CN102333887B - 用于检测gi癌转移的方法 - Google Patents

用于检测gi癌转移的方法 Download PDF

Info

Publication number
CN102333887B
CN102333887B CN201080009215.XA CN201080009215A CN102333887B CN 102333887 B CN102333887 B CN 102333887B CN 201080009215 A CN201080009215 A CN 201080009215A CN 102333887 B CN102333887 B CN 102333887B
Authority
CN
China
Prior art keywords
gcc
gusb
cancer
sample
purposes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201080009215.XA
Other languages
English (en)
Chinese (zh)
Other versions
CN102333887A (zh
Inventor
简-弗朗索瓦·海伊斯
纪尧姆·博德里
吉纳维芙·加龙
迈克尔·霍德
蒂莫西·J·霍尔泽
马丁·比利
尼古拉斯·贝特朗
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diagnocure Inc
Original Assignee
Diagnocure Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diagnocure Inc filed Critical Diagnocure Inc
Publication of CN102333887A publication Critical patent/CN102333887A/zh
Application granted granted Critical
Publication of CN102333887B publication Critical patent/CN102333887B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57535Immunoassay; Biospecific binding assay; Materials therefor for cancer of the large intestine, e.g. colon, rectum or anus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/527Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201080009215.XA 2009-02-25 2010-02-24 用于检测gi癌转移的方法 Expired - Fee Related CN102333887B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US15517209P 2009-02-25 2009-02-25
US61/155,172 2009-02-25
US24619709P 2009-09-28 2009-09-28
US61/246,197 2009-09-28
PCT/CA2010/000277 WO2010096929A1 (en) 2009-02-25 2010-02-24 Method for detecting metastasis of gi cancer

Publications (2)

Publication Number Publication Date
CN102333887A CN102333887A (zh) 2012-01-25
CN102333887B true CN102333887B (zh) 2014-04-02

Family

ID=42664977

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201080009215.XA Expired - Fee Related CN102333887B (zh) 2009-02-25 2010-02-24 用于检测gi癌转移的方法

Country Status (7)

Country Link
US (1) US20110306055A1 (https=)
EP (2) EP2677036A3 (https=)
JP (1) JP2012518389A (https=)
CN (1) CN102333887B (https=)
AU (1) AU2010217160C1 (https=)
CA (1) CA2752668A1 (https=)
WO (1) WO2010096929A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY173390A (en) 2009-10-23 2020-01-22 Takeda Pharmaceuticals Co Anti-gcc antibody molecules and related compositions and methods
US9416410B2 (en) * 2012-02-14 2016-08-16 Genetics Development Corporation Cutoff point delta Ct. method for HER2 PCR testing in breast cancer
ME03560B (me) 2012-04-27 2020-07-20 Millennium Pharm Inc MOLEKULI ANTI-GCC ANTITELA l NJIHOVA UPOTREBA U ISPITIVANJU OSETLJIVOSTI NA GCC-CILJANU TERAPIJU
WO2016028141A1 (en) * 2014-08-18 2016-02-25 Universiti Kebangsaan Malaysia Method for determining prognosis of colorectal cancer
EP4706525A3 (en) 2014-09-25 2026-04-22 BT Bidco, Inc. Electromechanical pill device with localization capabilities
EP3500177A1 (en) * 2016-08-18 2019-06-26 Mitchell Lawrence Jones Systems for obtaining samples using ingestible devices
KR20230042759A (ko) 2016-09-09 2023-03-29 비오라 쎄라퓨틱스, 인크. 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스
US10610104B2 (en) 2016-12-07 2020-04-07 Progenity, Inc. Gastrointestinal tract detection methods, devices and systems
US11761032B2 (en) * 2017-03-11 2023-09-19 Yan Wang Methods and devices for performing real time digital PCR
EP3900613B1 (en) 2017-03-31 2023-12-27 Biora Therapeutics, Inc. Localization methods for an ingestible device
US20220249814A1 (en) 2018-11-19 2022-08-11 Progenity, Inc. Methods and devices for treating a disease with biotherapeutics
CN110819715A (zh) * 2019-11-26 2020-02-21 华夏帮服科技有限公司 用于结直肠癌检测的免疫基因标志物及试剂盒
CN118460719A (zh) * 2020-03-02 2024-08-09 腾辰生物科技(上海)有限公司 一种分子标志物及试剂盒在辅助诊断食管癌中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008045133A2 (en) * 2006-03-03 2008-04-17 Veridex, Llc Molecular assay to predict recurrence of dukes' b colon cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5601990A (en) 1994-09-13 1997-02-11 Thomas Jefferson University Methods of diagnosing colorectal tumors and metastasis thereof
EP0734264B1 (en) 1993-10-26 2004-02-18 Thomas Jefferson University Compositions that specifically bind to colorectal cancer cells and methods of using the same
WO1997042506A1 (en) 1996-05-03 1997-11-13 Thomas Jefferson University Methods of and kits and compositions for diagnosing colorectal tumors and metastasis thereof
US7135333B1 (en) 1997-08-07 2006-11-14 Thomas Jefferson University Compositions that specifically bind to colorectal cancer cells and methods of using the same
US6120995A (en) 1997-08-07 2000-09-19 Thomas Jefferson University Compositions that specifically bind to colorectal cancer cells and methods of using the same
AU2001249548A1 (en) 2000-03-27 2001-10-08 Thomas Jefferson University Compositions and methods for identifying and targeting cancer cells
US7138226B2 (en) 2002-05-10 2006-11-21 The University Of Miami Preservation of RNA and morphology in cells and tissues
US20040018494A1 (en) * 2002-07-25 2004-01-29 Shurtliff Roxanne N Isothermal transcription based amplification assay for detection and quantification of guanylyl cyclase C
DE102004024617A1 (de) * 2004-05-18 2005-12-29 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008045133A2 (en) * 2006-03-03 2008-04-17 Veridex, Llc Molecular assay to predict recurrence of dukes' b colon cancer

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Real-time reverse transcription PCR and the detection of occult disease in colorectal cancer;Stephen A. Bustin等;《Molecular Aspects of Medicine》;20060630;第27卷;正文第2.4节第1-2段、第2.5.3节第1段 *

Also Published As

Publication number Publication date
EP2401394B1 (en) 2013-11-27
JP2012518389A (ja) 2012-08-16
CN102333887A (zh) 2012-01-25
EP2677036A2 (en) 2013-12-25
EP2677036A3 (en) 2014-01-22
CA2752668A1 (en) 2010-09-02
AU2010217160C1 (en) 2015-07-02
HK1165836A1 (en) 2012-10-12
WO2010096929A1 (en) 2010-09-02
EP2401394A1 (en) 2012-01-04
US20110306055A1 (en) 2011-12-15
AU2010217160B2 (en) 2014-11-20
EP2401394A4 (en) 2012-07-11
AU2010217160A1 (en) 2011-09-22

Similar Documents

Publication Publication Date Title
CN102333887B (zh) 用于检测gi癌转移的方法
US10494677B2 (en) Predicting cancer outcome
ES2741745T3 (es) Método para usar la expresión génica para determinar el pronóstico de cáncer de próstata
ES3027507T3 (en) Method to use gene expression to determine likelihood of clinical outcome of renal cancer
Rahbari et al. Identification of differentially expressed microRNA in parathyroid tumors
CN105102636B (zh) 用于检测和测定前列腺癌预后的组合物和方法
JP6782700B2 (ja) 膵・消化管神経内分泌新生物の診断のための組成物、方法およびキット
WO2015073949A1 (en) Method of subtyping high-grade bladder cancer and uses thereof
US20130323740A1 (en) Direct blood assay for detection of circulating microrna in cancer patients
US20130303400A1 (en) Multimarker panel
KR102036222B1 (ko) 당뇨병성 신증에 의한 만성신장질환 환자의 예후 예측용 마커
WO2011117586A1 (en) Prognosis of oesophageal and gastro-oesophageal junctional cancer
CN111763736A (zh) 用于诊断甲状腺乳头状癌淋巴结转移的液体活检试剂盒
EP4317458A1 (en) Follicular thyroid cancer-specific marker
KR102036221B1 (ko) 만성신장질환의 예후 예측을 위한 후성 유전학적 진단 키트 개발
KR102036220B1 (ko) 만성신장질환 특이적 후성학적 메틸화 마커 검출용 조성물 및 검출방법
KR102036219B1 (ko) 유전자 프로모터의 CpG 메틸화 변화를 이용한 만성신장질환의 악화 예측용 조성물 및 이의 이용
KR20260025789A (ko) 비전이성 여성 유방암의 예후 예측 방법
CN116121369A (zh) 肾癌相关生物标志物及其应用和检测方法
HK1165836B (en) Method for detecting metastasis of gi cancer
HK1213297B (zh) 用於檢測和測定前列腺癌預後的組合物和方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20140402

Termination date: 20170224