CN102265873A - Application of artemether as algae inhibiting agent - Google Patents
Application of artemether as algae inhibiting agent Download PDFInfo
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- CN102265873A CN102265873A CN2011101294812A CN201110129481A CN102265873A CN 102265873 A CN102265873 A CN 102265873A CN 2011101294812 A CN2011101294812 A CN 2011101294812A CN 201110129481 A CN201110129481 A CN 201110129481A CN 102265873 A CN102265873 A CN 102265873A
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- algae
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- artemether
- inhibiting
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Abstract
The invention provides application of artemether as an algae inhibiting agent. Artemisinin simple ether derivatives have a good inhibition effect on copper aluminum microcystis, scenedesmus obliqnus and the like. The artemisinin simple ether derivatives can be prepared into missible oil, clathrate, slow release microcapsules and the like as algae inhibiting agents applied in nature water bodies like ponds, reservoirs and lakes for inhibiting algae booms.
Description
Technical field
The invention belongs to water pollution control field, particularly with of the application of traditional antimalarial agent qinghaosu simple ether analog derivative, for qinghaosu simple ether analog derivative provides new application as algae-inhibiting agent.
Background technology
Qinghaosu is the effective monomer component (sesquiterpene lactone peroxide) that extracts from China traditional Chinese medicine artemisia annua, has good antimalarial effect, has been new antimalarial by world health organisation recommendations.At present, the main application fields of qinghaosu simple ether analog derivative still is fields such as antimalarial medication and antimycotic, antibacterium, antitumor, anticancer, anti-blood sucker, also is not used as algae-inhibiting agent and uses
In the prior art, the method for control water body algal tufa mainly contains physics method, chemical method and bioanalysis, and wherein the method for normal use is a chemical method.Existing chemical algae-inhibiting agent mainly is CuSO
4, its mechanism is to utilize the toxicity of copper ion to remove to disturb the algae photosynthetic reaction system, makes it normally to carry out photosynthesis, and finally reaches the purpose of killing algae.Yet copper ion is a heavy metal ion, and biological selectivity is low, by other water plants and animal absorption or picked-up, may cause other hydrobiological death, and perhaps accumulation in vivo damages finally for ecotope and human health.
The allelochemical effect of algae restraint that plant produced is obvious, environmental friendliness, so it becomes trend as novel algae-inhibiting agent.The allelochemical that suppresses algae and water at present is extracted from water plants mostly, yet water plants is subjected to environmental condition and limits, and is difficult for plantation on a large scale and results, has limited the extraction of allelochemical.In addition, extract allelochemical from the water plants body, have the separation costs height, difficulty is big, is difficult for shortcomings such as use in practice.
Summary of the invention
The technical problem that solves:In order to overcome existing algae-inhibiting agent shortcoming, simultaneously, expand new application for conventional medicament qinghaosu simple ether analog derivative, the present invention is applied to qinghaosu simple ether analog derivative in the natural waters such as pond, lake, reservoir as algae-inhibiting agent, suppresses the outburst of algae.
Technical scheme:SM-224 is as the application of algae-inhibiting agent, and the structural formula of described SM-224 is:
Wherein R is an alkyl; Described R is methane machine or ethyl group; Described algae is microcystic aeruginosa or scenedesmus obliquus.
Beneficial effect:
Qinghaosu simple ether analog derivative is synthetic by qinghaosu, and for falling thing, the environment compatibility is good, and is lower to higher mammal toxicity, has wide range of applications as algae-inhibiting agent.The present invention is by the research to the indoor algal control effect of qinghaosu simple ether analog derivative, confirmed that qinghaosu simple ether analog derivative all has copper aluminium Microcystis aeruginosa, scenedesmus obliquus etc. to suppress effect preferably.
Embodiment
Embodiment 1:
Use the artemisinin derivative Artemether that the microcystic aeruginosa of aseptic culture is carried out acute toxicity testing, sets some concentration gradients, it is parallel that blank and two groups are set, and observation in per 24 hours was once observed 5 days continuously.The result shows, when Artemether concentration reaches 2mg/L when above, the effective inhibiting rate of its 96h to microcystic aeruginosa reaches more than 95%.
Embodiment 2:
Use the artemisinin derivative arteether that the scenedesmus obliquus of aseptic culture is carried out acute toxicity testing, sets some concentration gradients, it is parallel that blank and two groups are set, and observation in per 24 hours was once observed 5 days continuously.The result shows, when arteether concentration reaches 2mg/L when above, the effective inhibiting rate of its 96h to microcystic aeruginosa reaches more than 94%.
Claims (3)
1. SM-224 is as the application of algae-inhibiting agent, and the structural formula of described SM-224 is:
Wherein R is an alkyl.
2. qinghaosu according to claim 1 is characterized in that as the application of algae-inhibiting agent described R is methyl or ethyl group.
3. qinghaosu according to claim 1 is characterized in that as the application of algae-inhibiting agent described algae is microcystic aeruginosa or scenedesmus obliquus.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110129481 CN102265873B (en) | 2011-05-19 | 2011-05-19 | Application of artemether as algae inhibiting agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110129481 CN102265873B (en) | 2011-05-19 | 2011-05-19 | Application of artemether as algae inhibiting agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102265873A true CN102265873A (en) | 2011-12-07 |
| CN102265873B CN102265873B (en) | 2013-05-08 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201110129481 Expired - Fee Related CN102265873B (en) | 2011-05-19 | 2011-05-19 | Application of artemether as algae inhibiting agent |
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| CN (1) | CN102265873B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102578110A (en) * | 2011-12-23 | 2012-07-18 | 河海大学 | Preparation method of artemisinin slow-release body |
| CN104082285A (en) * | 2014-06-25 | 2014-10-08 | 河海大学 | Artemisinin missible oil algaecide, and preparation method and application thereof |
| CN107509736A (en) * | 2017-09-05 | 2017-12-26 | 河海大学 | A kind of compound algae-inhibiting agent and its preparation method and application |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101731284A (en) * | 2009-12-03 | 2010-06-16 | 河海大学 | Method for extracting alga-inhibiting active ingredients from Artemisia annua L. and alga-inhibiting method |
-
2011
- 2011-05-19 CN CN 201110129481 patent/CN102265873B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101731284A (en) * | 2009-12-03 | 2010-06-16 | 河海大学 | Method for extracting alga-inhibiting active ingredients from Artemisia annua L. and alga-inhibiting method |
Non-Patent Citations (2)
| Title |
|---|
| PETER K. CHEN ET AL.: "PLANT GROWTH REGULATORY ACTIVITIES OF ARTEMISININ AND ITS RELATED COMPOUNDS", 《JOURNAL OF CHEMICAL ECOLOGY》 * |
| VIKAS DHINGRA ET AL.: "Artemisinin: present status and perspectives", 《BIOCHEMICAL EDUCATION》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102578110A (en) * | 2011-12-23 | 2012-07-18 | 河海大学 | Preparation method of artemisinin slow-release body |
| CN104082285A (en) * | 2014-06-25 | 2014-10-08 | 河海大学 | Artemisinin missible oil algaecide, and preparation method and application thereof |
| CN107509736A (en) * | 2017-09-05 | 2017-12-26 | 河海大学 | A kind of compound algae-inhibiting agent and its preparation method and application |
| CN107509736B (en) * | 2017-09-05 | 2020-10-02 | 河海大学 | Composite algistat and preparation method and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102265873B (en) | 2013-05-08 |
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