀。 2. Effective: relieve fatigue, reduce the frequency of diarrhea, and semi-loose stool.
3、无效:病症无变化。 3. Ineffective: no change in symptoms.
临床实验时,停服其它药物和保健营养品。服用本发明具体实施方式2制作的中药胶囊,观察3个月为一个疗程。服用方法:每日2次,每次4粒胶囊,每粒胶囊内含中药细粉及提取物0.3克,饭后温开水送服,1个月后症状即有缓解,服用3个月后,症状明显改善。临床实验的16人中,显效9人,有效5人,无效2人,总有效率87.5%。 During the clinical trial, stop taking other medicines and health nutrition products. Take the Chinese medicine capsule that specific embodiment 2 of the present invention makes, observe 3 months and be a course of treatment. Dosing method: 2 times a day, 4 capsules each time, each capsule contains 0.3 grams of fine powder and extract of traditional Chinese medicine, take it with warm water after meals, the symptoms will be relieved after 1 month, and after 3 months of taking, Symptoms improved significantly. Among the 16 people in the clinical trial, 9 were markedly effective, 5 were effective, and 2 were ineffective, with a total effective rate of 87.5%.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102631412A (en) * | 2012-04-04 | 2012-08-15 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine (TCM) for treating diabetic diarrhea |
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| CN102068515A (en) * | 2010-09-16 | 2011-05-25 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treatment of diabetic diarrhea |
| CN102091176A (en) * | 2010-11-25 | 2011-06-15 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic diarrhoea |
| CN102114086A (en) * | 2010-12-13 | 2011-07-06 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic diarrhea |
| CN102114074A (en) * | 2010-12-24 | 2011-07-06 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic diarrhea |
| CN102138969A (en) * | 2010-11-18 | 2011-08-03 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic diarrhea |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102068515A (en) * | 2010-09-16 | 2011-05-25 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treatment of diabetic diarrhea |
| CN102138969A (en) * | 2010-11-18 | 2011-08-03 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic diarrhea |
| CN102091176A (en) * | 2010-11-25 | 2011-06-15 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic diarrhoea |
| CN102114086A (en) * | 2010-12-13 | 2011-07-06 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic diarrhea |
| CN102114074A (en) * | 2010-12-24 | 2011-07-06 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic diarrhea |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102631412A (en) * | 2012-04-04 | 2012-08-15 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine (TCM) for treating diabetic diarrhea |
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Application publication date: 20120328 |