CN102266411A - Chinese medicinal formula for treating lupus erythematosus - Google Patents
Chinese medicinal formula for treating lupus erythematosus Download PDFInfo
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- CN102266411A CN102266411A CN2011102346138A CN201110234613A CN102266411A CN 102266411 A CN102266411 A CN 102266411A CN 2011102346138 A CN2011102346138 A CN 2011102346138A CN 201110234613 A CN201110234613 A CN 201110234613A CN 102266411 A CN102266411 A CN 102266411A
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Abstract
The invention provides a Chinese medicinal formula for treating lupus erythematosus. The formula comprises, by weight, 25 to 35 parts of rhizoma atractylodis, 10 to 20 parts of cortex dictamni, 10 to 20 parts of charred Radix et Rhizome Rhei, 7 to 15 parts of flos rosae rugosae, 7 to 15 parts of red sage root, 8 to 16 parts of leech, 8 to 16 parts of Radix Astragali and 10 to 20 parts of sweet wormwood. The Chinese medicinal formula for treating lupus erythematosus provided in the invention has good effects, enables a low recurrence rate, realizes simultaneous treatment of principal and subordinate symptoms of lupus erythematosus, and effectively relieves sufferings of patients.
Description
Technical field
The present invention relates to a kind of Chinese medicine, more particularly, relate to a kind of Chinese medicine preparation for the treatment of lupus erythematosus.
Background technology
Lupus erythematosus is a kind of many organs of health multisystem that involve, complicated clinical manifestation, course of disease delay autoimmune disease repeatedly.
The pathogenesis of lupus erythematosus is not illustrated as yet fully, studies show that in a large number primary disease is a kind of autoimmune disease, can involve health multisystem, many organs, can find multiple autoantibody in patient's blood and organ.Some have the lupus erythematosus patient of inherited genetic factors, under some external world or the effect of inside of human body factor, inspired an immunne response as viral infection, sunlight exposure, psychic trauma, medicine, gestation etc., thereby produce multiple antibody and the immune complex of resisting autologous tissue, cause the human body self tissue, as organ and tissues such as skin, blood vessel, the heart, liver, kidney, brains, malpractice is outbreak repeatedly easily, and each recurrence all might increase the weight of the state of an illness.The western medical treatment lupus erythematosus adopts hormone more, can't stablize control.Therapeutic effect is not obvious, and it is slow to take effect.Owing to can not get effective alleviation, lupus erythematosus patient stands skin lesion for a long time, arthropathy, and heart, respiratory system also can suffer damage.Clinical characteristics still can be involved vitals such as the heart, kidney simultaneously except that skin lesion is arranged, often with General Symptomies such as heating, joint aches.
Summary of the invention
Problem in view of above-mentioned prior art exists the purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of lupus erythematosus, and it is at the comprehensive cause of disease of lupus erythematosus, determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, and it is effective, relapse rate is low, treating both the principal and secondary aspects of a disease, has effectively removed patient's slight illness.
In order to address the above problem, the present invention is by the following technical solutions: a kind of Chinese medicine preparation for the treatment of lupus erythematosus, in weight portion, comprise following component: Rhizoma Atractylodis 25-35, Cortex Dictamni 10-20, charred Radix Et Rhizoma Rhei 10-20, Flos Rosae Rugosae 7-15, Flos Campsis 7-15, Radix Salviae Miltiorrhizae 7-15, Hirudo 8-16, Radix Astragali 8-16, Herba Artemisiae Annuae 10-20.
The Analysis on Mechanism of Chinese medicine of the present invention:
Rhizoma Atractylodis: hot, bitter, temperature.Return spleen, stomach, Liver Channel.Drying damp and strengthening spleen, expelling wind and cold makes eye bright.Compendium of Material Medica: control the damp-phlegm prolonged fluid-retention, or hold blood stasis under the arm and become the nest capsule, and spleen is wet dirty, turbid drop leukorrhagia, the sliding hemorrhoidal hamorrhage that rushes down.
Cortex Dictamni: hardship; Salty; Cold.Return spleen channel; Lung meridian; Small intestine meridian; The stomach warp; Urinary bladder channel.Heat clearing and damp drying; Dispelling wind for relieving itching; Detoxifcation." book on Chinese herbal medicine is original ": Cortex Dictamni, go into lung meridian, so can remove wind, go into small intestine meridian, so can dry, husband's rheumatism was both removed, then also go by heat from living for vim and vigour.Control all mange, aversion to wind, scabies, Fructus Myricae rubrae, all skin ulcer pyretic toxicity.
Charred Radix Et Rhizoma Rhei: hardship, cold.Return spleen, stomach, large intestine, liver, pericardium channel.Cooling blood and removing stasis, hemostasis." Japan hanako materia medica ": logical all gas of a surname, blood circulation regulating, sharp joint is let out and is moulded stagnant, aqueous vapor, the extremity unbalanced cold and heat, warm miasma heat-phlegm, sharp defecation, and apply-Qie furuncle carbuncle poison.
Flos Rosae Rugosae: sweet, little hardship, temperature.Return liver, spleen channel.Promoting QI circulation for relieving depression, and blood, pain relieving." book on Chinese herbal medicine justice ": Flos Rosae Rugosae, fragrance is the denseest, turbid clearly and not and and not violent, the easing the affected liver stomach of waking up, gas is invigorated blood circulation, a surname is logical to stop up and stagnates and do not have a hot temperature dry fraud just extremely, disconnectedly push away among the edema caused by disorder of QI medicine, prompt effect arranged and the most tractable person most, fragrant all product, there is no equal.
Flos Campsis: sweet, sour, cold.Return liver, pericardium channel.The promoting the circulation of blood blood stasis removing, cooling blood, expelling wind." Amplification on Materia Medica addendum ": Flos Campsis, the key medicine of controlling pain in the blood also, and the nourishing YIN victory is very, is stamped to keep and walk alone, and is many with what in the married woman side.
Radix Salviae Miltiorrhizae: hardship is slightly cold.GUIXIN, Liver Channel.Promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind." detailed outline ": invigorate blood circulation logical percardium.Control colic.
Hirudo: salty hardship is flat, and is poisonous.Return Liver Channel.Removing blood stasis; Tong Jing Xiao Disorder." herbal classic ": main by closing stagnant blood, blood stasis, the moon, the removing blood stasis abdominal mass is gathered, the loss of fecundity dredging water passages.
The Radix Astragali: sweet, tepor.Return lung, spleen, liver, kidney channel.The invigorating middle warmer of Radix Astragali Preparata QI invigorating is given birth to consolidating superficial resistance holder skin ulcer." the herbal speech that converges ":,,, control impairment caused by overstrain, longue meat so energy complement sun fills space between skin and muscles so specially reach table in edema caused by disorder of QI because of its flavor is light.The deficiency of vital energy and difficult antiperspirant person can send out, table is dredged and hyperhidrosis person can end.
Herba Artemisiae Annuae: bitter in the mouth; Little suffering; Cold in nature.Return liver; Gallbladder meridian.Heat clearing away; Expelling summer-heat; Remove and steam; Preventing the attack (or recurrence) of malaria.Shennong's Herbal: main scabies scabies crust is itched, and malignant boil kills louse, stays heat between joint, makes eye bright.
According to the Chinese medicine preparation of treatment lupus erythematosus of the present invention, in the principle of adjusting, balance internal organs, follow the principle of blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing within its integrated use traditional Chinese medical science, determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, mutual reinforcement between are usefulness, the dampness blood stasis dispelling.Cortex Dictamni dispeiling pathogenic wind and removing dampness in the side; Rhizoma Atractylodis are drying damp and strengthening spleen; The Radix Et Rhizoma Rhei blood stasis removing and clots absorbing; The Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling; Flos Campsis, Flos Rosae Rugosae cooling blood and removing stasis; Hirudo removing blood stasis, stasis of blood person's pathogenic factor also, heresy goes to see Zhengan County, the stasis of blood then newborn ruton of dispelling; Radix Astragali strengthening the body resistance, the immunoregulation effect that tool is two-way; The Herba Artemisiae Annuae clearing heat and expelling damp, antagonist forms cell inhibitory action, and the pair cell immunity has facilitation.All medicines are played strengthening vital QI to eliminate pathogenic factors altogether, the merit of dispeiling pathogenic wind and removing dampness, blood circulation promoting and blood stasis dispelling, YIN and YANG balance regulating.The treatment lupus erythematosus, effect is remarkable, double taking stopgap measures originally.
Chinese medicine preparation of the present invention can adopt dosage forms such as tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder, preferably, can adopt solution, tablet, granule and capsule.
Result of use
The treatment group: select experimenter's 20 examples, 10 routine male wherein, 10 routine women, age 30-40 year, take Chinese patent medicine of the present invention twice sooner or later, continue 1 month.
Matched group: select experimenter's 20 examples, 10 routine male wherein, 10 routine women, age 30-40 year, treat with glucocorticoid, continue 1 month.
Judgment criteria:
1. cure: low grade fever disappears, and skin lesion is alleviated, disappeared; Arthralgia obviously alleviates, and focus alleviates, heart, renal system remission;
2. effective: low grade fever, skin lesion goes down, and arthralgia alleviates;
3. invalid: no change, symptom does not have mitigation.
Continued treatment is after 2 courses of treatment, and the result shows, healing number 9 people in the treatment group; Effective number 9 people; Invalid number 2 people, overall effective percentage reaches 90%.And healing number 10 people in the matched group; Effective number 7 people; Invalid number 3 people; Overall effective percentage is 85%, but there is the risk that causes side effect such as steroid diabetes and Cushing's syndrome in matched group.
The specific embodiment
In order to understand the present invention better, the present invention is described below by embodiment.
Embodiment 1
A kind of Chinese medicine preparation for the treatment of lupus erythematosus in weight portion, comprises following component: Rhizoma Atractylodis 25, Cortex Dictamni 10, charred Radix Et Rhizoma Rhei 10, Flos Rosae Rugosae 7, Flos Campsis 7, Radix Salviae Miltiorrhizae 7, Hirudo 8, the Radix Astragali 8, Herba Artemisiae Annuae 10.
Its preparation method is:
In weight portion, get Rhizoma Atractylodis 25, Cortex Dictamni 10, charred Radix Et Rhizoma Rhei 10, Flos Rosae Rugosae 7, Flos Campsis 7, Radix Salviae Miltiorrhizae 7, Hirudo 8, the Radix Astragali 8, Herba Artemisiae Annuae 10;
Above-mentioned Chinese medicine is cleaned, and decontamination is put into container and is added water and do not have medical material to soak, and after 30 minutes, big fire decocts to boiling, and slow fire was endured 1 hour slowly then;
Medicine juice is leached, bag distribution packaging, one bag of 200ml sooner or later respectively obeys one bag, and the dual-purpose medicinal liquid cleans affected part, and 1 month is a course of treatment.
Embodiment 2
A kind of Chinese medicine preparation for the treatment of lupus erythematosus in weight portion, comprises following component: Rhizoma Atractylodis 35, Cortex Dictamni 20, charred Radix Et Rhizoma Rhei 20, Flos Rosae Rugosae 15, Flos Campsis 15, Radix Salviae Miltiorrhizae 15, Hirudo 16, the Radix Astragali 16, Herba Artemisiae Annuae 20.
Its preparation method is:
In weight portion, get Rhizoma Atractylodis 35, Cortex Dictamni 20, charred Radix Et Rhizoma Rhei 20, Flos Rosae Rugosae 15, Flos Campsis 15, Radix Salviae Miltiorrhizae 15, Hirudo 16, the Radix Astragali 16, Herba Artemisiae Annuae 20; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; The packing of granule racking machine promptly gets granule.
Embodiment 3
A kind of Chinese medicine preparation for the treatment of lupus erythematosus in weight portion, comprises following component: Rhizoma Atractylodis 30, Cortex Dictamni 15, charred Radix Et Rhizoma Rhei 15, Flos Rosae Rugosae 10, Flos Campsis 10, Radix Salviae Miltiorrhizae 10, Hirudo 12, the Radix Astragali 12, Herba Artemisiae Annuae 15.
Its preparation method is:
In weight portion, get Rhizoma Atractylodis 30, Cortex Dictamni 15, charred Radix Et Rhizoma Rhei 15, Flos Rosae Rugosae 10, Flos Campsis 10, Radix Salviae Miltiorrhizae 10, Hirudo 12, the Radix Astragali 12, Herba Artemisiae Annuae 15; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; Add suitable adjuvant magnesium stearate, the tablet machine tabletting, coating promptly gets tablet.
Embodiment 4
A kind of Chinese medicine preparation for the treatment of lupus erythematosus in weight portion, comprises following component: Rhizoma Atractylodis 30, Cortex Dictamni 15, charred Radix Et Rhizoma Rhei 15, Flos Rosae Rugosae 10, Flos Campsis 10, Radix Salviae Miltiorrhizae 10, Hirudo 12, the Radix Astragali 12, Herba Artemisiae Annuae 15.
Its preparation method is:
In weight portion, get Rhizoma Atractylodis 30, Cortex Dictamni 15, charred Radix Et Rhizoma Rhei 15, Flos Rosae Rugosae 10, Flos Campsis 10, Radix Salviae Miltiorrhizae 10, Hirudo 12, the Radix Astragali 12, Herba Artemisiae Annuae 15; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; Granule is made the 0.4g/ capsules with the capsule filler.
Claims (4)
1. Chinese medicine preparation for the treatment of lupus erythematosus, it is characterized in that, in weight portion, comprise following component: Rhizoma Atractylodis 25-35, Cortex Dictamni 10-20, charred Radix Et Rhizoma Rhei 10-20, Flos Rosae Rugosae 7-15, Flos Campsis 7-15, Radix Salviae Miltiorrhizae 7-15, Hirudo 8-16, Radix Astragali 8-16, Herba Artemisiae Annuae 10-20.
2. Chinese medicine preparation according to claim 1 is characterized in that, in weight portion, preferably comprises following component: Rhizoma Atractylodis 30, Cortex Dictamni 15, charred Radix Et Rhizoma Rhei 15, Flos Rosae Rugosae 10, Flos Campsis 10, Radix Salviae Miltiorrhizae 10, Hirudo 12, the Radix Astragali 12, Herba Artemisiae Annuae 15.
3. Chinese medicine preparation according to claim 1 and 2 is characterized in that, described Chinese medicine preparation adopts tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.
4. Chinese medicine preparation according to claim 3 is characterized in that, described Chinese medicine preparation adopts solution, tablet, granule and capsule.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103751348A (en) * | 2014-01-03 | 2014-04-30 | 铜陵桂生生态养殖有限公司 | Composition for treating meridian-collateral blockage type lupus erythematosus |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103751348A (en) * | 2014-01-03 | 2014-04-30 | 铜陵桂生生态养殖有限公司 | Composition for treating meridian-collateral blockage type lupus erythematosus |
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Application publication date: 20111207 |