CN102266534B - Medicine for treating insomnia and depression, and preparation method of medicinal pillow inner made of same - Google Patents
Medicine for treating insomnia and depression, and preparation method of medicinal pillow inner made of same Download PDFInfo
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- CN102266534B CN102266534B CN201110260337A CN201110260337A CN102266534B CN 102266534 B CN102266534 B CN 102266534B CN 201110260337 A CN201110260337 A CN 201110260337A CN 201110260337 A CN201110260337 A CN 201110260337A CN 102266534 B CN102266534 B CN 102266534B
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Abstract
The invention discloses a medicine for treating insomnia and depression and a preparation method of a medicinal pillow inner made of the same, and is used for treating insomnia and depression. The invention is characterized in that the medicine for treating insomnia and depression is prepared from the following traditional Chinese medicines in parts by weight: 15 parts of self-heal, 8 parts of radix curcumae, 8 parts of prepared rhizoma cyperi, 8 parts of hemlock parsley, 8 parts of radix sileris, 15 parts of Flos Caryophyllata, 15 parts of flower of silktree, 15 parts of rose, 15 parts of Matrtcaria chamomilla, 8 parts of radix salviae miltiorrhizae, 8 parts of angelica, 8 parts of red paeonia, 8 parts of capillary wormwood and 15 parts of oldenlandia. The preparation method of a medicinal pillow inner made of the medicine for treating insomnia and depression comprises the following steps: extracting radix curcumae, hemlock parsley, radix sileris, radix salviae miltiorrhizae, angelica and red paeonia with water, precipitating with alcohol, concentrating, drying under reduced pressure, pulverizing, mixing with pulverized self-heal, prepared rhizoma cyperi, Flos Caryophyllata, flower of silktree, rose, Matrtcaria chamomilla, capillary wormwood and oldenlandia, and bagging. The clinical experiment proves that the medicine for treating insomnia and depression has the characteristics of favorable curative effect and high safety, and is worthy of clinical application and popularization.
Description
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to a kind of medicine and medicated pillow pillow core method for preparing thereof of Cure for insomnia depression.
Background technology
The insomnia depression is a kind of affective disorder property mental sickness; The incubation period that mainly shows as the sleep of fast quick-action eye phase shortens early awakening and deep sleep reduces; Along with patient age increases, sleep disorder can become more and more serious after midnight, is mostly that mainly the early awakening and the back of waking up are difficult to sleeping again.Patient woke up through midnight two to the three of being everlasting, and filled one's mind with a myriad of thoughts and ideas, and thousand feelings are tangled in grieved condition and do not extricated oneself.The order of severity and the depression order of severity of insomnia have direct relation.When being in a bad way, extremely shorten the length of one's sleep, but have obviously tired meaning daytime, only feels the fatigue and the sense of loss extremely, and this is because arousal level increases, and makes daytime sleeping also difficult.Depression contains the insomnia composition inside, and is to the treatment of this disease, different with general insomnia; Often need pharmaceutical intervention and certain psychotherapy to share, come controlling symptoms through antidepressants and tranquillizing and allaying excitement medicine, the method all has strict regulation to medicine time, quantity and the state of an illness; At will drug withdrawal, otherwise the state of an illness can take place repeatedly, in addition; Such psychotropic drugs side effect is very big, can not effect a radical cure again.Therefore, how to control dosage, reduce the core that drug use becomes the Cure for insomnia depression as much as possible.
Summary of the invention
Technical assignment of the present invention is the deficiency to above prior art, provides a kind of curative effect certainly and the medicine of the little Cure for insomnia depression of side effect.
The technical scheme that the present invention solves its technical problem is: a kind of medicine of Cure for insomnia depression; It is characterized in that being processed into by kinds of traditional Chinese medicines, its weight ratio is: 15 parts of Spica Prunellaes, 8 parts of Radix Curcumaes, 8 parts of Rhizoma Cyperi (processed), 8 parts of Rhizoma Chuanxiongs, windproof 8 parts, 15 parts of Flos Caryophyllis, 15 parts of Flos Albiziaes, 15 parts of Flos Rosae Rugosaes, 15 parts of Flos Matricariae chamomillae, 8 parts of Radix Salviae Miltiorrhizaes, 8 parts of Radix Angelicae Sinensis, 8 parts of Radix Paeoniae Rubra, 8 parts of capillary wormwoods, 15 parts of Herba Hedyotidis Diffusaes.
The method for preparing of the medicine medicated pillow pillow core of above-mentioned a kind of Cure for insomnia depression is made up of following steps:
(1) with Radix Curcumae, Rhizoma Chuanxiong, windproof, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Radix Paeoniae Rubra, water is carried, precipitate with ethanol, concentrate the back drying under reduced pressure, pulverizes;
(2) Spica Prunellae, Rhizoma Cyperi (processed), Flos Caryophylli, Flos Albiziae, Flos Rosae Rugosae, Flos Matricariae chamomillae, capillary wormwood, Herba Hedyotidis Diffusae are pulverized;
(3) step 1 and step 2 gains are mixed, in the medicated bag that the back threading fabric that stirs is processed.
Wherein said: Spica Prunellae is the dry fruit ear of labiate Spica Prunellae Prunella vulgaris L..Nature and flavor are hot, bitter, and are cold.Return liver, gallbladder meridian.Merit can be relieved inflammation or internal heat, and makes eye bright eliminating stagnation, detumescence.
Radix Curcumae is the dried root of zingiberaceous plant RADIX CURCUMAE Curcuma wenyujin Y. H. Chen et C. Ling, Rhizoma Curcumae Longae Curcuma longa L., Guangxi zedoary Curcuma kwangsiensis S. G. Lee et C. F. Liang or Rhizoma Curcumae Curcuma phaeocaulis Val..Nature and flavor are hot, bitter, and are cold.Return liver, the heart, lung meridian.But the merit regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.
Rhizoma Cyperi (processed) is the dry rhizome of sedge dried tuber Cyperus rotundus L., sing the hair must, put the boiling water part omitted boil or steam after dry, or directly dry after burning.Nature and flavor suffering, little hardship, little sweet, flat.Return liver, spleen, tri-jiao channel.But the merit promoting QI circulation for relieving depression, menstruction regulating and pain relieving.
Rhizoma Chuanxiong is the dry rhizome of samphire Rhizoma Chuanxiong Ligusticum chuanxiong Hort. (or Ligusticum wallichii Franch.).Nature and flavor are hot, temperature.Return liver, gallbladder, pericardium channel.But the merit blood-activating and qi-promoting, wind-expelling pain-stopping.
Windproof is the dry root of umbelliferae Saposhnikovia divaricata Saposhnikovia divaricata (Turcz.) Schischk..Nature and flavor are hot, sweet, temperature.Return bladder, liver, spleen channel.But the merit inducing diaphoresis to dispel wind wins and wets, relieving convulsion.
Flos Caryophylli is Myrtaceae syzygium species plant Flos Caryophylli Eugenia caryophyllata Thunb. (E. aromatica Baill.; Syzygium aromatica Merr. et Perry) alabastrum.Nature and flavor are hot, temperature.Return kidney, stomach two warps.But merit warming middle-JIAO, warming the kidney, sending down the abnormal ascending QI.
Flos Albiziae is the dry inflorescence of leguminous plant Herba Albiziae Albizia julibrissin Durazz..Nature and flavor are sweet, and are flat.GUIXIN, Liver Channel.But merit resolving stagnation for tranquilization.
Flos Rosae Rugosae is the dry flower of rosaceous plant Flos Rosae Rugosae Rosa rugosa Thunb..Sweet, the little hardship of nature and flavor, temperature.Return liver, spleen channel.But merit promoting QI circulation for relieving depression, and blood, pain relieving.
Flos Matricariae chamomillae is flower or the herb of feverfew Flos Matricariae chamomillae.Nature and flavor are sweet, and are flat.But the merit wind dispelling induces sweat.
Radix Salviae Miltiorrhizae is the dry root and rhizome of labiate Radix Salviae Miltiorrhizae Salvia miltiorrhiza Bunge..Nature and flavor are bitter, are slightly cold.GUIXIN, Liver Channel.But the merit stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.
When the dry root that is classified as umbelliferae angelica Angelica sinensis (Oliv.) Diels.Nature and flavor are sweet, hot, temperature.Return liver, the heart, spleen channel.Merit can be enriched blood and invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
Radix Paeoniae Rubra is the dry root of ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall. or river Radix Paeoniae Rubra Paeonia veitchii Lynch.Nature and flavor are bitter, are slightly cold.Return Liver Channel.But the merit clearing away heat and cooling blood, eliminating stasis to stop pain.
Capillary wormwood is the dry aerial parts of feverfew BINHAO Artemisia scoparia Waldst. et Kit. or Herba Artemisiae Scopariae Artemisia capillaris Thunb..Nature and flavor are bitter, hot, are slightly cold.Return spleen, stomach, liver, gallbladder meridian.But the merit clearing away damp-heat, the jaundice eliminating subcutaneous ulcer.
Herba Hedyotidis Diffusae is the herb of Rubiaceae cerastium plant Herba Hedyotidis Diffusae Hedyotis diffusa Willd. [Oldenlandia diffusa (Willd.) Roxb.].Nature and flavor are sweet, light, cold.Go into stomach, large intestine, small intestine meridian.But the merit heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain.
Composition principle: the insomnia depression belongs to the category of being insomnia that traditional Chinese medical science damaged by excess of seven emotions causes.Yet people's ortho sleep is the result that the gas of negative and positive transforms certainly regularly; If in a single day this rule is destroyed, just can cause the generation of being insomnia, and the ruined reason of this rule being jammed mainly due to exopathogen such as pry-, gas, blood; The normal operation of gas is defended in interference; Interior traumatic condition will makes the five internal organs movement of QI being out of order, disharmony between QI and blood and imbalance of YIN and YANG and induced insomnia, and mostly pathological factor is gas, blood, expectorant, the stasis of blood, fire, strongly fragrant, wet, food etc., so the insomnia of damaged by excess of seven emotions is particularly important.Zhang Jingyue is said in " Jing Yue's complete work is rolled up 18 and is insomnia ": " sleep this moon of lid, towel its main also Shen Anze sleeps, refreshing uneasiness then is insomnia." and this god ought be meant the mind, i.e. the dominant force person of human physiological activity and mental activity.The heart is the generation part and the dominant force person of human body feelings will.The heart controlling mental and emotional activities, liver master feelings will, spleen will is for thinking, if feelings will is not relaxed excessive thinking; Not only influence the catharsis of liver, stagnation of QI due to depression of the liver occurs, fire-transformation is disturbed god, and further consumes sad blood; Kidney-Yin very unit also can appear exhausting in damage spleen fortune, development at last, and failure of the heart and kindey to integrate mind is not peaceful, and touching difficulty more.The insomnia depression is different from other insomnias and is how sufferer takes antidepressants and tranquillizing and allaying excitement medicine simultaneously, and the method all has strict regulation to medicine time, quantity and the state of an illness, arbitrarily drug withdrawal, and want long-term prescription.
In sum, insomnia depression card genus feelings will is hindered YANG failing to enter YIN of a specified duration.Feelings will is hindered, depression of liver-QI, and the depressed liver-energy dispersing and QI regulating resolving depression, propose in " card is controlled to converge and mended melancholia ": " though strongly fragrant disease is many, all uncomfortable because of gas, it is earlier that method is worked as pleasant." the present invention gets Rhizoma Cyperi (processed) promoting QI circulation for relieving depression, Radix Curcumae heart fire-clearing upset-relieving, Flos Albiziae resolving stagnation for tranquilization, Flos Rosae Rugosae promoting QI circulation for relieving depression; Initial stage hinders at edema caused by disorder of QI, so get windproof inducing diaphoresis to dispel wind, the Flos Matricariae chamomillae wind dispelling induces sweat; Go into blood system for a long time, so get Rhizoma Chuanxiong blood-activating and qi-promoting, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Radix Paeoniae Rubra promoting blood circulation to restore menstrual flow; Strongly fragrant go into for a long time in heat-transformation, so get Spica Prunellae clearing away liver-fire, capillary wormwood clearing away liver-fire, Herba Hedyotidis Diffusae heat-clearing and toxic substances removing; For winter protection medicine of a cold nature thing is impairment of the kidney, so get Flos Caryophylli fragrance warming the kidney, YIN and YANG balance regulating.
The use of medicine of the present invention can be taken orally by decocting, also can be processed into medicine pillow core life-time service.
Ming Dynasty's Li Shizhen (1518-1593 A.D.) has just been put down in writing multiple medicated pillow in Compendium of Material Medica.But the clinical result of use of medicated pillow is not fine, mainly is that traditional medicated pillow is directly pulverized medicine, and in the pillow of packing into, effective ingredient can not be through reaching therapeutic purposes effectively even the rhizome medicine is pulverized the back.Radix Curcumae in the medicine of the present invention, Rhizoma Chuanxiong, windproof, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Radix Paeoniae Rubra extract the back and pulverize and help to absorb, and prescription of the present invention contains fragrance and walk to scurry medicine, are particularly suitable for processing the medicated pillow pillow and use.After using the medicated pillow that medicine of the present invention processes, just can crouch when sleeping rest, body temperature helps drug regimen of the present invention to distribute abnormal smells from the patient and volatile effective component; The patient constantly sucks nasal cavity, trachea and alveolar with its effective ingredient in the rest process; Absorbed by bronchia mucosal, tracheal mucosa and alveolar wall, and get into blood circulation, be input to the histoorgan of body; With stimulating Qi of meridian, dredging the meridian, QI and blood regulating, bring into play its therapeutical effect.
In process of clinical application, medicine decoction oral of the present invention can obviously improve the symptom of insomnia depression.And the medicated pillow pillow that medicine of the present invention is processed, life-time service has no side effect, and improves sleep state effectively, and the medicated pillow pillow was changed once relatively rationally in 2 months.
The specific embodiment
Below in conjunction with practical situation, specific embodiments of the invention elaborates.
Embodiment 1; Spica Prunellae 15g, Radix Curcumae 8g, Rhizoma Cyperi (processed) 8g, Rhizoma Chuanxiong 8g, windproof 8g, Flos Caryophylli 15g, Flos Albiziae 15g, Flos Rosae Rugosae 15g, Flos Matricariae chamomillae 15g, Radix Salviae Miltiorrhizae 8g, Radix Angelicae Sinensis 8g, Radix Paeoniae Rubra 8g, capillary wormwood 8g, Herba Hedyotidis Diffusae 15g; Decoction divides sooner or later and takes for twice.Serve on 30d, clinical observation 42 examples, total effective rate 92%.
Embodiment 2, weight proportion: 15 parts of Spica Prunellaes, 8 parts of Radix Curcumaes, 8 parts of Rhizoma Cyperi (processed), 8 parts of Rhizoma Chuanxiongs, windproof 8 parts, 15 parts of Flos Caryophyllis, 15 parts of Flos Albiziaes, 15 parts of Flos Rosae Rugosaes, 15 parts of Flos Matricariae chamomillae, 8 parts of Radix Salviae Miltiorrhizaes, 8 parts of Radix Angelicae Sinensis, 8 parts of Radix Paeoniae Rubra, 8 parts of capillary wormwoods, 15 parts of Herba Hedyotidis Diffusaes.Method for preparing is made up of following steps: 1. with Radix Curcumae, Rhizoma Chuanxiong, windproof, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Radix Paeoniae Rubra, water is carried, precipitate with ethanol, concentrate the back drying under reduced pressure, pulverizes; 2. Spica Prunellae, Rhizoma Cyperi (processed), Flos Caryophylli, Flos Albiziae, Flos Rosae Rugosae, Flos Matricariae chamomillae, capillary wormwood, Herba Hedyotidis Diffusae are pulverized; 3. step 1 and step 2 gains are mixed, in the medicated bag that the back threading fabric that stirs is processed.Each medicated bag content weight 150g places on the medicated pillow, covers pillow covering towel or pillowcase outward.Changed once in per 2 months, clinical 56 routine patients used 1 year, did not see untoward reaction, total effective rate 83%.
Claims (2)
1. the medicine of a Cure for insomnia depression; It is characterized in that being processed into by kinds of traditional Chinese medicines, its weight ratio is: 15 parts of Spica Prunellaes, 8 parts of Radix Curcumaes, 8 parts of Rhizoma Cyperi (processed), 8 parts of Rhizoma Chuanxiongs, windproof 8 parts, 15 parts of Flos Caryophyllis, 15 parts of Flos Albiziaes, 15 parts of Flos Rosae Rugosaes, 15 parts of Flos Matricariae chamomillae, 8 parts of Radix Salviae Miltiorrhizaes, 8 parts of Radix Angelicae Sinensis, 8 parts of Radix Paeoniae Rubra, 8 parts of capillary wormwoods, 15 parts of Herba Hedyotidis Diffusaes.
2. the method for preparing of the medicine medicated pillow pillow core of a kind of Cure for insomnia depression as claimed in claim 1, form by following steps:
(1) with Radix Curcumae, Rhizoma Chuanxiong, windproof, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Radix Paeoniae Rubra, water is carried, precipitate with ethanol, concentrate the back drying under reduced pressure, pulverizes;
(2) Spica Prunellae, Rhizoma Cyperi (processed), Flos Caryophylli, Flos Albiziae, Flos Rosae Rugosae, Flos Matricariae chamomillae, capillary wormwood, Herba Hedyotidis Diffusae are pulverized;
(3) step 1 and step 2 gains are mixed, in the medicated bag that the back threading fabric that stirs is processed.
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CN105079424A (en) * | 2015-08-31 | 2015-11-25 | 南京正宽医药科技有限公司 | Pharmaceutical preparation for treating sleeplessness |
CN106310140A (en) * | 2016-10-30 | 2017-01-11 | 周振勇 | Drug for treating postnatal depression |
CN112089782B (en) * | 2020-09-22 | 2021-11-23 | 上海市静安区中医医院 | Traditional Chinese medicine pillow capable of relieving depression and application thereof |
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畅洪升.《四逆散抗抑郁作用的理论与实验研究》.《北京中医药大学博士研究生学位论文》.2003,正文. * |
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