CN102357239B - Chinese medicine composition for treating chronic atrophic gastritis - Google Patents

Chinese medicine composition for treating chronic atrophic gastritis Download PDF

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Publication number
CN102357239B
CN102357239B CN2011103315635A CN201110331563A CN102357239B CN 102357239 B CN102357239 B CN 102357239B CN 2011103315635 A CN2011103315635 A CN 2011103315635A CN 201110331563 A CN201110331563 A CN 201110331563A CN 102357239 B CN102357239 B CN 102357239B
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radix
chinese medicine
medicine composition
atrophic gastritis
chronic atrophic
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CN102357239A (en
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迟荣
柳晖
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Chi Rong
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Abstract

The invention relates to a Chinese medicine composition for treating chronic atrophic gastritis. The Chinese medicine composition is made from the following Chinese medicine raw materials in weight: 10-40 g of astragalus root, 10-40 g of radix pseudostellariae, 5-30 g of root of straight ladybell, 10-40 g of ophiopogon root, 5-25 g of fried atractylodes, 2-25 g of endothelium corneum gigeriae galli, 5-25 g of Chinese angelica, 5-20 g of safflower, 4-15 g of pseudo-ginseng, 5-30 g of dandelion, 4-15 g of dried ginger and 4-15 g of radix glycyrrhizae preparata. The Chinese medicine composition provided by the invention has the functions of tonifying Qi and warming middle-Jiao, promoting blood circulation to remove blood stasis, reinforcing the stomach and promoting the production of body fluid, and promoting blood circulation to promote tissue regeneration and has a reliable curative effect on the chronic atrophic gastritis. The composition is simple and convenient to prepare and is wide in medicinal resource; and in addition, the drug natures of the ingredients are moderate and have no side effects.

Description

A kind of Chinese medicine composition for the treatment of chronic atrophic gastritis
Technical field
The present invention relates to a kind of medicinal preparation of not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of chronic atrophic gastritis.
Background technology
Chronic atrophic gastritis is a type of chronic gastritis, is the intrinsic gland atrophy of gastric mucosa (quantity reduces, and function lowers) of limitation or popularity, often with intestinal epithelial metaplasia and inflammatory reaction.With advancing age, the incidence rate of primary disease also increases thereupon, and lesion degree is also heavier, so there is the people to think that chronic atrophic gastritis is the degeneration of person in middle and old age's gastric mucosa, is a kind of " half physiology " phenomenon.Clinical manifestation is loss of appetite, feel sick, belch, epigastrium is glutted or dull pain, and severe patient can be become thin, anemia, onychorrhexis, glossitis or atrophy of tongue papillae, and minority gastric mucosal erosion person can be with upper gastrointestinal hemorrhage.Owing to the primary disease sickness rate is high, and clinically Chang Fanfu outbreak, be difficult for curing, close with being related of gastric cancer again, thereby chronic atrophic gastritis more and more is subject to people's attention.Protection gastric mucosa, anti-helicobacter pylori, enhancing gastric motility are mainly adopted in the treatment of chronic atrophic gastritis, and the symptomatic treatment such as pain relieving, its medicine has: gastric mucosal protection medicine, digestant, anti helicobacter pylori medicine, H2 receptor antagonist etc.These medicines can improve some clinical symptoms.At present, the treatment way that both at home and abroad primary disease be there is no.And the Chinese medicine primary disease has obvious advantage.
The traditional Chinese medical science is thought: weakness of the spleen and stomach, obstruction of QI are the basic pathology mechanism of chronic atrophic gastritis.Old cloudy lose, internal injury caused by excess of seven emotions, diet accumulation of phlegm, prolonged illness causes stasis of blood factors all can make spleen and stomach function impaired, lifting is unable, the mechanism of qi operation is not smooth, and presents gastral cavilty section distension, dull pain, poor appetite, the symptom such as weak.Primary disease belongs to the card of deficiency in origin and excess in superficiality, coldheat complex, and just more empty then heresy is more tied as this take weakened body resistance, and heresy is more tied then just more empty, often interacts, and is difficult to speed more.
According to theory of Chinese medical science, for the chronic atrophic gastritis pathogeny of the traditional Chinese medical science, take QI invigorating warming middle-JIAO, blood circulation promoting and blood stasis dispelling and blood granulation promoting as the rule for the treatment of, carry out dialectical composition of prescription, to reach the treating both the principal and secondary aspects of a disease purpose.
Summary of the invention
Can only play the deficiency of improvement, relief of symptoms in order to overcome prior art Chinese medicine and western medicine and naturopathy chronic atrophic gastritis, the invention provides a kind ofly prepare conveniently, the medicine source is wide, evident in efficacy, a kind of Chinese medicine composition for the treatment of chronic atrophic gastritis of having no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of chronic atrophic gastritis is characterized in that: its raw material of Chinese medicine by following weight forms: the Radix Astragali 10~40g, Radix Pseudostellariae 10~40g, Radix Adenophorae (Radix Glehniae) 5~30g, Radix Ophiopogonis 10~40g, Rhizoma Atractylodis Macrocephalae (parched) 5~25g, Endothelium Corneum Gigeriae Galli 5~25g, Radix Angelicae Sinensis 5~25g, Flos Carthami 5~20g, Radix Notoginseng 4~15g, Herba Taraxaci 5~30g, Rhizoma Zingiberis 4~15g, Radix Glycyrrhizae Preparata 4~15g.
Precedence technique scheme of the present invention is: a kind of Chinese medicine composition for the treatment of chronic atrophic gastritis is characterized in that: its raw material of Chinese medicine by following weight forms: Radix Astragali 30g, Radix Pseudostellariae 30g, Radix Adenophorae (Radix Glehniae) 20g, Radix Ophiopogonis 30g, Rhizoma Atractylodis Macrocephalae (parched) 15g, Endothelium Corneum Gigeriae Galli 15g, Radix Angelicae Sinensis 15g, Flos Carthami 10g, Radix Notoginseng 5g, Herba Taraxaci 20g, Rhizoma Zingiberis 6g, Radix Glycyrrhizae Preparata 6g.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, take QI invigorating warming middle-JIAO, blood circulation promoting and blood stasis dispelling, reinforcing stomach reg fluid and blood granulation promoting as the rule for the treatment of, and selected medicament composing prescription, treating both the principal and secondary aspects of a disease.In the Chinese medicine composition of the present invention: Radix Astragali invigorating the spleen and replenishing QI, consolidating superficial resistance granulation promoting, inducing diuresis to remove edema; Radix Pseudostellariae is mended strengthening spleen and lung, supplementing QI for promoting the production of body fluid; The cool stomach of Radix Adenophorae (Radix Glehniae) and lung heat clearing Radix Ophiopogonis, YIN nourishing and the production of body fluid promoting; Rhizoma Atractylodis Macrocephalae (parched) and middle QI invigorating, stomach strengthening spleen invigorating, dampness diuretic; Endothelium Corneum Gigeriae Galli promoting digestion and invigorating the stomach, the granulation promoting of regulating the flow of vital energy; Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation; Flos Carthami promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing; Radix Notoginseng hemostasis hemopoietic, dissipating blood stasis for subsidence of swelling, anti-inflammatory analgetic; Herba Taraxaci heat-clearing and toxic substances removing, dispersing swelling and dissipating binds; Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG are promoted blood circulation, dampness expectorant, warming the lung to resolve fluid-retention; Radix Glycyrrhizae Preparata spleen reinforcing stomach function regulating, Yiqi and vein recovery.The selected medicament composing prescription of the present invention, its drug component be through dialectical compatibility, complement each other using, and synergism, its drug effect is better than the effect of single medicine.The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, the medicine source is wide, cost is low.
The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the usefulness that is decocted in water for oral dose.Through the clinical practice checking, it is evident in efficacy reliable, and the property of medicine is gentle, toxic and side effects do not occur, and effective percentage reaches 94%, and cure rate is 46%.
The specific embodiment
The present invention will be further described below in conjunction with embodiment.
Embodiment 1
A kind of Chinese medicine composition for the treatment of chronic atrophic gastritis, its raw material of Chinese medicine by following weight forms: Radix Astragali 30g, Radix Pseudostellariae 30g, Radix Adenophorae (Radix Glehniae) 20g, Radix Ophiopogonis 30g, Rhizoma Atractylodis Macrocephalae (parched) 15g, Endothelium Corneum Gigeriae Galli 15g, Radix Angelicae Sinensis 15g, Flos Carthami 10g, Radix Notoginseng 5g, Herba Taraxaci 20g, Rhizoma Zingiberis 6g, Radix Glycyrrhizae Preparata 6g.
Embodiment 2
A kind of Chinese medicine composition for the treatment of chronic atrophic gastritis, its raw material of Chinese medicine by following weight forms: Radix Astragali 15g, Radix Pseudostellariae 40g, Radix Adenophorae (Radix Glehniae) 10g, Radix Ophiopogonis 25g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Endothelium Corneum Gigeriae Galli 10g, Radix Angelicae Sinensis 10g, Flos Carthami 5g, Radix Notoginseng 10g, Herba Taraxaci 30g, Rhizoma Zingiberis 10g, Radix Glycyrrhizae Preparata 10g.
Embodiment 3
A kind of Chinese medicine composition for the treatment of chronic atrophic gastritis, its raw material of Chinese medicine by following weight forms: Radix Astragali 40g, Radix Pseudostellariae 20g, Radix Adenophorae (Radix Glehniae) 5g, Radix Ophiopogonis 15g, Rhizoma Atractylodis Macrocephalae (parched) 5g, Endothelium Corneum Gigeriae Galli 25g, Radix Angelicae Sinensis 20g, Flos Carthami 1g, Radix Notoginseng 4g, Herba Taraxaci 10g, Rhizoma Zingiberis 4g, Radix Glycyrrhizae Preparata 15g.
Embodiment 4
A kind of Chinese medicine composition for the treatment of chronic atrophic gastritis, its raw material of Chinese medicine by following weight forms: Radix Astragali 20g, Radix Pseudostellariae 10g, Radix Adenophorae (Radix Glehniae) 30g, Radix Ophiopogonis 10g, Rhizoma Atractylodis Macrocephalae (parched) 25g, Endothelium Corneum Gigeriae Galli 5g, Radix Angelicae Sinensis 25g, Flos Carthami 12g, Radix Notoginseng 15g, Herba Taraxaci 5g, Rhizoma Zingiberis 12g, Radix Glycyrrhizae Preparata 12g.
Embodiment 5
A kind of Chinese medicine composition for the treatment of chronic atrophic gastritis, its raw material of Chinese medicine by following weight forms: Radix Astragali 10g, Radix Pseudostellariae 25g, Radix Adenophorae (Radix Glehniae) 15g, Radix Ophiopogonis 40g, Rhizoma Atractylodis Macrocephalae (parched) 20g, Endothelium Corneum Gigeriae Galli 20g, Radix Angelicae Sinensis 5g, Flos Carthami 20g, Radix Notoginseng 12g, Herba Taraxaci 15g, Rhizoma Zingiberis 15g, Radix Glycyrrhizae Preparata 4g.
Chinese medicine composition in embodiment of the invention decocting method is routinely produced medicament, and concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, add cold water and cover powder, soaked 15~20 minutes, add water again and do not have about 5 centimetres of powder, decoct.Adopt intense fire to decoct at a simmer, it is rear with slow fire boiling 20~30 minutes to boil; Second decocts, the water rear decoction 15~20 minutes of boiling.Decoct extracting juice twice, merge.
A kind of Chinese medicine composition for the treatment of chronic atrophic gastritis, clinical efficacy is summed up:
One, general data: this Chinese medicine composition is applied to clinical observation case 50 examples, male 28 examples wherein, women 22 examples, 25~70 years old its age.
Two, usage and dosage: during clinical practice, the component in the compositions is taken the circumstances into consideration increase and decrease according to patient's body weight and age.This Chinese medicine composition potion on the one, the about 300ml of twice extracting juice of decocting divides early, takes for late twice.
Three, efficacy assessment standard:
(1), recovery from illness: clinical symptoms and sign disappear, and appetite is normal;
(2), produce effects: face flavor symptom and sign and substantially disappear, appetite is improved;
(3), effective: clinical symptoms and sign obviously alleviate, but still leave over a part of symptom;
(4), invalid: clinical symptoms and sign slightly are improved or without improvement.
Four, therapeutic effect: in this clinical observation case, took medicine 23 examples of fully recovering, produce effects 18 examples, effective 6 examples, invalid 3 examples 1-6 month.Toxic and side effects does not occur during the treatment.
Five, model case:
Case 1
Grandson, man, 53 years old.When medical: the upper abdomen distending pain, anti-sour ﹑ gas ﹑ beats belch ﹑, and to receive poor ﹑ weak 5 years, increased the weight of in nearly 2 years.Take the decoction 3 months of Chinese medicine composition of the present invention preparation, Shang abdomen Teng Tong ﹑ flatulence disappears, and appetite increases, and health is strong, and the malaise symptoms such as anti-Suan ﹑ Ai Qi ﹑ xerostomia disappear.Continue to strengthen the treatment take 1 month after, the recovery from illness; Follow up a case by regular visits to and have no recurrence half a year.
Case 2
Poplar, woman, 42 years old.Main suit when medical: epigastrium is pain repeatedly.Abdominal distention, belch, heartburn, inappetence more than 8 years.Take the decoction 1 month of Chinese medicine composition of the present invention preparation, pain, abdominal distention, be clearly better, appetite increases, and continues to take treatment 3 months, clinical symptom disappearance, and appetite spirit is normal.
Case 3
The Wang, man, 38 years old.Main suit when medical: because diet is irregular, drink, have a stomach-ache, have the hiccups, after the meal glutted, stomachache, diarrhoea and constipation replace, inappetence is with bitter taste.Take the decoction 1 month of Chinese medicine composition of the present invention preparation, have a stomach-ache, have the hiccups, the clinical symptom disappearance such as glutted after the meal; Continue to strengthen and take treatment 1 month, recovery from illness.

Claims (2)

1. Chinese medicine composition for the treatment of chronic atrophic gastritis, it is characterized in that, made by the raw material of Chinese medicine of following weight: the Radix Astragali 10~40g, Radix Pseudostellariae 10~40g, Radix Adenophorae (Radix Glehniae) 5~30g, Radix Ophiopogonis 10~40g, Rhizoma Atractylodis Macrocephalae (parched) 5~25g, Endothelium Corneum Gigeriae Galli 5~25g, Radix Angelicae Sinensis 5~25g, Flos Carthami 5~20g, Radix Notoginseng 4~15g, Herba Taraxaci 5~30g, Rhizoma Zingiberis 4~15g, Radix Glycyrrhizae Preparata 4~15g.
2. a kind of Chinese medicine composition for the treatment of chronic atrophic gastritis according to claim 1, it is characterized in that, made by the raw material of Chinese medicine of following weight: Radix Astragali 30g, Radix Pseudostellariae 30g, Radix Adenophorae (Radix Glehniae) 20g, Radix Ophiopogonis 30g, Rhizoma Atractylodis Macrocephalae (parched) 15g, Endothelium Corneum Gigeriae Galli 15g, Radix Angelicae Sinensis 15g, Flos Carthami 10g, Radix Notoginseng 5g, Herba Taraxaci 20g, Rhizoma Zingiberis 6g, Radix Glycyrrhizae Preparata 6g.
CN2011103315635A 2011-10-27 2011-10-27 Chinese medicine composition for treating chronic atrophic gastritis Expired - Fee Related CN102357239B (en)

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Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102886035A (en) * 2012-09-19 2013-01-23 陈正梅 Medicament for treating chronic gastroenteropathy
CN103446532A (en) * 2013-08-14 2013-12-18 马靖已 Traditional Chinese medicine decoction for treating gastritis
CN103735993A (en) * 2014-01-15 2014-04-23 简厚奎 Drug for treating stomach diseases
CN103877480B (en) * 2014-03-04 2017-06-23 辽宁省中医药研究院 A kind of medicine for treating chronic gastritis and gastric motility disorder and preparation method thereof
CN107158345A (en) * 2017-06-07 2017-09-15 徐俊鸽 A kind of Chinese medicine for treating chronic gastritis
CN109303848A (en) * 2018-12-06 2019-02-05 陕西中医药大学 It is a kind of for preventing and treating the pharmaceutical composition of precancerous lesions of chronic atrophic gastritis

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1045351A (en) * 1989-03-10 1990-09-19 兰州医学院第一附属医院 A kind of manufacture method for the treatment of the chronic atrophic gastritis medicine

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1045351A (en) * 1989-03-10 1990-09-19 兰州医学院第一附属医院 A kind of manufacture method for the treatment of the chronic atrophic gastritis medicine

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