CN102283952B - Bone strengthening and marrow increasing Chinese prepared medicine for treating bone diseases - Google Patents
Bone strengthening and marrow increasing Chinese prepared medicine for treating bone diseases Download PDFInfo
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Abstract
The invention discloses a bone strengthening and marrow increasing Chinese patent medicine for treating bone diseases. The bone strengthening and marrow increasing Chinese patent medicine comprises the following Chinese herbal medicines in part by weight: 20 to 40 parts of ginseng, 20 to 40 parts of rehmannia root, 20 to 40 parts of prepared rehmannia root, 20 to 40 parts of south dodder seed, 10 to 30 parts of epimedium, 20 to 40 parts of Chinese magnoliavine fruit, 20 to 40 parts of prepared polygonum multiflorum thumb., 20 to 40 parts of fortune's drynaria rhizome, 5 to 15 parts of liquoric root, 10 to 20 parts of hairy antler, 20 to 40 parts of bupleurum, 50 to 70 parts of astragalus, 10 to 15 parts of safranine and 90 to 120 parts of honey. The bone strengthening and marrow increasing Chinese patent medicine can be used for treating symptoms such as osteoporosis, protrasion of the lumbar intervertebral disci, delayed union of fracture, low immunity and the like, is definite in curative effect, convenient, low in cost, safe and reliable, and has a reasonable path for treating the bone diseases. The bone strengthening and marrow increasing Chinese patent medicine for treating bone diseases is obvious in a curative effect and convenient to use, addresses symptoms and root causes, and does not have pain and toxic or side effect in the treatment course.
Description
Technical field
The present invention relates to a kind of medicine of set a broken bone, particularly relate to a kind of bone strengthening for the treatment of osteopathia and increase the marrow Chinese patent medicine.
Background technology
In the daily life, osteopathia is a kind of commonly encountered diseases frequently-occurring disease, and osteopathia comprises osteoporosis, prolapse of lumbar intervertebral disc, fracture etc.
Existing bone healing method:
1, the operation of outer section connects (steel plate, intramedullary pin, external fixation of fracture frame etc.).
2, the bone-setting medicament of invigorating blood circulation is used.
3, the lighter's bone injury also has external application synthetism etc.Because having a big risk after the operation, expensive, patient's misery, union of fracture is slow, and even healing does not more very disable, and can form the fraud of curing the symptoms, not the disease.
Traditional Chinese medical science bone injury treatment by oral administration of medicines has long history and abundant clinical experience, yet treats at modern orthopaedics and traumatology under the background of westernization day by day, and traditional important bone injury treatment by oral administration of medicines is desalinated day by day.Therefore, cause many traditional medical units to use the also constantly atrophy for the treatment of by Chinese herbs bone injury, even abandoned, thereby cause the expense of bone healing also more and more higher, patient's burden is also more and more heavier.
For burden and the misery that alleviates patient, traditional Chinese medical science bone injury treatment by oral administration of medicines method needs further further investigation.Thereby in conjunction with abundant clinical experience, further development treatment osteopathia Chinese medicine evident in efficacy is very important.
At present, existing many about the patent documentation of set a broken bone aspect Chinese medicine, for example: 1, application number is 200810050339.7, the patent of invention name is called the patent of invention of " a kind of Chinese medicine preparation of set a broken bone disease ", the disclosed Chinese medicine preparation of this patent of invention is made up of Sanguis Draxonis, Flos Carthami, Eupolyphaga Seu Steleophaga, Pheretima, drynaria baronii, Olibanum, Myrrha, Radix Angelicae Sinensis, Lignum Sappan, the Cortex Eucommiae, Pyritum, Radix Dipsaci, Radix Paeoniae Rubra, Semen Melo etc., adopt traditional Chinese medicine processing technology to make medicament, be used for the treatment of explorative fracture, closed fracture, comminuted fracture etc.2, application number is that 200810106779.X, patent of invention name are called the patent of invention of " a kind of pharmaceutical composition for the treatment of osteoporosis ", and the pharmaceutical composition of this patent disclosure is made up of Monas cuspurpureus Went extract, Rhizoma Drynariae extract and Herba Epimedii extract.3, application number is 201010529167.9, denomination of invention is the patent of invention of " a kind of Chinese medicine formula for the treatment of prolapse of lumbar intervertebral disc ", and the disclosed Chinese medicine formula of this patent of invention is made up of Semen Juglandis, Semen Sesami Nigrum, the Cortex Eucommiae, Radix Dipsaci, Rhizoma Drynariae, Fructus Chaenomelis, Semen Cuscutae, Rhizoma Corydalis, Rhizoma Cyperi, Radix Angelicae Sinensis etc.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of bone strengthening for the treatment of osteopathia and increases the marrow Chinese patent medicine, utilizes the various osteopathia of Chinese patent drugs for treatment of the present invention, and is evident in efficacy, easy to use, treating both the principal and secondary aspects of a disease, and no pain in the therapeutic process, have no side effect.
In order to address the above problem, the technical solution used in the present invention is:
The invention provides a kind of bone strengthening for the treatment of osteopathia and increase the marrow Chinese patent medicine, represent that with weight portion described bone strengthening increases the marrow Chinese patent medicine and contains 90～120 parts of 20～40 parts of crude drug Radix Ginsengs, 20～40 parts of Radix Rehmanniae, 20～40 parts of Radix Rehmanniae Preparata, 20～40 parts of Semen Cuscutae, 10～30 parts of Herba Epimedii, 20～40 parts of Fructus Schisandrae Chinensis, 20～40 parts of Radix Polygoni Multiflori Preparata, 20～40 parts of Rhizoma Drynariae, 5～15 parts in Radix Glycyrrhizae, 10～20 parts in Cornu Cervi Pantotrichum, 20～40 parts of Radix Bupleuri, 50～70 parts of the Radixs Astragali, 10～15 parts of Stigma Crocis and Mel.
Bone strengthening according to above-mentioned treatment osteopathia increases the marrow Chinese patent medicine, and described bone strengthening increases the marrow Chinese patent medicine and contains 90～110 parts of 25～35 parts of crude drug Radix Ginsengs, 25～35 parts of Radix Rehmanniae, 25～35 parts of Radix Rehmanniae Preparata, 25～35 parts of Semen Cuscutae, 15～25 parts of Herba Epimedii, 25～35 parts of Fructus Schisandrae Chinensis, 25～35 parts of Radix Polygoni Multiflori Preparata, 25～35 parts of Rhizoma Drynariae, 8～12 parts in Radix Glycyrrhizae, 13～18 parts in Cornu Cervi Pantotrichum, 25～35 parts of Radix Bupleuri, 55～65 parts of the Radixs Astragali, 10～15 parts of Stigma Crocis and Mel.
Bone strengthening according to above-mentioned treatment osteopathia increases the marrow Chinese patent medicine, and described bone strengthening increases the marrow Chinese patent medicine and contains 90～110 parts of 28～32 parts of crude drug Radix Ginsengs, 28～32 parts of Radix Rehmanniae, 28～32 parts of Radix Rehmanniae Preparata, 28～32 parts of Semen Cuscutae, 18～22 parts of Herba Epimedii, 28～32 parts of Fructus Schisandrae Chinensis, 28～32 parts of Radix Polygoni Multiflori Preparata, 28～32 parts of Rhizoma Drynariae, 8～12 parts in Radix Glycyrrhizae, 14～16 parts in Cornu Cervi Pantotrichum, 28～32 parts of Radix Bupleuri, 58～62 parts of the Radixs Astragali, 11～13 parts of Stigma Crocis and Mel.
Bone strengthening according to above-mentioned treatment osteopathia increases the marrow Chinese patent medicine, and described Radix Ginseng is the Changbai Mountain Radix Ginseng; Described Fructus Schisandrae Chinensis is the distant five tastes; Described Radix Glycyrrhizae is Radix Glycyrrhizae Preparata.
Bone strengthening according to above-mentioned treatment osteopathia increases the marrow Chinese patent medicine, and the dosage form that the bone strengthening of described treatment osteopathia increases the marrow Chinese patent medicine is pharmaceutically acceptable dosage form.
Bone strengthening according to above-mentioned treatment osteopathia increases the marrow Chinese patent medicine, and the dosage form that the bone strengthening of described treatment osteopathia increases the marrow Chinese patent medicine is water preparation.
Bone strengthening according to above-mentioned treatment osteopathia increases the marrow Chinese patent medicine, and the preparation method of described water preparation is:
A, the crude drug proportioning that increases the marrow Chinese patent medicine according to the bone strengthening of above-mentioned treatment osteopathia take by weighing various crude drug, at first crude drug Radix Ginseng, Radix Rehmanniae, Radix Rehmanniae Preparata, Semen Cuscutae, Herba Epimedii, Fructus Schisandrae Chinensis, Radix Polygoni Multiflori Preparata, Rhizoma Drynariae, Radix Glycyrrhizae, Cornu Cervi Pantotrichum, Radix Bupleuri, the Radix Astragali and Stigma Croci are placed marmite, the water that adds 6～9 times of various crude drug gross weights then soaks, and soak time is 12～16 hours;
B, various crude drug boil it after soaking, and change slow fire after boiling into and boil 50～70 minutes, filter after boiling, and obtain first-time filtrate; Medicine after will filtering then adds the water that accounts for 6～9 times of medicine gross weights and boils, and changes slow fire after boiling into and boils 50～70 minutes, carries out the second time and filters, and obtains secondary filtrate after the filtration;
C, the medicine behind the step b secondary filter is added the water account for 6～9 times of medicine gross weights boil, changing slow fire after boiling into boiled 90～100 minutes, filter for the third time after boiling, obtain filtrate three times, will be through the filtrate mix homogeneously of three filtrations, the container after the medicinal liquid with mix homogeneously places totally, sterilizes then left standstill 12～14 hours, leaving standstill the back filters with filter cloth, obtain supernatant, the gained supernatant is boiled to aequum with slow fire, obtain required medicinal liquid;
D, step c to be boiled the medicinal liquid that obtains be that the ratio of 1:1 adds Mel according to weight ratio, will add medicinal liquid branch behind the Mel then and pack into and carry out autoclaving in the vial, and sterilization is afterwards stand-by.
The bone strengthening that the present invention treats osteopathia increases marrow Chinese patent medicine water preparation, and every bottle of 500mL of packing takes 15mL at every turn, every day 3 times, one after each meal.
The pharmacological action of the various crude drug of the present invention:
Radix Ginseng: warm in nature, sweet in the mouth, little hardship; Go into spleen, lung two warps.Effect cures mainly: 1, QI invigorating emergency treatment of collapse: the Radix Ginseng strongly invigorating primordial QI, training is solid basic, so the effect of the collapse of saving is arranged.2, calm the nerves and throb with fear surely: the Radix Ginseng tonifying five ZANG-organs, peace spirit is decided soul, and spasmolytic is throbbed with fear.3, training fills blood: ginseng qi-tonifying is enriched blood, the reinforcing primordial QI reinforcing.4, helping inspiration to relieve asthma: Radix Ginseng abnormal smells from the patient gentleness, lung kidney two is mended, and the only effect of dyspnea due to deficiency is arranged.5, promoting the production of body fluid to quench thirst: Radix Ginseng is controlled the thirsty hyperhidrosis due to two wounds of gas Tianjin, shortness of breath and tired spirit etc., and as the calentura later stage, hinder in gas Tianjin two, or internal injury is with the passing of time, and functional activities of the body fluid is impaired, all sees this card, reuses Radix Ginseng, but the effect that income gas promotes the production of body fluid.6, invigorating the spleen and replenishing QI.7, kidney tonifying complement: the Radix Ginseng strongly invigorating primordial QI, add spirit, born fluid, prolonged illness unit void must be used the person of taking off, and desires to rescue the person's of rebuilding one's physical constitution informal dress after being ill, and cards such as the double sexual impotence of controlling instability of kidney QI, seminal emission, spermatorrhea all rely the merit of its strengthening by means of tonics.8, strengthening body resistance and dispelling evil.
Radix Rehmanniae: sweet in the mouth, hardship, cold in nature; Go into the heart, liver, kidney three warps.Effect cures mainly: this product sweet-bitter flavor, cold in nature and go into blood system, clearing away heat and cooling blood.Cure mainly fever due to yin deficiency, quench one's thirst, spit blood, epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon is hindered constipation.
Radix Rehmanniae is the rhizome of scrophulariaceae rehmannia glutinosa plant, sweet in the mouth and hardship, GUIXIN, liver, kidney channel have clearing away heat and cooling blood, yin nourishing, a function of promoting the production of body fluid, and are used for that calentura, crimson tongue excessive thirst tongue, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency are quenched one's thirst, haematemesis, menoxenia, frequent fetal movement, the moon hinder diseases such as constipation.
The sweet Han Zhirun of Radix Rehmanniae, both kind removing heat from blood purged heat, again kind YIN nourishing and the production of body fluid promoting.All blood systems have heat and all dirty Tianjin impairment of YIN deficiency persons, are product commonly used.
Radix Rehmanniae Preparata: slightly warm in nature, sweet in the mouth; Go into the heart, liver, stomach three warps.Effect cures mainly: 1, nourishing the kidney and liver: the Radix Rehmanniae Preparata darkish complexion, blackly can go into kidney, and spermatogenesis is mended marrow, be the key medicine of enriching blood again, blood stored in the liver, enriching blood is the body of the liver benefiting, and The liver and the kidney have a common source, and essence and blood is changed mutually, and seminal emission, hectic fever, essence and blood two empty diseases are so Radix Rehmanniae Preparata has the effect of nourishing the kidney and liver.Asthenia interior-heat, lumbago due to renal deficiency, the deficiency of liver-blood hypochondriac pain controlled commonly used.2, deficiency of YIN cough with asthma: this product darkish complexion, go into kidney channel, for the key medicine of nourishing kidney yin, because of kidney governing inspiration, if the kidney loss, gas loses to take the photograph and receives and superinverse, and causes cough and asthma.Available Radix Rehmanniae Preparata improving inspiration by invigorating the kidney.3, quench one's thirst: the plain body deficiency of YIN, multiple excessive because of the labor desire, more consume cloudy Tianjin, damage of kidney-YIN, hyperactivity of fire caused by deficiency of YIN, the lung gold that upward burns causes then and suffers from a deficiency of the kidney and the dryness of the lung, sends out to quenching one's thirst.Insufficiency of kidney-YANG, urinary micturition, muddy as fat, or urinate sweet, dry mouth and tougue, red tongue, deep pulse is counted accurately, first-selected Radix Rehmanniae Preparata, enriching yin and nourishing kidney are quenched one's thirst from only.4, tonifying blood and regulating menstruation: the Radix Rehmanniae Preparata sweet in the mouth, warm in naturely go into the Liver and kidney warp, sweet can the benefit, Wen Nengtong, menstruation comes from the sea of blood, catharsis regularly, normally whether, relevant with Liver and kidney, so Radix Rehmanniae Preparata, nourishing blood for regulating menstruation is considered as panacea.Amenorrhea, metrorrhagia, the puerperal abdonimal pain controlled commonly used.
Semen Cuscutae: property is flat, sweet in the mouth, suffering; Go into liver, kidney two warps.Effect cures mainly: 1, tonifying the kidney to consolidate the essence: the Semen Cuscutae acrid-sweet flavor, property is flat, for the medicine of flat benefits, goes into kidney channel, i.e. kidney-replenishing, tonifying kidney-yin again, clothes energy controlling nocturnal emission with astringent drugs reducing urination.Clinically be used for the treatment of the pain in the lumbar region of suffering from a deficiency of the kidney, impotence and seminal emission, incontinence of urine, the heeltap in the urine, the not solid disease of essence of suffering from a deficiency of the kidney such as quench one's thirst more.2, tonifying liver makes eye bright: the panacea of the positive reinforcing the heart of Semen Cuscutae, liver, kidney, condition be assorted not flavor again, and then power is special especially, so can directly go into three warps to receive effect also.Clinical many orders with this product treatment insufficiency of blood are dark.3, spleen reinforcing antidiarrheal.4, solid and gas is prevented miscarriage: Semen Cuscutae is the agent of single benefit.Go into Liver and kidney two warps, the kidney invigorating nourishing the liver, blood stored in the liver, kidney storing essence, essence and blood sharing the same origin, the essence and blood abundance, then tire is foster to some extent, so, deficiency of the liver and kindey, liability to abortion, available Semen Cuscutae primordial QI reinforcing is prevented miscarriage.
Herba Epimedii: warm in nature, acrid in the mouth, sweet is nontoxic; Go into liver, kidney two warps.Effect cures mainly: 1, reinforcing the kidney and supporting YANG: Herba Epimedii is warm in nature cold, the beneficial vital essence of energy, and the insufficiency of kidney-YANG person should it.So the sexual impotence for the treatment of insufficiency of kidney-YANG commonly used, seminal emission, the enuresis, diseases such as frequent micturition.2, strengthening the tendons and bones: the sweet temperature of Herba Epimedii is mended partially, goes into the Liver and kidney warp, the energy liver and kidney tonifying, and muscle is good for bone, so the fistula of available treatment deficiency of both the liver and kidney is useless.3, expelling wind and removing dampness: the hot using warming therapy product of Herba Epimedii, Gu kidney-reinforcing Yang-strengthening not only, and the pathway that can pass through, the removal anemofrigid-damp arthralgia.Clinical available dispelling the wind and dampness pathogens arthralgia pain and cold-damp are pented up diseases such as spasm of the limbs.4, wash the skin ulcer parasite killing.5, the scrofula carbuncle that disappears.
Fructus Schisandrae Chinensis: warm in nature; Sour in the mouth, sweet.Go into lung, stomach, the heart three warps.Effect cures mainly: the nourishing kidney of 1, astringing the lung: this product acid can restrain, and is warm in nature and moisten, and goes into lung, kidney channel, on the gas of astringing the lung, following nourishing kidney-yin is applicable to breathing with cough of chronic cough of deficiency lung and lung kidney deficiency, and the effect of relieving cough and asthma is arranged.2, the arresting sweating that promotes the production of body fluid: Fructus Schisandrae Chinensis Gan Suanhuayin, can mend, can promote the production of body fluid, go into cardiopulmonary through, lung benefiting the moon, hold back the heart-yin and hidroschesis.Be applicable to that Tianjin wound is thirsty, spontaneous perspiration, night sweat, card such as quench one's thirst.3, arresting seminal emission antidiarrheal: the sweet acid of Fructus Schisandrae Chinensis, go into kidney channel.Sweet in the mouth can be mended, and calculation can be held back puckery, so the kidney invigorating arresting seminal emission is arranged, the effect of astringing to arrest diarrhea.Available controlling suffered from a deficiency of the kidney essence not admittedly, the puckery disease of back the moon, as: cards such as seminal emission, spermatorrhea, incessant chronic diarrhea.4, mind tranquilizing and the heart calming: the sweet acid of Fructus Schisandrae Chinensis, go into the heart, kidney two warps, the moon that can beneficial heart kidney and mind tranquilizing and the heart calming.The cards such as cardiopalmus, insomnia, dreaminess, irritability of controlling commonly used.
Radix Polygoni Multiflori Preparata: bitter in the mouth, sweet, puckery is warm in nature flat.Have enrich and benefit essence and blood, nourishing the liver is calmed the nerves, bone and muscle strengthening, and the crow palpus that reinforces the kidney is seen Light-headedness for blood deficiency, and palpitation and insomnia is forgetful, and is sallow weak, and the Liver and kidney essence and blood loses empty vertigo and tinnitus, soreness of the waist and knees, seminal emission metrorrhagia and leukorrhagia, diseases such as early whitening of beard and hair.
Rhizoma Drynariae: warm in nature, bitter in the mouth, go into liver, kidney two warps.Effect cures mainly: 1, the kidney invigorating: the bitter temperature of Rhizoma Drynariae is gone into liver, kidney two warps, and the merit of the kidney invigorating is arranged.Cards such as the lumbago due to clinical treatment commonly used is suffered from a deficiency of the kidney, tinnitus, deafness, toothache, chronic diarrhea.2, invigorate blood circulation, continue and hinder pain relieving: the bitter temperature of this product, hardship can be rushed down can be dry, and Wen Nengtong can loose.The kidney invigorating is gone in the osteomiosis the kidney invigorating, and invigorating middle warmer has row, in the row benefit is arranged, so the merit of invigorating blood circulation, continuing wound, pain relieving is arranged.Clinical treatment traumatic injury commonly used, arthralgia pain, cards such as acute appendicitis.3, alopecia areata: the bitter temperature of Rhizoma Drynariae is gone into Liver and kidney, and the merit of the alopecia areata of controlling is arranged.4, clavus: Rhizoma Drynariae has the effect of the clavus of controlling.
Radix Glycyrrhizae: property is flat, sweet in the mouth; Go into the heart, lung, spleen, stomach four warps.Effect cures mainly: Radix Glycyrrhizae has invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the effect of coordinating the actions of various ingredients in a prescription.Be usually used in weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Cornu Cervi Pantotrichum: slightly warm in nature, sweet in the mouth, salty, sour, nontoxic; Go into liver, kidney two warps.Effect cures mainly: 1, reinforcing the kidney and supporting YANG: the sweet temperature of Cornu Cervi Pantotrichum, go into kidney channel, and kidney-replenishing, strong governor vessel is the tonifying YANG Conclusion Decreasing, the key medicine of supplying vital essence and marrow, so the clinical treatment impotence and premature ejaculation of using, cold womb is infertile, emission and spermatorrhea more, enuresis frequent micturition, Hiccough and deaf, the deficiency and coldness disease of insufficiency of kidney-YANG such as have loose bowels.2, spermatogenesis bone strengthening: Cornu Cervi Pantotrichum is the essence of flesh and blood, goes into liver, kidney two warps, the energy invigorating the liver and kidney, and kidney storing essence master bone, blood stored in the liver master muscle, thus benefiting essence-blood is arranged, the merit of bone and muscle strengthening, available treatment asthenia is won thin, and order is secretly dizzy, the diseases such as the soft walking retardation in children of withering.3, accent dashes to appoint and only collapses: Cornu Cervi Pantotrichum has liver and kidney tonifying, the merit of Chong and Ren Meridians regulating, thus available treating the liver kidney deficiency, the debility of CHONG and REN meridians, extreme cold of the limbs is through the black metrostaxis disease of polychrome.4, the cold leukorrhagia stopping of temperature: Cornu Cervi Pantotrichum energy warming and recuperating the kidney-YANG, so Chong and Ren Meridians regulating is available treatment deficiency and coldness leukorrheal diseases.5, promoting pus discharge and tissue regeneration strengthening: the sweet temperature of Cornu Cervi Pantotrichum can replenishing vital essence and blood.The network of promoting blood circulation warm in nature, thus also can burst for a long time and do not hold back or disease that carbuncle of yin nature can not cave in controlling skin infection, with the pus expelling by strengthening vital QI granulation promoting.
Radix Bupleuri: cool in nature, bitter in the mouth, go into percardium, liver, gallbladder, three warmers.Effect cures mainly: 1, treating SHAO YANG disease by mediation: Radix Bupleuri is bitter cool, goes into shaoyang channel.Radix Bupleuri is the special medicine of few sun, and makings is gently clear, and bitterness is the thinnest, and is evil outside the expelling heat from the exterior half exterior and half interior, makes from outer solution.So the effect for the treatment of SHAO YANG disease by mediation is arranged.2, soothing liver-QI stomach function regulating: the cold of Radix Bupleuri toil, go into the liver and gall tri-jiao channel, so the effect of soothing liver-QI stomach function regulating is arranged, be usually used in stagnation of QI in chest and abdomen, diet gathers, and pushes away Chen Zhixin, hypochondriac pain abdominal distention.3, ascending up spleen-Qi and Yang: Radix Bupleuri, property is gently clear, and main the liter loose.So the effect of ascending up spleen-Qi and Yang is arranged.The cards such as deficiency of spleen-QI and stomach-QI, sinking of QI of middle-JIAO of controlling commonly used.4, dispersing the stagnated live-QI to relieve the stagnation of QI: the Radix Bupleuri bitter in the mouth is cool in nature, goes into Liver Channel.So this product can reach irritability and dispersing the stagnated live-QI to relieve the stagnation of QI by bar.The available cards such as melancholia, irregular menstruation, invasion of the blood-chamber by heat of controlling.5, clearing ministerial fire: Radix Bupleuri is bitter cool, then can clearing away heat-fire, go into the liver and gall tri-jiao channel, and then can clearing ministerial fire.Be usually used in headache, dizzy, cards such as blurred vision is hidden from view, Hiccough and deaf.6, the eliminating impediment that dispels the wind: Radix Bupleuri is the wind medicine, and wind being the primary exopathogen, wind go then to wet.So the effect of the eliminating impediment of dispeling the wind is arranged.
The Radix Astragali: slightly warm in nature, sweet in the mouth; Go into lung, spleen two warps.Effect cures mainly: 1, tonifying Qi and lifting yang: the sweet temperature of the Radix Astragali, sweet can the benefit has the strengthening by means of tonics effect.Key medicine for QI invigorating.Have air making-up and spleen enlivening, benefiting qi and raising yang, invigorating middle warmer is supporing yang, the effect of qi-supplementing, blood-engendering.2, hemostasis by invigorating QI: the Radix Astragali commonly used is controlled because of deficiency of spleen-QI various hemorrhage that blood causes of can not uniting, and when massive hemorrhage, tangible blood can not speed be given birth to especially, and invisible gas work as urgency admittedly.Reuse the Radix Astragali this moment, can receive the special effect of hemostasis hemopoietic.3, the QI invigorating row stagnate, eliminating stasis and resolving masses: the then not all right and stasis of blood resistance of blood of the stagnation of QI, disease is seen numb limbs and tense tendons, arthralgia, hemiplegia, the side of body uncomfortable in chest is opened, dim complexion, purplish tongue or petechia is arranged, ecchymosis, deep and hesitant pulse is used Radix Astragali benefiting qi and nourishing blood, can receive the effect of eliminating stasis and resolving masses.4, benefiting QI for strengthening the superficies: the sweet temperature of the Radix Astragali, the gas of main tonifying the lung spleen, lung qi is prosperous, then the solid perspiration stopped of table.5, QI invigorating tonifying YIN: with Radix Astragali tonification gas the moon, receive strengthening the spleen and stomach, cloth body fluid, secret controlling nocturnal emission with astringent drugs gas and the victory effect of hidroschesis contracting spring.6, inducing diuresis to remove edema.7, warming the interior cold expelling: Radix Astragali sweet in the mouth and temperature, with controlling arthralgia due to stagnation of blood, very with through justice.8, pus expelling by strengthening vital QI granulation promoting: Radix Astragali master carbuncle, lose skin ulcer for a long time, the evacuation of pus pain relieving, the insane disease of strong wind, five anal fistula are persons particularly liable to develop skin infection's key medicine.9, strong body constitution, life lengthening.
Stigma Croci: property is flat, sweet in the mouth; Go into the heart, liver two warps.Effect cures mainly: 1, blood circulation promoting and blood stasis dispelling: this medicine color is red, goes into the conscience warp, and sweet in the mouth is cold, enriches blood and invigorates blood circulation, blood stasis dispelling easing the affected liver, the merit of removing pathogenic heat from blood and toxic substance from the body.Be usually used in married woman's amenorrhea, postnatal blood stasis stomachache, treating swelling and pain by traumatic injury, typhoid fever multiple disease such as go mad.2, dispersing stagnation and relieving accumulation of pathogens: the Stigma Croci nature and flavor are sweet to be increased, and goes into liver heart channel, is good at blood circulation promoting and blood stasis dispelling, the dispersing the stagnated live-QI to relieve the stagnation of QI regulating QI to relieve pain.Be usually used in the pent-up of being worried, the chest and diaphragm feeling of fullness, palpitation with fear is in a trance, diseases such as breast side of body feeling of distension and oppression.
Mel: property is flat, sweet in the mouth; Go into lung, spleen, large intestine three warps.Effect cures mainly: 1, invigorating the spleen and replenishing QI: this product sweet in the mouth is flat, goes into the taste warp, and The spleen and stomach provide the material basis of the acquired, source of generating QI and blood.The sugariness master mends, so but tonifying the spleen and stomach, replenishing QI and blood.Be applicable to sinking of QI of middle-JIAO, diseases such as taste QI and blood.2, relieving spasm to stop pain: this product sweet in the mouth so can relax contracture pain, is applicable to gastralgia, colic of cold type stomachache, diseases such as wind and cold arthralgia pain.3, nourishing the lung to arrest cough: this product sweet in the mouth matter profit, people's lung meridian, it is dry to be longer than taste, so can moisten the respectful machine that falls of lung.Be applicable to dryness of the lung dry cough, diseases such as chronic cough of deficiency lung.4, loosening bowel to relieve constipation: the sliding matter profit of Mel, go into large intestine channel, so moisturize laxation, with softening stool, be easy to discharge.Be applicable to that Tianjin is withered due to old, weak, prolonged illness, puerperal, the deficiency of YIN, diseases such as blood deficiency and constipation.
It is main Therapeutic Principle with invigorating the kidney and strengthening the bones, invigorating the spleen and benefiting QI, promoting blood circulation to remove obstruction in the collateral that the bone strengthening that the present invention treats osteopathia increases marrow Chinese patent medicine prescription, Herba Epimedii, Cornu Cervi Pantotrichum kidney invigorating and YANG supporting in the side; Semen Cuscutae, Radix Polygoni Multiflori Preparata replenishing kidney-YIN, life essence-filling, marrow-benefitting, strong waist knee joint; Rhizoma Drynariae the kidney invigorating bone strengthening; Changbai Mountain Radix Ginseng, Radix Astragali spleen invigorating QI invigorating; Radix Rehmanniae, Radix Rehmanniae Preparata and Stigma Croci are enriched blood and are invigorated blood circulation, promoting tissue regeneration by removing blood stasis.Treatment must aim at the pathogenesis of disease, prescription of the present invention is from the angle of etiology and pathogenesis, the kidney invigorating void, strengthening bone and muscle, invigorating the spleen and benefiting QI, promoting blood circulation to remove obstruction in the collateral, bone is filled to some extent, marrow is changed to some extent, and muscle is foster to some extent, and channels is common, the stasis of blood is gone swollen disappearing, so the various blood stasis due to renal deficiency diseases that cause for osteoporosis, prolapse of lumbar intervertebral disc, fracture and immunologic hypofunction all have good efficacy.
Positive beneficial effect of the present invention:
1, Chinese patent medicine of the present invention can be used for treating diseases such as osteoporosis, prolapse of lumbar intervertebral disc, fracture delayed union person, immunologic hypofunction.Utilizing the various osteopathia determined curative effects of Chinese patent drugs for treatment of the present invention, convenient cheap, safe and reliable, is a kind of method of approach proper treatment osteopathia.
2, utilize Chinese patent drugs for treatment osteoporosis of the present invention to have significant curative effect, the treatment effective percentage reaches more than 90%.
Utilize the clinical data of Chinese patent drugs for treatment patients with osteoporosis of the present invention:
Include primary osteoporosis patient 665 examples (men and women does not limit) that meet selected condition in, the age was taken Chinese patent drugs for treatment of the present invention voluntarily between 50～75 years old.Adopt the randomized controlled test method(s), 665 routine patients with osteoporosis are divided into treatment group and matched group with the ratio of 3:1, and wherein 500 examples are organized in treatment, matched group 165 examples, two groups of patients all do not have significant difference on the duration of symptoms before age, sex, treatment, have comparability.
The standard of selected patients with osteoporosis:
The patients with osteoporosis MethodsThe cases enrolled all meets Chinese gerontology and understands osteoporosis committee diagnosing osteoporosis standard, " Chinese's osteoporosis suggestion diagnostic criteria (the 2nd original text) " [Chinese osteoporosis magazine of subject group formulation on October 22nd, 1999,2000 the 6th the 1st phases of volume, 1-3 page or leaf] and the clinical research guideline of osteoporosis " new Chinese medicine treat " in the diagnostic criteria of primary osteoporosis.
Diagnostic criteria: bone mineral content diagnostic criteria and peak bone density are lost percentage rate and grade scale (be mainly used in the women adult, the male consults and carries out).
(1), with reference to the standard of The World Health Organization (WHO), work out this standard in conjunction with China's national situation, measure peak bone amount (M ± SD) with the women of Han nationality dual energy X-ray absorptiometry (DEXA method).The bone amount (M ± SD) is normal reference value, is not still having under the situation of segmentation criteria different nationalities, area and sex this standard of can consulting and carrying out at present:
M-lSD is normal; M-lSD～2SD reduces for the bone amount;＜M-2SD is above to be osteoporosis;＜M-more than the 2SD, and with a place or multiple fracture, be serious osteoporosis; The above nothing fracture of＜M-3SD, also diagnosable is serious osteoporosis.Tcm diagnosis meets this disease deficiency complicated with excess, to suffer from a deficiency of the kidney and the syndrome of blood stasis shows as diagnosis basis.Clinical manifestation is: soreness of the waist and knees, backache, aversion to cold and cold limbs, especially with lower limb for very, have a dizzy spell, lethargy, pale complexion, the fat tongue of light red tongue is white, deep and weak pulse.
(2), with reference to the standard of Japan's revised edition in 1996, do not make the peak bone density survey as yet, when SD inconvenience is used, available lumbar vertebra bone loss percentage rate (%) method of diagnosis:
M-l2 is normal; M-13%～24 reduces for the bone amount;＜M-25 is osteoporosis;＜M-25 is serious osteoporosis with a place or multiple fracture;＜M-37 does not have fracture, and also diagnosable is serious osteoporosis.
(3), exclusion standard: selected patient all gets rid of other diseases, as merge to have the inclination, serious primary disease persons such as cerebrovascular, liver, kidney and hemopoietic system, to the known composition allergy sufferers of this medicine, the state of an illness is critical, spinal tuberculosis or tumor person and participated in other clinical trial persons in nearly 1 month.
(4), Therapeutic Method:
Patients with osteoporosis treatment group is all taken the bone strengthening that the present invention treats osteopathia and is increased marrow Chinese patent medicine water preparation, i.e. the bone strengthening that the present invention is made by Radix Ginseng, Radix Rehmanniae, Radix Rehmanniae Preparata, Semen Cuscutae, Herba Epimedii, Fructus Schisandrae Chinensis, Radix Polygoni Multiflori Preparata, Rhizoma Drynariae, Radix Glycyrrhizae, Cornu Cervi Pantotrichum, Radix Bupleuri, the Radix Astragali, Stigma Croci and Mel increases marrow Chinese patent medicine water preparation.Water preparation packing specification is every bottle of 500mL, instructions of taking: each 15 mL, and every day 3 times, one after each meal, 24 weeks were a course for the treatment of.
The patients with osteoporosis matched group is taken GUSONGBAO capsule (pharmaceutcal corporation, Ltd provides by the Guizhou Fuhua).Authentication code: [the accurate word of traditional Chinese medicines medicine] z20030084.Lot number: 07041S.Instructions of taking: each 2, every day 3 times, warm water delivery service after meal.24 weeks were 1 course for the treatment of.
(5) observation and curative effect:
Criterion of therapeutical effect:
Produce effects: lumbago and backache disappears, and spinous process does not have the pain of kowtowing, and bone density increases, and activity can be engaged in original work freely, does not recur after 1 year with examining;
Effectively: lumbago and backache is clearly better, and activity is normal substantially, can be engaged in lighter work, and the state of an illness has repeatedly;
Invalid: lumbago and backache does not have alleviation, and spinous process is kowtowed pain, and bone density does not have change.
Total effective rate=produce effects+effectively.
Observation index: all adopt the Korea S EXA one 3000 instant imaging bone density of dual intensity X line (stone age) measuring instruments (The Evolution of X-ray Absorptiometry) ~ lJ before and after the treatment, check that patient's lumbar vertebra (L 2～L 4 anteroposterior positions) bone density value compares curative effect.Safety indexes: blood pressure, heart rate inspection before and after the treatment; Blood, urine, stool routine inspection; Liver, kidney function test.
(6) observed result:
The health giving quality analysis result:
Detailed being shown in Table 1, treated for 24 weeks after, the bone density rate of change relatively, two groups of total effective rates differ from 95%, the credibility interval is 2.75%～20.42%.PP analyzes and FAS analysis result basically identical.The bone strengthening that proof the present invention treats osteopathia increases the marrow Chinese patent medicine and is better than the GUSONGBAO capsule for the bone density of improving patients with osteoporosis.Traditional Chinese medical science total effects compares, and the result is detailed to be shown in Table 2, and compares between two groups of apparent rates of control (control shows the routine number of rate=produce effects/total routine number) and total effective rate (total effective rate=total routine number-invalid routine number/total routine number) group, and difference has statistical significance (P=0.0030).Two groups of total effective rates differ from 95%, and the credibility interval is 12.55%～23.56%.PP analyzes and FAS analysis result basically identical.The bone strengthening that proof the present invention treats osteopathia increases marrow Chinese patent drugs for treatment osteoporosis clinical efficacy and is better than the GUSONGBAO capsule.
Table 1 treatment group and matched group bone density curative effect are relatively
Table 2 matched group and treatment group clinical efficacy are relatively
The safety analysis result: patient's vital sign comprises blood pressure, heart rate, body temperature and preceding comparison after taking Chinese patent medicine of the present invention, has no significant change, and does not also have the change that clinical meaning is arranged.The result shows to laboratory safety inspection index analysis, and the patient does not all find blood, urine, stool routine examination after taking Chinese patent medicine of the present invention, and liver, renal function and electrocardiogram have the change of clinical meaning.
3, utilize Chinese patent drugs for treatment prolapse of lumbar intervertebral disc of the present invention to have significant curative effect, the treatment effective percentage reaches more than 90%.
Utilize the clinical data of Chinese patent drugs for treatment patients with lumbar disc herniation of the present invention:
Choose patients with lumbar disc herniation 500 examples in year May in May, 2006 to 2009, male 363 examples, women 137 examples; Minimum 25 years old of age, maximum 72 years old, average 46 years old; 20 days 150 examples of the course of disease, 2 years 350 examples." traditional Chinese medical science disease diagnosis criterion of therapeutical effect " that all meets State Administration of Traditional Chinese Medicine's issue in 1994.
The diagnostic criteria of prolapse of lumbar intervertebral disc: 1. waist wound, chronic strain are arranged or be subjected to the cold-damp history.Most of patient has the chronic back pain history at premorbid.2. often betide person between twenty and fifty.3. lumbago is to buttocks and lower limb radiation, and pain increased the weight of when abdominal pressure increased (as cough, sneeze).4. scoliosis, the waist physiologic radian disappears, and the diseased region vertebra is other tenderness, and to lower limb radiation, waist limitation of activity.5. the lower limb innervation district that gets involved feels irritatedly or blunt, and amyotrophy can appear in course of disease length.Straight lower limb is raised or is strengthened the test positive, and knee joint, Achilles tendon reflex weaken or disappear, and the big toe back of the body power of stretching weakens.6. line is taken the photograph the sheet inspection and is shown scoliosis, and waist physiology lordosis disappears, and neighboring edge has osteophytosis.CT, MRI check position and the degree that can show intervertebral disk hernia.Chinese medical discrimination belongs to deficiency of the kidney, phlegm stagnation in collateral.Card is seen lumbago, and to buttocks and lower limb radiation, pain increases the weight of when cough or sneeze, companion's soreness of the waist and knees, or numbness of lower limbs, light red tongue, white and thin fur, thready pulse.
Therapeutic Method: patients with lumbar disc herniation is taken the bone strengthening that the present invention treats osteopathia and is increased marrow Chinese patent medicine water preparation, i.e. the bone strengthening that the present invention is made by Radix Ginseng, Radix Rehmanniae, Radix Rehmanniae Preparata, Semen Cuscutae, Herba Epimedii, Fructus Schisandrae Chinensis, Radix Polygoni Multiflori Preparata, Rhizoma Drynariae, Radix Glycyrrhizae, Cornu Cervi Pantotrichum, Radix Bupleuri, the Radix Astragali, Stigma Croci and Mel increases marrow Chinese patent medicine water preparation.Water preparation packing specification is every bottle of 500mL, instructions of taking: each 15ml, every day 3 times, one after each meal.30 days is a course for the treatment of.
Criterion of therapeutical effect: according to " traditional Chinese medical science disease diagnosis criterion of therapeutical effect " of State Administration of Traditional Chinese Medicine's issue in 1994.Clinical cure: lumbago and skelalgia disappears, and straight lower limb is raised more than 70 °, can recover former work.Take a turn for the better: lumbago and skelalgia alleviates, and the waist movable function improves.Invalid: symptom, sign does not have improvement.
Therapeutic outcome: treat 500 routine patients with lumbar disc herniation: wherein cure 288 examples (accounting for 57.6%), produce effects 116 examples (accounting for 23.2%), effective 52 examples (accounting for 10.4%), invalid 44 examples (accounting for 8.8%), total effective rate reaches 91.2%.
4, the bone strengthening that utilizes the present invention to treat osteopathia increases marrow Chinese patent drugs for treatment fracture patient, has significant curative effect.See following fracture patient treatment clinical data for details.
Utilize the clinical data of Chinese patent drugs for treatment fracture patient of the present invention:
Include fracture patient 1300 examples in, delayed union person 350 examples have wherein been carried out systematic observation.Clavicular fracture 25 examples wherein, humeral fracture 82 examples, chi, radius fracture of both bones 46 examples, fracture of femoral neck 65 examples, fracture of shaft of femur 70 examples, shin, fracture of fibula 51 examples, other 11 example.
Exclusion standard: selected patient all gets rid of other diseases, as merge to have the inclination, serious primary disease persons such as cerebrovascular, liver, kidney and hemopoietic system, to the known composition allergy sufferers of this medicine, the state of an illness is critical, spinal tuberculosis or tumor person and participated in other clinical trial persons in nearly 1 month.
Therapeutic Method: fracture patient is taken the bone strengthening that the present invention treats osteopathia and is increased marrow Chinese patent medicine water preparation, i.e. the bone strengthening that the present invention is made by Radix Ginseng, Radix Rehmanniae, Radix Rehmanniae Preparata, Semen Cuscutae, Herba Epimedii, Fructus Schisandrae Chinensis, Radix Polygoni Multiflori Preparata, Rhizoma Drynariae, Radix Glycyrrhizae, Cornu Cervi Pantotrichum, Radix Bupleuri, the Radix Astragali, Stigma Croci and Mel increases marrow Chinese patent medicine water preparation.Water preparation packing specification is every bottle of 500mL, instructions of taking: each 15ml, every day 3 times, one after each meal.30 days is a course for the treatment of.
The fracture delayed union curative effect determinate standard:
Cure: union of fracture, malformation correction, para-position is good to line, reaches the functional reduction requirement, and local swelling pain disappears, and activity is normal substantially.
Take a turn for the better: fracture approaches healing, and fracture line is fuzzy, and more seriality callus formation is arranged, and para-position is not good enough to line, but near the functional reduction requirement, local swelling pain and movable function improve.
Invalid: fracture is healing not, and symptom and sign are not improved.
Efficacy result to the fracture delayed union patient:
Treat 350 examples: cure 156 examples (accounting for 44.57%), 169 examples that take a turn for the better (accounting for 48.28%), invalid 25 examples (accounting for 7.15%), total effective rate reaches 92.85%.The longest taking medicine 186 days of clinical healing time, the shortest taking medicine 94 days.
The safety analysis result: patient's vital sign comprises blood pressure, heart rate, body temperature and preceding comparison after taking Chinese patent medicine of the present invention, has no significant change, and does not also have the change that clinical meaning is arranged.The result shows to laboratory safety inspection index analysis, and the patient does not all find blood, urine, stool routine examination after taking Chinese patent medicine of the present invention, and liver, renal function and electrocardiogram have the change of clinical meaning.
Model case:
1, Zhang, the woman, 69 years old, went to a doctor in July, 2007.Fall ill year surplus in the of 20, lumbago is obvious.Two lower limb are gone down on one's knees and are got the hip position, two lower limb muscles atrophys.Lumbar vertebra archwise, X sheet show 1-5 lumbar vertebra severe hyperosteogeny, and waist 3-waist 5 intervertebral disk hernia are obviously accompanied lateral bending.Be diagnosed as " prolapse of lumbar intervertebral disc and severe hyperosteogeny ", companion's osteoporosis.Take bone strengthening of the present invention and increase marrow Chinese patent medicine water preparation, prescription is 30 parts of Radix Ginsengs, 30 parts of Radix Rehmanniae, 30 parts of Radix Rehmanniae Preparata, 30 parts of Semen Cuscutae, 20 parts of Herba Epimedii, 30 parts of Fructus Schisandrae Chinensis, 30 parts of Radix Polygoni Multiflori Preparata, 30 parts of Rhizoma Drynariae, 10 parts in Radix Glycyrrhizae, 15 parts in Cornu Cervi Pantotrichum, 30 parts of Radix Bupleuri, 60 parts of the Radixs Astragali, 12 parts of Stigma Crocis and 100 parts of Mel (prescription sees embodiment 1 for details, and the water preparation preparation method sees embodiment 16 for details); Instructions of taking is each 15ml, every day 3 times, one after each meal, 30 days courses for the treatment of.Take Chinese patent drugs for treatment of the present invention and be clearly better after 2 courses for the treatment of, can walk upright, pain relief, the bow-backed alleviation.Continue to take Chinese patent medicine of the present invention transference cure after 2 courses for the treatment of, life can be taken care of oneself, and can participate in productive labor and social activity, recurs so far.
2, Ma, man, 44 years old, Zhouzhuang township, Baofeng County, Henan Province Chen Ying people from village came me institute to go to a doctor patient main suit on March 15th, 2008, waist, the pain that has a pain in the leg, the left lower extremity function is unfavorable more than 2 years, and the patient sprained waist in 2 years in the cause carrying article process accidentally, cause lumbago, emit to left lower extremity then, take a turn for the better through treatment, but outbreak repeatedly, the time heavy when light, be unable to leave the bed when serious, can't take care of oneself, CT examination is done in county people's hospital in the back, is diagnosed as L
4,5Intervertebral disk hernia, heavy when light when being still through repeatedly treating at each county hospital more than 2 years, can't cure.After come my institute to go to a doctor upon somebody's introduction, this outpatient service checks this patient, and in conjunction with the inspection that original hospital does, is diagnosed as " L
4,5Intervertebral disk hernia "; treat subsequently; the hardboard bed crouches in the therapeutic process; waist is fixed; have a rest; take the bone strengthening that the present invention treats osteopathia and increase marrow Chinese patent medicine water preparation, prescription is 29 parts of Radix Ginsengs, 30 parts of Radix Rehmanniae, 29 parts of Radix Rehmanniae Preparata, 30 parts of Semen Cuscutae, 20 parts of Herba Epimedii, 28 parts of Fructus Schisandrae Chinensis, 31 parts of Radix Polygoni Multiflori Preparata, 30 parts of Rhizoma Drynariae, 10 parts in Radix Glycyrrhizae, 15 parts in Cornu Cervi Pantotrichum, 30 parts of Radix Bupleuri, 60 parts of the Radixs Astragali, 12 parts of Stigma Crocis and 100 parts of Mel (prescription sees embodiment 4 for details, and the water preparation preparation method sees embodiment 16 for details); Instructions of taking is each 15ml, every day 3 times, one after each meal, treatment was left hospital after 13 days in the court, and outstanding intervertebral disc recovers firm when leaving hospital, the patient is except waist is stiff, left lower extremity has not had very uncomfortable, can normally walk down, and each joint function recovery is normal, left lower extremity is lifted the lower limb test, CT examination is all normal, and the prolapse of lumbar intervertebral disc thing resets.For consolidate curative effect, leave hospital go home the back patient continue to take 2 courses for the treatment of of Chinese patent medicine of the present invention (30 days is a course for the treatment of), so far the recurrence.
3, Cui, the man, 46 years old, Baofeng County kwan-yin hall village people, this patient is because injuring left lower extremity by a crashing object, cause the tibiofibula two-fold, treat in certain hospital, row left leg open reduction external fixer fixing operation in the therapeutic process, operation back anti-inflammation drugs is treated three wheat harvesting periods, the exercise of still can not leaving the bed, the back film making checks not have any growth of spur.After upon somebody's introduction, on April 8th, 2007, Cui comes me institute to go to a doctor, take the bone strengthening that the present invention treats osteopathia in the therapeutic process and increase marrow Chinese patent medicine water preparation, prescription is 28 parts of Radix Ginsengs, 28 parts of Radix Rehmanniae, 28 parts of Radix Rehmanniae Preparata, 28 parts of Semen Cuscutae, 18 parts of Herba Epimedii, 28 parts of Fructus Schisandrae Chinensis, 28 parts of Radix Polygoni Multiflori Preparata, 28 parts of Rhizoma Drynariae, 8 parts in Radix Glycyrrhizae, 16 parts in Cornu Cervi Pantotrichum, 32 parts of Radix Bupleuri, 58 parts of the Radixs Astragali, 90 parts (prescription sees embodiment 2 for details with Mel for 11 parts of Stigma Crocis, the water preparation preparation method sees embodiment 16 for details), instructions of taking is each 15ml, every day 3 times, one after each meal, take Chinese patent medicine of the present invention after one month, the patient feels that whole body is light, and the exercise of can leaving the bed, continue to take a course for the treatment of (30 days courses for the treatment of), film making checks that fracture line is fuzzy, and existing a large amount of callus bear, do not have very uncomfortable, then take out external fixer, strengthen functional exercise, now work.
4, take charge of certain, the man, 34 years old, Da Ying people from town, Baofeng County, because on the ore deposit, being injured by a crashing object by wood accidentally in the work process, on inspection, right leg causes open fracture, in the wood card impaction fracture, institute treat to me immediately, carry out thorough debridement earlier after being in hospital, manual reduction, plaster fixation, and take anti-inflammatory drug, take the bone strengthening that the present invention treats osteopathia in the therapeutic process simultaneously and increase marrow Chinese patent medicine water preparation, the pharmaceutical formulation of water preparation is 30 parts of Radix Ginsengs, 31 parts of Radix Rehmanniae, 29 parts of Radix Rehmanniae Preparata, 32 parts of Semen Cuscutae, 21 parts of Herba Epimedii, 30 parts of Fructus Schisandrae Chinensis, 30 parts of Radix Polygoni Multiflori Preparata, 30 parts of Rhizoma Drynariae, 10 parts in Radix Glycyrrhizae, 16 parts in Cornu Cervi Pantotrichum, 30 parts of Radix Bupleuri, 60 parts of the Radixs Astragali, 100 parts (pharmaceutical formulation sees embodiment 9 for details with Mel for 13 parts of Stigma Crocis, the water preparation preparation method sees embodiment 16 for details) instructions of taking is each 15ml, every day 3 times, one after each meal is taken the Chinese patent medicine of the present invention inspection of making film after 40 days, and the fracture para-position is good to line, existing a large amount of callus formation, continue to take two courses for the treatment of of Chinese patent medicine of the present invention (30 days courses for the treatment of) subsequently, return to one's perfect health, do not stay any sequela.
5, Zhang, the woman, 62 years old, ore deposit, Dongshan, Westbound, Pingdingshan City family members institute, the patient comes me institute to go to a doctor on March 25th, 2009, it is relatively poor to look into the whole body situation, complexion is cyan darkly, and the sleep diet is poor, drinks gruel and all feels nausea and vomiting, weak all over, soreness of waist and ache in legs, anasarca, each ankylosis of whole body, can not be crooked, have not a particle of motility as robot on foot, can't take care of oneself, in each hospital of city-level, except film making look into bone density relatively poor, each organ of whole body is no abnormal, be diagnosed as " osteoporosis " afterwards my institute ask and examined, take the bone strengthening that the present invention treats osteopathia and increase marrow Chinese patent medicine water preparation, the prescription of Chinese patent medicine water preparation is 29 parts of Radix Ginsengs, 30 parts of Radix Rehmanniae, 29 parts of Radix Rehmanniae Preparata, 30 parts of Semen Cuscutae, 20 parts of Herba Epimedii, 28 parts of Fructus Schisandrae Chinensis, 31 parts of Radix Polygoni Multiflori Preparata, 30 parts of Rhizoma Drynariae, 10 parts in Radix Glycyrrhizae, 15 parts in Cornu Cervi Pantotrichum, 30 parts of Radix Bupleuri, 60 parts of the Radixs Astragali, 12 parts of Stigma Crocis and 100 parts of Mel (prescription sees embodiment 4 for details, and the water preparation preparation method sees embodiment 16 for details); Instructions of taking is each 15ml, and every day 3 times, a day General Symptoms is clearly better surplus in the of 20, and (course for the treatment of 24 Mondays) film making is looked into bone density and recovered normal after the course for the treatment of of taking medicine, and existing patient is fully as healthy people orthobiosis.
6, Liu, woman, 59 years old, Da Ying Zhen Si people from village, Baofeng County, the patient has surplus the rheumatoid arthritis 10 year, often takes Western medicine, comes my institute to go to a doctor through on June 7th, 2007, existing each joint of patient brothers knee joint has begun distortion, pain be can't take care of oneself unbearably, often flu (not good at the various big hospital treatment effect), it is serious that whole body skeleton osteoporosis is looked in film making, directly has influence on patient's physical and mental health.Take the bone strengthening that the present invention treats osteopathia and increase marrow Chinese patent medicine water preparation, the prescription of Chinese patent medicine water preparation is 30 parts of Radix Ginsengs, 30 parts of Radix Rehmanniae, 30 parts of Radix Rehmanniae Preparata, 30 parts of Semen Cuscutae, 20 parts of Herba Epimedii, 30 parts of Fructus Schisandrae Chinensis, 30 parts of Radix Polygoni Multiflori Preparata, 30 parts of Rhizoma Drynariae, 10 parts in Radix Glycyrrhizae, 15 parts in Cornu Cervi Pantotrichum, 30 parts of Radix Bupleuri, 60 parts of the Radixs Astragali, 12 parts of Stigma Crocis and 100 parts of Mel (prescription sees embodiment 1 for details, and the water preparation preparation method sees embodiment 16 for details); Instructions of taking is each 15ml, and every day 3 times, after the course for the treatment of of taking medicine (course for the treatment of 24 Mondays), patient's General Symptoms and pain obviously alleviate, and the patient can take care of oneself fully, and rheumatoid is also obviously controlled.Film making is looked into osteoporosis and is recovered substantially.
Four, the specific embodiment:
Following examples only in order to further specify the present invention, do not limit content of the present invention.
Embodiment 1:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, represent that with weight portion described bone strengthening increases marrow Chinese patent medicine crude drug and consists of 100 parts of 30 parts of Radix Ginsengs, 30 parts of Radix Rehmanniae, 30 parts of Radix Rehmanniae Preparata, 30 parts of Semen Cuscutae, 20 parts of Herba Epimedii, 30 parts of Fructus Schisandrae Chinensis, 30 parts of Radix Polygoni Multiflori Preparata, 30 parts of Rhizoma Drynariae, 10 parts in Radix Glycyrrhizae, 15 parts in Cornu Cervi Pantotrichum, 30 parts of Radix Bupleuri, 60 parts of the Radixs Astragali, 12 parts of Stigma Crocis and Mel.
Embodiment 2:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, represent that with weight portion described bone strengthening increases marrow Chinese patent medicine crude drug and consists of 90 parts of 28 parts of Radix Ginsengs, 28 parts of Radix Rehmanniae, 28 parts of Radix Rehmanniae Preparata, 28 parts of Semen Cuscutae, 18 parts of Herba Epimedii, 28 parts of Fructus Schisandrae Chinensis, 28 parts of Radix Polygoni Multiflori Preparata, 28 parts of Rhizoma Drynariae, 8 parts in Radix Glycyrrhizae, 16 parts in Cornu Cervi Pantotrichum, 32 parts of Radix Bupleuri, 58 parts of the Radixs Astragali, 11 parts of Stigma Crocis and Mel.
Embodiment 3:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, represent that with weight portion described bone strengthening increases marrow Chinese patent medicine crude drug and consists of 110 parts of 32 parts of Radix Ginsengs, 32 parts of Radix Rehmanniae, 32 parts of Radix Rehmanniae Preparata, 32 parts of Semen Cuscutae, 22 parts of Herba Epimedii, 32 parts of Fructus Schisandrae Chinensis, 32 parts of Radix Polygoni Multiflori Preparata, 32 parts of Rhizoma Drynariae, 12 parts in Radix Glycyrrhizae, 14 parts in Cornu Cervi Pantotrichum, 28 parts of Radix Bupleuri, 62 parts of the Radixs Astragali, 13 parts of Stigma Crocis and Mel.
Embodiment 4:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, represent that with weight portion described bone strengthening increases marrow Chinese patent medicine crude drug and consists of 100 parts of 29 parts of Radix Ginsengs, 30 parts of Radix Rehmanniae, 29 parts of Radix Rehmanniae Preparata, 30 parts of Semen Cuscutae, 20 parts of Herba Epimedii, 28 parts of Fructus Schisandrae Chinensis, 31 parts of Radix Polygoni Multiflori Preparata, 30 parts of Rhizoma Drynariae, 10 parts in Radix Glycyrrhizae, 15 parts in Cornu Cervi Pantotrichum, 30 parts of Radix Bupleuri, 60 parts of the Radixs Astragali, 12 parts of Stigma Crocis and Mel.
Embodiment 5:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, represent that with weight portion described bone strengthening increases marrow Chinese patent medicine crude drug and consists of 100 parts of 26 parts of Radix Ginsengs, 29 parts of Radix Rehmanniae, 30 parts of Radix Rehmanniae Preparata, 30 parts of Semen Cuscutae, 18 parts of Herba Epimedii, 32 parts of Fructus Schisandrae Chinensis, 25 parts of Radix Polygoni Multiflori Preparata, 33 parts of Rhizoma Drynariae, 10 parts in Radix Glycyrrhizae, 15 parts in Cornu Cervi Pantotrichum, 33 parts of Radix Bupleuri, 58 parts of the Radixs Astragali, 12 parts of Stigma Crocis and Mel.
Embodiment 6:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, represent that with weight portion described bone strengthening increases marrow Chinese patent medicine crude drug and consists of 105 parts of 33 parts of Radix Ginsengs, 34 parts of Radix Rehmanniae, 27 parts of Radix Rehmanniae Preparata, 26 parts of Semen Cuscutae, 23 parts of Herba Epimedii, 27 parts of Fructus Schisandrae Chinensis, 28 parts of Radix Polygoni Multiflori Preparata, 27 parts of Rhizoma Drynariae, 11 parts in Radix Glycyrrhizae, 17 parts in Cornu Cervi Pantotrichum, 26 parts of Radix Bupleuri, 63 parts of the Radixs Astragali, 14 parts of Stigma Crocis and Mel.
Embodiment 7:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, represent that with weight portion described bone strengthening increases marrow Chinese patent medicine crude drug and consists of 90 parts of 25 parts of Radix Ginsengs, 25 parts of Radix Rehmanniae, 25 parts of Radix Rehmanniae Preparata, 25 parts of Semen Cuscutae, 15 parts of Herba Epimedii, 25 parts of Fructus Schisandrae Chinensis, 25 parts of Radix Polygoni Multiflori Preparata, 25 parts of Rhizoma Drynariae, 8 parts in Radix Glycyrrhizae, 13 parts in Cornu Cervi Pantotrichum, 25 parts of Radix Bupleuri, 55 parts of the Radixs Astragali, 10 parts of Stigma Crocis and Mel.
Embodiment 8:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, represent that with weight portion described bone strengthening increases marrow Chinese patent medicine crude drug and consists of 110 parts of 35 parts of Radix Ginsengs, 35 parts of Radix Rehmanniae, 35 parts of Radix Rehmanniae Preparata, 35 parts of Semen Cuscutae, 25 parts of Herba Epimedii, 35 parts of Fructus Schisandrae Chinensis, 35 parts of Radix Polygoni Multiflori Preparata, 35 parts of Rhizoma Drynariae, 12 parts in Radix Glycyrrhizae, 18 parts in Cornu Cervi Pantotrichum, 35 parts of Radix Bupleuri, 65 parts of the Radixs Astragali, 15 parts of Stigma Crocis and Mel.
Embodiment 9:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, represent that with weight portion described bone strengthening increases marrow Chinese patent medicine crude drug and consists of 100 parts of 30 parts of Radix Ginsengs, 31 parts of Radix Rehmanniae, 29 parts of Radix Rehmanniae Preparata, 32 parts of Semen Cuscutae, 21 parts of Herba Epimedii, 30 parts of Fructus Schisandrae Chinensis, 30 parts of Radix Polygoni Multiflori Preparata, 30 parts of Rhizoma Drynariae, 10 parts in Radix Glycyrrhizae, 16 parts in Cornu Cervi Pantotrichum, 30 parts of Radix Bupleuri, 60 parts of the Radixs Astragali, 13 parts of Stigma Crocis and Mel.
Embodiment 10:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, represent that with weight portion described bone strengthening increases marrow Chinese patent medicine crude drug and consists of 95 parts of 24 parts of Radix Ginsengs, 26 parts of Radix Rehmanniae, 23 parts of Radix Rehmanniae Preparata, 28 parts of Semen Cuscutae, 18 parts of Herba Epimedii, 26 parts of Fructus Schisandrae Chinensis, 28 parts of Radix Polygoni Multiflori Preparata, 30 parts of Rhizoma Drynariae, 8 parts in Radix Glycyrrhizae, 12 parts in Cornu Cervi Pantotrichum, 27 parts of Radix Bupleuri, 54 parts of the Radixs Astragali, 12 parts of Stigma Crocis and Mel.
Embodiment 11:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, represent that with weight portion described bone strengthening increases marrow Chinese patent medicine crude drug and consists of 100 parts of 29 parts of Radix Ginsengs, 30 parts of Radix Rehmanniae, 28 parts of Radix Rehmanniae Preparata, 30 parts of Semen Cuscutae, 20 parts of Herba Epimedii, 30 parts of Fructus Schisandrae Chinensis, 32 parts of Radix Polygoni Multiflori Preparata, 28 parts of Rhizoma Drynariae, 10 parts in Radix Glycyrrhizae, 15 parts in Cornu Cervi Pantotrichum, 30 parts of Radix Bupleuri, 60 parts of the Radixs Astragali, 13 parts of Stigma Crocis and Mel.
Embodiment 12:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, represent that with weight portion described bone strengthening increases marrow Chinese patent medicine crude drug and consists of 110 parts of 32 parts of Radix Ginsengs, 23 parts of Radix Rehmanniae, 32 parts of Radix Rehmanniae Preparata, 24 parts of Semen Cuscutae, 24 parts of Herba Epimedii, 34 parts of Fructus Schisandrae Chinensis, 36 parts of Radix Polygoni Multiflori Preparata, 34 parts of Rhizoma Drynariae, 12 parts in Radix Glycyrrhizae, 18 parts in Cornu Cervi Pantotrichum, 22 parts of Radix Bupleuri, 64 parts of the Radixs Astragali, 10 parts of Stigma Crocis and Mel.
Embodiment 13:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, represent that with weight portion described bone strengthening increases marrow Chinese patent medicine crude drug and consists of 105 parts of 38 parts of Radix Ginsengs, 36 parts of Radix Rehmanniae, 20 parts of Radix Rehmanniae Preparata, 36 parts of Semen Cuscutae, 26 parts of Herba Epimedii, 38 parts of Fructus Schisandrae Chinensis, 24 parts of Radix Polygoni Multiflori Preparata, 38 parts of Rhizoma Drynariae, 5 parts in Radix Glycyrrhizae, 10 parts in Cornu Cervi Pantotrichum, 34 parts of Radix Bupleuri, 58 parts of the Radixs Astragali, 15 parts of Stigma Crocis and Mel.
Embodiment 14:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, represent that with weight portion described bone strengthening increases marrow Chinese patent medicine crude drug and consists of 120 parts of 40 parts of Radix Ginsengs, 20 parts of Radix Rehmanniae, 36 parts of Radix Rehmanniae Preparata, 20 parts of Semen Cuscutae, 30 parts of Herba Epimedii, 40 parts of Fructus Schisandrae Chinensis, 40 parts of Radix Polygoni Multiflori Preparata, 40 parts of Rhizoma Drynariae, 15 parts in Radix Glycyrrhizae, 20 parts in Cornu Cervi Pantotrichum, 40 parts of Radix Bupleuri, 70 parts of the Radixs Astragali, 12 parts of Stigma Crocis and Mel.
Embodiment 15:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, represent that with weight portion described bone strengthening increases marrow Chinese patent medicine crude drug and consists of 100 parts of 20 parts of Radix Ginsengs, 40 parts of Radix Rehmanniae, 40 parts of Radix Rehmanniae Preparata, 40 parts of Semen Cuscutae, 20 parts of Herba Epimedii, 32 parts of Fructus Schisandrae Chinensis, 30 parts of Radix Polygoni Multiflori Preparata, 20 parts of Rhizoma Drynariae, 5 parts in Radix Glycyrrhizae, 12 parts in Cornu Cervi Pantotrichum, 26 parts of Radix Bupleuri, 62 parts of the Radixs Astragali, 12 parts of Stigma Crocis and Mel.
Embodiment 16:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, and described bone strengthening increases marrow Chinese patent medicine crude drug and forms with embodiment 1.
The dosage form that the bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine is water preparation, and the preparation method of water preparation is:
A, the crude drug that increases the marrow Chinese patent medicine according to the bone strengthening of above-mentioned treatment osteopathia are formed proportioning and are taken by weighing various crude drug, at first crude drug Radix Ginseng, Radix Rehmanniae, Radix Rehmanniae Preparata, Semen Cuscutae, Herba Epimedii, Fructus Schisandrae Chinensis, Radix Polygoni Multiflori Preparata, Rhizoma Drynariae, Radix Glycyrrhizae, Cornu Cervi Pantotrichum, Radix Bupleuri, the Radix Astragali and Stigma Croci are placed marmite, the water that adds 6 times of various crude drug gross weights then soaks, and soak time is 12 hours;
B, various crude drug boil it through using after soaking, and change slow fire after boiling into and boil 60 minutes, filter after boiling, and obtain first-time filtrate; Medicine after will filtering then adds the water that accounts for 6 times of medicine gross weights and boils, and changes slow fire after boiling into and boils 60 minutes, carries out the second time and filters, and obtains secondary filtrate after the filtration;
C, the medicine behind the step b secondary filter is added the water account for 6 times of medicine gross weights boil, changing slow fire after boiling into boiled 90 minutes, filter for the third time after boiling, obtain filtrate three times, will be through the filtrate mix homogeneously of three filtrations, the container after the medicinal liquid with mix homogeneously places totally, sterilizes then left standstill 12 hours, left standstill the back and filtered with filter cloth, obtain supernatant, the gained supernatant is boiled aequum with slow fire;
D, step c to be boiled the medicinal liquid that obtains be that the ratio of 1:1 adds Mel according to weight ratio, will add medicinal liquid branch behind the Mel then and pack into and carry out autoclaving in the vial, and sterilization is afterwards stand-by.
Embodiment 17:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, and described bone strengthening increases marrow Chinese patent medicine crude drug and forms with embodiment 2.
The dosage form that the bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine is water preparation, and the preparation method of water preparation is with embodiment 16.
Embodiment 18:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, and described bone strengthening increases marrow Chinese patent medicine crude drug and forms with embodiment 3.
The dosage form that the bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine is water preparation, and the preparation method of water preparation is with embodiment 16.
Embodiment 19:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, and described bone strengthening increases marrow Chinese patent medicine crude drug and forms with embodiment 4.
The dosage form that the bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine is water preparation, and the preparation method of water preparation is with embodiment 16.
Embodiment 20:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, and described bone strengthening increases marrow Chinese patent medicine crude drug and forms with embodiment 5.
The dosage form that the bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine is water preparation, and the preparation method of water preparation is with embodiment 16.
Embodiment 21:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, and described bone strengthening increases marrow Chinese patent medicine crude drug and forms with embodiment 9.
The dosage form that the bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine is water preparation, and the preparation method of water preparation is with embodiment 16.
Embodiment 22:
The bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine, and described bone strengthening increases marrow Chinese patent medicine crude drug and forms with embodiment 11.
The dosage form that the bone strengthening that the present invention treats osteopathia increases the marrow Chinese patent medicine is water preparation, and the preparation method of water preparation is with embodiment 16.
Claims (1)
1. a bone strengthening for the treatment of osteopathia increases the marrow Chinese patent medicine, it is characterized in that: represent that with weight portion described bone strengthening increases the marrow Chinese patent medicine and is made up of for 90～120 parts 20～40 parts of crude drug Radix Ginsengs, 20～40 parts of Radix Rehmanniae, 20～40 parts of Radix Rehmanniae Preparata, 20～40 parts of Semen Cuscutae, 10～30 parts of Herba Epimedii, 20～40 parts of Fructus Schisandrae Chinensis, 20～40 parts of Radix Polygoni Multiflori Preparata, 20～40 parts of Rhizoma Drynariae, 5～15 parts in Radix Glycyrrhizae, 10～20 parts in Cornu Cervi Pantotrichum, 20～40 parts of Radix Bupleuri, 50～70 parts of the Radixs Astragali, 10～15 parts of Stigma Crocis and Mel.
2, the bone strengthening for the treatment of osteopathia according to claim 1 increases the marrow Chinese patent medicine, it is characterized in that: described bone strengthening increases the marrow Chinese patent medicine and is made up of for 90～110 parts 25～35 parts of crude drug Radix Ginsengs, 25～35 parts of Radix Rehmanniae, 25～35 parts of Radix Rehmanniae Preparata, 25～35 parts of Semen Cuscutae, 15～25 parts of Herba Epimedii, 25～35 parts of Fructus Schisandrae Chinensis, 25～35 parts of Radix Polygoni Multiflori Preparata, 25～35 parts of Rhizoma Drynariae, 8～12 parts in Radix Glycyrrhizae, 13～18 parts in Cornu Cervi Pantotrichum, 25～35 parts of Radix Bupleuri, 55～65 parts of the Radixs Astragali, 10～15 parts of Stigma Crocis and Mel.
3, the bone strengthening for the treatment of osteopathia according to claim 1 increases the marrow Chinese patent medicine, it is characterized in that: described bone strengthening increases the marrow Chinese patent medicine and is made up of for 90～110 parts 28～32 parts of crude drug Radix Ginsengs, 28～32 parts of Radix Rehmanniae, 28～32 parts of Radix Rehmanniae Preparata, 28～32 parts of Semen Cuscutae, 18～22 parts of Herba Epimedii, 28～32 parts of Fructus Schisandrae Chinensis, 28～32 parts of Radix Polygoni Multiflori Preparata, 28～32 parts of Rhizoma Drynariae, 8～12 parts in Radix Glycyrrhizae, 14～16 parts in Cornu Cervi Pantotrichum, 28～32 parts of Radix Bupleuri, 58～62 parts of the Radixs Astragali, 11～13 parts of Stigma Crocis and Mel.
4, the bone strengthening according to each described treatment osteopathia of claim 1～3 increases the marrow Chinese patent medicine, it is characterized in that: described Radix Ginseng is the Changbai Mountain Radix Ginseng; Described Fructus Schisandrae Chinensis is the distant five tastes; Described Radix Glycyrrhizae is Radix Glycyrrhizae Preparata.
5, the bone strengthening for the treatment of osteopathia according to claim 1 increases the marrow Chinese patent medicine, it is characterized in that: the dosage form that the bone strengthening of described treatment osteopathia increases the marrow Chinese patent medicine is pharmaceutically acceptable dosage form.
6, a kind of bone strengthening for the treatment of osteopathia increases the marrow Chinese patent medicine, it is characterized in that, the dosage form that the bone strengthening of described treatment osteopathia increases the marrow Chinese patent medicine is water preparation, and the preparation method of water preparation is:
A, the crude drug proportioning that increases the marrow Chinese patent medicine according to the bone strengthening of the described treatment osteopathia of claim 1 take by weighing various crude drug, at first crude drug Radix Ginseng, Radix Rehmanniae, Radix Rehmanniae Preparata, Semen Cuscutae, Herba Epimedii, Fructus Schisandrae Chinensis, Radix Polygoni Multiflori Preparata, Rhizoma Drynariae, Radix Glycyrrhizae, Cornu Cervi Pantotrichum, Radix Bupleuri, the Radix Astragali and Stigma Croci are placed marmite, the water that adds 6～9 times of various crude drug gross weights then soaks, and soak time is 12～16 hours;
B, various crude drug boil it after soaking, and change slow fire after boiling into and boil 50～70 minutes, filter after boiling, and obtain first-time filtrate; Medicine after will filtering then adds the water that accounts for 6～9 times of medicine gross weights and boils, and changes slow fire after boiling into and boils 50～70 minutes, carries out the second time and filters, and obtains secondary filtrate after the filtration;
C, the medicine behind the step b secondary filter is added the water account for 6～9 times of medicine gross weights boil, changing slow fire after boiling into boiled 90～100 minutes, filter for the third time after boiling, obtain filtrate three times, will be through the filtrate mix homogeneously of three filtrations, the container after the medicinal liquid with mix homogeneously places totally, sterilizes then left standstill 12～14 hours, leaving standstill the back filters with filter cloth, obtain supernatant, the gained supernatant is boiled to aequum with slow fire, obtain required medicinal liquid;
D, step c to be boiled the medicinal liquid that obtains be that the ratio of 1:1 adds Mel according to weight ratio, will add medicinal liquid branch behind the Mel then and pack into and carry out autoclaving in the vial, and sterilization is afterwards stand-by.
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| CN105232681A (en) * | 2015-09-25 | 2016-01-13 | 济南邦文医药科技有限公司 | Traditional Chinese medicine composition for treating spleen-stomach deficiency type bone loss around prosthesis after total knee replacement |
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| CN101642524A (en) * | 2009-06-15 | 2010-02-10 | 张继成 | Capsule for kidney and strengthening bones |
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| Title |
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| 温桂荣.鹿茸苁杞汤补肾壮腰骨浅析.《中医药学刊》.2006,第24卷(第7期),1274-1275. |
| 鹿茸苁杞汤补肾壮腰骨浅析;温桂荣;《中医药学刊》;20061231;第24卷(第7期);1274-1275 * |
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