CN102309668B - Medicament for treating anemopyretic toothache and preparation method thereof - Google Patents

Medicament for treating anemopyretic toothache and preparation method thereof Download PDF

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CN102309668B
CN102309668B CN2010102205703A CN201010220570A CN102309668B CN 102309668 B CN102309668 B CN 102309668B CN 2010102205703 A CN2010102205703 A CN 2010102205703A CN 201010220570 A CN201010220570 A CN 201010220570A CN 102309668 B CN102309668 B CN 102309668B
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仲宝根
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Abstract

The invention relates to a medicament for treating anemopyretic toothache, which is prepared from the following raw materials by weight: 13 to 17g of mint, 16 to 20g of weeping forsythia, 10 to 14g of great burdock achene, 10 to 14g of honeysuckle, 10 to 14g of gypsum, 6 to 10g of buerger pipewort flower, 3 to 7g of scaphium scaphigerum, 7 to 11g of raw rehmannia, 6 to 10g of fineleaf schizonepeta herb, and 5 to 9g of common anemarrhena. The medicament is prepared by the following steps of: a) weighing the following Chinese medicaments serving as raw materials by weight: mint, weeping forsythia, great burdock achene, honeysuckle, gypsum, buerger pipewort flower, scaphium scaphigerum, raw rehmannia, fineleaf schizonepeta herb and common anemarrhena; b) preparing high alcohol into a 70 percent alcohol solution; c) immersing the quantitative medicaments in the formula into the alcohol solution; and d) sealing and storing for one month, adding musk and borneol, dissolving to obtain the medicament. The medicament can radically treat the anemopyretic toothache, ensures that the anemopyretic toothache hardly relapses, and is safe and reliable in clinical application without any toxic or side effect.

Description

A kind of medicine of treating toothache due to pathogenic wind-heat and preparation method thereof
Affiliated field
The present invention relates to a kind of Chinese medicine medical material, specifically medicine of a treatment toothache due to pathogenic wind-heat and preparation method thereof.
Background technology
Toothache is one of common symptom of odontopathy, and tooth and periodontal disease all can be had a toothache.The different causes of disease according to toothache can be divided into types such as toothache due to pathogenic wind-cold, toothache due to pathogenic wind-heat, toothache due to stomach-fire, toothache caused by fire of deficiency type, toothache due to dental caries, nervous toothache.Thumping majority hospital adopts doctor trained in Western medicine Zhi Ya at present, and traditional Chinese medical science dentistry is seldom arranged.Doctor trained in Western medicine is controlled toothache has three kinds of methods substantially: the one, and antiinflammatory, the 2nd, dental nerve is controlled extremely, cause the pain tooth to wither and come off, the 3rd, with pulling out after the antiinflammatory of pain tooth.These three kinds of methods all are the passive therapies of curing the symptoms, not the disease.
Defectives such as the Chinese medicine of existing treatment toothache also has a variety of, takes effect slowly but all exist to some extent, and curative effect is remarkable inadequately.
Summary of the invention
To above defective, pro-philtrum of the present invention is cured on the theoretical basis of tooth, repetition test; Concentrate on studies for many years; Haveing breakthrough aspect the utilization Chinese medicine radical cure toothache, its Therapeutic Method is relaxing muscles and tendons to promote blood circulation, dispel the wind, dispel the heat, dehumidifying, pain relieving, and it is healthy that the pain tooth is brought back to life; Be characterized in instant effect, can effect a radical cure, be difficult for recurrence, simple, curative effect is high, and cure rate is high.
In order to reach above purpose, the invention provides a kind of medicine of treating toothache due to pathogenic wind-heat and preparation method thereof, its toothache due to pathogenic wind-heat curative effect is 100%, cure rate is 92.9%.
The objective of the invention is to realize through following technical scheme: a kind of medicine of treating toothache due to pathogenic wind-heat, it is the medicine of being processed by following materials of weight proportions: Herba Menthae 13-17 gram, Fructus Forsythiae 16-20 gram, Fructus Arctii 10-14 gram, Flos Lonicerae 10-14 gram, Gypsum Fibrosum 10-14 gram, Flos Eriocauli 6-10 gram, Semen Sterculiae Lychnophorae 3-7 gram, Radix Rehmanniae 7-11 gram, Herba Schizonepetae 6-10 gram, Rhizoma Anemarrhenae 5-9 gram.
The suitable weight proportion of the present invention is: Herba Menthae 15 grams, Fructus Forsythiae 18 grams, Fructus Arctii 12 grams, Flos Lonicerae 12 grams, Gypsum Fibrosum 12 grams, Flos Eriocauli 8 grams, Semen Sterculiae Lychnophorae 5 grams, Radix Rehmanniae 9 grams, Herba Schizonepetae 8 grams, the Rhizoma Anemarrhenae 7 grams.
The present invention has following steps:
A), make raw material by weight taking by weighing following traditional Chinese medicines earlier: Herba Menthae, Fructus Forsythiae, Fructus Arctii, Flos Lonicerae, Gypsum Fibrosum, Flos Eriocauli, Semen Sterculiae Lychnophorae, Radix Rehmanniae, Herba Schizonepetae, the Rhizoma Anemarrhenae.
B), then height ethanol is made into 70% ethanol liquid;
C), the pharmaceutical in will filling a prescription again is soaked in the ethanol liquid;
D), sealing stores after one month, adds a little Moschus and Borneolum Syntheticum, promptly get after dissolving.
After adopting above technical scheme, the present invention has following beneficial effect: first is superior to the treatment of Western medicine to toothache due to pathogenic wind-heat.Because Western medicine is through the anti-inflammatory treatment toothache, though can temporarily cure, because of fundamentally not dispeling wind, heat, damp, so be prone to recurrence, this is the method for curing the symptoms, not the disease.Second Chinese medicine preparation that be superior to occurring in the market.Because existing Chinese medicine preparation, like the spirit of tooth disease etc., all be the comprehensive preparation of controlling toothache, thus also can only mainly control toothache as Western medicine with antiinflammatory, can not the symptomatic treatment toothache, also be the method for curing the symptoms, not the disease.In a word, toothache due to pathogenic wind-heat liquid is quick, the efficient medicine that a kind of treating both the principal and secondary aspects of a disease of suiting the medicine to the illness is difficult for recurrence.If can large quantities of this medicines that put into production, with regard to the treatment of replaceable Western medicine and existing Chinese medicine preparation to toothache due to pathogenic wind-heat.
The present invention has following characteristic for the treatment toothache due to pathogenic wind-heat:
One, pathological analysis
Wind, heat, damp all can make meridians be obstructed, and cause odontopathy such as gingivitis, periodontitis, pericoronitis, thereby have a toothache.Therefore must dispel wind, heat, damp, get through meridians, can effect a radical cure toothache due to pathogenic wind-heat.
Therapy for clearing away heat in the eight therapeutic methods, i.e. " method of clearing away heat-fire "." element ask the most pure virginity will discuss greatly " said: " treating heat syndrome with cold-natured drugs ", " treating heat syndrome with drugs of cold nature ".Also need use simultaneously resolving therapy to dispel wind, wet heresy.This is the pathologic basis of treatment toothache due to pathogenic wind-heat.
" element ask lift pain opinion " pointed out for a long time: the basic pathology of " general rule is logical, and general rule is not bitterly " changes, so the treatment toothache must the dual-purpose blood circulation promoting and blood stasis dispelling, the medicine of dredging the meridian quickens the unobstructed of meridians, the raising curative effect.
Two, pharmacology analysis
1, syndrome: red swelling of gingiva, affected part get cold then alleviation of pain, are heated then to increase bitterly, or heating, aversion to cold, thirsty are arranged, red tongue, tongue white spirit, floating and rapid pulse.
2, method of treatment: suitable wind and heat dispersing, the evil sterilization of loosing, collateral dredging, reducing swelling and alleviating pain.
3, medicine: Herba Menthae, Fructus Forsythiae, Fructus Arctii, Flos Lonicerae, Gypsum Fibrosum, Flos Eriocauli, Semen Sterculiae Lychnophorae, Radix Rehmanniae, Herba Schizonepetae, the Rhizoma Anemarrhenae.
4, medicine is resolved:
(1) Herba Menthae.Acrid in the mouth, cool in nature.Return lung, Liver Channel.Effect: relieving the exterior syndrome by diaphoresis, dispelling wind and heat pathogens, the clear sharp head, promoting QI circulation for relieving depression.
" book on Chinese herbal medicine is looked for the truth ": " Herba Menthae, abnormal smells from the patient is refrigerant ... cool can heat clearing away, in throat, ability to speak, eye, ear, addiction examine, skin ulcer scabies, fever (of children) accompanied by fear, hectic fever due to YIN-deficiency, epistaxis be then wonderful "." medicineization justice ": " Herba Menthae, acrid in the mouth can loose, and is cool in nature and clear, and the meeting of tonneau six sun is first, dispels the ailment said due to cold or exposure of all heat.It is sharp and light clear to get its property, and the benefaction women's head-ornaments with controlling aphonia, are treated ability to speak, clearing throat ".
Judgement: as the toothache due to pathogenic wind-heat principal agent.
(2) Fructus Forsythiae.Bitter in the mouth, cold nature.GUIXIN, liver, gallbladder, small intestine meridian.Effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.
Fructus Forsythiae and Flos Lonicerae all have good antipyretic and antidote functions, can diathermanously reach table, again can the removing summer-heat interior-heat, dispersing swelling and dissipating binds, so the frequent mutual reinforcement between of two medicines is for using.
" Records of Tradition Chinese and Western Medicine in Combination ": " for controlling the wind heat key medicine ... the kind again disease of controlling the head, all headaches, ophthalmalgia, painful, the nasal sinusitis of tooth ... all lead it ".
Judgement: as the toothache due to pathogenic wind-heat principal agent.
(3) Fructus Arctii.Acrid in the mouth, hardship, cold in nature.Attach to the lung and stomach meridians.Effect: dispelling wind and heat pathogens, detoxifcation rash, relieving sore throat and diminishing swelling.
" property of medicine opinion ": " remove all wind, Li Yaojiao, all tuberosity muscles and bones dysphoria with smothery sensation poison loose again "." Bencao Jingshu ": " removing the key medicine of thermal detoxification for the wind that looses ... logical twelve channels and collaterals ".
Judgement: as the toothache due to pathogenic wind-heat accessory drugs.
(4) Flos Lonicerae.Sweet in the mouth, cold in nature.Return lung, stomach, large intestine channel.Effect: heat-clearing and toxic substances removing.
The power of Flos Lonicerae heat-clearing and toxic substances removing is quite strong, because these article sweet in the mouth is cold in nature, fragrant odour so both can pass through relieving the exterior syndrome clearly, can be separated nutrient blood again and divide pyretic toxicity, particularly controls the key medicine of positive skin infection.These article heat clearing away and not feeling frustrated, removing toxic substances and non-impairment of YIN are for treating the good merchantable brand of warm fire-toxin.
Compendium of Material Medica: control " all rheumatism gas, and all toxic swellings ".
Judgement: as the toothache due to pathogenic wind-heat accessory drugs.
(5) Gypsum Fibrosum.Acrid in the mouth, sweet, property Great Cold.Attach to the lung and stomach meridians.Effect: clearing away heat-fire, relieving restlessness is quenched the thirst, and holds back the skin ulcer hemostasis.
These article abnormal smells from the patient is hot cold, and its clearing away heat-fire effect is rather remarkable, is longer than especially and rushes down the edema caused by disorder of QI excess-heat clearly, is the main medicine of the warm pathogenic factor of treatment in the edema caused by disorder of QI stage.
" Japan hanako materia medica ": " wiping tooth benefit tooth ".
Judgement: as the toothache due to pathogenic wind-heat adjuvant.
(6) Flos Eriocauli.Sweet in the mouth, property is flat.Return liver, stomach warp.Effect: dispelling wind and heat pathogens, improving acuity of vision and removing nebula.
" Kaibao Bencao ": " sore throat, tooth wind pain, all skin ulcer scabies ".
Judgement: as the toothache due to pathogenic wind-heat accessory drugs.
(7) Semen Sterculiae Lychnophorae.Sweet in the mouth, light, cool in nature.Return lung, large intestine channel.Effect: open the lung heat clearing away, loosening bowel to relieve constipation.
Supplementary Amplifications of the Compendium of Materia Medica: " control acute toothache, malnutrition due to parasitic infestation, following food, the hemorrhoid fistulae, dry cough without phlegm, the hectic fever due to YIN-deficiency interior-heat, the three warmers fire syndrome, all skin ulcers are all imitated ".
Judgement: as the toothache due to pathogenic wind-heat accessory drugs.
(8) Radix Rehmanniae.Sweet in the mouth, hardship, cold in nature.GUIXIN, liver, kidney channel.Effect: clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting.
Judgement: as the toothache due to pathogenic wind-heat adjuvant drug.
(9) Herba Schizonepetae.Acrid in the mouth, slightly warm in nature.Go into lung, Liver Channel.Effect: inducing diaphoresis to dispel wind and blood hemostasis.
Herba Schizonepetae has the merit of inducing sweat, dispel the wind, stopping blooding, the heresy of kind dispersing wind and cold wind and cold.
Judgement: as the toothache due to pathogenic wind-heat adjuvant drug.
(10) Rhizoma Anemarrhenae.Bitter in the mouth, sweet, cold in nature.Return lung, stomach, kidney channel.Effect: clearing away heat-fire is nourshing Yin and drynsessmoistening prescription.
These article are again nourshing Yin and drynsessmoistening prescription common drugs for clearing heat in QI system divides the staple of excess-heat.
Judgement: as the toothache due to pathogenic wind-heat adjuvant drug.
5, prescription: according to pathology, pharmacology characteristic, toothache due to pathogenic wind-heat should adopt Herba Menthae Fructus Forsythiae side: Herba Menthae 15 grams, Fructus Forsythiae 18 grams, Fructus Arctii 12 grams, Flos Lonicerae 12 grams, Gypsum Fibrosum 12 grams, Flos Eriocauli 8 grams, Semen Sterculiae Lychnophorae 5 grams, Radix Rehmanniae 9 grams, Herba Schizonepetae 8 grams, the Rhizoma Anemarrhenae 7 grams.
6, the side separates: Herba Menthae, Fructus Forsythiae wind and heat dispersing in the side, and reducing swelling and alleviating pain is principal agent altogether; Fructus Arctii wind and heat dispersing detoxifcation, Flos Lonicerae heat-clearing and toxic substances removing, the Flos Eriocauli pyretic arthralgia that dispels the wind, Semen Sterculiae Lychnophorae heat clearing away cool in nature, the Gypsum Fibrosum clearing away heat-fire helps principal agent to strengthen curative effect altogether, all is accessory drugs; The Radix Rehmanniae clearing away heat and cooling blood, the hemostasis of Herba Schizonepetae and blood, and tepor have the corrigent effect, Rhizoma Anemarrhenae clearing heat and moistening dryness, and Gypsum Fibrosum dampness, a profit one is dry, and the corrigent effect is also arranged, and these four medicines assistants are adjuvant drug with the principal agent therapeutical effect that finishes altogether.The long memorial wind heat clearing away altogether of full side, the evil sterilization of loosing, the effect of reducing swelling and alleviating pain.
7, manufacture method: earlier will height ethanol be made into 260 milliliters of 70% ethanol liquid, the pharmaceutical in will fill a prescription again is soaked in the ethanol liquid, and the sealing storage added 10 milligrams of Moschus and 30 milligrams of Borneolum Syntheticums after one month, can use after dissolving.
The name of this medicinal liquid is called the toothache due to pathogenic wind-heat spirit.
Below in conjunction with embodiment the present invention is described further.
The specific embodiment
A kind of medicine of treating toothache due to pathogenic wind-heat, it is the medicine of being processed by following materials of weight proportions: Herba Menthae 13-17 gram, Fructus Forsythiae 16-20 gram, Fructus Arctii 10-14 gram, Flos Lonicerae 10-14 gram, Gypsum Fibrosum 10-14 gram, Flos Eriocauli 6-10 gram, Semen Sterculiae Lychnophorae 3-7 gram, Radix Rehmanniae 7-11 gram, Herba Schizonepetae 6-10 gram, Rhizoma Anemarrhenae 5-9 gram.
The suitable weight proportion of the present invention is: Herba Menthae 15 grams, Fructus Forsythiae 18 grams, Fructus Arctii 12 grams, Flos Lonicerae 12 grams, Gypsum Fibrosum 12 grams, Flos Eriocauli 8 grams, Semen Sterculiae Lychnophorae 5 grams, Radix Rehmanniae 9 grams, Herba Schizonepetae 8 grams, the Rhizoma Anemarrhenae 7 grams.
The present invention has following steps:
A), make raw material by weight taking by weighing following traditional Chinese medicines earlier: Herba Menthae, Fructus Forsythiae, Fructus Arctii, Flos Lonicerae, Gypsum Fibrosum, Flos Eriocauli, Semen Sterculiae Lychnophorae, Radix Rehmanniae, Herba Schizonepetae, the Rhizoma Anemarrhenae.
B), then height ethanol is made into 70% ethanol liquid;
C), the pharmaceutical in will filling a prescription again is soaked in the ethanol liquid;
D), sealing stores after one month, adds 10 milligrams of Moschus and 30 milligrams of Borneolum Syntheticums, promptly get after dissolving.
The concrete method for using of the present invention: medicinal liquid is sucked in the bottle of eye drop size, point is at the pain tooth root, and the wind heat of can loosing relieves the pain bitterly.
8, a kind of medicine of treating toothache due to pathogenic wind-heat of the present invention, clinical trial:
(1) contrast experiment of the composition of compound medicine and weight ratio group:
1. Herba Menthae 13 grams, Fructus Forsythiae 16 restrain, Fructus Arctii 10 grams, and Flos Lonicerae 10 grams, Gypsum Fibrosum 10 grams, Flos Eriocauli 6 grams, Semen Sterculiae Lychnophorae 3 restrains, Radix Rehmanniae 7 grams, Herba Schizonepetae 6 grams, the Rhizoma Anemarrhenae 5 grams.
2. Herba Menthae 15 grams, Fructus Forsythiae 18 restrain, Fructus Arctii 12 grams, and Flos Lonicerae 12 grams, Gypsum Fibrosum 12 grams, Flos Eriocauli 8 grams, Semen Sterculiae Lychnophorae 5 restrains, Radix Rehmanniae 9 grams, Herba Schizonepetae 8 grams, the Rhizoma Anemarrhenae 7 grams.
3. Herba Menthae 17 grams, Fructus Forsythiae 20 restrain, Fructus Arctii 14 grams, and Flos Lonicerae 14 grams, Gypsum Fibrosum 14 grams, Flos Eriocauli 10 grams, Semen Sterculiae Lychnophorae 7 restrains, Radix Rehmanniae 11 grams, Herba Schizonepetae 10 grams, the Rhizoma Anemarrhenae 9 grams.
Toothache due to pathogenic wind-heat the is group (best group) clinical trial instance 2.
Figure 660409DEST_PATH_GSB00000331247900011
Figure 98344DEST_PATH_GSB00000331247900021
Figure 518961DEST_PATH_GSB00000331247900031
Figure 991530DEST_PATH_GSB00000331247900041
Figure 104980DEST_PATH_GSB00000331247900051
(2) clinical test results:
The 1. group be the poor efficiency weight composition group of compound medicine;
The 2.) group is that the optimum weight composition group of compound medicine, its curative effect are 100%, cure rate is 92.9%;
The 3. group be the preferred weight composition group of compound medicine.
Visible from clinical observation result, a kind of medicine of treating toothache due to pathogenic wind-heat of the present invention and preparation method thereof can effect a radical cure for toothache due to pathogenic wind-heat, is difficult for recurrence, and clinical practice is safe and reliable, and is without any side effects.

Claims (2)

1. medicine of treating toothache due to pathogenic wind-heat; It is characterized in that it is the medicine of being processed by following materials of weight proportions: Herba Menthae 13-17 gram, Fructus Forsythiae 16-20 gram, Fructus Arctii 10-14 gram, Flos Lonicerae 10-14 gram, Gypsum Fibrosum 10-14 gram, Flos Eriocauli 6-10 gram, Semen Sterculiae Lychnophorae 3-7 gram, Radix Rehmanniae 7-11 gram, Herba Schizonepetae 6-10 gram, Rhizoma Anemarrhenae 5-9 gram, this process for preparing medicine has following steps:
A), make raw material by weight taking by weighing following traditional Chinese medicines earlier: Herba Menthae, Fructus Forsythiae, Fructus Arctii, Flos Lonicerae, Gypsum Fibrosum, Flos Eriocauli, Semen Sterculiae Lychnophorae, Radix Rehmanniae, Herba Schizonepetae, the Rhizoma Anemarrhenae;
B), then height ethanol is made into 70% ethanol liquid;
C), the pharmaceutical in will filling a prescription again is soaked in the ethanol liquid;
D), sealing stores after one month, adds 10 milligrams of Moschus and 30 milligrams of Borneolum Syntheticums, promptly get after dissolving.
2. a kind of medicine of treating toothache due to pathogenic wind-heat according to claim 1 is characterized in that suitable weight proportion is: Herba Menthae 15 grams, Fructus Forsythiae 18 grams, Fructus Arctii 12 grams, Flos Lonicerae 12 grams, Gypsum Fibrosum 12 grams, Flos Eriocauli 8 grams, Semen Sterculiae Lychnophorae 5 grams, Radix Rehmanniae 9 grams, Herba Schizonepetae 8 grams, the Rhizoma Anemarrhenae 7 grams.
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CN105434703A (en) * 2015-12-10 2016-03-30 韦焜 Traditional Chinese medicine composition for treating toothache caused by wind-heat
CN105433229A (en) * 2015-12-10 2016-03-30 韦焜 Instant powder for treating toothache caused by wind-heat and preparation method thereof
CN110680884A (en) * 2018-07-06 2020-01-14 高全良 Toothache relieving medicinal powder and preparation method thereof

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