CN102266404A - Traditional Chinese medicine for treating rheumatoid arthritis - Google Patents
Traditional Chinese medicine for treating rheumatoid arthritis Download PDFInfo
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- CN102266404A CN102266404A CN2011102328375A CN201110232837A CN102266404A CN 102266404 A CN102266404 A CN 102266404A CN 2011102328375 A CN2011102328375 A CN 2011102328375A CN 201110232837 A CN201110232837 A CN 201110232837A CN 102266404 A CN102266404 A CN 102266404A
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Abstract
The invention provides a traditional Chinese medicine for treating rheumatoid arthritis. The traditional Chinese medicine is characterized by comprising the following components in parts by weight: 10-14 parts of processed common monkshood mother root, 8-12 parts of Chinese ephedra, 35-45 parts of astragalus root, 10-14 parts of cassia twig, 6-10 parts of wild ginger, 10-14 parts of peach kernel, 12-18 parts of red paeony root, 12-18 parts of twotooth achyranthes root, 25-35 parts of wooly datchmanspipe herb, 25-35 parts of garter snake, 4-8 parts of liquoric root and 0.5-1.5 parts of centipede meal. A Chinese medicinal formula disclosed by the invention has the effects of dispersing pathogenic wind, eliminating stagnation, stimulating the menstrual flow, promoting the circulation of qi, promoting blood circulation, removing blood stasis, dissipating blood stasis and diminishing swelling. In the traditional Chinese medicine, a plurality of Chinese medicinal ingredients complement one another, so that circulatory disturbance is dredged and damaged joints are recovered. The internal secretion of a mechanism is regulated, and internal hormonal balance is maintained. The traditional Chinese medicine has a remarkable treatment effect, and does not have any toxic or side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine, more particularly, relate to a kind of Chinese medicine for the treatment of rheumatoid arthritis.
Background technology
Rheumatoid arthritis (rheumatoid arthritis) be a kind of be the chronic systemic autoimmune disease of feature with the articular synovitis.Synovitis is outbreak repeatedly lastingly, the destruction that can cause intraarticular cartilage and bone, and joint function disturbance, in addition maimed.The vasculitis pathological changes is involved each organ of whole body, so primary disease is called rheumatoid disease again.
Rheumatoid arthritis claims rheumatoid (RA) again, is the chronic systemic inflammatory disease that a kind of cause of disease is not understood as yet, is main clinical manifestation with pathological changes outside chronic, symmetry, many synovial jointss inflammation and the joint, belongs to the autoimmune inflammatory diseases.This disease is sent out well in little joints such as hands, wrist, foots, and outbreak is symmetrical distribution repeatedly.Joint red and swollen heat pain and dysfunction are arranged in early days, and late period, stiff deformity in various degree can appear in the joint, and with bone and skeletal muscle atrophy, very easily disabled.From the angle of pathological change, rheumatoid arthritis is a kind of synovium of joint (can feed through to articular cartilage, osseous tissue, articular ligament and flesh key later on) that mainly involves, and is the popularity diseases associated with inflammation of connective tissues such as serous coat, the heart, lung and eye secondly.The general performance of rheumatoid arthritis also has heating, fatigue and weak, pericarditis, subcutaneous nodule, pleuritis, arteritis, peripheral neuropathy etc. except that arthropathy.Its cause of disease is clear and definite fully as yet, and rheumatoid arthritis is one and the closely-related diseases of factor such as environment, cell, virus, heredity, gonadal hormone and the neural mental status.Therapeutic strategy to rheumatoid arthritis mainly adopts at present: 1. control the inflammation of joint and other tissue, relief of symptoms; 2. keep function of joint and prevent deformity; 3. repair impaired joint to ease the pain and restore funcitons.These methods have the effect of alleviation to disease, prevent its further deterioration, but can not thoroughly cure, disease is not significantly repaired yet, and often with toxic and side effects.
Summary of the invention
Problem in view of above-mentioned prior art exists the purpose of this invention is to provide a kind of Chinese medicine for the treatment of rheumatoid arthritis, and it is treated simultaneously at the external pathogenic factor of arthritis, inherent body void, to obtain the effect for the treatment of both the principal and secondary aspects of a disease.
In order to address the above problem, the present invention is by the following technical solutions: a kind of Chinese medicine for the treatment of rheumatoid arthritis, in weight portion, comprise following component: Radix Aconiti Preparata 10-14, Herba Ephedrae 8-12, Radix Astragali 35-45, Ramulus Cinnamomi 10-14, Herba Asari 6-10, Semen Persicae 10-14, Radix Paeoniae Rubra 12-18, Radix Achyranthis Bidentatae 12-18, Herba Aristolochiae Mollissimae 25-35, Ophidia black snake powder 25-35, Radix Glycyrrhizae 4-8 and Scolopendra powder 0.5-1.5.
The drug action mechanism of Chinese medicine of the present invention is as follows:
Radix Aconiti Preparata: hot, bitter, heat; Poisonous.GUIXIN, liver,kidney,spleen warp.Expelling wind and removing dampness, antalgic.Be used for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.The Radix Aconiti total alkali can significantly suppress the foot swelling that rat carrageenan, bright egg soup, histamine and 5-hydroxy tryptamine cause.
Herba Ephedrae: hot, little hardship, temperature.Return lung, urinary bladder channel.It is strong to give birth to product relieving the exterior syndrome by diaphoresis and inducing diuresis to remove edema power, is used for chill exterior syndrome, uncomfortable in chest breathing with cough, edema due to wind pathogen edema, rheumatic arthralgia more." herbal classic " note: " main apoplexy, cold headache, pyrexial malaria.Deliver perspiration, the steam that uncharms ends cough with dyspnea, removes cold and heat, and broken heavily fortified point gathers.”
The Radix Astragali: sweet, tepor.Return lung, spleen, liver, kidney channel.There are benefiting QI for strengthening the superficies, arresting sweating to take off, hold in the palm the effect of skin ulcer granulation promoting, inducing diuresis to remove edema admittedly.
Ramulus Cinnamomi: hot, sweet, temperature.GUIXIN, lung, urinary bladder channel.The diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.Be used for anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia." book on Chinese herbal medicine converge with speech " note: " Ramulus Cinnamomi, dispersing wind and cold by pathogenic factor in the exterior, send out antiperspirant evil, and cough-relieving is coughed, and the medicine that goes wind pain between podomere also.Though from hot, body does not belong to branch to abnormal smells from the patient, only can disperse between the fur flesh natural fibre line of meat parade arm knee joint podomere part.”
Herba Asari: acrid in the mouth, temperature.Go into the heart, liver, gallbladder, spleen four warps.Has expelling wind and cold, understand things pain-stopping, the effect of warming the lung to resolve fluid-retention." herbal classic " note: " main cough with dyspnea, the headache brain is moving, hundred joint contractures, rheumatic arthralgia, dead flesh.Make eye bright sharp nine orifices." Herba Asari has certain inhibitory action to rat formaldehyde and Ovum Gallus domesticus album swelling of the feet. Oleum Asari has tangible antiinflammatory action, can significantly suppress yeast, formaldehyde-caused rat arthroncus.4 kinds of compositions such as contained methyleugenol, Kakuol, N-isobutyl group 12 carbon tetraene amide and demethylcoclaurine have antihistamine effect in the water-insoluble separating part of Herba Asari methanol leachate.
Semen Persicae: bitter, sweet, flat.GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.Be used for amenorrhea, dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down.Zoopery proves that Semen Persicae has the inflammation of promotion Absorption, to the inflammation initial stage, stronger exudation effect is arranged.
Radix Paeoniae Rubra: hardship is slightly cold.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.Be used for maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, injury from falling down, carbuncle skin infection.
Radix Achyranthis Bidentatae: hardship, acid, property is flat.Return liver, kidney channel.Cure mainly soreness of waist and knee joint, flaccidity and weakness of the lower limbs, amenorrhea due to stagnation of blood.. " herbal classic " note: " gonalgia can not be bent for main cold-damp flaccidity syndrome and arthralgia syndrome, spasm of the limbs, and by vim and vigour, the fire of getting mildewed in warm conditions is mashed, induced abortion.”
Herba Aristolochiae Mollissimae: bitter in the mouth is flat.Return Liver Channel.Wind-damp dispelling, the meridian dredging, pain relieving.Be used for rheumatic arthralgia, numb limbs and tense tendons, muscles and bones contracture, traumatic injury pain." Nanjing medicinal herbs among the people ": " herb infusing drugs in wine clothes are controlled bones and muscles pain and belly pain.”
Zaocys: sweet, flat.Return Liver Channel.Dispel the wind collateral dredging, relieving convulsion.Be used for rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.
Radix Glycyrrhizae: property is flat, and sweet in the mouth is returned 12 warps.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
The Scolopendra powder: salty, hot, temperature.Poisonous.Return liver, spleen, lung meridian.Relieve internal heat, relieving spasm by calming endogenous wind, move back scorching pain relieving, eliminating stagnation.
Chinese medicine according to treatment rheumatoid arthritis of the present invention, within its integrated use traditional Chinese medical science regulate, the principle of balance internal organs, follow the principle of expelling wind and removing dampness, dispersing cold for relieving pain, adopt Radix Aconiti Preparata, Herba Ephedrae, Herba Asari, Herba Aristolochiae Mollissimae, Ophidia black snake powder as principal agent, eliminate dampness, hydrops and swelling, the red and swollen heat pain that heresy causes in the treatment, the scorchingly hot caused scorchingly hot numbness of heresy of its diseases caused by exogenous pathogenic factor of loosing is again led to, the merit of pain relieving, wind-damp dispelling the meridian dredging promoting the circulation of QI to induce diuresis is arranged, cure mainly arthralgia; In conjunction with selecting for use the Radix Astragali, Ramulus Cinnamomi, Semen Persicae, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae as ministerial drug, tonifying QI and activating blood circulation to eliminate blood stasis, clearing away heat and cooling blood, dissipating blood stasis for subsidence of swelling with the merit of auxilliary monarch drug dispelling wind and removing obstruction in the collateral, are dredged circulatory disturbance; Assistant is with Radix Glycyrrhizae and middle emergency coordinating the actions of various ingredients in a prescription; Adopt Scolopendra powder expelling wind to relieve convulsion, pain relieving counteracting toxic substances simultaneously, pick the power that penetrates, draw all medicines with the persistent ailment of dispelling to search.
Chinese medicine preparation of the present invention can adopt dosage forms such as tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder, preferably, can adopt solution, tablet, granule and pill.
Result of use:
The treatment group: select experimenter's 60 examples, 25 routine male wherein, 25 routine women, age 15-30 year, take Chinese medicine composition of the present invention twice sooner or later, continue 1 month.
Matched group: select experimenter's 60 examples, 25 routine male wherein, 25 routine women, age 15-30 year, with methotrexate, Radix Tripterygii Wilfordii, treat, continue 1 month.
Judgment criteria: arthralgia disappears, and swelling is disappeared, and no morning is stiff for curing; Arthralgia obviously alleviates, and swelling reduces, and no morning, deadlock was effective; Symptom does not have mitigation, and swelling does not have and disappears or have morning stiff for invalid.
Continued treatment is after 1 course of treatment, and the result shows, healing number 38 people in the treatment group; Effective number 18 people; Invalid number 4 people, overall effective percentage reaches 93.3%.And healing number 18 people in the matched group; Effective number 30 people; Invalid number 12 people; Overall effective percentage is 80%, and side effect such as matched group anorexia occurs, feels sick, vomiting, stomatitis, alopecia.
Chinese medicine preparation of the present invention has dispelling wind-evil and transforming calculus concurrently, the effect of the circulation of qi promoting of stimulating the menstrual flow, blood circulation promoting and blood stasis dispelling, dissipating blood stasis for subsidence of swelling, and the plurality of Chinese composition complements each other, and mediation circulatory disturbance is repaired impaired joint.Regulate organism endocrine, keep the hormone in vivo balance.Therapeutic effect is remarkable, has no side effect.
The specific embodiment
In order to understand the present invention better, the present invention is described below by embodiment.
Embodiment 1
A kind of Chinese medicine for the treatment of rheumatoid arthritis in weight portion, comprises following component: Radix Aconiti Preparata 10, Herba Ephedrae 8, the Radix Astragali 35, Ramulus Cinnamomi 10, Herba Asari 6, Semen Persicae 10, Radix Paeoniae Rubra 12, Radix Achyranthis Bidentatae 12, Herba Aristolochiae Mollissimae 25, Ophidia black snake powder 25, Radix Glycyrrhizae 4 and Scolopendra powder 0.5.
Its preparation method is:
Get Radix Aconiti Preparata 10, Herba Ephedrae 8, the Radix Astragali 35, Ramulus Cinnamomi 10, Herba Asari 6, Semen Persicae 10, Radix Paeoniae Rubra 12, Radix Achyranthis Bidentatae 12, Herba Aristolochiae Mollissimae 25, Zaocys 25, Radix Glycyrrhizae 4 and Scolopendra powder 0.5;
Above-mentioned Chinese medicine is cleaned, and decontamination is put into container and is added water and do not have medical material to soak, and after 30 minutes, big fire decocts to boiling, and slow fire was endured 1 hour slowly then;
Medicine juice is leached, bag distribution packaging, one bag of 200ml sooner or later respectively obeys one bag, and the dual-purpose medicinal liquid cleans affected part, and 1 month is a course of treatment.
Embodiment 2
A kind of Chinese medicine for the treatment of rheumatoid arthritis, in weight portion, comprise following component: Radix Aconiti Preparata 14, Herba Ephedrae 12, the Radix Astragali 45, Ramulus Cinnamomi 14, Herba Asari 10, Semen Persicae 14, Radix Paeoniae Rubra 18, Radix Achyranthis Bidentatae 18, Herba Aristolochiae Mollissimae 35, Ophidia black snake powder 35, Radix Glycyrrhizae 8 and Scolopendra powder 1.5.
Its preparation method is:
Get Radix Aconiti Preparata 14, Herba Ephedrae 12, the Radix Astragali 45, Ramulus Cinnamomi 14, Herba Asari 10, Semen Persicae 14, Radix Paeoniae Rubra 18, Radix Achyranthis Bidentatae 18, Herba Aristolochiae Mollissimae 35, Zaocys 35, Radix Glycyrrhizae 8 and Scolopendra powder 1.5;
Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour;
Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; The packing of granule racking machine promptly gets granule.
Embodiment 3
A kind of Chinese medicine for the treatment of rheumatoid arthritis in weight portion, comprises following component: Radix Aconiti Preparata 12, Herba Ephedrae 10, the Radix Astragali 40, Ramulus Cinnamomi 12, Herba Asari 8, Semen Persicae 12, Radix Paeoniae Rubra 15, Radix Achyranthis Bidentatae 15, Herba Aristolochiae Mollissimae 30, Ophidia black snake powder 30, Radix Glycyrrhizae 6 and Scolopendra powder 1.
Its preparation method is:
Get Radix Aconiti Preparata 12, Herba Ephedrae 10, the Radix Astragali 40, Ramulus Cinnamomi 12, Herba Asari 8, Semen Persicae 12, Radix Paeoniae Rubra 15, Radix Achyranthis Bidentatae 15, Herba Aristolochiae Mollissimae 30, Ophidia black snake powder 30, Radix Glycyrrhizae 6 and Scolopendra powder 1;
Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour;
Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; Add suitable adjuvant magnesium stearate, the tablet machine tabletting, coating promptly gets tablet.
Embodiment 4
A kind of Chinese medicine for the treatment of rheumatoid arthritis in weight portion, comprises following component: Radix Aconiti Preparata 12, Herba Ephedrae 10, the Radix Astragali 40, Ramulus Cinnamomi 12, Herba Asari 8, Semen Persicae 12, Radix Paeoniae Rubra 15, Radix Achyranthis Bidentatae 15, Herba Aristolochiae Mollissimae 30, Ophidia black snake powder 30, Radix Glycyrrhizae 6 and Scolopendra powder 1.
Its preparation method is:
Get Radix Aconiti Preparata 12, Herba Ephedrae 10, the Radix Astragali 40, Ramulus Cinnamomi 12, Herba Asari 8, Semen Persicae 12, Radix Paeoniae Rubra 15, Radix Achyranthis Bidentatae 15, Herba Aristolochiae Mollissimae 30, Ophidia black snake powder 30, Radix Glycyrrhizae 6 and Scolopendra powder 1;
Cleaning, drying mix above-mentioned medical material, and pulverizing with pulverizer is 150-180 order fine powder, and add suitable Mel and mix, the pellet processing machine pill, cold drying, packing promptly gets pill.
Claims (4)
1. Chinese medicine for the treatment of rheumatoid arthritis, it is characterized in that, in weight portion, comprise following component: Radix Aconiti Preparata 10-14, Herba Ephedrae 8-12, Radix Astragali 35-45, Ramulus Cinnamomi 10-14, Herba Asari 6-10, Semen Persicae 10-14, Radix Paeoniae Rubra 12-18, Radix Achyranthis Bidentatae 12-18, Herba Aristolochiae Mollissimae 25-35, Zaocys 25-35, Radix Glycyrrhizae 4-8 and Scolopendra powder 0.5-1.5.
2. Chinese medicine according to claim 1, it is characterized in that, in weight portion, preferably comprise following component: Radix Aconiti Preparata 12, Herba Ephedrae 10, the Radix Astragali 40, Ramulus Cinnamomi 12, Herba Asari 8, Semen Persicae 12, Radix Paeoniae Rubra 15, Radix Achyranthis Bidentatae 15, Herba Aristolochiae Mollissimae 30, Zaocys 30, Radix Glycyrrhizae 6 and Scolopendra powder 1.
3. Chinese medicine according to claim 1 and 2 is characterized in that, described Chinese medicine adopts tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.
4. Chinese medicine according to claim 3 is characterized in that, described Chinese medicine adopts solution, tablet, granule and pill.
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| CN2011102328375A CN102266404A (en) | 2011-08-15 | 2011-08-15 | Traditional Chinese medicine for treating rheumatoid arthritis |
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| CN2011102328375A CN102266404A (en) | 2011-08-15 | 2011-08-15 | Traditional Chinese medicine for treating rheumatoid arthritis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105012553A (en) * | 2015-08-14 | 2015-11-04 | 周功浪 | Traditional Chinese medicine for treating costal chondritis |
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2011
- 2011-08-15 CN CN2011102328375A patent/CN102266404A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105012553A (en) * | 2015-08-14 | 2015-11-04 | 周功浪 | Traditional Chinese medicine for treating costal chondritis |
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Application publication date: 20111207 |