CN102284003B - Traditional Chinese medicine composition for treating semen non-liquefaction - Google Patents
Traditional Chinese medicine composition for treating semen non-liquefaction Download PDFInfo
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- CN102284003B CN102284003B CN2011102369568A CN201110236956A CN102284003B CN 102284003 B CN102284003 B CN 102284003B CN 2011102369568 A CN2011102369568 A CN 2011102369568A CN 201110236956 A CN201110236956 A CN 201110236956A CN 102284003 B CN102284003 B CN 102284003B
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Abstract
The invention belongs to the technical field of andrology in traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating semen non-liquefaction. The traditional Chinese medicine composition for treating semen non-liquefaction is prepared from the following active pharmaceutical ingredients in parts by weight: 25-35 parts of radix salviae miltiorrhizae, 20-30 parts of honeysuckle flower, 15-25 parts of epimedium, 5-15 parts of angelica, 10-20 parts of radix rehmanniae preparata, 10-20 parts of radix paeoniae alba, 5-15 parts of red paeonia, 5-15 parts of rhizoma anemarrhenae, 5-15 parts of phellodendron bark, 10-20 parts of radix trichosanthis, 10-20 parts of white gourd seed, 5-15 parts of wolfberry fruit, 6-10 parts of schisandra fruit, 10-20 parts of dodder, 5-15 parts of tuckahoe, 10-20 parts of fleece-flower root, 10-15 parts of rhizoma alismatis, 10-15 parts of Fructus Forsythiae, 10-20 parts of rhizoma polygonati, 5-15 parts of moutan bark, 10-20 parts of tortoise plastron, 5-15 parts of rhizoma cyperi and 4-8 parts of licorice root. The traditional Chinese medicine composition for treating semen non-liquefaction has the effects of nourishing yin to reduce pathogenic fire, resolving phlegm, eliminating stasis and clearing away heat and toxic material, and has obvious curative effect; and the total effective rate is 96%.
Description
Technical field
The invention belongs to Chinese medicine andrology technical field, be specifically related to a kind of Chinese medicine composition of treating seminal fluid not liquefaction.
Background technology
Under the normal condition; Male's seminal fluid belongs to liquefaction outside emitting body just the time, and in a short period of time, will be frozen into gelatin or the grumeleuse shape; About time of 10 ~ 30 minutes of warp; Seminal fluid just is liquefied as water sample liquid, and this process is exactly the liquefaction of seminal fluid, and this phenomenon belongs to normal physiological phenomenon.Excrete like seminal fluid, surpass 30 minutes and still be gelatin, then belong to pathologic condition, be called seminal fluid not liquefaction.The liquefaction that seminal fluid begins is for the ease of ejaculation; Then becoming gelatin is not flow out easily for seminal fluid can in vagina, be stopped; Later on liquefaction is in order to make the sperm in the seminal fluid fully movable again; So that move about to the fallopian tube position, be beneficial to smart ovum combination and fertilization along female genital tract.Seminal fluid not liquefaction usually influences the freely-movable of sperm.The seminal fluid that does not liquefy is agglomerating in the visible agglutination of spermatozoa of microscopically, stiff or slow wriggling only.The motion of sperm in this kind seminal fluid in female genital tract obviously hindered, sperm can not on be advanced into cervical canal, cavity of uterus and fallopian tube, can not meet with ovum, making fertilization that obstacle take place.Seminal fluid not liquefaction is the common cause that causes male infertility, has seriously perplexed the normal emotion life of a lot of patient family, usually causes conjugal relation nervous, even broken marriages.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition of treating seminal fluid not liquefaction.
For realizing above-mentioned purpose, the technical scheme that the present invention takes is following:
A kind of Chinese medicine composition of treating seminal fluid not liquefaction is processed by each crude drug of following portions by weight: 25 ~ 35 parts of Radix Salviae Miltiorrhizaes, 20 ~ 30 parts of Flos Loniceraes, 15 ~ 25 parts of Herba Epimedii, 5 ~ 15 parts of Radix Angelicae Sinensis, 10 ~ 20 parts in Radix Rehmanniae Preparata, 10 ~ 20 parts of the Radix Paeoniae Albas, 5 ~ 15 parts of Radix Paeoniae Rubra, 5 ~ 15 parts of the Rhizoma Anemarrhenaes, 5 ~ 15 parts of Cortex Phellodendris, 10 ~ 20 parts of Radix Trichosanthis, 10 ~ 20 parts of Semen Benincasaes, 5 ~ 15 parts of Fructus Lycii, 6 ~ 10 parts of Fructus Schisandrae Chinensis, 10 ~ 20 parts of Semen Cuscutae, 5 ~ 15 parts in Poria, 10 ~ 20 parts of Radix Polygoni Multiflori, 10 ~ 15 parts of Rhizoma Alismatis, 10 ~ 15 parts of Fructus Forsythiaes, 10 ~ 20 parts of Rhizoma Polygonatis, 5 ~ 15 parts of Cortex Moutans (another name Cortex Moutan), 10 ~ 20 parts of Carapax et Plastrum Testudiniss (another name Carapax Et Plastrum Testudinis), 5 ~ 15 parts of Rhizoma Cyperis, 4 ~ 8 parts in Radix Glycyrrhizae.
Optimum formula of the present invention is (weight portion): 30 parts of Radix Salviae Miltiorrhizaes, 25 parts of Flos Loniceraes, 20 parts of Herba Epimedii, 10 parts of Radix Angelicae Sinensis, 15 parts in Radix Rehmanniae Preparata, 15 parts of the Radix Paeoniae Albas, 10 parts of Radix Paeoniae Rubra, 10 parts of the Rhizoma Anemarrhenaes, 10 parts of Cortex Phellodendris, 15 parts of Radix Trichosanthis, 15 parts of Semen Benincasaes, 10 parts of Fructus Lycii, 8 parts of Fructus Schisandrae Chinensis, 15 parts of Semen Cuscutae, 10 parts in Poria, 15 parts of Radix Polygoni Multiflori, 12 parts of Rhizoma Alismatis, 12 parts of Fructus Forsythiaes, 15 parts of Rhizoma Polygonatis, 10 parts of Cortex Moutans, 15 parts of Carapax et Plastrum Testudiniss, 10 parts of Rhizoma Cyperis, 6 parts in Radix Glycyrrhizae.
Pharmacology of the present invention: Radix Salviae Miltiorrhizae is bitter, be slightly cold GUIXIN, Liver Channel, promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; Flos Lonicerae, sweet, cold, return lung, the heart, stomach warp, heat-clearing and toxic substances removing; Herba Epimedii, hot, sweet, warm, return liver, kidney channel, kidney-replenishing, bone and muscle strengthening, wind-damp dispelling; Radix Angelicae Sinensis, warm in nature, sweet in the mouth, suffering are returned liver, the heart, spleen channel, enrich blood invigorate blood circulation, loosening bowel to relieve constipation; Radix Rehmanniae Preparata, sweet, tepor is returned liver, kidney channel, the yin nourishing of enriching blood, life essence-filling, marrow-benefitting; The Radix Paeoniae Alba, liver, spleen channel are gone in picric acid, cold, and nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing are received antiperspirant; Radix Paeoniae Rubra is bitter, be slightly cold, return Liver Channel, clots absorbing, pain relieving, removing heat from blood, detumescence; The Rhizoma Anemarrhenae, bitter, sweet, cold, return lung, stomach, kidney channel, clearing away heat-fire, promote the production of body fluid and moisturize; Cortex Phellodendri, bitter, tremble with fear, return kidney, bladder, large intestine channel, heat clearing and damp drying, eliminating fire and detoxication; Radix Trichosanthis, is slightly cold at sweet, little hardship, attaches to the lung and stomach meridians clearing away heat and promoting production of body fluid, detumescence and apocenosis; Semen Benincasae, sweet, cool, return lung, large intestine channel, removing heat from the lung and dissipating phlegm, eliminating carbuncle evacuation of pus, dampness removing; Fructus Lycii, sweet in the mouth, property are put down, and return Liver Channel, kidney channel, lung meridian, nourishing the liver, nourishing kidney, lung moistening; Fructus Schisandrae Chinensis, lung, the heart, kidney channel are returned in temperature, acid, sweet, restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming; Semen Cuscutae, sweet, warm, return the liver,kidney,spleen warp, nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, make eye bright, antidiarrheal; Poria, the property slightly sweet flavor is flat, goes into the heart, lung, spleen channel, eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming; Radix Polygoni Multiflori, bitter in the mouth, sweet, puckery, slightly warm in nature are returned liver, kidney channel, nourishing the blood and yin, loosening bowel to relieve constipation, preventing the attack (or recurrence) of malaria, dispel the wind, detoxify; Rhizoma Alismatis, sweet, cold, return kidney, urinary bladder channel, diuresis, clearing away damp-heat; Fructus Forsythiae is bitter, be slightly cold heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, dispelling wind and heat pathogens; Rhizoma Polygonati, sweet, flat, return lung, spleen, kidney channel, nourishing kidney lung moistening, invigorating the spleen and replenishing QI; Cortex Moutan, is slightly cold GUIXIN, liver, kidney channel, clearing away heat and cooling blood, promoting blood circulation to remove blood stasis at bitter in the mouth, suffering; Carapax et Plastrum Testudinis, sweet salty, cold, return liver, kidney, heart channel, nourishing kidney YANG hyperactivity suppressing, replenishing kidney and strengthening bone, the reinforcing the heart of nourishing blood; Rhizoma Cyperi, hot little hardship is sweet, flat, goes into liver, tri-jiao channel, the resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving; Radix Glycyrrhizae, property is flat, sweet in the mouth, returns 12 warps, invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.More than all mutual compatibilities of medicine, play nourishing YIN to lower pathogenic fire, dissipating phlegm and removing blood stasis, the turbid effect of heat-clearing and toxic substances removing row altogether.
Method for preparing: can each crude drug of the present invention be processed any dosage form of acceptable clinically by conventional method.Such as: with each crude drug of the present invention by conventional method packing capsulae vacuus behind the porphyrize powder altogether, every capsules 0.5g.
The advantage of medicine of the present invention: row is turbid, evident in efficacy for nourishing YIN to lower pathogenic fire, dissipating phlegm and removing blood stasis, heat-clearing and toxic substances removing, and total effective rate reaches 96%.
The specific embodiment
Embodiment 1
By following weight, take by weighing each crude drug: Radix Salviae Miltiorrhizae 30g, Flos Lonicerae 25g, Herba Epimedii 20g, Radix Angelicae Sinensis 10g, Radix Rehmanniae Preparata 15g, Radix Paeoniae Alba 15g, Radix Paeoniae Rubra 10g, Rhizoma Anemarrhenae 10g, Cortex Phellodendri 10g, Radix Trichosanthis 15g, Semen Benincasae 15g, Fructus Lycii 10g, Fructus Schisandrae Chinensis 8g, Semen Cuscutae 15g, Poria 10g, Radix Polygoni Multiflori 15g, Rhizoma Alismatis 12g, Fructus Forsythiae 12g, Rhizoma Polygonati 15g, Cortex Moutan 10g, Carapax et Plastrum Testudinis 15g, Rhizoma Cyperi 10g, Radix Glycyrrhizae 6g.With above-mentioned each crude drug by conventional method packing capsulae vacuus behind the porphyrize powder altogether, every capsules 0.5g.
Embodiment 2
By following weight, take by weighing each crude drug: Radix Salviae Miltiorrhizae 25g, Flos Lonicerae 20g, Herba Epimedii 15g, Radix Angelicae Sinensis 5g, Radix Rehmanniae Preparata 10g, Radix Paeoniae Alba 10g, Radix Paeoniae Rubra 5g, Rhizoma Anemarrhenae 5g, Cortex Phellodendri 5g, Radix Trichosanthis 10g, Semen Benincasae 10g, Fructus Lycii 5g, Fructus Schisandrae Chinensis 6g, Semen Cuscutae 10g, Poria 5g, Radix Polygoni Multiflori 10g, Rhizoma Alismatis 10g, Fructus Forsythiae 10g, Rhizoma Polygonati 10g, Cortex Moutan 5g, Carapax et Plastrum Testudinis 10g, Rhizoma Cyperi 5g, Radix Glycyrrhizae 4g.With above-mentioned each crude drug by conventional method packing capsulae vacuus behind the porphyrize powder altogether, every capsules 0.5g.
Embodiment 3
By following weight, take by weighing each crude drug: Radix Salviae Miltiorrhizae 35g, Flos Lonicerae 30g, Herba Epimedii 25g, Radix Angelicae Sinensis 15g, Radix Rehmanniae Preparata 20g, Radix Paeoniae Alba 20g, Radix Paeoniae Rubra 15g, Rhizoma Anemarrhenae 15g, Cortex Phellodendri 15g, Radix Trichosanthis 20g, Semen Benincasae 20g, Fructus Lycii 15g, Fructus Schisandrae Chinensis 10g, Semen Cuscutae 20g, Poria 15g, Radix Polygoni Multiflori 20g, Rhizoma Alismatis 15g, Fructus Forsythiae 15g, Rhizoma Polygonati 20g, Cortex Moutan 15g, Carapax et Plastrum Testudinis 20g, Rhizoma Cyperi 15g, Radix Glycyrrhizae 8g.With above-mentioned each crude drug by conventional method packing capsulae vacuus behind the porphyrize powder altogether, every capsules 0.5g.
The observation on Clinical Application report:
One, basic document (in January, 2007 ~ 2011 year January)
accepts male patient's 121 examples, 25 ~ 40 years old age altogether for medical treatment.
Two, diagnostic criteria
After marriage more than 2 years, its wife's side gynecological each item inspection is all normal, love life together, and the person of not becoming pregnant, its liquefying time of the double seminal fluid chemical examination in the bridegroom's or husband's side is equal on inspection>1h person.
Three, criterion of therapeutical effect
Recovery from illness: liquefaction fully in the seminal fluid 60min, the spouse becomes pregnant;
Produce effects: conceived in March through treatment, seminal fluid 60min is liquefaction and sperm concentration, the more preceding improvement of vigor fully;
Effectively: through treatment, not conceived in March, seminal fluid 60min not exclusively liquefies, and sperm concentration, vigor before have certain improvement;
Invalid: no significant change before and after the treatment.
Four, Therapeutic Method
The capsule particle of the embodiment of the invention 1 preparation: every day three times, each 5, continued to take 1 ~ 2 month.
Five, therapeutic effect
Through treatment, 81 examples of fully recovering, produce effects 23 examples, effective 12 examples, invalid 5 examples, total effective rate is 96%.
Model case
Case 1
The Wang, the man, 36 years old, the patient tell 7 years after marriage sterile, the man and wife lives in together always after marriage, 2 times/week of sexual life, contraception, wife's gynecologial examination is no abnormal, tool fertility.Once in the row seminal fluid routine examination of how tame regular hospital, found seminal fluid not liquefaction, evolution is countless, but does not all have positive effect, with coming here to go to a doctor upon somebody's introduction.Take embodiment 1 capsule particle, every day three times, each 5, after continuing to take 2 months, the seminal fluid routine examination is normal, spends 2 months again, and the wife of phone announcement becomes pregnant.
Case 2
Liu so-and-so, the man, 34 years old, do not take any contraceptives sterile in 4 years after marriage, wife is no abnormal through gynecologial examination, has the normal fertile ability.Through the seminal fluid routine examination, find seminal fluid not liquefaction, the semen efamination report analysis: milky, amount 2.5ml, stickiness is high, 2 hours 10cm of wire drawing degree, pH value 7.5 is counted 8,800,000/ml, motility rate 81%, rectilinear motion accounts for 40% at a slow speed, and inactivity accounts for 60%.Take embodiment 2 capsule particles, every day three times, each 5, after continuing to take 2 months, the seminal fluid routine examination is normal, spends 3 months again, and wife becomes pregnant.
Case 3
Zhang, 25 years old, marry 3 years surplus, matrimonial cohabitation, sexual life is normal, contraception is not educated, wife's side inspection is normal.Once chemically examined seminal fluid conventional 3 times in certain hospital, all report: seminal fluid did not liquefy in 60 minutes.Take embodiment 3 capsule particles, every day three times, each 5, after continuing to take 1 month, recheck seminal fluid and show: liquefaction in 30 minutes, its wife is pregnant after January.
Claims (2)
1. a Chinese medicine composition of treating seminal fluid not liquefaction is characterized in that being processed by each crude drug of following portions by weight: 25 ~ 35 parts of Radix Salviae Miltiorrhizaes, 20 ~ 30 parts of Flos Loniceraes, 15 ~ 25 parts of Herba Epimedii, 5 ~ 15 parts of Radix Angelicae Sinensis, 10 ~ 20 parts of Radix Rehmanniae Preparata, 10 ~ 20 parts of the Radix Paeoniae Albas, 5 ~ 15 parts of Radix Paeoniae Rubra, 5 ~ 15 parts of the Rhizoma Anemarrhenaes, 5 ~ 15 parts of Cortex Phellodendris, 10 ~ 20 parts of Radix Trichosanthis, 10 ~ 20 parts of Semen Benincasaes, 5 ~ 15 parts of Fructus Lycii, 6 ~ 10 parts of Fructus Schisandrae Chinensis, 10 ~ 20 parts of Semen Cuscutae, 5 ~ 15 parts in Poria, 10 ~ 20 parts of Radix Polygoni Multiflori, 10 ~ 15 parts of Rhizoma Alismatis, 10 ~ 15 parts of Fructus Forsythiaes, 10 ~ 20 parts of Rhizoma Polygonatis, 5 ~ 15 parts of Cortex Moutans, 10 ~ 20 parts of Carapax et Plastrum Testudiniss, 5 ~ 15 parts of Rhizoma Cyperis, 4 ~ 8 parts in Radix Glycyrrhizae.
2. the Chinese medicine composition of treatment seminal fluid not liquefaction as claimed in claim 1 is characterized in that being processed by each crude drug of following portions by weight: 30 parts of Radix Salviae Miltiorrhizaes, 25 parts of Flos Loniceraes, 20 parts of Herba Epimedii, 10 parts of Radix Angelicae Sinensis, 15 parts of Radix Rehmanniae Preparata, 15 parts of the Radix Paeoniae Albas, 10 parts of Radix Paeoniae Rubra, 10 parts of the Rhizoma Anemarrhenaes, 10 parts of Cortex Phellodendris, 15 parts of Radix Trichosanthis, 15 parts of Semen Benincasaes, 10 parts of Fructus Lycii, 8 parts of Fructus Schisandrae Chinensis, 15 parts of Semen Cuscutae, 10 parts in Poria, 15 parts of Radix Polygoni Multiflori, 12 parts of Rhizoma Alismatis, 12 parts of Fructus Forsythiaes, 15 parts of Rhizoma Polygonatis, 10 parts of Cortex Moutans, 15 parts of Carapax et Plastrum Testudiniss, 10 parts of Rhizoma Cyperis, 6 parts in Radix Glycyrrhizae.
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| CN2011102369568A CN102284003B (en) | 2011-08-18 | 2011-08-18 | Traditional Chinese medicine composition for treating semen non-liquefaction |
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| CN2011102369568A CN102284003B (en) | 2011-08-18 | 2011-08-18 | Traditional Chinese medicine composition for treating semen non-liquefaction |
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| CN102284003B true CN102284003B (en) | 2012-07-25 |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104083509B (en) * | 2014-06-17 | 2016-05-11 | 刘海强 | A kind of Chinese medicine that is used for the treatment of nonliquefaction of semen |
| CN106266528A (en) * | 2015-05-23 | 2017-01-04 | 于振兰 | A kind of semen does not change disease medicine and compound method and detection method |
| CN105267594A (en) * | 2015-12-01 | 2016-01-27 | 山东群英医学研究有限公司 | Formula of traditional Chinese medicine for improving sperm activity |
| CN107890508A (en) * | 2017-11-20 | 2018-04-10 | 韩旻君 | It is a kind of to be used to treat Chinese medicine of disease of not liquefied sperm and preparation method thereof |
| CN109260315A (en) * | 2018-10-30 | 2019-01-25 | 广西中医药大学第附属医院 | It is a kind of for improving the pharmaceutical composition and preparation method of sperm quality |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1857621A (en) * | 2006-03-31 | 2006-11-08 | 南昌市医学科学研究所 | Capsule for treating acute and chronic prostatitis and its preparing process |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1857621A (en) * | 2006-03-31 | 2006-11-08 | 南昌市医学科学研究所 | Capsule for treating acute and chronic prostatitis and its preparing process |
Non-Patent Citations (1)
| Title |
|---|
| 姚重华,等.中医药治疗男性不育症研究进展.《山东中医杂志》.2006,第25卷(第3期),212-215. * |
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