CN102362933B - Sustained-release tablet-shaped cachets used for treating toothache caused by excessive internal heat - Google Patents

Sustained-release tablet-shaped cachets used for treating toothache caused by excessive internal heat Download PDF

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Publication number
CN102362933B
CN102362933B CN 201110342921 CN201110342921A CN102362933B CN 102362933 B CN102362933 B CN 102362933B CN 201110342921 CN201110342921 CN 201110342921 CN 201110342921 A CN201110342921 A CN 201110342921A CN 102362933 B CN102362933 B CN 102362933B
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China
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lamellar
medicine
medicated bag
parts
cachets
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CN 201110342921
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CN102362933A (en
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刘敏
姜正岳
付晓云
徐志强
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Liu Min
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刘敏
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Abstract

The invention discloses sustained-release tablet-shaped cachets used for treating toothache caused by excessive internal heat. The cachets comprise medicines sealed in the tablet-shaped cachets. The medicines are used for treating toothache. The medicines comprise: 10 to 20 parts of a traditional Chinese medicine extract extracted from dandelion and philippine violet herb, 1 to 5 parts of vitamin B, 1 to 3 parts of thymol, 1 to 5 parts of menthene, 1 to 5 parts of borneol, and 10 to 20 parts of alcohol. With the product provided by the invention, fast releasing and effective treating are combined, and symptoms and root causes can be treated simultaneously. The tablet-shaped cachets provided by the invention have good curative effect against toothache caused by excessive internal heat due to heat syndrome.

Description

The spacetabs type lamellar medicated bag that is used for the treatment of toothache due to pathogenic fire
Technical field the present invention relates to the external medicated bag that a kind for the treatment of is had a toothache.
It may be decayed tooth that background technology is had a toothache, and various focusing depths represented may cause by getting angry that also medicine is different.The method of existing administration comprises for oral administration and external.Topical administration is direct, takes effect the fastest.Method is exactly toward the place's medication of tooth illness, comprises directly medicine is sticked in the affected part, or stings in the tooth affected part after being stained with after liquid medicine with cotton ball.But do so both troublesome poerations, general patient is difficult for being in and oneself operates, and also easily runs off very soon because saliva causes medicine, loses drug effect, need to constantly change dressings.
Summary of the invention the present invention discloses the external medicated bag of the upper toothache due to pathogenic fire of a kind of long-time effectively treatment.
Medicated bag of the present invention comprises and is used for the treatment of the medicine of having a toothache, medicine is encapsulated between the interlayer with chemosmotic surface layer and the two-layer wrapper of bottom, form the lamellar medicated bag, the quality group of described medicine becomes: by Chinese medicine extraction liquid 10-20 part that Herba Taraxaci, Herba Violae extract, vitamin B 1-5 part, thymol 1-3 part, Oleum menthae 1-5 part, Borneolum Syntheticum 1-5 part, ethanol 10-20 part.
The fixed form of medicine in the lamellar medicated bag can adopt adsorbing material (as absorbent cotton) absorption liquid drug to fix, and perhaps adopts pulverulent material (as starch) to absorb to form granule after liquid drug to fix.The amount of the every contained liquid drug of lamellar medicated bag, proper between the 0.05-0.5 gram.
The Chinese medicine extraction liquid of described Herba Taraxaci, Herba Violae can adopt Herba Taraxaci 2-6 part, and Herba Violae 2-6 part adds water 20-40 part, through the medicinal liquid of infusion, filtration, concentrated 10-20 part of obtaining.
During use, the lamellar medicated bag is crooked and cover the tooth affected part to bottom, bite with the teeth.As improvement, resilient cartridge is also matched in the present invention.Can be after the flake bag cover the tooth affected part, cartridge on the folder of medicated bag outside surrounds the lamellar medicated bag and is fixedly clamped in the tooth affected part, saves the trouble that bites with the teeth.
Thymol of the present invention has slight paralysis effect, plays the effect of quickly alleviating pain; Mentholum, Borneolum Syntheticum have cooling sensation, play the fast pain relief effect, also have the anti-inflammation and sterilization effect simultaneously; Chinese medicine extraction liquid has the effect of clearing away heat and cooling blood, anti-inflammation detumescence; Vitamin B plays auxiliary therapeutic action; Ethanol also has lenitive effect simultaneously as solvent.Be combined with, can play rapid recovery and effectively treatment combination, the effect for the treatment of both the principal and the secondary aspects of a disease at the same time has good efficacy to treatment heat syndrome the having a toothache of causing of getting angry.And medicine is installed between two-layer infiltrative wrapper and forms the lamellar medicated bag, surrounds during use to cover the tooth affected part, bites with the teeth or clamps with cartridge, and under the infiltration of saliva, the medicine slow release out.Have easy to use, the effect that medicine effective acting time is long.Through the 30 actual uses of patient, medication after 15 minutes panesthesia effective, medication after 1 day 28 people have a toothache and obviously alleviate.
Description of drawings Fig. 1 is the schematic cross-section of lamellar medicated bag of the present invention.
Fig. 2 is the schematic diagram of the face of overlooking of lamellar medicated bag of the present invention.
Fig. 3 is the structural representation of cartridge of the present invention.
Fig. 4 is the schematic diagram that the tooth that tooth suffers from is arranged of not adding medicine to.
Fig. 5 surrounds with the lamellar medicated bag schematic diagram that covers on tooth.
Fig. 6 is the schematic diagram that presss from both sides cartridge outside the lamellar medicated bag.
Fig. 7 is the structural representation of the another kind of cartridge of the present invention.
The specific embodiment is narrated the present invention referring to accompanying drawing.
Need to prove, in Chinese medicine extraction liquid of the present invention, Herba Taraxaci, Herba Violae belong to the external application Chinese medicine commonly used of a class clearing away heat and cooling blood, anti-inflammation detumescence together, and both proportionings can arbitrarily be adjusted, and effect of the present invention is not had large impact.So its proportioning is less important.
Be below the embodiment of a kind of concrete formation of medicine of the present invention: (material forms by mass).
Choose 3 parts of Herba Taraxacis, 3 parts of Herba Violaes, chopping added 20 parts of water soakings after 3 hours, when boiling rear slow fire infusion to surplus approximately 10 parts of medicinal liquids, poured out medicinal liquid.Medicinal residues add 10 parts of water, then when boiling rear smothered with to surplus approximately 6 parts of medicinal liquids, pour out medicinal liquid.Merge the medicinal liquid of twice, filter, obtain approximately 15 parts of medicinal liquids.Vitamin B (being compound vitamin B, first grinds) is added, be dissolved in inside medicinal liquid.
With 2 parts of thymols, 3 parts of Oleum menthae, 3 parts of Borneolum Syntheticums (first grinds), being dissolved in 15 parts of ethanol becomes alcoholic solution.Ethanol can adopt the medical alcohol of 70% concentration commonly used.Again the above-mentioned Chinese medicine extraction liquid that makes is added mixing, become liquid drug of the present invention.
External medicated bag of the present invention is contained in medicine between the interlayer of two-layer wrapper of lamellar, forms lamellar medicated bag 1, as Fig. 1.Wherein 2 is bottoms of wrapper, is placed with therebetween medicine 4, as Fig. 2.Cover again surface layer 3 in the above.Surface layer can with bottom equally large or more bigger than bottom, bottom surrounding and surface layer are bonded together, with drug pack between the interlayer of bottom and surface layer.Joint method can be gluing, perhaps uses linear slit, as the linear slit 5 in figure.Bottom 2 and surface layer 3 adopt the permeable material of open structure, such as cloth matter or paper material, or the woven cloth of thin plastic wire, make saliva permeate, and make drug osmotic out.The lamellar medicated bag of finished product can be packed into and be preserved in little plastic sealing bag, avoids drug volatilization, just takes out during use.
For with the liquid drug fixing and packaging in interlayer, can adopt adsorbing material (as absorbent cotton, sponge etc.) to come the adsorptive liquid medicine, or adopt pulverulent material (as starch, dextrin, arabic gum etc.) adsorptive liquid medicine to form solid-state granule, and then be contained in interlayer.As a kind of particular form, can directly be fixed on surface layer after the adsorbing material absorption medicine by lamellar, consist of the bottom with medicine, to save technique.The amount of the liquid drug that every lamellar medicated bag comprises, proper between the 0.05-0.5 gram.
During use, lamellar medicated bag 1 is crooked and surround and cover the tooth affected part towards bottom 2, bite with the teeth, by the infiltration of saliva, make the medicine slow release out.Directly topical administration, can not run off because saliva causes medicine very soon yet, reaches the long-time effectively purpose of administration.
Flexible cartridge 6 is also matched in the present invention, as Fig. 3, helps the encirclement of lamellar medicated bag be fixed on the tooth affected part and do not bite with the teeth.7 of Fig. 4 is the teeth that have tooth to suffer from, and first 1 bending of lamellar medicated bag is covered tooth affected part such as Fig. 5, then on lamellar medicated bag 1 outside folder cartridge 6, lamellar medicated bag 1 is fixedly clamped in the tooth affected part, as Fig. 6.
The cartridge of Fig. 3 is fit to incisor and canine tooth uses, and also cartridge can be made other shapes to be fit to bicuspid and the use of grinding one's teeth in sleep, as the cartridge 8 of Fig. 7.Cartridge can adopt the elasticity such as polypropylene and non-toxic material to make.

Claims (3)

1. spacetabs type lamellar medicated bag that is used for the treatment of toothache due to pathogenic fire, comprise the medicine of having a toothache that is used for the treatment of that is encapsulated in lamellar medicated bag the inside, the composition of described medicine is by mass: by Chinese medicine extraction liquid 10-20 part that Herba Taraxaci, Herba Violae extract, vitamin B 1-5 part, thymol 1-3 part, Oleum menthae 1-5 part, Borneolum Syntheticum 1-5 part, ethanol 10-20 part;
The described Chinese medicine extraction liquid that is extracted by Herba Taraxaci, Herba Violae is to adopt Herba Taraxaci 2-6 part, and Herba Violae 2-6 part adds water 20-40 part, obtains the medicinal liquid of 10-20 part through infusion, filtration;
Described medicine is encapsulated in to have between chemosmotic surface layer and the two-layer wrapper of bottom, forms the lamellar medicated bag.
2. the spacetabs type lamellar medicated bag that is used for the treatment of toothache due to pathogenic fire according to claim 1, it is characterized in that: the fixed form of medicine in the lamellar medicated bag, adopt the liquid medicine of adsorbing material absorption to fix, after perhaps adopting pulverulent material to absorb liquid medicine, the formation granule fixes, be fixed on surface layer after perhaps adopting the liquid medicine of the adsorbing material absorption of lamellar, consist of the bottom with medicine.
3. the spacetabs type lamellar medicated bag that is used for the treatment of toothache due to pathogenic fire according to claim 1 is characterized in that: described lamellar medicated bag also matches the elastic cartridge that has that the flake double team can be fastened in the tooth affected part.
CN 201110342921 2011-10-25 2011-10-25 Sustained-release tablet-shaped cachets used for treating toothache caused by excessive internal heat Expired - Fee Related CN102362933B (en)

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Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102631406A (en) * 2012-04-12 2012-08-15 徐柔云 Mouthwash for oral ulcer
CN103006919A (en) * 2013-01-11 2013-04-03 步新源 Oral liquid for treating toothache and preparation method thereof
CA2947421C (en) * 2014-04-29 2023-05-02 Dentsply International Inc. Endodontic treatment with long term drug delivery system
CN105012390A (en) * 2015-07-31 2015-11-04 蒋魏 Medicine for removing fire and detoxifying
CN105213421A (en) * 2015-10-15 2016-01-06 桂林医学院附属医院 A kind of rinsing the mouth medicated bag for the treatment of buccal cavity fungal infection and preparation method thereof

Non-Patent Citations (4)

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Title
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牙周炎的局部药物治疗;耿晓文等;《辽宁中医药大学学报》;20070731;第9卷(第4期);31-33页 *
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